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The map label for this gene is hipO [H]

Identifier: 13473092

GI number: 13473092

Start: 2886781

End: 2887944

Strand: Direct

Name: hipO [H]

Synonym: mlr3583

Alternate gene names: 13473092

Gene position: 2886781-2887944 (Clockwise)

Preceding gene: 13473091

Following gene: 13473093

Centisome position: 41.03

GC content: 63.75

Gene sequence:

>1164_bases
ATGCCAATCCTGAACCGCGCCGCTGAAATGCAGGACGAAGTCGCCGGCTGGCGCCGGCATCTGCACCAAACGCCGGAGCT
GAACTTCGATGTCTTCAAGACGGCGGCTTTCGTCACCGAAAAGCTGAAAGAGTTCGGTTGCGACGATGTGGTCACCGGCC
TCGGCAAGACCGGCGTCGTCGGCATCATCCGCGGCCGCCAGGGCGAAGGCGCCACCATCGGCCTGCGCGCCGACATGGAT
GCGCTGCCGCTCAACGAAATCACCGGAAAGCCCTATGCCTCGACCGTCCCCGGCAAGATGCACGCATGCGGACATGACGG
CCACACGGCGATGCTTTTGGGGGCCGCGAAATATCTCGCCGAGACGCGCAATTTTGCCGGCTCCGTGGCGGTGATCTTCC
AGCCGGCGGAGGAAGGCGGCGGCGGCGGCAATGAAATGGTCAAGGACGGCATGATGGAGCGTTTCGACATCTCCAAAGTG
TTCGGCATGCACAACATGCCGGGCTTGCCCGTCGGCCAGTTCGCCATCCGCCCGGGTCCGATCATGGCGGCAACGGCCGA
ATTCACCATCACCGTTAAAGGTCGGGGCGGCCATGCCGCGATGCCGCACGGCACGATCGATCCGATCGTCATCACCAGCC
AACTGGTCGGCGCGCTGCAGACGATCGCCTCGCGCAGCACCGATCCGGTCGAGGCCGTGGTGGTCTCGGTGACCAAGTTT
CATGCCGGCGACGCCTACAACATCATCCCGGAATCGGCCGAGATCGCCGGCACCGTGCGCACCTTGCGCAAGGAGATCGC
CAAGAAATCCGAAGAGTGCATCCGCACCATCTGCGACGGCCTGGCGACCGCTTTCGGCGCCAAGATCGAGGTCGACTACC
AGGCAAATTACCCCGTCACCTTCAATCACGCCGAAGAGACGGTGTTTGCCAGCGATATCGCGGCCAATGTCGCCGGAGAC
GCCTATGTCCACCGCGGCATCCAGCCGGTGATGGGCGGCGAGGATTTCTCCTACATGCTGGAGGCCCGCCCCGGCGCCTT
TATCTTCATCGGCAATGGTGACACCGCCGGCCTTCACAACCCGGCCTACGATTTCAACGACGAGGCCATCCCGCACGGCA
TGAGCTACTGGGTGAAGCTGGCGGAAACCGCGCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
ACAATCACAATTCCAAAACCCCGGCGCAATTGCAAAACCCCGGGCACAATTGCAAAACACCAGGCTGAAGCCGGCTGCTC
CAACAACGAATGGAACCATC

Downstream 100 bases:

>100_bases
TGAGCACCGCCCAAGGGGCCGGCCAATTGCATACGGCCGGCCTCTTGGCGAAACGGTCCGAAGCGGCTATGTGTCGGGCC
GCGTGGTCCCGTAGCTCAGT

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPILNRAAEMQDEVAGWRRHLHQTPELNFDVFKTAAFVTEKLKEFGCDDVVTGLGKTGVVGIIRGRQGEGATIGLRADMD
ALPLNEITGKPYASTVPGKMHACGHDGHTAMLLGAAKYLAETRNFAGSVAVIFQPAEEGGGGGNEMVKDGMMERFDISKV
FGMHNMPGLPVGQFAIRPGPIMAATAEFTITVKGRGGHAAMPHGTIDPIVITSQLVGALQTIASRSTDPVEAVVVSVTKF
HAGDAYNIIPESAEIAGTVRTLRKEIAKKSEECIRTICDGLATAFGAKIEVDYQANYPVTFNHAEETVFASDIAANVAGD
AYVHRGIQPVMGGEDFSYMLEARPGAFIFIGNGDTAGLHNPAYDFNDEAIPHGMSYWVKLAETALAA

Sequences:

>Translated_387_residues
MPILNRAAEMQDEVAGWRRHLHQTPELNFDVFKTAAFVTEKLKEFGCDDVVTGLGKTGVVGIIRGRQGEGATIGLRADMD
ALPLNEITGKPYASTVPGKMHACGHDGHTAMLLGAAKYLAETRNFAGSVAVIFQPAEEGGGGGNEMVKDGMMERFDISKV
FGMHNMPGLPVGQFAIRPGPIMAATAEFTITVKGRGGHAAMPHGTIDPIVITSQLVGALQTIASRSTDPVEAVVVSVTKF
HAGDAYNIIPESAEIAGTVRTLRKEIAKKSEECIRTICDGLATAFGAKIEVDYQANYPVTFNHAEETVFASDIAANVAGD
AYVHRGIQPVMGGEDFSYMLEARPGAFIFIGNGDTAGLHNPAYDFNDEAIPHGMSYWVKLAETALAA
>Mature_386_residues
PILNRAAEMQDEVAGWRRHLHQTPELNFDVFKTAAFVTEKLKEFGCDDVVTGLGKTGVVGIIRGRQGEGATIGLRADMDA
LPLNEITGKPYASTVPGKMHACGHDGHTAMLLGAAKYLAETRNFAGSVAVIFQPAEEGGGGGNEMVKDGMMERFDISKVF
GMHNMPGLPVGQFAIRPGPIMAATAEFTITVKGRGGHAAMPHGTIDPIVITSQLVGALQTIASRSTDPVEAVVVSVTKFH
AGDAYNIIPESAEIAGTVRTLRKEIAKKSEECIRTICDGLATAFGAKIEVDYQANYPVTFNHAEETVFASDIAANVAGDA
YVHRGIQPVMGGEDFSYMLEARPGAFIFIGNGDTAGLHNPAYDFNDEAIPHGMSYWVKLAETALAA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=431, Percent_Identity=28.7703016241299, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41180; Mature: 41049

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILNRAAEMQDEVAGWRRHLHQTPELNFDVFKTAAFVTEKLKEFGCDDVVTGLGKTGVV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEE
GIIRGRQGEGATIGLRADMDALPLNEITGKPYASTVPGKMHACGHDGHTAMLLGAAKYLA
EEEECCCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHH
ETRNFAGSVAVIFQPAEEGGGGGNEMVKDGMMERFDISKVFGMHNMPGLPVGQFAIRPGP
HHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
IMAATAEFTITVKGRGGHAAMPHGTIDPIVITSQLVGALQTIASRSTDPVEAVVVSVTKF
EEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
HAGDAYNIIPESAEIAGTVRTLRKEIAKKSEECIRTICDGLATAFGAKIEVDYQANYPVT
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEE
FNHAEETVFASDIAANVAGDAYVHRGIQPVMGGEDFSYMLEARPGAFIFIGNGDTAGLHN
ECCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCC
PAYDFNDEAIPHGMSYWVKLAETALAA
CCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PILNRAAEMQDEVAGWRRHLHQTPELNFDVFKTAAFVTEKLKEFGCDDVVTGLGKTGVV
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEE
GIIRGRQGEGATIGLRADMDALPLNEITGKPYASTVPGKMHACGHDGHTAMLLGAAKYLA
EEEECCCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHH
ETRNFAGSVAVIFQPAEEGGGGGNEMVKDGMMERFDISKVFGMHNMPGLPVGQFAIRPGP
HHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
IMAATAEFTITVKGRGGHAAMPHGTIDPIVITSQLVGALQTIASRSTDPVEAVVVSVTKF
EEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
HAGDAYNIIPESAEIAGTVRTLRKEIAKKSEECIRTICDGLATAFGAKIEVDYQANYPVT
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEE
FNHAEETVFASDIAANVAGDAYVHRGIQPVMGGEDFSYMLEARPGAFIFIGNGDTAGLHN
ECCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCC
PAYDFNDEAIPHGMSYWVKLAETALAA
CCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]