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The map label for this gene is gacS [H]

Identifier: 13473203

GI number: 13473203

Start: 3000136

End: 3004311

Strand: Reverse

Name: gacS [H]

Synonym: mll3725

Alternate gene names: 13473203

Gene position: 3004311-3000136 (Counterclockwise)

Preceding gene: 13473205

Following gene: 13473202

Centisome position: 42.7

GC content: 63.98

Gene sequence:

>4176_bases
ATGGCGGAAGCGGACGAAGCAATCGGCGCGCGCGGCAAGCGTGGGCCCGACAAGCCGGTGCATCGCGGCGACGCACCGCC
ATGCGCGGACAGGGATTCGCCCGACGCGCTTCGCCAACTGCTCGAGGCGGGCTCGGACTGGATCTGGGAGACCGACGCCG
AACTGCGATTCTCCTGGCTTTCACCCACGTACCAGGCGGCCACCGGTATCGATCCGGCTGATGTGCTGGGCCGGTTCCGC
TTCGATTTCCTCAACCAGGACCTGAAAGGCAGCCGCAGCGCGGCGGCGCATCTGGAGGATTTGCAGGCACGCCGGCCGTT
CCGCGACTTCGTCTACGAACTGAAGGCGGGCGGCGCCGACTGCCGCTGGGTGCTGACGTCTGGCTTCCCACGGTTCGACA
ACGAGGGGAAATTTGCCGGCTATCGCGGCATAGGCCGCAACGTCACCACACTGGCCGGCGCCTTCGAAACCGTGGAGCAA
AACCCGTTGTCGGGCAGCGATCCCGACCGGCATCTTGCCGATCTCGAGCGGACGATGGACGCCATGCACATGGGCGTCGT
GCTTCTCGATGCCAAGCTCGACACGCTGATCGTCAACAAGGCCTATCGCGACCTGTCCAGCATTCCGGATGGTGCCGTGA
CCGTCGGCGCTCCGTTCAGCCGGTTGATGGAACTCAACCGCCGCAACGGCATCTATGGCGATATCGACGAACAGCAGTGG
CAGCGCTATCTCGCCAGCCGTATCGAGGAGATTCGCGCCGGCTCAGTCGCGCCTCGCGAATTTGTCCATGCCAGCGGCAG
GACGATGATGTTCTCGGTGACGGCGCTGTCCGGCGGCAAGCGGCTCTTGACCTATTATGAGGTCACCGAACTCAAGCGTC
GCGATGCCGAGATCGAAAGCGCCAACGCCAAGATCGCCGAGACCTTCGTCAATCTGCGCACCATGGTCGATGAGATGCCG
ATCGGTGTCCTGGTCCTCGATGCCGATATGCGCGCCGAAGTTATCAATAGCGCCTTCTATGACTTCTGGAGGATCGATCC
AGGCCGCGCCGGGATCGGCTCGGCCTTTCGCGAACTGATGGAAGCCAGCCGCGCCATCGACCCTTACGGCGCCGATGAAC
TTGCCTGGCAACGTCATACAACGGAACGCGAAGCCGAAATCAGGGCCGGCGTCGCCGGCTCCAAGCAATTGCCGCACAAT
GACGGGCGCACGCTTGTCGCATCGCTGGCGCCGCTGCCCGGCGGCAAGCGGCTCATCTCCTATGTCGACGTCACCGACAT
GAAGGGGCGCGAGACCGAGGCACAGGACGCGCGCAAGCATCTCGCCAGCGTGCTGGAATCGCTGCCGGCCGGCGTCATCA
TCTACGACCGTGACGACAAATTCGTCTTCGCCAACCGCAAGCTGCAGGACACGCTGCCAGCGCTGAAGCCCTTCTGGCAG
CCTGGCTGCAGCTTCCGCGAGGCGTTGGAATTCGGCCAGTCGATCGGCTATTTCCGCTCGAGCGGCGATGCCGGGATCGA
CAGGCTGTACGAGGTCGAACCCGAGCACTGGCTCGACAGCATGCTGGCGCGCTACCGCTTGCCAAATTCTTCCTACGAGC
GCCTCAATGCCGATGGGCGCTGGTACCAGGTCTACGACATGCGCACCGATGACGGGACGTTCATCGGCGTGCGCGTCGAC
ATCACCGACATCAAGAGCCGCGAGGCGGCGCTGCGCGACTCGATGCGCCAGATCGATCTCTTCCGCCACGTCATGGACGA
GTTGCCGGTGGCCGCCTTCATCAAGGCGCAGGATTTGAGCATCGAGTTCGTCAACAAGGCCTGGTGCGCGCTGACTGGCA
