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The map label for this gene is ilvA [H]

Identifier: 13473862

GI number: 13473862

Start: 3650167

End: 3651150

Strand: Reverse

Name: ilvA [H]

Synonym: mll4597

Alternate gene names: 13473862

Gene position: 3651150-3650167 (Counterclockwise)

Preceding gene: 13473863

Following gene: 13473857

Centisome position: 51.89

GC content: 67.68

Gene sequence:

>984_bases
ATGACCGCCACCACCCCTCCCGGCATCGCCGACATCCGTGCCGCCGCCGCCCGCCTCTCCGGCCTGATCGTCGAAACGCC
ATTGATCGAATCGGCCGAGCTGAACAAGCGCTTCGGCGGCCGTATCCTGTTCAAGCCGGAGACGTTGCAGCGCACCGGCT
CGTTCAAGTTCCGCGGCGCCTACAACAAGCTGTCGTCGCTGAGCGAGGAAGAGCGCAGCCGTGGCGTCGTCGCCTTCTCC
TCCGGCAATCATGCGCAAGGGGTTGCCGCTTCGGCCGCCATGTTCGGCGTCAAGGCGGTCATCGCCATGCCGGCGGACGC
GCCGGCGATGAAGATCGGCAATGTCCGCAAGATGGGCGCGGAGGTGGTGCCGTTCGACCGCTTTCGCGATGACCGCATGA
CCGTGGTTCGCCCCTATATCGACAAGGGCATGGTGCTGGTGCCGCCCTTCGACGATCCGGCCATCATTGCCGGGCAAGGC
ACGATCGGCCTTGAACTGATGCGGCAGGGCAGGGCGCTCGGCGTCAGCCTCGACACCGTCGTCATCCCCTGCGGGGGCGG
CGGCCTGTCGAGCGGCATTTCGGTGGCGGTCAAGGATGCCTCGCCGGGCACGGCGGTCTGGGCGGTAGAGCCCGAGCATT
TCGACGACACGCGCCGCTCGCTCGCCGCAGGCGCGCGGGTTTCGAACGAGCCCGGCCACAGCTCGATCTGCGACGCGATC
CTGACCGCCGAGCCGGGCGCCATCACCTTCGAAATCAACCGCAGGAACCTCACTGGGGCCATTGCCGTCTCCGACAAGGC
GACCGCACAGGCGATGCGCGATGCCATGGCCTATCTGAAGCTGGTGGTCGAGCCGGGCGGCTGCGTGGCGCTGGCGGCGC
TGTCGTCGGGCGAGATCGAACTGTCCGGCAAATGCGTCGCCGTGGTGCTGTCCGGCGGCAATGTCGATTTCGGCACCTAT
GCCGGGATCATGGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGCCACCGCCAACTTTGTAACGGTCACATTTTTTCAATGGTGCGCCATGTGCCTTTGCGGGCATCATGAGAAGAGACTG
CCTCTCTTGTTGGACCTCGC

Downstream 100 bases:

>100_bases
GCGCTTTGTCCTGTGCGCCATGCCTGCTATTGGCGCAGCCCGGCGGGCTGCCTCGGCCGCTCACAGCGGCCGGGCTGAGG
CGTCCGTTTGCGGTCAGTCC

Product: putative threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTATTPPGIADIRAAAARLSGLIVETPLIESAELNKRFGGRILFKPETLQRTGSFKFRGAYNKLSSLSEEERSRGVVAFS
SGNHAQGVAASAAMFGVKAVIAMPADAPAMKIGNVRKMGAEVVPFDRFRDDRMTVVRPYIDKGMVLVPPFDDPAIIAGQG
TIGLELMRQGRALGVSLDTVVIPCGGGGLSSGISVAVKDASPGTAVWAVEPEHFDDTRRSLAAGARVSNEPGHSSICDAI
LTAEPGAITFEINRRNLTGAIAVSDKATAQAMRDAMAYLKLVVEPGGCVALAALSSGEIELSGKCVAVVLSGGNVDFGTY
AGIMAAA

Sequences:

>Translated_327_residues
MTATTPPGIADIRAAAARLSGLIVETPLIESAELNKRFGGRILFKPETLQRTGSFKFRGAYNKLSSLSEEERSRGVVAFS
SGNHAQGVAASAAMFGVKAVIAMPADAPAMKIGNVRKMGAEVVPFDRFRDDRMTVVRPYIDKGMVLVPPFDDPAIIAGQG
TIGLELMRQGRALGVSLDTVVIPCGGGGLSSGISVAVKDASPGTAVWAVEPEHFDDTRRSLAAGARVSNEPGHSSICDAI
LTAEPGAITFEINRRNLTGAIAVSDKATAQAMRDAMAYLKLVVEPGGCVALAALSSGEIELSGKCVAVVLSGGNVDFGTY
AGIMAAA
>Mature_326_residues
TATTPPGIADIRAAAARLSGLIVETPLIESAELNKRFGGRILFKPETLQRTGSFKFRGAYNKLSSLSEEERSRGVVAFSS
GNHAQGVAASAAMFGVKAVIAMPADAPAMKIGNVRKMGAEVVPFDRFRDDRMTVVRPYIDKGMVLVPPFDDPAIIAGQGT
IGLELMRQGRALGVSLDTVVIPCGGGGLSSGISVAVKDASPGTAVWAVEPEHFDDTRRSLAAGARVSNEPGHSSICDAIL
TAEPGAITFEINRRNLTGAIAVSDKATAQAMRDAMAYLKLVVEPGGCVALAALSSGEIELSGKCVAVVLSGGNVDFGTYA
GIMAAA

Specific function: Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=324, Percent_Identity=33.641975308642, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1789505, Length=326, Percent_Identity=38.3435582822086, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1790207, Length=295, Percent_Identity=37.9661016949153, Blast_Score=156, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71991565, Length=313, Percent_Identity=33.2268370607029, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17508781, Length=329, Percent_Identity=27.9635258358663, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17537387, Length=308, Percent_Identity=34.4155844155844, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322631, Length=321, Percent_Identity=41.7445482866044, Blast_Score=229, Evalue=7e-61,
Organism=Saccharomyces cerevisiae, GI6320930, Length=303, Percent_Identity=31.3531353135314, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6319788, Length=291, Percent_Identity=25.085910652921, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355833, Length=308, Percent_Identity=34.4155844155844, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR001721
- InterPro:   IPR011820 [H]

Pfam domain/function: PF00291 PALP; PF00585 Thr_dehydrat_C [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 33863; Mature: 33732

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATTPPGIADIRAAAARLSGLIVETPLIESAELNKRFGGRILFKPETLQRTGSFKFRGA
CCCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHCCEEEECCHHHHHCCCEEEEEH
YNKLSSLSEEERSRGVVAFSSGNHAQGVAASAAMFGVKAVIAMPADAPAMKIGNVRKMGA
HHHHHHCCHHHHHCCEEEECCCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCHHHCCC
EVVPFDRFRDDRMTVVRPYIDKGMVLVPPFDDPAIIAGQGTIGLELMRQGRALGVSLDTV
CCCCHHHCCCCCEEEEEEHHCCCEEEECCCCCCEEEECCCCHHHHHHHCCCEEEEEEEEE
VIPCGGGGLSSGISVAVKDASPGTAVWAVEPEHFDDTRRSLAAGARVSNEPGHSSICDAI
EEECCCCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
LTAEPGAITFEINRRNLTGAIAVSDKATAQAMRDAMAYLKLVVEPGGCVALAALSSGEIE
HCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCCEE
LSGKCVAVVLSGGNVDFGTYAGIMAAA
ECCCEEEEEEECCCCCHHHHHHHEECC
>Mature Secondary Structure 
TATTPPGIADIRAAAARLSGLIVETPLIESAELNKRFGGRILFKPETLQRTGSFKFRGA
CCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHCCEEEECCHHHHHCCCEEEEEH
YNKLSSLSEEERSRGVVAFSSGNHAQGVAASAAMFGVKAVIAMPADAPAMKIGNVRKMGA
HHHHHHCCHHHHHCCEEEECCCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCHHHCCC
EVVPFDRFRDDRMTVVRPYIDKGMVLVPPFDDPAIIAGQGTIGLELMRQGRALGVSLDTV
CCCCHHHCCCCCEEEEEEHHCCCEEEECCCCCCEEEECCCCHHHHHHHCCCEEEEEEEEE
VIPCGGGGLSSGISVAVKDASPGTAVWAVEPEHFDDTRRSLAAGARVSNEPGHSSICDAI
EEECCCCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
LTAEPGAITFEINRRNLTGAIAVSDKATAQAMRDAMAYLKLVVEPGGCVALAALSSGEIE
HCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCCEE
LSGKCVAVVLSGGNVDFGTYAGIMAAA
ECCCEEEEEEECCCCCHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA