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The map label for this gene is lldD [H]

Identifier: 13473966

GI number: 13473966

Start: 3753990

End: 3755048

Strand: Reverse

Name: lldD [H]

Synonym: mll4732

Alternate gene names: 13473966

Gene position: 3755048-3753990 (Counterclockwise)

Preceding gene: 13473967

Following gene: 13473962

Centisome position: 53.37

GC content: 61.95

Gene sequence:

>1059_bases
ATGCCACTTGACATCGAAACCCGGTTTCTCGGCTTGGCGGATTTTGAACCGGCTGCGCGAGAGGTGTTGCCGCATGCGGT
CTACGAGTTCATTGCCGGGGGTGCTGGCGACGAAATCACCAAGCGTGACAATGAAGCGGCATTCGACCGCATCAGGTTGA
GGCAGCGTGTGCTGCGCGATGTCACAAGACTTGATACCGCGATCACACTCTTTGGGCAAAGGCTGACGCATCCGATCATC
CTGGCCCCAATAGCATACCAGCGACTGGCGCATCCGGAAGGCGAGGTGGCCACGGCGCGCGGCGCCGGAGTGGCGGAAGC
GGTGTTCATTCTGGGTACTACGGCGACGGCGGCGATCGAGGATTGCGTGGCGGAGAGCCAGTCTCCTGTGTGGTTCCTGC
TTTATTGGCAAAGCGACCGCGGTTTCAATGGCGAACTCGTATCGCGCATGGCGGCACTGGGCGCAAAGGCGATCAGCGTA
ACGGTCGACCTGCCAACGCCAGGCGATCGCCGTAGGCAATTCCGGGCAGGCTTCAAAATTCCCGACAGCCTCGCAACGCC
GTACTTCAAGGACCGGAACACCGGCGTGCTCAAAGTTGGCACTGCGCAAAAGCGGGCCATGCCGACCTGGGCGGATATTG
CCTGGCTGCGTTCGCTGACAACCCTGCCGCTTATCCTGAAGGGTATCCTCGATCCTGACGATGCCGAGCAAGCCATCGGA
ACTGGTGCAGATGCTATAGTCGTCTCGAACCACGGTTCGCGTAACCTCGACACACTGCCGGCAGCCATCGACGCCCTGCC
CGCCATCGCGGAGCGGGTGGCCGGCCGGATCCCCATCATCCTCGATGGCGGCGTTAGGCGTGGCACCGACGTTTTGAAGG
CGATTGCGCTAGGGGCAAGCGCTGTCATGATTGGCCGCCCTTATGTCTACGCCCTAGCAACGGCTGGTGCCGAGGGCGTA
GCCCACTGCGTCAACCTGCTTCGCCGTGACTTCGAGATGGCAATGGCGCTAACCGGCCGGGCGCGCCTCGGCGAAATCGA
CCGGTCGGTAATCTGGTGA

Upstream 100 bases:

>100_bases
CTTCGCGCCGGACCACCGCCTTGCGGTCAGCGGAGATTTGCACGAATGTTGCCTGTGGAATAGCCGACTTTCTTGAGATA
CCGATCGGACGGACTGGTCC

Downstream 100 bases:

>100_bases
AGCCTGGACCTATTCCTCGGCAAAGTTCAGGATTCACCATGATGGCCTTGCGGTCCAACAATTGAGGCAGAAGGGGTTGG
CCATTCACGCAACCTCTGAA

Product: glycolate oxidase, (S)-2-hydroxy-acid oxidase, peroxisomal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MPLDIETRFLGLADFEPAAREVLPHAVYEFIAGGAGDEITKRDNEAAFDRIRLRQRVLRDVTRLDTAITLFGQRLTHPII
LAPIAYQRLAHPEGEVATARGAGVAEAVFILGTTATAAIEDCVAESQSPVWFLLYWQSDRGFNGELVSRMAALGAKAISV
TVDLPTPGDRRRQFRAGFKIPDSLATPYFKDRNTGVLKVGTAQKRAMPTWADIAWLRSLTTLPLILKGILDPDDAEQAIG
TGADAIVVSNHGSRNLDTLPAAIDALPAIAERVAGRIPIILDGGVRRGTDVLKAIALGASAVMIGRPYVYALATAGAEGV
AHCVNLLRRDFEMAMALTGRARLGEIDRSVIW

Sequences:

