| Definition | Mesorhizobium loti MAFF303099 chromosome, complete genome. |
|---|---|
| Accession | NC_002678 |
| Length | 7,036,071 |
Click here to switch to the map view.
The map label for this gene is kduD [H]
Identifier: 13473975
GI number: 13473975
Start: 3762960
End: 3763724
Strand: Direct
Name: kduD [H]
Synonym: mlr4741
Alternate gene names: 13473975
Gene position: 3762960-3763724 (Clockwise)
Preceding gene: 13473974
Following gene: 13473976
Centisome position: 53.48
GC content: 67.19
Gene sequence:
>765_bases ATGCCATCGGCGGATTTTGCCGACCTCAAGGGCGCCTCGGTGCTGATCACCGGCGGCGGTTCCGGGATCGGCGCGGCGCT GACCGAGGGGTTTGTGCGCCAGGGTGCCAATGTCGCCTTCATCGACATCGCCGAGGGTCCGAGCACGCTGCTTGCCGACC GCATCGAGAAGGAATTCGGCCGGCGGCCGCTCTACCTCAAGACCGATCTGCGCGACATCGAGGCGCTGCGCGCCTCGGCG GCCAGGGCGGCGGAGGCGCATGGCGATGTCACGGTGCTGATCAACAATGCCGCCTGGGACGAGCGCCACGCCGTCGAGGA CGTGACGGTGGAGTTCTGGGACAACAACCAGGCGATCAACCTCAGGCCGCATTTCTTCACCGCGCAGGCGGTGGCGCCGG GCATGAAGCGGGCCGGCGGCGGCTCGATCATCAACTTCACCTCGACATCCTACCTCATCAACCATCCCGACATGCCGGCC TACACCGCCGCCAAGGCGGGCATCCTCGGCCTCACCAAGGGGCTCGCCGGCAAGCTCGGGCCGGACCGCATCCGCGTCAA CGCCGTCGCGCCCGGCTGGGTGATCACCGAACGGCAGCAGGAACGCTGGGTGACCGAAGGAGCGCTAGCAGCCCATGTCG CCAAGCAGTGCATCAAGGAGGTCATGCGCCCGGACGACATGGTCGGCACGGTGCTGTTCCTGGCCTCGGATGCCTCGCGC ATGCTGACCGCGCAGATGCTGATCGTCGACGGAGGTTTTCTGTGA
Upstream 100 bases:
>100_bases GGACGCGCAAAGGACGCTGTAGTAATTTACATTTTGCGCATGATCCCTTTCCGAAAATCGGATCGATTTTCGGGGTCATG CGCTGGGAGAGTAGAATATG
Downstream 100 bases:
>100_bases GCCCAGAATTTGCCGGCAACGCTCCGGCGGTAGCCGCACTCGATTGGGGCACGACCCGGCTCCGCGCATGGCTGATCGAC GGCAGCGGCAAGCTGCTTGC
Product: short chain dehydrogenase/reductase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MPSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFGRRPLYLKTDLRDIEALRASA ARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAINLRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPA YTAAKAGILGLTKGLAGKLGPDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASR MLTAQMLIVDGGFL
Sequences:
>Translated_254_residues MPSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFGRRPLYLKTDLRDIEALRASA ARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAINLRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPA YTAAKAGILGLTKGLAGKLGPDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASR MLTAQMLIVDGGFL >Mature_253_residues PSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFGRRPLYLKTDLRDIEALRASAA RAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAINLRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPAY TAAKAGILGLTKGLAGKLGPDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASRM LTAQMLIVDGGFL
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=173, Percent_Identity=33.5260115606936, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=32.520325203252, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=29.6747967479675, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=26.8, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI126723750, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=29.6, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=28.3505154639175, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI4504505, Length=186, Percent_Identity=30.6451612903226, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI126723191, Length=110, Percent_Identity=35.4545454545455, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI302344755, Length=108, Percent_Identity=35.1851851851852, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=26.7782426778243, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=26.7441860465116, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=32.1285140562249, Blast_Score=124, Evalue=4e-30, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=28.6852589641434, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=32.6693227091633, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=30.2681992337165, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.9212598425197, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=31.6, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=28.0769230769231, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=27.2357723577236, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.4552845528455, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=29.3650793650794, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789057, Length=250, Percent_Identity=26, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1787526, Length=246, Percent_Identity=26.0162601626016, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=31.3725490196078, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17561402, Length=270, Percent_Identity=30, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=28.75, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=27.6679841897233, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=28.2352941176471, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=26.2295081967213, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560676, Length=163, Percent_Identity=25.7668711656442, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.9693486590038, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203115, Length=224, Percent_Identity=25.4464285714286, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17544670, Length=283, Percent_Identity=26.1484098939929, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=30.7086614173228, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=29.3650793650794, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=26.953125, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=31.2, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=26.8, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=25.4032258064516, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=24.4979919678715, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI281364892, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI21358495, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=27.979274611399, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 27098; Mature: 26967
Theoretical pI: Translated: 6.03; Mature: 6.03
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFG CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHC RRPLYLKTDLRDIEALRASAARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAIN CCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCEEEEEEECCCCEEE LRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPAYTAAKAGILGLTKGLAGKLG ECCCEEEHHHHCCCHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHCHHHHHHHHCCCCC PDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASR CCEEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCHHH MLTAQMLIVDGGFL HHEEEEEEECCCCC >Mature Secondary Structure PSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFG CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHC RRPLYLKTDLRDIEALRASAARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAIN CCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCEEEEEEECCCCEEE LRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPAYTAAKAGILGLTKGLAGKLG ECCCEEEHHHHCCCHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHCHHHHHHHHCCCCC PDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASR CCEEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCHHH MLTAQMLIVDGGFL HHEEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 2836407; 1766386 [H]