TCGCCAAGGAAGACGTCATCGGCCGGACCGACCGTGAGCTGTTTGGCACGCAAGACGCGGAAGGCTACAGCCATGACGAC
ACCCAGGTCGTGGTAACCGGCAAGGGTATTGAGGTCGAGGAGCCTGTCACCCATCGCGACGGCACGGTGCGGCAGTTGAT
GACGCGCAAGAGCCGCCTGGTGGCGACAGACGGATCGGTGCATCTGGTCGGCTCCAGCACCGACATCACCGATGTCAAGG
CGCGCGAGAAGGCTCTGGAAGAGAGCATGCGCGAAAACGAGGTGTTCCGCAGCCTGATCGACAATGTACCGGTGTCGATC
TACGCCAAGCGCTCCGATCTGAGGCAGTTCTATGTCAACAAGGGCTGGTGCGATCTGACCGGTCTCAGCAGGGAAGATGC
GATCGGCAAGACCGACATCGAGATTTTCGGGGAGGACGGCGAGGCTTTCGTGGCCGGCGATCTGGCCGTGCTGCGCACCG
GCGAAACCCAGGAGGTAGAGGAGACGGTGCGGCTTGCCGACGGCAGCGTCAGGCATCAGTTCGCGCGCAAGGGCGCGATG
ATCGCGTCGGACGGTTCGCTCTACCTGATCGGGTCAACCACCGACATCACGGAACTGAAGATGCGCGAGGCGGAACTCAG
CGAGGCGCGCCAGCGCGCCGTGCTCGCCGACCGCGCCAAGTCGGAATTCCTCGCCAATATGAGCCATGAGATCCGCACGC
CGATGAACGGTGTGCTGGGCATGGCCGAACTCCTGGCCAAATCCAATCTCGATCCCAAGCAGAAGACGTTCACCGACATC
ATCGTCAAGTCGGGCAACGCGCTGTTGACCATCATCAACGACATCCTGGATTTCTCCAAGATCGATGCCGGCCAGATGGT
GCTCGATCCGGCGCCCTTCAATCTTGCCGAGGCGATCGAGGACGTGGCGACGCTGGTGTCGACACGCGCCAAGGAAAAGG
ACCTCGAACTCATCGTGCGTGTCGAGCCGAGGCTCGAAAGCCTGTTCGTCGGCGATGTCGGCCGCATCCGGCAGATCGTC
ACCAACCTGCTCGGCAATGCGGTGAAGTTCACCGACGAAGGCCATGTGCTGGTCGACGTGACCGGTGAGAGGGTTCCGAC
CGGAACCAGGCTGACGATCTCGGTCACCGACACCGGGATCGGCATTCCCGAGGAGAAACTGAAGCTGGTGTTCGAAAAAT
TCAGCCAGGTCGACACCTCTTCGACACGGCGGCACGAGGGCACCGGGCTTGGCCTTGCCATCACCTCACGGCTGGTCGAA
CTGATGGGCGGCACCATCGGTGTCGAGAGCGCCGAGGGCAAGGGCTCGACCTTCTGGTTTACCGTGACGCTGCCCAGGGC
CGGACAGCAGAACGGGCAGCGCATCATGCCGGTGGACGTGACGGGAGCCCGCGTGCTGATCGTCGACGACAATGCCGTCA
ACCGGGCCATCCTGACCGAGCAGATGACCTCGTGGACGTTCGATTCCTGTGCGGCCGAAAGCGGCGCGGAGGGCCTCAAG
GTGCTGATCGCGGCCGCCGCCTATGGCGTGCCCGTGGATTGCGTCGTGCTCGACTACCAGATGCCCGAGATGAGCGGCGC
CGAAATGGCGCGCATCGTGCGCAACACCGGAGGCCTCGCCGACACGCCCATCATCATGCTGACCTCGGTCGACCAATCGC
TCGCCAACACCAGCTACCGCGACCTCGGCATCGACGCCCAGCTAATCAAGCCGGCGCGCTCCTCGGTGCTCCTGGAGACG
CTGGTGGCGACCATCCAGCGCCATCGCCACGCCACGGACAGCCACGCCGTCCAGCCGCTTGCAGCCGAAAGGCCTGATGT
TCCACAGCCGCCGCCGCTGGCGCTGTCCGAACAGCGCGCGCAATTGCAGCCGCCCCCGGTTCGGCCCCGGCTGCCCGCCA
CTGGCGGCGACGGACACAGGCTGGATATACTGGTGGCCGAGGACAATGAGGTGAACCAGATGGTCTTCACCCAGATCCTC
GGCGAGACCGGCTATGGTTTCGAGATCGTCGGCAATGGCCGCAAGGCGCTAGACGCTTTCGGCAAGCTCAATCCGTGCAT
GATCCTGATGGATGTCTCGATGCCGGAAATGAGCGGGCTCGAGGCGACCGCCGCGATCCGTCAGCTGGAGCAGCAAACCG
GCACACACGTGCCGATCGTCGGCGTGACAGCGCATGCGCTCAAGGGCGATCGCGAACGCTGCCTGGAGGCGGGCATGGAC
GACTATCTGCCCAAGCCGATCAGCCCCAGGGCCTTGCTGGAGAAAGTCGAGCGCTGGCTCGGCGCCGGCCGCCAGGTCCA
GCGCAACGCGGGATAG

