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The map label for this gene is dapD

Identifier: 13474056

GI number: 13474056

Start: 3850941

End: 3851795

Strand: Direct

Name: dapD

Synonym: mlr4843

Alternate gene names: 13474056

Gene position: 3850941-3851795 (Clockwise)

Preceding gene: 13474054

Following gene: 13474057

Centisome position: 54.73

GC content: 65.61

Gene sequence:

>855_bases
ATGTCGAAGCCCGATCTGGCGAGCCTCGAAAAGACCATCGAGAAGGCCTTCGACGAACGCGACGCGATTTCGACCGCGAC
CCGTGGCGAGACGCGCGACGCCATCCAGGCCGCGCTCGACCTGCTCGACCGCGGCACGGTGCGCGTCGCCGAGCGCCAGG
CCGACGGCAAGTGGCACGTCAATCAGTGGCTGAAGAAGGCCGTGCTGCTCTCCTTCCGACTCAACCCGATGGAGATCATC
AAGGGCGGCCCGGGCCAGGCCGTCTGGTGGGACAAGGTGCCGTCCAAGTTCGATGGCTGGAGCGCCGTCGATTTCGAGAA
GGCGGGTTTTCGCGCGGTGCCGTCGTCGATCGTGCGCCGTTCCGCCTATGTCGCGCCGGGCGCCGTGCTCATGCCATCCT
TCGTCAATGTCGGCGCCTATGTCGACACGGGCACCATGGTCGACACCTGGGCCTCGGTCGGTTCCTGTGCGCAGATCGGC
AAGAACGTGCATCTGTCGGGCGGTGTCGGCATCGGCGGCGTGCTCGAGCCGATGCAGGCCGGCCCCACCATCATCGAGGA
CAATTGCTTCATCGGCGCGCGTTCGGAAGTCGTCGAGGGCTGCATCGTGCGCGAAGGCTCGGTGCTCGGCATGGGCGTCT
TCATCGGCCAGTCGACCAAGATCGTCGACCGCGCCACGGGCGAGATCTTTTACGGCGAAGTGCCGCCCAATTCGGTGGTT
GTTGCCGGCTCGCTGCCGGGCAAGCCTTTTCCGAACAACGAGCCTGGCCCCGGCCTCTACTGCGCCGTCATCGTCAAGCG
CGTCGACGCCAAGACCCGGTCCAAGACCTCGATCAACGAATTGCTGCGCGATTGA

Upstream 100 bases:

>100_bases
ACATGCAAAGACCCAGGCAGGCGAAGCACGCCCAGGGTCCACGCGACTTCAAAACAGGTTAAGGCGCAGCCCCTTAACAG
CTTGGTAATGGAGCGAATTC

Downstream 100 bases:

>100_bases
TCTTTCCGCAAAGCGGGCGCACCTTCCGCCGGCGCGTCAATCGGTCGCGCTGGTTCAACATGGAGGGGTGACATGGACTG
GAAATATCTGCTGACGAGTT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSKPDLASLEKTIEKAFDERDAISTATRGETRDAIQAALDLLDRGTVRVAERQADGKWHVNQWLKKAVLLSFRLNPMEII
KGGPGQAVWWDKVPSKFDGWSAVDFEKAGFRAVPSSIVRRSAYVAPGAVLMPSFVNVGAYVDTGTMVDTWASVGSCAQIG
KNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRATGEIFYGEVPPNSVV
VAGSLPGKPFPNNEPGPGLYCAVIVKRVDAKTRSKTSINELLRD

Sequences:

>Translated_284_residues
MSKPDLASLEKTIEKAFDERDAISTATRGETRDAIQAALDLLDRGTVRVAERQADGKWHVNQWLKKAVLLSFRLNPMEII
KGGPGQAVWWDKVPSKFDGWSAVDFEKAGFRAVPSSIVRRSAYVAPGAVLMPSFVNVGAYVDTGTMVDTWASVGSCAQIG
KNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRATGEIFYGEVPPNSVV
VAGSLPGKPFPNNEPGPGLYCAVIVKRVDAKTRSKTSINELLRD
>Mature_283_residues
SKPDLASLEKTIEKAFDERDAISTATRGETRDAIQAALDLLDRGTVRVAERQADGKWHVNQWLKKAVLLSFRLNPMEIIK
GGPGQAVWWDKVPSKFDGWSAVDFEKAGFRAVPSSIVRRSAYVAPGAVLMPSFVNVGAYVDTGTMVDTWASVGSCAQIGK
NVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRATGEIFYGEVPPNSVVV
AGSLPGKPFPNNEPGPGLYCAVIVKRVDAKTRSKTSINELLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=279, Percent_Identity=62.3655913978495, Blast_Score=320, Evalue=5e-89,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_RHILO (Q98D61)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105624.1
- ProteinModelPortal:   Q98D61
- SMR:   Q98D61
- GeneID:   1228285
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4843
- NMPDR:   fig|266835.1.peg.3728
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BRENDA:   2.3.1.117
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 30361; Mature: 30230

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 111-111 BINDING 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPDLASLEKTIEKAFDERDAISTATRGETRDAIQAALDLLDRGTVRVAERQADGKWHV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHH
NQWLKKAVLLSFRLNPMEIIKGGPGQAVWWDKVPSKFDGWSAVDFEKAGFRAVPSSIVRR
HHHHHHHHHHHHCCCHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHH
SAYVAPGAVLMPSFVNVGAYVDTGTMVDTWASVGSCAQIGKNVHLSGGVGIGGVLEPMQA
HHHCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHC
GPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRATGEIFYGEVPPNSVV
CCCEEECCCEECCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHCCCCCEEECCCCCCCEE
VAGSLPGKPFPNNEPGPGLYCAVIVKRVDAKTRSKTSINELLRD
EEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHCC
>Mature Secondary Structure 
SKPDLASLEKTIEKAFDERDAISTATRGETRDAIQAALDLLDRGTVRVAERQADGKWHV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHH
NQWLKKAVLLSFRLNPMEIIKGGPGQAVWWDKVPSKFDGWSAVDFEKAGFRAVPSSIVRR
HHHHHHHHHHHHCCCHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHH
SAYVAPGAVLMPSFVNVGAYVDTGTMVDTWASVGSCAQIGKNVHLSGGVGIGGVLEPMQA
HHHCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHC
GPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRATGEIFYGEVPPNSVV
CCCEEECCCEECCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHCCCCCEEECCCCCCCEE
VAGSLPGKPFPNNEPGPGLYCAVIVKRVDAKTRSKTSINELLRD
EEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968