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The map label for this gene is uppP

Identifier: 13473889

GI number: 13473889

Start: 3672868

End: 3673674

Strand: Reverse

Name: uppP

Synonym: mll4634

Alternate gene names: 13473889

Gene position: 3673674-3672868 (Counterclockwise)

Preceding gene: 13473901

Following gene: 13473886

Centisome position: 52.21

GC content: 63.07

Gene sequence:

>807_bases
ATGGAAAGCCAGACCATCGTCGAAGCCCTGCTGCTCGGCCTGCTGGAGGGCCTGACCGAGTTCATACCGGTGTCCTCGAC
CGGCCATATCCTGCTCGCCGGCCATTTCCTCGGCTTCAATTCGACGGGCAAGGCCTTCGAGATCCTGATCCAGCTCGGCG
CCATCCTGGCGATCCTGAGCGTCTACTTCCGCCGCTTGTGGCAGATGCTGCTCGACCTGCCGCATGACCGGCTGACGCGG
CATTTCGTCATCGGCATCCTGATTGCCTTTCTGCCGGCTGCGATCATCGGCGCGCTGGCGCATGATTTCATCAAGACGGT
GCTGTTCGAATCGCCGAGGCTGATCTGCACCATGCTGATCATCGGCGGTGTTATCCTACTGGCGGTCGACCGCATGAACC
TGAAGCCGGTCTATCGCGATGTCGAGCGCTTCCCAACCAGGCTCTACCTGCAGATCGGCCTGTTCCAGTGCCTGTCGCTG
ATCCCCGGCACGTCGCGCTCGGGTTCGACCATCGTCGGCGCGCTGCTTCTGGGCGTCGACAAGCGGGCGGCGGCGGAATT
CTCCTTCTTCCTGGCGATCCCGACCATGGTCGGCGCCTTCGCCTTCGACCTGTTCAAGAACCGCAACGTGCTGACCTCGG
CCGACCTGCCGATCATCGCCATCGGCTTCGTCGCCGCCTTCGTCACCGCGCTGTTCGTGGTGCGCTACCTGCTCGATTAC
GTCTCGCGCAACGGCTACTCGCTGTTCGGCTGGTGGCGGCTGGTGGTGGGTATTGTCGGGCTGGTGGCGTTGATGATCTG
GGGGTGA

Upstream 100 bases:

>100_bases
CCCGGTTAGCGGGCCGTCAGGGTGTTGCGACCTATAGGGGGACTTCAACGCCATGACAAGCAAGCCGTTCAGTTAGCCGT
CGCGCAAAGCCGAGGTAGCC

Downstream 100 bases:

>100_bases
GCGTAGGTCGTTCCCTTACTGCGCCGCCGAGTTCCTTCGCTGACCCGCCGACGTCTCGCAGGTTCGCCTTCGGCAAAGCC
CTCTAATTCCGCCCATAAAA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MESQTIVEALLLGLLEGLTEFIPVSSTGHILLAGHFLGFNSTGKAFEILIQLGAILAILSVYFRRLWQMLLDLPHDRLTR
HFVIGILIAFLPAAIIGALAHDFIKTVLFESPRLICTMLIIGGVILLAVDRMNLKPVYRDVERFPTRLYLQIGLFQCLSL
IPGTSRSGSTIVGALLLGVDKRAAAEFSFFLAIPTMVGAFAFDLFKNRNVLTSADLPIIAIGFVAAFVTALFVVRYLLDY
VSRNGYSLFGWWRLVVGIVGLVALMIWG

Sequences:

>Translated_268_residues
MESQTIVEALLLGLLEGLTEFIPVSSTGHILLAGHFLGFNSTGKAFEILIQLGAILAILSVYFRRLWQMLLDLPHDRLTR
HFVIGILIAFLPAAIIGALAHDFIKTVLFESPRLICTMLIIGGVILLAVDRMNLKPVYRDVERFPTRLYLQIGLFQCLSL
IPGTSRSGSTIVGALLLGVDKRAAAEFSFFLAIPTMVGAFAFDLFKNRNVLTSADLPIIAIGFVAAFVTALFVVRYLLDY
VSRNGYSLFGWWRLVVGIVGLVALMIWG
>Mature_268_residues
MESQTIVEALLLGLLEGLTEFIPVSSTGHILLAGHFLGFNSTGKAFEILIQLGAILAILSVYFRRLWQMLLDLPHDRLTR
HFVIGILIAFLPAAIIGALAHDFIKTVLFESPRLICTMLIIGGVILLAVDRMNLKPVYRDVERFPTRLYLQIGLFQCLSL
IPGTSRSGSTIVGALLLGVDKRAAAEFSFFLAIPTMVGAFAFDLFKNRNVLTSADLPIIAIGFVAAFVTALFVVRYLLDY
VSRNGYSLFGWWRLVVGIVGLVALMIWG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=264, Percent_Identity=41.6666666666667, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_RHILO (Q98DM7)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105457.1
- GeneID:   1228118
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4634
- NMPDR:   fig|266835.1.peg.3561
- HOGENOM:   HBG391969
- OMA:   GIWMIFA
- ProtClustDB:   PRK00281
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29530; Mature: 29530

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x130d9678)-; HASH(0x11a8070c)-; HASH(0x13db72d4)-; HASH(0x13defb5c)-; HASH(0x12d2b458)-; HASH(0x13db6f80)-; HASH(0x1311de54)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQTIVEALLLGLLEGLTEFIPVSSTGHILLAGHFLGFNSTGKAFEILIQLGAILAILS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
VYFRRLWQMLLDLPHDRLTRHFVIGILIAFLPAAIIGALAHDFIKTVLFESPRLICTMLI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IGGVILLAVDRMNLKPVYRDVERFPTRLYLQIGLFQCLSLIPGTSRSGSTIVGALLLGVD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
KRAAAEFSFFLAIPTMVGAFAFDLFKNRNVLTSADLPIIAIGFVAAFVTALFVVRYLLDY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSRNGYSLFGWWRLVVGIVGLVALMIWG
HHCCCCHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MESQTIVEALLLGLLEGLTEFIPVSSTGHILLAGHFLGFNSTGKAFEILIQLGAILAILS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
VYFRRLWQMLLDLPHDRLTRHFVIGILIAFLPAAIIGALAHDFIKTVLFESPRLICTMLI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IGGVILLAVDRMNLKPVYRDVERFPTRLYLQIGLFQCLSLIPGTSRSGSTIVGALLLGVD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
KRAAAEFSFFLAIPTMVGAFAFDLFKNRNVLTSADLPIIAIGFVAAFVTALFVVRYLLDY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSRNGYSLFGWWRLVVGIVGLVALMIWG
HHCCCCHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968