Upstream 100 bases:

>100_bases
TGCGCCGTTAAGGTTAGCGGATCGTTAATGCTTCTCGGGCACATTCCGCCGACGAACCGCGGAGGGAGGGTTCGGCCTTG
ATTTTCGGGGTGGGGACAGG

Downstream 100 bases:

>100_bases
CTGCGCGTCGCCCGATTCCAGGGGTCCGAAGGGGCAAACCGAGGGAATCAATCGCAGATCTGCTGCTACCCCTGCGTGCA
ATGCCTATGGTGCGATCGCA

Product: hybrid sensory histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1391; Mature: 1390

Protein sequence:

>1391_residues
MAEADEAIGARGKRGPDKPVHRGDAPPCADRDSPDALRQLLEAGSDWIWETDAELRFSWLSPTYQAATGIDPADVLGRFR
FDFLNQDLKGSRSAAAHLEDLQARRPFRDFVYELKAGGADCRWVLTSGFPRFDNEGKFAGYRGIGRNVTTLAGAFETVEQ
NPLSGSDPDRHLADLERTMDAMHMGVVLLDAKLDTLIVNKAYRDLSSIPDGAVTVGAPFSRLMELNRRNGIYGDIDEQQW
QRYLASRIEEIRAGSVAPREFVHASGRTMMFSVTALSGGKRLLTYYEVTELKRRDAEIESANAKIAETFVNLRTMVDEMP
IGVLVLDADMRAEVINSAFYDFWRIDPGRAGIGSAFRELMEASRAIDPYGADELAWQRHTTEREAEIRAGVAGSKQLPHN
DGRTLVASLAPLPGGKRLISYVDVTDMKGRETEAQDARKHLASVLESLPAGVIIYDRDDKFVFANRKLQDTLPALKPFWQ
PGCSFREALEFGQSIGYFRSSGDAGIDRLYEVEPEHWLDSMLARYRLPNSSYERLNADGRWYQVYDMRTDDGTFIGVRVD
ITDIKSREAALRDSMRQIDLFRHVMDELPVAAFIKAQDLSIEFVNKAWCALTGIAKEDVIGRTDRELFGTQDAEGYSHDD
TQVVVTGKGIEVEEPVTHRDGTVRQLMTRKSRLVATDGSVHLVGSSTDITDVKAREKALEESMRENEVFRSLIDNVPVSI
YAKRSDLRQFYVNKGWCDLTGLSREDAIGKTDIEIFGEDGEAFVAGDLAVLRTGETQEVEETVRLADGSVRHQFARKGAM
IASDGSLYLIGSTTDITELKMREAELSEARQRAVLADRAKSEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTDI
IVKSGNALLTIINDILDFSKIDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRVEPRLESLFVGDVGRIRQIV
TNLLGNAVKFTDEGHVLVDVTGERVPTGTRLTISVTDTGIGIPEEKLKLVFEKFSQVDTSSTRRHEGTGLGLAITSRLVE
LMGGTIGVESAEGKGSTFWFTVTLPRAGQQNGQRIMPVDVTGARVLIVDDNAVNRAILTEQMTSWTFDSCAAESGAEGLK
VLIAAAAYGVPVDCVVLDYQMPEMSGAEMARIVRNTGGLADTPIIMLTSVDQSLANTSYRDLGIDAQLIKPARSSVLLET
LVATIQRHRHATDSHAVQPLAAERPDVPQPPPLALSEQRAQLQPPPVRPRLPATGGDGHRLDILVAEDNEVNQMVFTQIL
GETGYGFEIVGNGRKALDAFGKLNPCMILMDVSMPEMSGLEATAAIRQLEQQTGTHVPIVGVTAHALKGDRERCLEAGMD
DYLPKPISPRALLEKVERWLGAGRQVQRNAG

Sequences:

>Translated_1391_residues
MAEADEAIGARGKRGPDKPVHRGDAPPCADRDSPDALRQLLEAGSDWIWETDAELRFSWLSPTYQAATGIDPADVLGRFR
FDFLNQDLKGSRSAAAHLEDLQARRPFRDFVYELKAGGADCRWVLTSGFPRFDNEGKFAGYRGIGRNVTTLAGAFETVEQ
NPLSGSDPDRHLADLERTMDAMHMGVVLLDAKLDTLIVNKAYRDLSSIPDGAVTVGAPFSRLMELNRRNGIYGDIDEQQW
QRYLASRIEEIRAGSVAPREFVHASGRTMMFSVTALSGGKRLLTYYEVTELKRRDAEIESANAKIAETFVNLRTMVDEMP
IGVLVLDADMRAEVINSAFYDFWRIDPGRAGIGSAFRELMEASRAIDPYGADELAWQRHTTEREAEIRAGVAGSKQLPHN
DGRTLVASLAPLPGGKRLISYVDVTDMKGRETEAQDARKHLASVLESLPAGVIIYDRDDKFVFANRKLQDTLPALKPFWQ
PGCSFREALEFGQSIGYFRSSGDAGIDRLYEVEPEHWLDSMLARYRLPNSSYERLNADGRWYQVYDMRTDDGTFIGVRVD
ITDIKSREAALRDSMRQIDLFRHVMDELPVAAFIKAQDLSIEFVNKAWCALTGIAKEDVIGRTDRELFGTQDAEGYSHDD
TQVVVTGKGIEVEEPVTHRDGTVRQLMTRKSRLVATDGSVHLVGSSTDITDVKAREKALEESMRENEVFRSLIDNVPVSI
YAKRSDLRQFYVNKGWCDLTGLSREDAIGKTDIEIFGEDGEAFVAGDLAVLRTGETQEVEETVRLADGSVRHQFARKGAM
IASDGSLYLIGSTTDITELKMREAELSEARQRAVLADRAKSEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTDI
IVKSGNALLTIINDILDFSKIDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRVEPRLESLFVGDVGRIRQIV
TNLLGNAVKFTDEGHVLVDVTGERVPTGTRLTISVTDTGIGIPEEKLKLVFEKFSQVDTSSTRRHEGTGLGLAITSRLVE
LMGGTIGVESAEGKGSTFWFTVTLPRAGQQNGQRIMPVDVTGARVLIVDDNAVNRAILTEQMTSWTFDSCAAESGAEGLK
VLIAAAAYGVPVDCVVLDYQMPEMSGAEMARIVRNTGGLADTPIIMLTSVDQSLANTSYRDLGIDAQLIKPARSSVLLET
LVATIQRHRHATDSHAVQPLAAERPDVPQPPPLALSEQRAQLQPPPVRPRLPATGGDGHRLDILVAEDNEVNQMVFTQIL
GETGYGFEIVGNGRKALDAFGKLNPCMILMDVSMPEMSGLEATAAIRQLEQQTGTHVPIVGVTAHALKGDRERCLEAGMD
DYLPKPISPRALLEKVERWLGAGRQVQRNAG
>Mature_1390_residues
AEADEAIGARGKRGPDKPVHRGDAPPCADRDSPDALRQLLEAGSDWIWETDAELRFSWLSPTYQAATGIDPADVLGRFRF
DFLNQDLKGSRSAAAHLEDLQARRPFRDFVYELKAGGADCRWVLTSGFPRFDNEGKFAGYRGIGRNVTTLAGAFETVEQN
PLSGSDPDRHLADLERTMDAMHMGVVLLDAKLDTLIVNKAYRDLSSIPDGAVTVGAPFSRLMELNRRNGIYGDIDEQQWQ
RYLASRIEEIRAGSVAPREFVHASGRTMMFSVTALSGGKRLLTYYEVTELKRRDAEIESANAKIAETFVNLRTMVDEMPI
GVLVLDADMRAEVINSAFYDFWRIDPGRAGIGSAFRELMEASRAIDPYGADELAWQRHTTEREAEIRAGVAGSKQLPHND
GRTLVASLAPLPGGKRLISYVDVTDMKGRETEAQDARKHLASVLESLPAGVIIYDRDDKFVFANRKLQDTLPALKPFWQP
GCSFREALEFGQSIGYFRSSGDAGIDRLYEVEPEHWLDSMLARYRLPNSSYERLNADGRWYQVYDMRTDDGTFIGVRVDI
TDIKSREAALRDSMRQIDLFRHVMDELPVAAFIKAQDLSIEFVNKAWCALTGIAKEDVIGRTDRELFGTQDAEGYSHDDT
QVVVTGKGIEVEEPVTHRDGTVRQLMTRKSRLVATDGSVHLVGSSTDITDVKAREKALEESMRENEVFRSLIDNVPVSIY
AKRSDLRQFYVNKGWCDLTGLSREDAIGKTDIEIFGEDGEAFVAGDLAVLRTGETQEVEETVRLADGSVRHQFARKGAMI
ASDGSLYLIGSTTDITELKMREAELSEARQRAVLADRAKSEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTDII
VKSGNALLTIINDILDFSKIDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRVEPRLESLFVGDVGRIRQIVT
NLLGNAVKFTDEGHVLVDVTGERVPTGTRLTISVTDTGIGIPEEKLKLVFEKFSQVDTSSTRRHEGTGLGLAITSRLVEL
MGGTIGVESAEGKGSTFWFTVTLPRAGQQNGQRIMPVDVTGARVLIVDDNAVNRAILTEQMTSWTFDSCAAESGAEGLKV
LIAAAAYGVPVDCVVLDYQMPEMSGAEMARIVRNTGGLADTPIIMLTSVDQSLANTSYRDLGIDAQLIKPARSSVLLETL
VATIQRHRHATDSHAVQPLAAERPDVPQPPPLALSEQRAQLQPPPVRPRLPATGGDGHRLDILVAEDNEVNQMVFTQILG
ETGYGFEIVGNGRKALDAFGKLNPCMILMDVSMPEMSGLEATAAIRQLEQQTGTHVPIVGVTAHALKGDRERCLEAGMDD
YLPKPISPRALLEKVERWLGAGRQVQRNAG

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=589, Percent_Identity=33.276740237691, Blast_Score=280, Evalue=3e-76,
Organism=Escherichia coli, GI48994928, Length=508, Percent_Identity=28.9370078740157, Blast_Score=189, Evalue=8e-49,
Organism=Escherichia coli, GI87081816, Length=350, Percent_Identity=35.1428571428571, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI145693157, Length=283, Percent_Identity=37.1024734982332, Blast_Score=173, Evalue=6e-44,
Organism=Escherichia coli, GI1788713, Length=404, Percent_Identity=31.1881188118812, Blast_Score=165, Evalue=2e-41,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=30.1587301587302, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=29.7413793103448, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=29.8319327731092, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=343, Percent_Identity=25.9475218658892, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=30.0884955752212, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=28.0851063829787, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=26.9565217391304, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=35.3448275862069, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1790300, Length=272, Percent_Identity=26.8382352941176, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=135, Percent_Identity=37.7777777777778, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323034, Length=162, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 153213; Mature: 153082

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEADEAIGARGKRGPDKPVHRGDAPPCADRDSPDALRQLLEAGSDWIWETDAELRFSWL
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEEEEEC
SPTYQAATGIDPADVLGRFRFDFLNQDLKGSRSAAAHLEDLQARRPFRDFVYELKAGGAD
CCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
CRWVLTSGFPRFDNEGKFAGYRGIGRNVTTLAGAFETVEQNPLSGSDPDRHLADLERTMD
EEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AMHMGVVLLDAKLDTLIVNKAYRDLSSIPDGAVTVGAPFSRLMELNRRNGIYGDIDEQQW
HHHHCEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHH
QRYLASRIEEIRAGSVAPREFVHASGRTMMFSVTALSGGKRLLTYYEVTELKRRDAEIES
HHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEEEECCCCEEEEHHHHHHHHHHCCHHHH
ANAKIAETFVNLRTMVDEMPIGVLVLDADMRAEVINSAFYDFWRIDPGRAGIGSAFRELM
CCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
EASRAIDPYGADELAWQRHTTEREAEIRAGVAGSKQLPHNDGRTLVASLAPLPGGKRLIS
HHHHCCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHEEE
YVDVTDMKGRETEAQDARKHLASVLESLPAGVIIYDRDDKFVFANRKLQDTLPALKPFWQ
EECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHCC
PGCSFREALEFGQSIGYFRSSGDAGIDRLYEVEPEHWLDSMLARYRLPNSSYERLNADGR
CCCCHHHHHHHHHHHCHHHCCCCCCCHHHEECCHHHHHHHHHHHHCCCCCHHHHCCCCCC
WYQVYDMRTDDGTFIGVRVDITDIKSREAALRDSMRQIDLFRHVMDELPVAAFIKAQDLS
EEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
IEFVNKAWCALTGIAKEDVIGRTDRELFGTQDAEGYSHDDTQVVVTGKGIEVEEPVTHRD
EHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
GTVRQLMTRKSRLVATDGSVHLVGSSTDITDVKAREKALEESMRENEVFRSLIDNVPVSI
CHHHHHHHHHHHEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YAKRSDLRQFYVNKGWCDLTGLSREDAIGKTDIEIFGEDGEAFVAGDLAVLRTGETQEVE
EECHHHHHHHHHCCCEEEECCCCHHCCCCCCCEEEECCCCCEEEECCEEEEECCCHHHHH
ETVRLADGSVRHQFARKGAMIASDGSLYLIGSTTDITELKMREAELSEARQRAVLADRAK
HHHHHCCCHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTDIIVKSGNALLTIINDILDFSK
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRVEPRLESLFVGDVGRIRQIV
CCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCHHHHHHHH
TNLLGNAVKFTDEGHVLVDVTGERVPTGTRLTISVTDTGIGIPEEKLKLVFEKFSQVDTS
HHHHCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCC
STRRHEGTGLGLAITSRLVELMGGTIGVESAEGKGSTFWFTVTLPRAGQQNGQRIMPVDV
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEC
TGARVLIVDDNAVNRAILTEQMTSWTFDSCAAESGAEGLKVLIAAAAYGVPVDCVVLDYQ
CCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEEE
MPEMSGAEMARIVRNTGGLADTPIIMLTSVDQSLANTSYRDLGIDAQLIKPARSSVLLET
CCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHCCCCHHCCCCHHHHHHHHHHHHHHH
LVATIQRHRHATDSHAVQPLAAERPDVPQPPPLALSEQRAQLQPPPVRPRLPATGGDGHR
HHHHHHHHHCCCCHHCCCCHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCE
LDILVAEDNEVNQMVFTQILGETGYGFEIVGNGRKALDAFGKLNPCMILMDVSMPEMSGL
EEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCEEEEEECCCCCCCCC
EATAAIRQLEQQTGTHVPIVGVTAHALKGDRERCLEAGMDDYLPKPISPRALLEKVERWL
HHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHHHHHHCCCHHCCCCCCCHHHHHHHHHHHH
GAGRQVQRNAG
CCCCCHHCCCC
>Mature Secondary Structure 
AEADEAIGARGKRGPDKPVHRGDAPPCADRDSPDALRQLLEAGSDWIWETDAELRFSWL
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEEEEEC
SPTYQAATGIDPADVLGRFRFDFLNQDLKGSRSAAAHLEDLQARRPFRDFVYELKAGGAD
CCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
CRWVLTSGFPRFDNEGKFAGYRGIGRNVTTLAGAFETVEQNPLSGSDPDRHLADLERTMD
EEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AMHMGVVLLDAKLDTLIVNKAYRDLSSIPDGAVTVGAPFSRLMELNRRNGIYGDIDEQQW
HHHHCEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHH
QRYLASRIEEIRAGSVAPREFVHASGRTMMFSVTALSGGKRLLTYYEVTELKRRDAEIES
HHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEEEECCCCEEEEHHHHHHHHHHCCHHHH
ANAKIAETFVNLRTMVDEMPIGVLVLDADMRAEVINSAFYDFWRIDPGRAGIGSAFRELM
CCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
EASRAIDPYGADELAWQRHTTEREAEIRAGVAGSKQLPHNDGRTLVASLAPLPGGKRLIS
HHHHCCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHEEE
YVDVTDMKGRETEAQDARKHLASVLESLPAGVIIYDRDDKFVFANRKLQDTLPALKPFWQ
EECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHCC
PGCSFREALEFGQSIGYFRSSGDAGIDRLYEVEPEHWLDSMLARYRLPNSSYERLNADGR
CCCCHHHHHHHHHHHCHHHCCCCCCCHHHEECCHHHHHHHHHHHHCCCCCHHHHCCCCCC
WYQVYDMRTDDGTFIGVRVDITDIKSREAALRDSMRQIDLFRHVMDELPVAAFIKAQDLS
EEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
IEFVNKAWCALTGIAKEDVIGRTDRELFGTQDAEGYSHDDTQVVVTGKGIEVEEPVTHRD
EHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
GTVRQLMTRKSRLVATDGSVHLVGSSTDITDVKAREKALEESMRENEVFRSLIDNVPVSI
CHHHHHHHHHHHEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YAKRSDLRQFYVNKGWCDLTGLSREDAIGKTDIEIFGEDGEAFVAGDLAVLRTGETQEVE
EECHHHHHHHHHCCCEEEECCCCHHCCCCCCCEEEECCCCCEEEECCEEEEECCCHHHHH
ETVRLADGSVRHQFARKGAMIASDGSLYLIGSTTDITELKMREAELSEARQRAVLADRAK
HHHHHCCCHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTDIIVKSGNALLTIINDILDFSK
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRVEPRLESLFVGDVGRIRQIV
CCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCHHHHHHHH
TNLLGNAVKFTDEGHVLVDVTGERVPTGTRLTISVTDTGIGIPEEKLKLVFEKFSQVDTS
HHHHCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCC
STRRHEGTGLGLAITSRLVELMGGTIGVESAEGKGSTFWFTVTLPRAGQQNGQRIMPVDV
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEC
TGARVLIVDDNAVNRAILTEQMTSWTFDSCAAESGAEGLKVLIAAAAYGVPVDCVVLDYQ
CCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEEE
MPEMSGAEMARIVRNTGGLADTPIIMLTSVDQSLANTSYRDLGIDAQLIKPARSSVLLET
CCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHCCCCHHCCCCHHHHHHHHHHHHHHH
LVATIQRHRHATDSHAVQPLAAERPDVPQPPPLALSEQRAQLQPPPVRPRLPATGGDGHR
HHHHHHHHHCCCCHHCCCCHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCE
LDILVAEDNEVNQMVFTQILGETGYGFEIVGNGRKALDAFGKLNPCMILMDVSMPEMSGL
EEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCEEEEEECCCCCCCCC
EATAAIRQLEQQTGTHVPIVGVTAHALKGDRERCLEAGMDDYLPKPISPRALLEKVERWL
HHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHHHHHHCCCHHCCCCCCCHHHHHHHHHHHH
GAGRQVQRNAG
CCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]