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The map label for this gene is blh [H]

Identifier: 13473216

GI number: 13473216

Start: 3013681

End: 3014541

Strand: Reverse

Name: blh [H]

Synonym: mll3743

Alternate gene names: 13473216

Gene position: 3014541-3013681 (Counterclockwise)

Preceding gene: 13473217

Following gene: 13473213

Centisome position: 42.84

GC content: 63.07

Gene sequence:

>861_bases
TTGGCAAGACCTGAGGTCAGGGGCTTTTACGACAAGCCGACCGGAGCCATTCAATATGTCGTCACCGATCCGGCGACAAG
GCGCTGCGCCATCATCGATCCGATCCTCGACTTCGATGAGAAATCCGGTGCGACGGGAACGAAGAGCGCGGATGCCCTGC
TCGATTTCGTGGGGGAGAACGGACTGGAGCCCGAGTGGATCCTCGACACCCACCCGCATGCCGATCATTTCTCGGCCGCG
CACTATCTGAAACAGAAGACCGGGGCGCCGACGGCGATCGGTAACAGAATCGTCGACGTCCAGAACCTGTGGAAGGCGAT
CTATAACTGGCCGGATTTTCCCGCCGACGGTTCGCAGTGGGACAGGCTGTTCAGGGAAGGTGAGACCTTCCTGATTGGGA
CCCTTCCGGTCAAGGTGCTGTTCTCACCCGGACATACACTGGCTTCGATCACCTATGTGATCGGCGACGCCGCCTTCGTG
CACGACACGCTGTTCATGCCCGACAGCGGTACGGCGCGGGCGGATTTCCCCGGCGGGAGTGCCGCGCGGCTGTGGCGCTC
GATCCAGGAGATACTGGCGCTGCCCGATGAGACGCGCGTCTTCGTCGGCCATGACTATCAGGCCGGCGGCCGCGAGCCCT
TGTGGGAGAGCACGGTGGCCGCGCAGAGGGCCAGCAATATCCATCTCGCTGCCGCGCACAGCGAGGCCGAGTTCGTGGCG
CTGCGCGAGGCACGCGACAAGACATTGCCGATGCCGCGGCTGATCCTGCACGCGCTGCAGGTCAACATGAATGGCGGCCG
GCTGCCGGAACCGGAAGCCAATGGCCGGCGGTATCTGAAATTTCCGCTGGATGGGCTTTGA

Upstream 100 bases:

>100_bases
TGACTGGCCTGCCTCGGTGGACAACCATGCTCCTGTTGGAGCTTGGCGGAGAAAATCGTTCCTGTCGGCTGGGTTGGGGG
AGTTCGGCTTGGAATTGGCT

Downstream 100 bases:

>100_bases
GGCGATCGCCGCGACACCCCGCGTACGAAAAAGGCGGCGCCAGTATCCTGGCGCCGCCTTGATGTTTTGTCGCCGAAGCT
GGCTTAAGCCGCCGGCTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MARPEVRGFYDKPTGAIQYVVTDPATRRCAIIDPILDFDEKSGATGTKSADALLDFVGENGLEPEWILDTHPHADHFSAA
HYLKQKTGAPTAIGNRIVDVQNLWKAIYNWPDFPADGSQWDRLFREGETFLIGTLPVKVLFSPGHTLASITYVIGDAAFV
HDTLFMPDSGTARADFPGGSAARLWRSIQEILALPDETRVFVGHDYQAGGREPLWESTVAAQRASNIHLAAAHSEAEFVA
LREARDKTLPMPRLILHALQVNMNGGRLPEPEANGRRYLKFPLDGL

Sequences:

>Translated_286_residues
MARPEVRGFYDKPTGAIQYVVTDPATRRCAIIDPILDFDEKSGATGTKSADALLDFVGENGLEPEWILDTHPHADHFSAA
HYLKQKTGAPTAIGNRIVDVQNLWKAIYNWPDFPADGSQWDRLFREGETFLIGTLPVKVLFSPGHTLASITYVIGDAAFV
HDTLFMPDSGTARADFPGGSAARLWRSIQEILALPDETRVFVGHDYQAGGREPLWESTVAAQRASNIHLAAAHSEAEFVA
LREARDKTLPMPRLILHALQVNMNGGRLPEPEANGRRYLKFPLDGL
>Mature_285_residues
ARPEVRGFYDKPTGAIQYVVTDPATRRCAIIDPILDFDEKSGATGTKSADALLDFVGENGLEPEWILDTHPHADHFSAAH
YLKQKTGAPTAIGNRIVDVQNLWKAIYNWPDFPADGSQWDRLFREGETFLIGTLPVKVLFSPGHTLASITYVIGDAAFVH
DTLFMPDSGTARADFPGGSAARLWRSIQEILALPDETRVFVGHDYQAGGREPLWESTVAAQRASNIHLAAAHSEAEFVAL
REARDKTLPMPRLILHALQVNMNGGRLPEPEANGRRYLKFPLDGL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=264, Percent_Identity=27.6515151515151, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=267, Percent_Identity=27.7153558052434, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221330176, Length=263, Percent_Identity=28.1368821292776, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31554; Mature: 31423

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPEVRGFYDKPTGAIQYVVTDPATRRCAIIDPILDFDEKSGATGTKSADALLDFVGEN
CCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECHHHCCCCCCCCCCCCHHHHHHHHHCCC
GLEPEWILDTHPHADHFSAAHYLKQKTGAPTAIGNRIVDVQNLWKAIYNWPDFPADGSQW
CCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHCCEEECHHHHHHHHHCCCCCCCCCHHH
DRLFREGETFLIGTLPVKVLFSPGHTLASITYVIGDAAFVHDTLFMPDSGTARADFPGGS
HHHHHCCCEEEEEECEEEEEECCCCHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCCCCH
AARLWRSIQEILALPDETRVFVGHDYQAGGREPLWESTVAAQRASNIHLAAAHSEAEFVA
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHH
LREARDKTLPMPRLILHALQVNMNGGRLPEPEANGRRYLKFPLDGL
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
ARPEVRGFYDKPTGAIQYVVTDPATRRCAIIDPILDFDEKSGATGTKSADALLDFVGEN
CCCCCCCCCCCCCCEEEEEEECCCCCEEEEECHHHCCCCCCCCCCCCHHHHHHHHHCCC
GLEPEWILDTHPHADHFSAAHYLKQKTGAPTAIGNRIVDVQNLWKAIYNWPDFPADGSQW
CCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHCCEEECHHHHHHHHHCCCCCCCCCHHH
DRLFREGETFLIGTLPVKVLFSPGHTLASITYVIGDAAFVHDTLFMPDSGTARADFPGGS
HHHHHCCCEEEEEECEEEEEECCCCHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCCCCH
AARLWRSIQEILALPDETRVFVGHDYQAGGREPLWESTVAAQRASNIHLAAAHSEAEFVA
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHH
LREARDKTLPMPRLILHALQVNMNGGRLPEPEANGRRYLKFPLDGL
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]