>Translated_352_residues
MPLDIETRFLGLADFEPAAREVLPHAVYEFIAGGAGDEITKRDNEAAFDRIRLRQRVLRDVTRLDTAITLFGQRLTHPII
LAPIAYQRLAHPEGEVATARGAGVAEAVFILGTTATAAIEDCVAESQSPVWFLLYWQSDRGFNGELVSRMAALGAKAISV
TVDLPTPGDRRRQFRAGFKIPDSLATPYFKDRNTGVLKVGTAQKRAMPTWADIAWLRSLTTLPLILKGILDPDDAEQAIG
TGADAIVVSNHGSRNLDTLPAAIDALPAIAERVAGRIPIILDGGVRRGTDVLKAIALGASAVMIGRPYVYALATAGAEGV
AHCVNLLRRDFEMAMALTGRARLGEIDRSVIW
>Mature_351_residues
PLDIETRFLGLADFEPAAREVLPHAVYEFIAGGAGDEITKRDNEAAFDRIRLRQRVLRDVTRLDTAITLFGQRLTHPIIL
APIAYQRLAHPEGEVATARGAGVAEAVFILGTTATAAIEDCVAESQSPVWFLLYWQSDRGFNGELVSRMAALGAKAISVT
VDLPTPGDRRRQFRAGFKIPDSLATPYFKDRNTGVLKVGTAQKRAMPTWADIAWLRSLTTLPLILKGILDPDDAEQAIGT
GADAIVVSNHGSRNLDTLPAAIDALPAIAERVAGRIPIILDGGVRRGTDVLKAIALGASAVMIGRPYVYALATAGAEGVA
HCVNLLRRDFEMAMALTGRARLGEIDRSVIW

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=354, Percent_Identity=42.090395480226, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI7705393, Length=354, Percent_Identity=42.090395480226, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI11068137, Length=358, Percent_Identity=41.340782122905, Blast_Score=271, Evalue=9e-73,
Organism=Escherichia coli, GI1790033, Length=364, Percent_Identity=36.8131868131868, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI193208036, Length=355, Percent_Identity=34.6478873239437, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI32566217, Length=270, Percent_Identity=31.4814814814815, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323587, Length=363, Percent_Identity=34.1597796143251, Blast_Score=202, Evalue=9e-53,
Organism=Drosophila melanogaster, GI78707188, Length=350, Percent_Identity=40.2857142857143, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI281363140, Length=350, Percent_Identity=40.2857142857143, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI78707190, Length=350, Percent_Identity=40.2857142857143, Blast_Score=252, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 37969; Mature: 37838

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDIETRFLGLADFEPAAREVLPHAVYEFIAGGAGDEITKRDNEAAFDRIRLRQRVLRD
CCCCCCHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
VTRLDTAITLFGQRLTHPIILAPIAYQRLAHPEGEVATARGAGVAEAVFILGTTATAAIE
HHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCEEECCCCCHHHHHHEEECCHHHHHH
DCVAESQSPVWFLLYWQSDRGFNGELVSRMAALGAKAISVTVDLPTPGDRRRQFRAGFKI
HHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHCCCCC
PDSLATPYFKDRNTGVLKVGTAQKRAMPTWADIAWLRSLTTLPLILKGILDPDDAEQAIG
CHHHCCCCCCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
TGADAIVVSNHGSRNLDTLPAAIDALPAIAERVAGRIPIILDGGVRRGTDVLKAIALGAS
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCC
AVMIGRPYVYALATAGAEGVAHCVNLLRRDFEMAMALTGRARLGEIDRSVIW
EEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
PLDIETRFLGLADFEPAAREVLPHAVYEFIAGGAGDEITKRDNEAAFDRIRLRQRVLRD
CCCCCHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
VTRLDTAITLFGQRLTHPIILAPIAYQRLAHPEGEVATARGAGVAEAVFILGTTATAAIE
HHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCEEECCCCCHHHHHHEEECCHHHHHH
DCVAESQSPVWFLLYWQSDRGFNGELVSRMAALGAKAISVTVDLPTPGDRRRQFRAGFKI
HHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHCCCCC
PDSLATPYFKDRNTGVLKVGTAQKRAMPTWADIAWLRSLTTLPLILKGILDPDDAEQAIG
CHHHCCCCCCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
TGADAIVVSNHGSRNLDTLPAAIDALPAIAERVAGRIPIILDGGVRRGTDVLKAIALGAS
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCC
AVMIGRPYVYALATAGAEGVAHCVNLLRRDFEMAMALTGRARLGEIDRSVIW
EEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA