BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is bdhA [H]

Identifier: 13474375

GI number: 13474375

Start: 4178480

End: 4179307

Strand: Direct

Name: bdhA [H]

Synonym: mlr5248

Alternate gene names: 13474375

Gene position: 4178480-4179307 (Clockwise)

Preceding gene: 13474374

Following gene: 13474376

Centisome position: 59.39

GC content: 67.03

Gene sequence:

>828_bases
ATGACAAACCTTGCAGGGCGCGGTGCAATCGTCACCGGCGGCTTTTCGGGCATGGGCTTCGCCATTGCCTCGGCCTTGGC
TGAAGCTGGCGCCAATGTCGCCGTCGGGTCCTACATCGCGCCTGCCGGCACCGACAGATCCGACGCCGCCTATTATCCGG
GCATCGACGAAATCGAGCGCGTGCGGTCGGCCTTGTCTGCCCATGGCACCAGGGTGCACGCTGCTCACCTCGATGTCCGC
GACAGCGAGGTCACCAACCGTTTCGTCGCCGAAGCCGAGGCCGCCATCGGTCCTGCCGACATCCTGGTCAACGCGGCCGG
CACCACCACCGAGCAACCGGTTTGCGGACATTCCGACGCGCTGTGGGACAAGATCGTCGACACCAACCTGACCGGCGCCT
TCCGCACCACCCGTGCCGTGCTTCCCGGCATGATCGCGCGCGGCTGGGGCCGCATCGTCAACATCGGCTCGACCGCGGCT
TCCGTCGGCTGGAAGGACAACCCCGCCTACTGCGCCTCCAAGGCCGGCCTGCTCGGCCTCACCCGCTGCGTGGCGCTGGA
GGGGGCGGCGCACGGCGTCACCTGCGTCATGATCAGCCCGACCTGGGTCGAGACCGAATTGATGCGCCGCAACGTGGCAC
AGGTCGTCGAGCGCGAGGGCAAGGGGCGGACGGCGCAGCAAGCGATGGCCGAGATCGCCAAGGGCAACCCGCAGCAGCGC
ATGCTGCAGCCGCAGGAAATCGCCGCACTGGCCGTATTCCTGTGCTCGGACCTGGCCAAAGGCATCACCATGGAAAACAT
ACAGATCACCGGCGGAGCACTCTGGTAG

Upstream 100 bases:

>100_bases
AGGCTTCTATCGCGAATGGCTGGGCAAGCCGCTTTAGCGAACCGCGTCGACAAATACTGCGGAACCTGATTGCTTGCCCC
AACCATTGGAGAAGCACGCG

Downstream 100 bases:

>100_bases
CATTCTCGTGCCTGATCCAGGCGGCTGTCTCGGGGCGGGCCACAGGCTGATCTCTCCCCGTTCGCCACAGTAATTCCAGG
ATAAGTGTGAACGGTTTTCC

Product: beta-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTNLAGRGAIVTGGFSGMGFAIASALAEAGANVAVGSYIAPAGTDRSDAAYYPGIDEIERVRSALSAHGTRVHAAHLDVR
DSEVTNRFVAEAEAAIGPADILVNAAGTTTEQPVCGHSDALWDKIVDTNLTGAFRTTRAVLPGMIARGWGRIVNIGSTAA
SVGWKDNPAYCASKAGLLGLTRCVALEGAAHGVTCVMISPTWVETELMRRNVAQVVEREGKGRTAQQAMAEIAKGNPQQR
MLQPQEIAALAVFLCSDLAKGITMENIQITGGALW

Sequences:

>Translated_275_residues
MTNLAGRGAIVTGGFSGMGFAIASALAEAGANVAVGSYIAPAGTDRSDAAYYPGIDEIERVRSALSAHGTRVHAAHLDVR
DSEVTNRFVAEAEAAIGPADILVNAAGTTTEQPVCGHSDALWDKIVDTNLTGAFRTTRAVLPGMIARGWGRIVNIGSTAA
SVGWKDNPAYCASKAGLLGLTRCVALEGAAHGVTCVMISPTWVETELMRRNVAQVVEREGKGRTAQQAMAEIAKGNPQQR
MLQPQEIAALAVFLCSDLAKGITMENIQITGGALW
>Mature_274_residues
TNLAGRGAIVTGGFSGMGFAIASALAEAGANVAVGSYIAPAGTDRSDAAYYPGIDEIERVRSALSAHGTRVHAAHLDVRD
SEVTNRFVAEAEAAIGPADILVNAAGTTTEQPVCGHSDALWDKIVDTNLTGAFRTTRAVLPGMIARGWGRIVNIGSTAAS
VGWKDNPAYCASKAGLLGLTRCVALEGAAHGVTCVMISPTWVETELMRRNVAQVVEREGKGRTAQQAMAEIAKGNPQQRM
LQPQEIAALAVFLCSDLAKGITMENIQITGGALW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=273, Percent_Identity=29.6703296703297, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI32483357, Length=270, Percent_Identity=30.3703703703704, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=28.158844765343, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5031737, Length=278, Percent_Identity=30.2158273381295, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4504505, Length=256, Percent_Identity=29.6875, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=273, Percent_Identity=28.9377289377289, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI40807363, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7705925, Length=205, Percent_Identity=31.219512195122, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=249, Percent_Identity=30.1204819277108, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7657478, Length=236, Percent_Identity=31.3559322033898, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI20149619, Length=269, Percent_Identity=26.7657992565056, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254992, Length=265, Percent_Identity=27.9245283018868, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI126723750, Length=273, Percent_Identity=27.1062271062271, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=32.9842931937173, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=207, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=201, Percent_Identity=29.3532338308458, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=201, Percent_Identity=29.3532338308458, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=201, Percent_Identity=29.3532338308458, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=224, Percent_Identity=29.4642857142857, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=274, Percent_Identity=33.5766423357664, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787335, Length=270, Percent_Identity=32.2222222222222, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790717, Length=274, Percent_Identity=28.4671532846715, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082160, Length=272, Percent_Identity=28.3088235294118, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789208, Length=273, Percent_Identity=30.03663003663, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786812, Length=272, Percent_Identity=30.5147058823529, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=267, Percent_Identity=26.9662921348315, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789378, Length=274, Percent_Identity=26.2773722627737, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=141, Percent_Identity=36.8794326241135, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=271, Percent_Identity=27.3062730627306, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367175, Length=271, Percent_Identity=28.0442804428044, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789057, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=271, Percent_Identity=29.520295202952, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=273, Percent_Identity=31.5018315018315, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=272, Percent_Identity=27.2058823529412, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=277, Percent_Identity=29.6028880866426, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=27.0935960591133, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=205, Percent_Identity=28.780487804878, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=280, Percent_Identity=27.5, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=289, Percent_Identity=26.643598615917, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=278, Percent_Identity=27.3381294964029, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=296, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=27.3076923076923, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.4809160305344, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=267, Percent_Identity=25.4681647940075, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=209, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=28.9340101522843, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=208, Percent_Identity=27.4038461538462, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=276, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24639444, Length=272, Percent_Identity=29.7794117647059, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI23397609, Length=272, Percent_Identity=31.25, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21357041, Length=272, Percent_Identity=28.6764705882353, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644339, Length=271, Percent_Identity=27.6752767527675, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356301, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24643142, Length=271, Percent_Identity=26.1992619926199, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=212, Percent_Identity=25.9433962264151, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665243, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571526, Length=272, Percent_Identity=25.3676470588235, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 28661; Mature: 28530

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLAGRGAIVTGGFSGMGFAIASALAEAGANVAVGSYIAPAGTDRSDAAYYPGIDEIER
CCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEECCEECCCCCCCCCCCCCCCHHHHHH
VRSALSAHGTRVHAAHLDVRDSEVTNRFVAEAEAAIGPADILVNAAGTTTEQPVCGHSDA
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCHH
LWDKIVDTNLTGAFRTTRAVLPGMIARGWGRIVNIGSTAASVGWKDNPAYCASKAGLLGL
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHCCCCCCCCHHHHCCCHHHH
TRCVALEGAAHGVTCVMISPTWVETELMRRNVAQVVEREGKGRTAQQAMAEIAKGNPQQR
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHH
MLQPQEIAALAVFLCSDLAKGITMENIQITGGALW
CCCHHHHHHHHHHHHHHHHHCCEECEEEECCCCCC
>Mature Secondary Structure 
TNLAGRGAIVTGGFSGMGFAIASALAEAGANVAVGSYIAPAGTDRSDAAYYPGIDEIER
CCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEECCEECCCCCCCCCCCCCCCHHHHHH
VRSALSAHGTRVHAAHLDVRDSEVTNRFVAEAEAAIGPADILVNAAGTTTEQPVCGHSDA
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCHH
LWDKIVDTNLTGAFRTTRAVLPGMIARGWGRIVNIGSTAASVGWKDNPAYCASKAGLLGL
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHCCCCCCCCHHHHCCCHHHH
TRCVALEGAAHGVTCVMISPTWVETELMRRNVAQVVEREGKGRTAQQAMAEIAKGNPQQR
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHH
MLQPQEIAALAVFLCSDLAKGITMENIQITGGALW
CCCHHHHHHHHHHHHHHHHHCCEECEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]