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The map label for this gene is potC [H]

Identifier: 13473160

GI number: 13473160

Start: 2959503

End: 2960324

Strand: Direct

Name: potC [H]

Synonym: mlr3665

Alternate gene names: 13473160

Gene position: 2959503-2960324 (Clockwise)

Preceding gene: 13473159

Following gene: 13473161

Centisome position: 42.06

GC content: 63.63

Gene sequence:

>822_bases
ATGAGGGTGCGGGGTTTCCTGTCGGGCGGCTGGCTGTCCGTCTATGCGTTCCTCTATATCGTCTTCCTCTATCTGCCCGT
GATCTTCCTGCCGATCTTCTCGATCAACACGGCGCCGACGCCGAAATTCCCGCTCACCGGCTTCACCTTGCAATGGTATG
CGGACCTGCCGCACACGCCGGCTCTGCTCGACGCCGCCTGGAACAGCCTGAAAGTCGGCGTCTGCGCCTCGGTTCTGGCC
ACCGTGCTCGGCATCCTCGCCGCCCGTTCGATCACCCGCTACCGCTATCCCGGCCGCCGCACCATCAACGGCCTGATCAT
GGCGCCATTGGTGCTGCCCGAGGTGATCGTCGCCATCTCGATGCTGCTGGTGATGCTACAGCTGGGCCTCAGCCTCTCGC
TGTTCACCGTCGTGCTGGGCCACGTGCTGGTCTGCATCCCCTATTCGATGACGGTGCTGACCTCCGGTTTCGAAGGCTTC
GACCGCAGCCTCGAGGAAGCTTCCGCCGATCTCGGCGAAAGCGCCTTCGGCACCTTCCGCCGTGTGACGCTGCCGATGGT
GGCGCCGGCCATCATCTCCAGCCTGCTCGTCTGCTTCACCATCTCGCTCGACGAGTTCATCATCGCCTTCTTCCTGACCG
GCACCGAAGCGACGCTGCCGATCTACATCTGGGGCCAGTTGCGTTTCGCCTCGAAACTGCCCGGCGTGCTGGCACTGGGC
ACGCTGCTTCTGGTTGCCTCTTTCCTGTTGATGACAATCGCCGAAATCCTGCGCCGCCGCGCGGCCAGACGCACCCAGAA
CGAGGGAGGCCTCTATGCCTGA

Upstream 100 bases:

>100_bases
GGCCGCTGGGTGCCGCGCTTTCCGTCACCACCATGCTGATCGTCACCCTGATGGCCGGCGCCACGGTTCTGATCATCCGC
GCACTGCAGAGGCTGGCACG

Downstream 100 bases:

>100_bases
ACAGCCGATCGAGCGCCCCCAATCTGACCAGGCCCAGTCTGACCGGGCCCAATCCGATCGGGCAATGATCGAGATCCGCA
ACGTCACCCGCAGCTATGGA

Product: spermidine/putrescine ABC transporter, permease protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRVRGFLSGGWLSVYAFLYIVFLYLPVIFLPIFSINTAPTPKFPLTGFTLQWYADLPHTPALLDAAWNSLKVGVCASVLA
TVLGILAARSITRYRYPGRRTINGLIMAPLVLPEVIVAISMLLVMLQLGLSLSLFTVVLGHVLVCIPYSMTVLTSGFEGF
DRSLEEASADLGESAFGTFRRVTLPMVAPAIISSLLVCFTISLDEFIIAFFLTGTEATLPIYIWGQLRFASKLPGVLALG
TLLLVASFLLMTIAEILRRRAARRTQNEGGLYA

Sequences:

>Translated_273_residues
MRVRGFLSGGWLSVYAFLYIVFLYLPVIFLPIFSINTAPTPKFPLTGFTLQWYADLPHTPALLDAAWNSLKVGVCASVLA
TVLGILAARSITRYRYPGRRTINGLIMAPLVLPEVIVAISMLLVMLQLGLSLSLFTVVLGHVLVCIPYSMTVLTSGFEGF
DRSLEEASADLGESAFGTFRRVTLPMVAPAIISSLLVCFTISLDEFIIAFFLTGTEATLPIYIWGQLRFASKLPGVLALG
TLLLVASFLLMTIAEILRRRAARRTQNEGGLYA
>Mature_273_residues
MRVRGFLSGGWLSVYAFLYIVFLYLPVIFLPIFSINTAPTPKFPLTGFTLQWYADLPHTPALLDAAWNSLKVGVCASVLA
TVLGILAARSITRYRYPGRRTINGLIMAPLVLPEVIVAISMLLVMLQLGLSLSLFTVVLGHVLVCIPYSMTVLTSGFEGF
DRSLEEASADLGESAFGTFRRVTLPMVAPAIISSLLVCFTISLDEFIIAFFLTGTEATLPIYIWGQLRFASKLPGVLALG
TLLLVASFLLMTIAEILRRRAARRTQNEGGLYA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=237, Percent_Identity=30.379746835443, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787081, Length=272, Percent_Identity=35.6617647058824, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787714, Length=224, Percent_Identity=33.0357142857143, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788764, Length=175, Percent_Identity=25.1428571428571, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787571, Length=197, Percent_Identity=27.9187817258883, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29858; Mature: 29858

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRGFLSGGWLSVYAFLYIVFLYLPVIFLPIFSINTAPTPKFPLTGFTLQWYADLPHTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCH
ALLDAAWNSLKVGVCASVLATVLGILAARSITRYRYPGRRTINGLIMAPLVLPEVIVAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
MLLVMLQLGLSLSLFTVVLGHVLVCIPYSMTVLTSGFEGFDRSLEEASADLGESAFGTFR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHH
RVTLPMVAPAIISSLLVCFTISLDEFIIAFFLTGTEATLPIYIWGQLRFASKLPGVLALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHCCHHHHHH
TLLLVASFLLMTIAEILRRRAARRTQNEGGLYA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRVRGFLSGGWLSVYAFLYIVFLYLPVIFLPIFSINTAPTPKFPLTGFTLQWYADLPHTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCH
ALLDAAWNSLKVGVCASVLATVLGILAARSITRYRYPGRRTINGLIMAPLVLPEVIVAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
MLLVMLQLGLSLSLFTVVLGHVLVCIPYSMTVLTSGFEGFDRSLEEASADLGESAFGTFR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHH
RVTLPMVAPAIISSLLVCFTISLDEFIIAFFLTGTEATLPIYIWGQLRFASKLPGVLALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHCCHHHHHH
TLLLVASFLLMTIAEILRRRAARRTQNEGGLYA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]