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The map label for this gene is bmrU [H]

Identifier: 13473177

GI number: 13473177

Start: 2977802

End: 2978905

Strand: Direct

Name: bmrU [H]

Synonym: mlr3686

Alternate gene names: 13473177

Gene position: 2977802-2978905 (Clockwise)

Preceding gene: 13473175

Following gene: 13473179

Centisome position: 42.32

GC content: 63.77

Gene sequence:

>1104_bases
ATGCTGTTGTTCCGACAAAATTGGCGTGGATTTCGCGCCGGAAAAACACGCAGCAGTTGCGCGGGCGGCTGTGAACACGC
GCTGAATCGCACCGTTTCCAACGGAACCTTTCCGGCATCGCCACGTTTCAGCCTGCGGCTGGGTTCGTCCCGGCCCTTTT
GGGCTGACCTAACGGAGCGGGGCATGAAATTTGCTGCGGTGCTGAACCGGGATGGCGGCACCTTGCGCACCACCGACCTC
GCCGCCTTTTCCGACAGGATGCGCCAGACGCTGGAGGCGGCAGGCCATTCCTTGAGCATTGACGTGGTTGCCGGCAAGGA
CGTTGTGGAAACCCTCGACAACGCTGCCTCGCGCCGCGCCGTCGATGTCGTGCTGGCGGGTGGCGGCGACGGAACCATTT
CGGCGGCGGCCGCGAGGCTGATGGGCAAGAAAAAGGCGCTTGCCATCCTGCCGGCCGGCACCATGAACCTGTTCGCGCGT
GGCCTGGGCATTCCGCAGTCGCTCGACGCCGCGCTGAAATCCTTCGCCGACGGTGAGATCATCGCCGTCGACATGGCCAC
CGCCAACGGCCGGCCCTTCATCCACCAGTTCTCGATCGGCATGCACGCCAAGATGGTGCAGTTGCGCCAGGGAATGGAAT
TCGGCTCGCGGCTGGGCAAGATCGGTGCTTCGGCCAAGGCGGCATGGGCGACAATCAACAACCCGCCGGCGATGAACGTC
ACGCTCGCTGTCGGCAAGGCCGAGATGACGGCGCGCATCTCAGGCATCGGCGTCACCAACAATCTGTTCGGCGAAGGCCA
TCTGCCCTATGCGGACAACCCTTCGGGTGGGGTGCTCGGCATCTATGTCACGGTGGCGCAGCAGCGCGCCGAACTGGTGA
AATTCTTCTTCGACGTGGCGCGCGGCAGATGGCGCGACAATGAACATGTCGAAATCCATCAGGCCGACCGCACCGTCCTG
AAAATCCATTCCGGCAGCAGAAAGTTCCGCGCCGTCATGGATGGCGAATTGGTCAGGCTCGAGCGGGAGACGACGATCGA
AATCCGGCCCGGCGCGCTGAATGTCCTGGTGCCGGCCAGCATCGCCGCGGCTAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
TAGTCTCTCCTGGTGCGTGATTTCGTGCACGCCGCGCCCGCTTGAACCGTCGCTGGGAAGATCGGGCGCGGCATCTCCAC
GGGTTCACAACGTCGTGACC

Downstream 100 bases:

>100_bases
TGCGATCTCCAACGATGACGGCCGAAAATCTAGCCGCTCGGCGCACTTCCTTGCTGCGTCGCCGGTGTCTTGGCCACCTC
GCCATAGATTTCAGCGATGC

Product: multidrug resistance protein BmrU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MLLFRQNWRGFRAGKTRSSCAGGCEHALNRTVSNGTFPASPRFSLRLGSSRPFWADLTERGMKFAAVLNRDGGTLRTTDL
AAFSDRMRQTLEAAGHSLSIDVVAGKDVVETLDNAASRRAVDVVLAGGGDGTISAAAARLMGKKKALAILPAGTMNLFAR
GLGIPQSLDAALKSFADGEIIAVDMATANGRPFIHQFSIGMHAKMVQLRQGMEFGSRLGKIGASAKAAWATINNPPAMNV
TLAVGKAEMTARISGIGVTNNLFGEGHLPYADNPSGGVLGIYVTVAQQRAELVKFFFDVARGRWRDNEHVEIHQADRTVL
KIHSGSRKFRAVMDGELVRLERETTIEIRPGALNVLVPASIAAAKAA

