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The map label for this gene is nudG [H]

Identifier: 13472989

GI number: 13472989

Start: 2788135

End: 2788557

Strand: Reverse

Name: nudG [H]

Synonym: mll3459

Alternate gene names: 13472989

Gene position: 2788557-2788135 (Counterclockwise)

Preceding gene: 13472990

Following gene: 13472988

Centisome position: 39.63

GC content: 65.72

Gene sequence:

>423_bases
ATGAATGATCTGGCCAATGCCGGCAAGCGCCTGCTCCTGGTCGCGGCCTGCGCGCTGGTCGATACCGACGGCCGGGTGCT
GCTCGCGCAGCGGCCCGAGGGCAAGCAGCTTGCCGGCCTGTGGGAATTTCCCGGCGGCAAGGTCGAGCCCGGCGAGACGC
CGGAACAATGCATCATCCGCGAATTGCACGAGGAGATCGGCATCGAGACCGAAATCCCGTGCCTGGCGCCGCTTACCTTC
GCCAGCCATTCCTATAACGACTTCCATCTGTTGATGCCGCTGTTTGTCTGCCGCCGCTTCCGCGGCATCGCCCAGCCCCG
GGAAGGGCAGGCGCTGAAATGGGTGCGGCCGAGAGAGATGCGCGACTATCCGATGCCGCCGGCCGACGCGCCGCTGATCC
CGTTCCTGATCGATCTGCTCTGA

Upstream 100 bases:

>100_bases
CCGGCAATGTGCCGGCGCTGGCGCTCTATCGGTCGCTCGGCTTCGAGGAAGTCTATCGCTACCATTATCGCCGGCCGCCT
GGTCATGAGTGAAATTGGGC

Downstream 100 bases:

>100_bases
GGATCCGGGACGGAGCGGGCCACGGGCCCATATCAGTCAGCGTTAATGGAAGATTTATCTCATCATGAAAAATTGATGGA
TGGCCGTGTCGTCGCGGCCG

Product: mutator protein mutT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNDLANAGKRLLLVAACALVDTDGRVLLAQRPEGKQLAGLWEFPGGKVEPGETPEQCIIRELHEEIGIETEIPCLAPLTF
ASHSYNDFHLLMPLFVCRRFRGIAQPREGQALKWVRPREMRDYPMPPADAPLIPFLIDLL

Sequences:

>Translated_140_residues
MNDLANAGKRLLLVAACALVDTDGRVLLAQRPEGKQLAGLWEFPGGKVEPGETPEQCIIRELHEEIGIETEIPCLAPLTF
ASHSYNDFHLLMPLFVCRRFRGIAQPREGQALKWVRPREMRDYPMPPADAPLIPFLIDLL
>Mature_140_residues
MNDLANAGKRLLLVAACALVDTDGRVLLAQRPEGKQLAGLWEFPGGKVEPGETPEQCIIRELHEEIGIETEIPCLAPLTF
ASHSYNDFHLLMPLFVCRRFRGIAQPREGQALKWVRPREMRDYPMPPADAPLIPFLIDLL

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=130, Percent_Identity=40.7692307692308, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786288, Length=130, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15714; Mature: 15714

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLANAGKRLLLVAACALVDTDGRVLLAQRPEGKQLAGLWEFPGGKVEPGETPEQCIIR
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHH
ELHEEIGIETEIPCLAPLTFASHSYNDFHLLMPLFVCRRFRGIAQPREGQALKWVRPREM
HHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCC
RDYPMPPADAPLIPFLIDLL
CCCCCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MNDLANAGKRLLLVAACALVDTDGRVLLAQRPEGKQLAGLWEFPGGKVEPGETPEQCIIR
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHH
ELHEEIGIETEIPCLAPLTFASHSYNDFHLLMPLFVCRRFRGIAQPREGQALKWVRPREM
HHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCC
RDYPMPPADAPLIPFLIDLL
CCCCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]