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The map label for this gene is msrB [H]

Identifier: 13474036

GI number: 13474036

Start: 3833879

End: 3834382

Strand: Reverse

Name: msrB [H]

Synonym: mll4820

Alternate gene names: 13474036

Gene position: 3834382-3833879 (Counterclockwise)

Preceding gene: 13474037

Following gene: 13474033

Centisome position: 54.5

GC content: 67.26

Gene sequence:

>504_bases
ATGAACCGTCGCGACTTTCTTTTGAGCGGTGCCGCCGCCATCGGCCTCGTCGGGGCTGCCGCAACGATGCTGCGCATGGG
CAGTCCGCAGGTCGCCCAGGCCGCCGAAAAGTTCGAGGTCACCAAGACCGATGACGAGTGGAAAGCCATCCTGTCGCCGG
CCGCCTTCGACGTGCTGCGCAAGCAAGGCACGGAATATCCGGGCACCAGCCCGCTGCTCAACGAACACCGCAAGGGCATC
TTCGCCTGCGCCGGCTGCGACCTGCCGGTCTACCCCTCGGAAACGAAGTTCGATTCCGGCACCGGCTGGCCGAGCTTCTG
GCAAGAGATCGCCAACGGCATCGGCAAGACCGAGGACAGGTCGCTCGGCATGACCCGCACCGAGGTGCATTGCCGCCGAT
GCGGCGGCCATCTCGGCCACGTCTTCGACGACGGTCCGGCGCCGACCGGCCTGCGCCACTGCATCAACGGCGTGGCGCTG
AGCTTCAAGCCGGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
CAGGGAACGGCGCGGAGTGTTCGTTCGAGGGGCCCGTCACCGGCTTTTGATTTCCGCGTGGCGGCAGAGTTTGGCAAAGA
GACAACAGGAGGAACCGGTC

Downstream 100 bases:

>100_bases
CGAGATTCAGTTGGAAACGAAAAACTCCGGGTCTTGCGGCCCGGAGTTTTTTTCGCGGTCAGAGCTTTTCGGGCGTGGAC
TGGAGGAGCTTCCCGAAACC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNRRDFLLSGAAAIGLVGAAATMLRMGSPQVAQAAEKFEVTKTDDEWKAILSPAAFDVLRKQGTEYPGTSPLLNEHRKGI
FACAGCDLPVYPSETKFDSGTGWPSFWQEIANGIGKTEDRSLGMTRTEVHCRRCGGHLGHVFDDGPAPTGLRHCINGVAL
SFKPAAA

Sequences:

>Translated_167_residues
MNRRDFLLSGAAAIGLVGAAATMLRMGSPQVAQAAEKFEVTKTDDEWKAILSPAAFDVLRKQGTEYPGTSPLLNEHRKGI
FACAGCDLPVYPSETKFDSGTGWPSFWQEIANGIGKTEDRSLGMTRTEVHCRRCGGHLGHVFDDGPAPTGLRHCINGVAL
SFKPAAA
>Mature_167_residues
MNRRDFLLSGAAAIGLVGAAATMLRMGSPQVAQAAEKFEVTKTDDEWKAILSPAAFDVLRKQGTEYPGTSPLLNEHRKGI
FACAGCDLPVYPSETKFDSGTGWPSFWQEIANGIGKTEDRSLGMTRTEVHCRRCGGHLGHVFDDGPAPTGLRHCINGVAL
SFKPAAA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=47.7611940298507, Blast_Score=126, Evalue=8e-30,
Organism=Homo sapiens, GI301336164, Length=128, Percent_Identity=46.875, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI301336162, Length=128, Percent_Identity=46.875, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI73089054, Length=128, Percent_Identity=46.875, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI37620216, Length=128, Percent_Identity=46.875, Blast_Score=123, Evalue=6e-29,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=47.0588235294118, Blast_Score=118, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17553450, Length=121, Percent_Identity=42.9752066115703, Blast_Score=106, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=121, Percent_Identity=42.9752066115703, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=141, Percent_Identity=39.0070921985816, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221378662, Length=138, Percent_Identity=39.1304347826087, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221378664, Length=131, Percent_Identity=41.2213740458015, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24645799, Length=140, Percent_Identity=37.8571428571429, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=40.4761904761905, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=40.4761904761905, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24645801, Length=151, Percent_Identity=35.0993377483444, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=37.2262773722628, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17876; Mature: 17876

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRDFLLSGAAAIGLVGAAATMLRMGSPQVAQAAEKFEVTKTDDEWKAILSPAAFDVLR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
KQGTEYPGTSPLLNEHRKGIFACAGCDLPVYPSETKFDSGTGWPSFWQEIANGIGKTEDR
HCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
SLGMTRTEVHCRRCGGHLGHVFDDGPAPTGLRHCINGVALSFKPAAA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MNRRDFLLSGAAAIGLVGAAATMLRMGSPQVAQAAEKFEVTKTDDEWKAILSPAAFDVLR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
KQGTEYPGTSPLLNEHRKGIFACAGCDLPVYPSETKFDSGTGWPSFWQEIANGIGKTEDR
HCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
SLGMTRTEVHCRRCGGHLGHVFDDGPAPTGLRHCINGVALSFKPAAA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA