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The map label for this gene is fpr [H]

Identifier: 13474009

GI number: 13474009

Start: 3804621

End: 3805448

Strand: Reverse

Name: fpr [H]

Synonym: mll4785

Alternate gene names: 13474009

Gene position: 3805448-3804621 (Counterclockwise)

Preceding gene: 13474014

Following gene: 13474008

Centisome position: 54.08

GC content: 62.92

Gene sequence:

>828_bases
ATGAACACCACATCCGCCTTCAACACCGCCGGCGCCCGCCCGCTGCAGTTTCCTATACCGGCCAATGTCTATGCCGAAAC
CGTCGTCTCGGTGAAGCACTACACCGACCGGCTGTTCTCTTTCCGCATCACCCGTCCGCAGTCGCTGCGCTTCCGCTCCG
GCGAATTCGTCATGATCGGCCTGCCCAATGCCGAGAAGCCGGTGTTCCGTGCCTATTCGGTCGCAAGCCCGGCCTGGGAC
GAAGAGCTGGAATTCTTCTCGATCAAGGTGCCGGACGGCCCGCTGACCTCGGAACTGCAGAAGATCCAGGTCGGCGACAC
CGTCATCATGCGCCAGAAGTCGACCGGGACCCTGGTGGTCGACGCGCTGACCCCGGCCAAGCGGCTGTTCATGATCTCGA
CCGGCACCGGCATCGCGCCCTTCGCCAGCCTGCTGCGCGACCCCGACACCTATGAGAAATTCGACCAGCTGATCCTGACC
CATACCTGCCGCGACAATGCCGAGCTGACCTACGGCCAGGAATTGGTGGCGGCGCTGGAAAGCGACCCGCTGATCGGCGA
ACTGACCACCGGGCGCGTCACGCTCTACAATTCGACGACCCGCGAAGAATCGGCCCGCATGGGCCGCATCACCGCGCTGA
TCGGTTCAGGCAAGTTCTACGCCGACCTTGGCATCGACAAGCTCAATCCGGAAACGGACCGCATCATGATCTGCGGCTCG
ATGCATATGCTCAAGGATGTCAAGGAACTCGCCGAAAGCCTCGGCTTCCAGGAAGGCTCGCTCAGCCATCCCGCGACCTT
CGTCGTCGAGCGCGCCTTCGTCGGCTGA

Upstream 100 bases:

>100_bases
CTTTGGAGTGTGCGAACAGCACGCCGGGACCTGAACGGTCCGGGCGCGCAGGAAAAGGTTTGGCGCCCGCGTCCCCGGTT
GGGCCAGAAAGTTGGATTTG

Downstream 100 bases:

>100_bases
GGCGGACGCCGACACCTCAGACCTGCATTTTGACCATGCGGTCAAAAACTAGCTGCTTTTGCGGCCTTTTTCAGCTATCC
CTCGCTTGAGGACTCGTGAA

Product: NADPH:ferredoxin reductase

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MNTTSAFNTAGARPLQFPIPANVYAETVVSVKHYTDRLFSFRITRPQSLRFRSGEFVMIGLPNAEKPVFRAYSVASPAWD
EELEFFSIKVPDGPLTSELQKIQVGDTVIMRQKSTGTLVVDALTPAKRLFMISTGTGIAPFASLLRDPDTYEKFDQLILT
HTCRDNAELTYGQELVAALESDPLIGELTTGRVTLYNSTTREESARMGRITALIGSGKFYADLGIDKLNPETDRIMICGS
MHMLKDVKELAESLGFQEGSLSHPATFVVERAFVG

Sequences:

>Translated_275_residues
MNTTSAFNTAGARPLQFPIPANVYAETVVSVKHYTDRLFSFRITRPQSLRFRSGEFVMIGLPNAEKPVFRAYSVASPAWD
EELEFFSIKVPDGPLTSELQKIQVGDTVIMRQKSTGTLVVDALTPAKRLFMISTGTGIAPFASLLRDPDTYEKFDQLILT
HTCRDNAELTYGQELVAALESDPLIGELTTGRVTLYNSTTREESARMGRITALIGSGKFYADLGIDKLNPETDRIMICGS
MHMLKDVKELAESLGFQEGSLSHPATFVVERAFVG
>Mature_275_residues
MNTTSAFNTAGARPLQFPIPANVYAETVVSVKHYTDRLFSFRITRPQSLRFRSGEFVMIGLPNAEKPVFRAYSVASPAWD
EELEFFSIKVPDGPLTSELQKIQVGDTVIMRQKSTGTLVVDALTPAKRLFMISTGTGIAPFASLLRDPDTYEKFDQLILT
HTCRDNAELTYGQELVAALESDPLIGELTTGRVTLYNSTTREESARMGRITALIGSGKFYADLGIDKLNPETDRIMICGS
MHMLKDVKELAESLGFQEGSLSHPATFVVERAFVG

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=228, Percent_Identity=33.7719298245614, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 30370; Mature: 30370

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTSAFNTAGARPLQFPIPANVYAETVVSVKHYTDRLFSFRITRPQSLRFRSGEFVMIG
CCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEEEE
LPNAEKPVFRAYSVASPAWDEELEFFSIKVPDGPLTSELQKIQVGDTVIMRQKSTGTLVV
CCCCCCCHHHEEECCCCCCCCCCEEEEEECCCCCCHHHHHHEECCCEEEEEECCCCCEEE
DALTPAKRLFMISTGTGIAPFASLLRDPDTYEKFDQLILTHTCRDNAELTYGQELVAALE
EECCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHC
SDPLIGELTTGRVTLYNSTTREESARMGRITALIGSGKFYADLGIDKLNPETDRIMICGS
CCCCEEEECCCEEEEEECCCHHHHHHHCEEEEEEECCEEEEECCCCCCCCCCCEEEEECC
MHMLKDVKELAESLGFQEGSLSHPATFVVERAFVG
HHHHHHHHHHHHHCCCCCCCCCCCHHHEEEHHHCC
>Mature Secondary Structure
MNTTSAFNTAGARPLQFPIPANVYAETVVSVKHYTDRLFSFRITRPQSLRFRSGEFVMIG
CCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEEEE
LPNAEKPVFRAYSVASPAWDEELEFFSIKVPDGPLTSELQKIQVGDTVIMRQKSTGTLVV
CCCCCCCHHHEEECCCCCCCCCCEEEEEECCCCCCHHHHHHEECCCEEEEEECCCCCEEE
DALTPAKRLFMISTGTGIAPFASLLRDPDTYEKFDQLILTHTCRDNAELTYGQELVAALE
EECCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHC
SDPLIGELTTGRVTLYNSTTREESARMGRITALIGSGKFYADLGIDKLNPETDRIMICGS
CCCCEEEECCCEEEEEECCCHHHHHHHCEEEEEEECCEEEEECCCCCCCCCCCEEEEECC
MHMLKDVKELAESLGFQEGSLSHPATFVVERAFVG
HHHHHHHHHHHHHCCCCCCCCCCCHHHEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]