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The map label for this gene is xylA

Identifier: 13474199

GI number: 13474199

Start: 3985893

End: 3987218

Strand: Direct

Name: xylA

Synonym: mlr5036

Alternate gene names: 13474199

Gene position: 3985893-3987218 (Clockwise)

Preceding gene: 13474197

Following gene: 13474200

Centisome position: 56.65

GC content: 63.2

Gene sequence:

>1326_bases
ATGAGCAGCGGATTTTTCGGCGACATCCAGAAGATCAAATATGAGGGGCCGGATTCGACCAATCCGCTGGCCTACCGCTT
CTACAATCCGGACGAGGTGGTGGCCGGCAAGCGGCTGGAAGACCATCTGCGCTTCGCTGTCGCCTACTGGCATTCCTTCG
CCTGGCCGGGTGGCGACCCCTTCGGCGGCCAGACCTTCGACCGCCCCTGGTTCCCCAAGGCTGGCGGCATCGACACGATG
GAACTGGCGAAGCTCAAGGCCGATGTTGCCTTCGAGATGTTCTCGCTGCTCGGCGCGCCCTATTTCTGCTTCCACGACGC
CGACGTCCGCCCCGAGGGCAAGGACTTTTCCGAAAGTGCCGCCCGCCTCGACGAGATCGCGGACTACTTTGCCGGCAAGA
TGAAGCAGACCGGGGTCAAGCTGCTCTGGGGTACCGCGAACCTCTTCTCGCACCGCCGCTTCATGTCAGGCGCCGCCACC
AATCCCGATCCGGATGTCTTTGCCTATGCGGCGGCGACGGTGAAAAGCTGCATCGACGTCACCAAGCGGCTGAAAGGCGA
GAACTATGTGCTGTGGGGCGGGCGCGAAGGCTATGAGACGCTGCTCAACACCGACCTTGCCCGCGAGCAGGAACAGGCGG
GCCGCTTCCTCAGCCTCGTCGTCGACTACAAGCACAAGATCGGTTTCAAGGGCACCATCCTGATCGAGCCGAAGCCGCAG
GAGCCGACAAAGCATCAGTACGACTATGACGTCGCAACCGTCTATGGCTTCCTCAAGCGCTTCGGCCTGGAGAAGGAGGT
CAAGCTCAACATCGAGCAGGGCCACGCCATCCTTGCCGGCCACTCCTTCGAGCACGAGCTGGCGCTCGCCAATGCCCTCG
GCGTCTTCGGTTCGATCGATATGAACCGCAACGACTACCAGTCGGGCTGGGACACCGACCAGTTCCCCAACAACGTGCCG
GAAATGGCGCTGGCCTACTACCAGATCCTGCAGGCCGGTGGCTTCAAGACCGGCGGCACCAATTTCGACGCCAAGCTGCG
CCGCCAGTCGCTCGACCCGCAGGACCTGCTGATCGGCCATATCGGCGGCATGGATGCCTGCGCACGCGGTCTCAAGGCCG
CGGCCCGCATGGTCGAGGACAAGGCGCTGTCGGCGCCGCTGGCCGAGCGCTATGCCGGTTGGAACTCGGCAGAGGGCAAG
GCGATGCTGTCAGGCAAGCGCACGCTGGAGGACATCGCCGAGCGCGTGGTCAAGAAGAAGATCGAACCGCAGCCGCGCTC
CGGCCGCCAGGAATTGCTGGAAAACATCGTCAACCGCTACGTCTGA

Upstream 100 bases:

>100_bases
TGCTTGATGGCTTTGACACGACCCTTTTCACCCCACGGCAGACCGAAACCAATTACGCCTGAGGTAATCAAGGCGAACTA
TTCGAGAGAGGACAGAAATC

Downstream 100 bases:

>100_bases
GGTGTCTTGCAGTGCCCGATTCGGGCGCCACAGAGCTGAAAATTGCATTCCGCACGGGGTGGAACCACACGAGCATGATG
GGGCTCGGCGAGGCGTTGGA

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSSGFFGDIQKIKYEGPDSTNPLAYRFYNPDEVVAGKRLEDHLRFAVAYWHSFAWPGGDPFGGQTFDRPWFPKAGGIDTM
ELAKLKADVAFEMFSLLGAPYFCFHDADVRPEGKDFSESAARLDEIADYFAGKMKQTGVKLLWGTANLFSHRRFMSGAAT
NPDPDVFAYAAATVKSCIDVTKRLKGENYVLWGGREGYETLLNTDLAREQEQAGRFLSLVVDYKHKIGFKGTILIEPKPQ
EPTKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALANALGVFGSIDMNRNDYQSGWDTDQFPNNVP
EMALAYYQILQAGGFKTGGTNFDAKLRRQSLDPQDLLIGHIGGMDACARGLKAAARMVEDKALSAPLAERYAGWNSAEGK
AMLSGKRTLEDIAERVVKKKIEPQPRSGRQELLENIVNRYV

