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The map label for this gene is sigK [H]

Identifier: 13474039

GI number: 13474039

Start: 3836084

End: 3836623

Strand: Reverse

Name: sigK [H]

Synonym: mll4824

Alternate gene names: 13474039

Gene position: 3836623-3836084 (Counterclockwise)

Preceding gene: 13474042

Following gene: 13474038

Centisome position: 54.53

GC content: 61.11

Gene sequence:

>540_bases
ATGACGCCGCAGGACATCACCAAGCTGATCGTCCGGACTTCGATGAAGGATCGGGCAGCGTTCGATCTGCTCTACCGGCA
GACCAGCGCGAAACTTTTCGGCGTGTGCCTTCGTGTATTGAACGACCGGGGAGATGCTGAAGAAGCGCTGCAGGAAGTCT
TCGTCAAGATATGGACAAAGGCGGACCGTTTTGCCGTCTCCGATCTGAGCCCGATCTCCTGGCTGGTGGCAATCGCCCGC
AACCACGCGATCGATCGCGTCAGGGCACGGCGTAAGTCTGCCGCCGATATCGATGCCGCGCTCGAGGTGGCCGATCCGGC
ACCGGGACCTGAAGCGATGGTGGTGGCGGGCGACGAATCCCAACGCATCCATCATTGTCTGGAGGAGCTGGAGAAGGACC
GGGCGGCGGCCGTTCGGGGCGCTTATCTCAAGGGCGAAAGCTATGCCGAACTGGCGGAACGCCACGGCGTGCCGCTGAAC
ACGATGCGTACCTGGCTGCGCCGCAGCCTGATGAAACTGAGAGAATGTCTGGAAAGATGA

Upstream 100 bases:

>100_bases
ATCCCTTGGCAATCGAAGCCTGCGCCTGGACACCGGAGCTTTAGGTGCAAGGAATATTTCCGGCGTTGCAAATACAACGC
AATCGCCTAACTTGGTTCGC

Downstream 100 bases:

>100_bases
CACTGGCAGAGGACAATGGACCGGAACGTGGAGGCGACGACCTGCTCGCCGCCGAATACGTTATCGGCGTTCTGCCGGTG
GAAGAGCGGCAGATCGCATC

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTPQDITKLIVRTSMKDRAAFDLLYRQTSAKLFGVCLRVLNDRGDAEEALQEVFVKIWTKADRFAVSDLSPISWLVAIAR
NHAIDRVRARRKSAADIDAALEVADPAPGPEAMVVAGDESQRIHHCLEELEKDRAAAVRGAYLKGESYAELAERHGVPLN
TMRTWLRRSLMKLRECLER

Sequences:

>Translated_179_residues
MTPQDITKLIVRTSMKDRAAFDLLYRQTSAKLFGVCLRVLNDRGDAEEALQEVFVKIWTKADRFAVSDLSPISWLVAIAR
NHAIDRVRARRKSAADIDAALEVADPAPGPEAMVVAGDESQRIHHCLEELEKDRAAAVRGAYLKGESYAELAERHGVPLN
TMRTWLRRSLMKLRECLER
>Mature_178_residues
TPQDITKLIVRTSMKDRAAFDLLYRQTSAKLFGVCLRVLNDRGDAEEALQEVFVKIWTKADRFAVSDLSPISWLVAIARN
HAIDRVRARRKSAADIDAALEVADPAPGPEAMVVAGDESQRIHHCLEELEKDRAAAVRGAYLKGESYAELAERHGVPLNT
MRTWLRRSLMKLRECLER

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 20199; Mature: 20068

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQDITKLIVRTSMKDRAAFDLLYRQTSAKLFGVCLRVLNDRGDAEEALQEVFVKIWTK
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ADRFAVSDLSPISWLVAIARNHAIDRVRARRKSAADIDAALEVADPAPGPEAMVVAGDES
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
QRIHHCLEELEKDRAAAVRGAYLKGESYAELAERHGVPLNTMRTWLRRSLMKLRECLER
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPQDITKLIVRTSMKDRAAFDLLYRQTSAKLFGVCLRVLNDRGDAEEALQEVFVKIWTK
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ADRFAVSDLSPISWLVAIARNHAIDRVRARRKSAADIDAALEVADPAPGPEAMVVAGDES
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
QRIHHCLEELEKDRAAAVRGAYLKGESYAELAERHGVPLNTMRTWLRRSLMKLRECLER
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA