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The map label for this gene is clpB

Identifier: 13472967

GI number: 13472967

Start: 2766190

End: 2768796

Strand: Reverse

Name: clpB

Synonym: mll3429

Alternate gene names: 13472967

Gene position: 2768796-2766190 (Counterclockwise)

Preceding gene: 13472968

Following gene: 13472966

Centisome position: 39.35

GC content: 64.21

Gene sequence:

>2607_bases
ATGAACCTTGAGAAGTACTCCGAGCGCGTGCGCGGCTTCATCCAGTCCGCGCAGACGATGGCGCTCTCCCGTAATCACCA
GCAATTCACCCCCGAACACATTTTGAAGGTGCTCGTCGACGATGACGAGGGCCTGGCCGCCTCGCTGATCGAGCGCGCCG
GCGGCAATGTCCGTGACGTCAAGCTCGGCGTCGAGACGGCACTCGAGGCAATGCCAAAGGTCGAAGGCGGCAACGGCCAG
CTCTATCTGGCGCAGCCGCTGGCCAAGGTGTTCTCGACGGCCGAAGAACTGGCCAAGAAGGCCGGTGACAGCTTCGTCAC
GGTCGAGCGGCTGCTGCAGGCGCTCACCATGGAGAAGTCGGCAAAGACCGCCGACATCCTGGCCAAGGCTGGCGTCACCG
CGCAGGCGCTTAACCAGGTCATCAACGATGTCCGCAAGGGCCGCACCGCCGATTCGGCCAGTGCCGAGCAAAACTATGAC
GCGCTGAAGAAGTACGCACGTGATCTCACGGCTGATGCCCGTGCGGGCAAGCTGGACCCGGTGATCGGCCGTGACGACGA
GATCCGCCGCACCATCCAGGTGCTCTCGCGCCGAACCAAGAACAATCCGGTGCTGATCGGCGAGCCAGGCGTCGGCAAGA
CGGCGATCGCCGAAGGCCTGGCGCTGCGCATCGTCAATGGCGACGTGCCGGAATCGCTGAAGGACAAGCAACTGATGGCG
CTCGACATGGGCGCGCTGATCGCCGGCGCCAAATATCGCGGCGAATTCGAGGAGCGGCTGAAGGCTGTGCTCTCCGAAGT
GACCTCGGCCAATGGCAACATCATCCTGTTCATCGACGAGATGCACACGCTGGTCGGCGCCGGCAAGGCGGATGGCGCGA
TGGATGCGTCGAACCTGTTGAAGCCGGCGCTGGCGCGCGGTGAACTGCACTGCGTCGGCGCGACCACGCTCGATGAATAC
CGCAAACATGTCGAGAAGGATCCGGCACTGGCACGCCGCTTCCAGCCCGTCTTCGTCGACGAGCCGACGGTTGAGGACAC
CGTCTCCATCCTGCGCGGCTTGAAGGAAAAATACGAGCAGCACCACAAGGTGCGTATCTCGGACTCGGCGCTGGTGGCGG
CGGCAACGCTGTCCAACCGCTATATCGCCGACCGCTTCCTGCCGGACAAGGCGATCGACCTGGTCGACGAAGCCGCTTCG
CGGCTCAGGATGCAGGTCGATTCCAAGCCCGAGGCGCTGGATGAGATCGACCGCCGCATCATGCAGCTCAAGATCGAGCG
CGAGGCGCTGAAGGTCGAGACGGACGATGCCTCGAAGGACCGGCTCGTCCGCCTGGAGAAGGAGCTTGTCGGCCTTGAGG
AGGAATCGACCGAGATCACCGCCAAGTGGCAGGCCGAGAAGCAGAAGCTCGGGCTTGCGGCCGACTTGAAGAAGCAGCTC
GACGAGGCACGCAACGAGCTCGCCATTGCCCAGCGCAAGGGCGAGTTCCAGCGCGCCGGCGAGCTCGCCTATGGCAAGAT
CCCGGAACTGGAAAAGAAGCTGAAGGAAGCCGAAGCCCAGGACGGCAAGGCCGGCATGGTCGAGGAAGTGGTCACCCCCG
ACCACGTCGCCCATATCGTCTCGCGCTGGACCGGCATTCCAGTCGACAAGATGCTGCAGGGCGAGCGCGACAAGTTGCTG
CGCATGGAAGACGAGATCGGCAAGCGGGTTGTTGGCCAGGGCGAGGCGGTGCAGGCCGTTTCCAAGGCGGTGCGGCGCGC
CCGTGCCGGCCTGCAGGATCCGAACCGGCCGATCGGCTCGTTCATCTTCCTGGGGCCGACGGGCGTCGGCAAGACCGAAC
TGACCAAGGCGCTGGCAAGCTTCCTGTTCGACGACGACAGCGCCATGGTGCGCATCGACATGTCGGAGTTCATGGAGAAG
CACTCGGTCGCCCGGCTGATCGGCGCGCCTCCCGGCTATGTCGGCTATGAGGAGGGTGGTGCGCTGACCGAAGCGGTGCG
GCGCCGGCCCTATCAGGTCGTGCTGTTCGACGAAATCGAGAAGGCGCATCCCGATGTCTTCAACGTGCTCTTGCAGGTGC
TGGACGACGGCCGGCTCACCGACGGGCAGGGCCGCACGGTCGATTTCCGCAACACGCTGATCATCATGACGTCGAACCTC
GGCGCCGAATATCTTGTCAATCTCGGCGAAGACCAGGATGTCGATGCCGTGCGCGACGAGGTGATGGGCGTGGTCAGGGC
ATCGTTCCGGCCGGAATTCCTCAACCGCGTCGACGAGGTGATCCTGTTCCACCGGCTGCGCCGCAAGGACATGGACCGCA
TCGTCGAGATCCAGTTCAAGCGGCTGGAAAGCCTGCTCGTCGATCGCAAGATCACGCTGTCGCTGGATCACGAGGCAATC
GAGTGGCTGGCGGCCAAGGGCTACGACCCGGCCTATGGCGCGCGGCCGTTGAAGCGGGTGATGCAGAAGGAACTGCAGGA
TCCGCTGGCGGAGAAGATCCTGCTCGGCGAGATTCTCGACGGTTCGACCGTCAAGGTCACGTCCGGTTCCGACCGGCTGA
ACTTCCGCTCGAAGCCGACGGTCGTCGCGACCGAAGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
ACCATATCTCGGCTGAACAGGACCCGGCTCGAATGGGCGGGTCCGTCACCGCAATCTGATCCGGTGCCGCAAAGCGGGCC
GGTGATGGAAGGAGACAGAT

