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The map label for this gene is yafC [H]

Identifier: 13473281

GI number: 13473281

Start: 3067780

End: 3068688

Strand: Reverse

Name: yafC [H]

Synonym: mll3827

Alternate gene names: 13473281

Gene position: 3068688-3067780 (Counterclockwise)

Preceding gene: 13473283

Following gene: 13473279

Centisome position: 43.61

GC content: 67.11

Gene sequence:

>909_bases
ATGGCCGACATCGACTGGAACTTGATCAAGAGCTTCGTCACGGTCGCGGAAACCGGCAGTCTGTCGGCCGCCGCGCGCAA
GCTGTCGGCCAGCCAGCCGACGCTTGGCCGTCATATCGGCGAGTTGGAGCAGGCGCTCGGTGTGACGCTGTTCAGGCGTG
GGCGGAGCGGCTATGCGCTGACGGAAGCCGGCGCCACGCTGTTCGAGCGCGGCAAGGCGGTCAGCGAGCAGGCGAGTGCG
TTTTCACGCCTGGCACTGGGCTCGGTCGAGGCGATCGAAGGCACGGTGCGCATCGCCGCCAGCGAAGTGGTGGCGGCTTA
TGTGCTGCCCGACATGACCGCACGGCTCGGCGTCGAGGAACCCGGCATCGAGGTGGAGATCGTTGCCTCGAACCAGGTCG
AGAACCTGCTGCGCCGGGACGCCGACATCGCCATCCGCATGGTCAAGCCGGCGCAGAACGAACTGGTGGCACGCAAGGTC
TGCGATATCGAGCTCTGCGCCTGCGCGGCCATTTCCTATCTCGACCGGCGCGGCCGCCCGGTCGGGCCGGCCGACCTCGT
CGACCACCCCTTGATCGGCTTCGATCGCAGCGACGAGATGATCCGGGGCTTCACGCAATTCGGTATCCCTGTCACCCGAA
GCAGTTTCCGCTTCAGGGCCGATAATCAGGTCGTGCTGTGGGAGGCGGTGAGGGCGGGAAACGGTATTGGCCTTGGCCAG
GAGCCGCTGGCCGATCGCGACCCGCTGGTGGAGAAGGTGCTGCCCGGCCTGCCGCTGCCAAGCCTGCCGGTATGGCTGGC
CATGCATCGCGATGTGCGCAGCAGCGTGCGCATCCGCCGCGTGGCGGATTTTCTCCACGAGGAGCTGAAGCGCTATTCGG
CGGGCACGGGGGCGAATTCGGCGCGGTGA

Upstream 100 bases:

>100_bases
TTGGTCGTTGCAGTCTGTATCGGTGTTTGCTGGGCGAATATGATTGCCTCACCGATGAATTGAAATTGACCATGGATGCA
GTTTTGATATTCATTATTGA

Downstream 100 bases:

>100_bases
GCGAGGCCCGCCATCAGCAGGACGACGATCAGCAGCACCGACATGGCGATGAAGATCGGCCCGAAGCTGGAATGCTCGGC
GACGAAACCGATCGCCGACG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MADIDWNLIKSFVTVAETGSLSAAARKLSASQPTLGRHIGELEQALGVTLFRRGRSGYALTEAGATLFERGKAVSEQASA
FSRLALGSVEAIEGTVRIAASEVVAAYVLPDMTARLGVEEPGIEVEIVASNQVENLLRRDADIAIRMVKPAQNELVARKV
CDIELCACAAISYLDRRGRPVGPADLVDHPLIGFDRSDEMIRGFTQFGIPVTRSSFRFRADNQVVLWEAVRAGNGIGLGQ
EPLADRDPLVEKVLPGLPLPSLPVWLAMHRDVRSSVRIRRVADFLHEELKRYSAGTGANSAR

Sequences:

>Translated_302_residues
MADIDWNLIKSFVTVAETGSLSAAARKLSASQPTLGRHIGELEQALGVTLFRRGRSGYALTEAGATLFERGKAVSEQASA
FSRLALGSVEAIEGTVRIAASEVVAAYVLPDMTARLGVEEPGIEVEIVASNQVENLLRRDADIAIRMVKPAQNELVARKV
CDIELCACAAISYLDRRGRPVGPADLVDHPLIGFDRSDEMIRGFTQFGIPVTRSSFRFRADNQVVLWEAVRAGNGIGLGQ
EPLADRDPLVEKVLPGLPLPSLPVWLAMHRDVRSSVRIRRVADFLHEELKRYSAGTGANSAR
>Mature_301_residues
ADIDWNLIKSFVTVAETGSLSAAARKLSASQPTLGRHIGELEQALGVTLFRRGRSGYALTEAGATLFERGKAVSEQASAF
SRLALGSVEAIEGTVRIAASEVVAAYVLPDMTARLGVEEPGIEVEIVASNQVENLLRRDADIAIRMVKPAQNELVARKVC
DIELCACAAISYLDRRGRPVGPADLVDHPLIGFDRSDEMIRGFTQFGIPVTRSSFRFRADNQVVLWEAVRAGNGIGLGQE
PLADRDPLVEKVLPGLPLPSLPVWLAMHRDVRSSVRIRRVADFLHEELKRYSAGTGANSAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=28, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789639, Length=238, Percent_Identity=31.0924369747899, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693193, Length=187, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787128, Length=189, Percent_Identity=26.984126984127, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787601, Length=168, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788481, Length=285, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=134, Percent_Identity=30.5970149253731, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32769; Mature: 32638

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIDWNLIKSFVTVAETGSLSAAARKLSASQPTLGRHIGELEQALGVTLFRRGRSGYAL
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
TEAGATLFERGKAVSEQASAFSRLALGSVEAIEGTVRIAASEVVAAYVLPDMTARLGVEE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGIEVEIVASNQVENLLRRDADIAIRMVKPAQNELVARKVCDIELCACAAISYLDRRGRP
CCCEEEEEECHHHHHHHHCCCHHEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
VGPADLVDHPLIGFDRSDEMIRGFTQFGIPVTRSSFRFRADNQVVLWEAVRAGNGIGLGQ
CCCHHHHCCCCCCCCCCHHHHHHHHHHCCCEECCCEEEECCCEEEEEEHHHCCCCCCCCC
EPLADRDPLVEKVLPGLPLPSLPVWLAMHRDVRSSVRIRRVADFLHEELKRYSAGTGANS
CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AR
CC
>Mature Secondary Structure 
ADIDWNLIKSFVTVAETGSLSAAARKLSASQPTLGRHIGELEQALGVTLFRRGRSGYAL
CCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
TEAGATLFERGKAVSEQASAFSRLALGSVEAIEGTVRIAASEVVAAYVLPDMTARLGVEE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGIEVEIVASNQVENLLRRDADIAIRMVKPAQNELVARKVCDIELCACAAISYLDRRGRP
CCCEEEEEECHHHHHHHHCCCHHEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
VGPADLVDHPLIGFDRSDEMIRGFTQFGIPVTRSSFRFRADNQVVLWEAVRAGNGIGLGQ
CCCHHHHCCCCCCCCCCHHHHHHHHHHCCCEECCCEEEECCCEEEEEEHHHCCCCCCCCC
EPLADRDPLVEKVLPGLPLPSLPVWLAMHRDVRSSVRIRRVADFLHEELKRYSAGTGANS
CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]