Sequences:

>Translated_367_residues
MLLFRQNWRGFRAGKTRSSCAGGCEHALNRTVSNGTFPASPRFSLRLGSSRPFWADLTERGMKFAAVLNRDGGTLRTTDL
AAFSDRMRQTLEAAGHSLSIDVVAGKDVVETLDNAASRRAVDVVLAGGGDGTISAAAARLMGKKKALAILPAGTMNLFAR
GLGIPQSLDAALKSFADGEIIAVDMATANGRPFIHQFSIGMHAKMVQLRQGMEFGSRLGKIGASAKAAWATINNPPAMNV
TLAVGKAEMTARISGIGVTNNLFGEGHLPYADNPSGGVLGIYVTVAQQRAELVKFFFDVARGRWRDNEHVEIHQADRTVL
KIHSGSRKFRAVMDGELVRLERETTIEIRPGALNVLVPASIAAAKAA
>Mature_367_residues
MLLFRQNWRGFRAGKTRSSCAGGCEHALNRTVSNGTFPASPRFSLRLGSSRPFWADLTERGMKFAAVLNRDGGTLRTTDL
AAFSDRMRQTLEAAGHSLSIDVVAGKDVVETLDNAASRRAVDVVLAGGGDGTISAAAARLMGKKKALAILPAGTMNLFAR
GLGIPQSLDAALKSFADGEIIAVDMATANGRPFIHQFSIGMHAKMVQLRQGMEFGSRLGKIGASAKAAWATINNPPAMNV
TLAVGKAEMTARISGIGVTNNLFGEGHLPYADNPSGGVLGIYVTVAQQRAELVKFFFDVARGRWRDNEHVEIHQADRTVL
KIHSGSRKFRAVMDGELVRLERETTIEIRPGALNVLVPASIAAAKAA

Specific function: May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro [H]

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=78, Percent_Identity=47.4358974358974, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: NA

Molecular weight: Translated: 39167; Mature: 39167

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFRQNWRGFRAGKTRSSCAGGCEHALNRTVSNGTFPASPRFSLRLGSSRPFWADLTER
CEEECCCCCCCCCCCCCCHHCCHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHC
GMKFAAVLNRDGGTLRTTDLAAFSDRMRQTLEAAGHSLSIDVVAGKDVVETLDNAASRRA
CCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHCCCE
VDVVLAGGGDGTISAAAARLMGKKKALAILPAGTMNLFARGLGIPQSLDAALKSFADGEI
EEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCCE
IAVDMATANGRPFIHQFSIGMHAKMVQLRQGMEFGSRLGKIGASAKAAWATINNPPAMNV
EEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
TLAVGKAEMTARISGIGVTNNLFGEGHLPYADNPSGGVLGIYVTVAQQRAELVKFFFDVA
EEEECCCEEEEEEEECCEECCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHH
RGRWRDNEHVEIHQADRTVLKIHSGSRKFRAVMDGELVRLERETTIEIRPGALNVLVPAS
HCCCCCCCCEEEEECCCEEEEEECCCCEEEEECCCEEEEEECCCEEEECCCEEEEEECCH
IAAAKAA
HHHHCCC
>Mature Secondary Structure
MLLFRQNWRGFRAGKTRSSCAGGCEHALNRTVSNGTFPASPRFSLRLGSSRPFWADLTER
CEEECCCCCCCCCCCCCCHHCCHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHC
GMKFAAVLNRDGGTLRTTDLAAFSDRMRQTLEAAGHSLSIDVVAGKDVVETLDNAASRRA
CCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHCCCE
VDVVLAGGGDGTISAAAARLMGKKKALAILPAGTMNLFARGLGIPQSLDAALKSFADGEI
EEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCCE
IAVDMATANGRPFIHQFSIGMHAKMVQLRQGMEFGSRLGKIGASAKAAWATINNPPAMNV
EEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
TLAVGKAEMTARISGIGVTNNLFGEGHLPYADNPSGGVLGIYVTVAQQRAELVKFFFDVA
EEEECCCEEEEEEEECCEECCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHH
RGRWRDNEHVEIHQADRTVLKIHSGSRKFRAVMDGELVRLERETTIEIRPGALNVLVPAS
HCCCCCCCCEEEEECCCEEEEEECCCCEEEEECCCEEEEEECCCEEEECCCEEEEEECCH
IAAAKAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377 [H]