Downstream 100 bases:

>100_bases
TTTTCAACGCCGCGCGTCCAGGCTGGGCGCGCGGCGTTTTCATAGTGATTTGGGGGGCGGATGACGCTGGACGACTACAA
CGGCTTCTGCGCCTCATTGC

Product: endopeptidase Clp ATP-binding chain B, clpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 868; Mature: 868

Protein sequence:

>868_residues
MNLEKYSERVRGFIQSAQTMALSRNHQQFTPEHILKVLVDDDEGLAASLIERAGGNVRDVKLGVETALEAMPKVEGGNGQ
LYLAQPLAKVFSTAEELAKKAGDSFVTVERLLQALTMEKSAKTADILAKAGVTAQALNQVINDVRKGRTADSASAEQNYD
ALKKYARDLTADARAGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
LDMGALIAGAKYRGEFEERLKAVLSEVTSANGNIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDPALARRFQPVFVDEPTVEDTVSILRGLKEKYEQHHKVRISDSALVAAATLSNRYIADRFLPDKAIDLVDEAAS
RLRMQVDSKPEALDEIDRRIMQLKIEREALKVETDDASKDRLVRLEKELVGLEEESTEITAKWQAEKQKLGLAADLKKQL
DEARNELAIAQRKGEFQRAGELAYGKIPELEKKLKEAEAQDGKAGMVEEVVTPDHVAHIVSRWTGIPVDKMLQGERDKLL
RMEDEIGKRVVGQGEAVQAVSKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFDDDSAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNL
GAEYLVNLGEDQDVDAVRDEVMGVVRASFRPEFLNRVDEVILFHRLRRKDMDRIVEIQFKRLESLLVDRKITLSLDHEAI
EWLAAKGYDPAYGARPLKRVMQKELQDPLAEKILLGEILDGSTVKVTSGSDRLNFRSKPTVVATEAAA

Sequences:

>Translated_868_residues
MNLEKYSERVRGFIQSAQTMALSRNHQQFTPEHILKVLVDDDEGLAASLIERAGGNVRDVKLGVETALEAMPKVEGGNGQ
LYLAQPLAKVFSTAEELAKKAGDSFVTVERLLQALTMEKSAKTADILAKAGVTAQALNQVINDVRKGRTADSASAEQNYD
ALKKYARDLTADARAGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
LDMGALIAGAKYRGEFEERLKAVLSEVTSANGNIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDPALARRFQPVFVDEPTVEDTVSILRGLKEKYEQHHKVRISDSALVAAATLSNRYIADRFLPDKAIDLVDEAAS
RLRMQVDSKPEALDEIDRRIMQLKIEREALKVETDDASKDRLVRLEKELVGLEEESTEITAKWQAEKQKLGLAADLKKQL
DEARNELAIAQRKGEFQRAGELAYGKIPELEKKLKEAEAQDGKAGMVEEVVTPDHVAHIVSRWTGIPVDKMLQGERDKLL
RMEDEIGKRVVGQGEAVQAVSKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFDDDSAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNL
GAEYLVNLGEDQDVDAVRDEVMGVVRASFRPEFLNRVDEVILFHRLRRKDMDRIVEIQFKRLESLLVDRKITLSLDHEAI
EWLAAKGYDPAYGARPLKRVMQKELQDPLAEKILLGEILDGSTVKVTSGSDRLNFRSKPTVVATEAAA
>Mature_868_residues
MNLEKYSERVRGFIQSAQTMALSRNHQQFTPEHILKVLVDDDEGLAASLIERAGGNVRDVKLGVETALEAMPKVEGGNGQ
LYLAQPLAKVFSTAEELAKKAGDSFVTVERLLQALTMEKSAKTADILAKAGVTAQALNQVINDVRKGRTADSASAEQNYD
ALKKYARDLTADARAGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
LDMGALIAGAKYRGEFEERLKAVLSEVTSANGNIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDPALARRFQPVFVDEPTVEDTVSILRGLKEKYEQHHKVRISDSALVAAATLSNRYIADRFLPDKAIDLVDEAAS
RLRMQVDSKPEALDEIDRRIMQLKIEREALKVETDDASKDRLVRLEKELVGLEEESTEITAKWQAEKQKLGLAADLKKQL
DEARNELAIAQRKGEFQRAGELAYGKIPELEKKLKEAEAQDGKAGMVEEVVTPDHVAHIVSRWTGIPVDKMLQGERDKLL
RMEDEIGKRVVGQGEAVQAVSKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFDDDSAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNL
GAEYLVNLGEDQDVDAVRDEVMGVVRASFRPEFLNRVDEVILFHRLRRKDMDRIVEIQFKRLESLLVDRKITLSLDHEAI
EWLAAKGYDPAYGARPLKRVMQKELQDPLAEKILLGEILDGSTVKVTSGSDRLNFRSKPTVVATEAAA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family

Homologues:

Organism=Homo sapiens, GI13540606, Length=453, Percent_Identity=31.3465783664459, Blast_Score=205, Evalue=2e-52,
Organism=Escherichia coli, GI1788943, Length=854, Percent_Identity=58.07962529274, Blast_Score=1014, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=409, Percent_Identity=41.5647921760391, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=699, Percent_Identity=56.6523605150215, Blast_Score=801, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=859, Percent_Identity=44.1210710128056, Blast_Score=688, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CLPB_RHILO (Q98G96)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104534.1
- ProteinModelPortal:   Q98G96
- GeneID:   1227195
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll3429
- NMPDR:   fig|266835.1.peg.2638
- HOGENOM:   HBG413133
- OMA:   YITERRL
- ProtClustDB:   CLSK863757
- GO:   GO:0005737
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- Gene3D:   G3DSA:1.10.1780.10
- PRINTS:   PR00300
- SMART:   SM00382
- TIGRFAMs:   TIGR03346