Sequences:

>Translated_441_residues
MSSGFFGDIQKIKYEGPDSTNPLAYRFYNPDEVVAGKRLEDHLRFAVAYWHSFAWPGGDPFGGQTFDRPWFPKAGGIDTM
ELAKLKADVAFEMFSLLGAPYFCFHDADVRPEGKDFSESAARLDEIADYFAGKMKQTGVKLLWGTANLFSHRRFMSGAAT
NPDPDVFAYAAATVKSCIDVTKRLKGENYVLWGGREGYETLLNTDLAREQEQAGRFLSLVVDYKHKIGFKGTILIEPKPQ
EPTKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALANALGVFGSIDMNRNDYQSGWDTDQFPNNVP
EMALAYYQILQAGGFKTGGTNFDAKLRRQSLDPQDLLIGHIGGMDACARGLKAAARMVEDKALSAPLAERYAGWNSAEGK
AMLSGKRTLEDIAERVVKKKIEPQPRSGRQELLENIVNRYV
>Mature_440_residues
SSGFFGDIQKIKYEGPDSTNPLAYRFYNPDEVVAGKRLEDHLRFAVAYWHSFAWPGGDPFGGQTFDRPWFPKAGGIDTME
LAKLKADVAFEMFSLLGAPYFCFHDADVRPEGKDFSESAARLDEIADYFAGKMKQTGVKLLWGTANLFSHRRFMSGAATN
PDPDVFAYAAATVKSCIDVTKRLKGENYVLWGGREGYETLLNTDLAREQEQAGRFLSLVVDYKHKIGFKGTILIEPKPQE
PTKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALANALGVFGSIDMNRNDYQSGWDTDQFPNNVPE
MALAYYQILQAGGFKTGGTNFDAKLRRQSLDPQDLLIGHIGGMDACARGLKAAARMVEDKALSAPLAERYAGWNSAEGKA
MLSGKRTLEDIAERVVKKKIEPQPRSGRQELLENIVNRYV

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=437, Percent_Identity=60.4118993135012, Blast_Score=566, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_RHILO (Q98CR8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105767.1
- ProteinModelPortal:   Q98CR8
- SMR:   Q98CR8
- GeneID:   1228428
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr5036
- NMPDR:   fig|266835.1.peg.3871
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- BRENDA:   5.3.1.5
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49244; Mature: 49113

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 105-105 ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGFFGDIQKIKYEGPDSTNPLAYRFYNPDEVVAGKRLEDHLRFAVAYWHSFAWPGGDP
CCCCCCCCHHHEEECCCCCCCCEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
FGGQTFDRPWFPKAGGIDTMELAKLKADVAFEMFSLLGAPYFCFHDADVRPEGKDFSESA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHH
ARLDEIADYFAGKMKQTGVKLLWGTANLFSHRRFMSGAATNPDPDVFAYAAATVKSCIDV
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
TKRLKGENYVLWGGREGYETLLNTDLAREQEQAGRFLSLVVDYKHKIGFKGTILIEPKPQ
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
EPTKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALANALGVFGSID
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCC
MNRNDYQSGWDTDQFPNNVPEMALAYYQILQAGGFKTGGTNFDAKLRRQSLDPQDLLIGH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHEEC
IGGMDACARGLKAAARMVEDKALSAPLAERYAGWNSAEGKAMLSGKRTLEDIAERVVKKK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHH
IEPQPRSGRQELLENIVNRYV
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSGFFGDIQKIKYEGPDSTNPLAYRFYNPDEVVAGKRLEDHLRFAVAYWHSFAWPGGDP
CCCCCCCHHHEEECCCCCCCCEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
FGGQTFDRPWFPKAGGIDTMELAKLKADVAFEMFSLLGAPYFCFHDADVRPEGKDFSESA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHH
ARLDEIADYFAGKMKQTGVKLLWGTANLFSHRRFMSGAATNPDPDVFAYAAATVKSCIDV
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
TKRLKGENYVLWGGREGYETLLNTDLAREQEQAGRFLSLVVDYKHKIGFKGTILIEPKPQ
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
EPTKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALANALGVFGSID
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCC
MNRNDYQSGWDTDQFPNNVPEMALAYYQILQAGGFKTGGTNFDAKLRRQSLDPQDLLIGH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHEEC
IGGMDACARGLKAAARMVEDKALSAPLAERYAGWNSAEGKAMLSGKRTLEDIAERVVKKK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHH
IEPQPRSGRQELLENIVNRYV
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968