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small

EC number: NA

Molecular weight: Translated: 95980; Mature: 95980

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00870 CLPAB_1; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEKYSERVRGFIQSAQTMALSRNHQQFTPEHILKVLVDDDEGLAASLIERAGGNVRDV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEEE
KLGVETALEAMPKVEGGNGQLYLAQPLAKVFSTAEELAKKAGDSFVTVERLLQALTMEKS
EHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AKTADILAKAGVTAQALNQVINDVRKGRTADSASAEQNYDALKKYARDLTADARAGKLDP
CHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCC
VIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCCCCCHHHH
LDMGALIAGAKYRGEFEERLKAVLSEVTSANGNIILFIDEMHTLVGAGKADGAMDASNLL
HHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLDEYRKHVEKDPALARRFQPVFVDEPTVEDTVSILRGLKEKYEQ
HHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHKVRISDSALVAAATLSNRYIADRFLPDKAIDLVDEAASRLRMQVDSKPEALDEIDRRI
HCCEEECCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQLKIEREALKVETDDASKDRLVRLEKELVGLEEESTEITAKWQAEKQKLGLAADLKKQL
HHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHHHHH
DEARNELAIAQRKGEFQRAGELAYGKIPELEKKLKEAEAQDGKAGMVEEVVTPDHVAHIV
HHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHH
SRWTGIPVDKMLQGERDKLLRMEDEIGKRVVGQGEAVQAVSKAVRRARAGLQDPNRPIGS
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELTKALASFLFDDDSAMVRIDMSEFMEKHSVARLIGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
ALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNL
HHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GAEYLVNLGEDQDVDAVRDEVMGVVRASFRPEFLNRVDEVILFHRLRRKDMDRIVEIQFK
CHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLESLLVDRKITLSLDHEAIEWLAAKGYDPAYGARPLKRVMQKELQDPLAEKILLGEILD
HHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GSTVKVTSGSDRLNFRSKPTVVATEAAA
CCEEEEECCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure
MNLEKYSERVRGFIQSAQTMALSRNHQQFTPEHILKVLVDDDEGLAASLIERAGGNVRDV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEEE
KLGVETALEAMPKVEGGNGQLYLAQPLAKVFSTAEELAKKAGDSFVTVERLLQALTMEKS
EHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AKTADILAKAGVTAQALNQVINDVRKGRTADSASAEQNYDALKKYARDLTADARAGKLDP
CHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCC
VIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCCCCCHHHH
LDMGALIAGAKYRGEFEERLKAVLSEVTSANGNIILFIDEMHTLVGAGKADGAMDASNLL
HHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLDEYRKHVEKDPALARRFQPVFVDEPTVEDTVSILRGLKEKYEQ
HHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHKVRISDSALVAAATLSNRYIADRFLPDKAIDLVDEAASRLRMQVDSKPEALDEIDRRI
HCCEEECCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQLKIEREALKVETDDASKDRLVRLEKELVGLEEESTEITAKWQAEKQKLGLAADLKKQL
HHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHHHHH
DEARNELAIAQRKGEFQRAGELAYGKIPELEKKLKEAEAQDGKAGMVEEVVTPDHVAHIV
HHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHH
SRWTGIPVDKMLQGERDKLLRMEDEIGKRVVGQGEAVQAVSKAVRRARAGLQDPNRPIGS
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELTKALASFLFDDDSAMVRIDMSEFMEKHSVARLIGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
ALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNL
HHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GAEYLVNLGEDQDVDAVRDEVMGVVRASFRPEFLNRVDEVILFHRLRRKDMDRIVEIQFK
CHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLESLLVDRKITLSLDHEAIEWLAAKGYDPAYGARPLKRVMQKELQDPLAEKILLGEILD
HHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GSTVKVTSGSDRLNFRSKPTVVATEAAA
CCEEEEECCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968