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The map label for this gene is lacF [H]

Identifier: 13472933

GI number: 13472933

Start: 2718835

End: 2719896

Strand: Reverse

Name: lacF [H]

Synonym: mll3383

Alternate gene names: 13472933

Gene position: 2719896-2718835 (Counterclockwise)

Preceding gene: 13472934

Following gene: 13472932

Centisome position: 38.66

GC content: 58.47

Gene sequence:

>1062_bases
ATGACCGCTGTTTCAAGCACGCTGCTGACACCACGCCTTACCGCGGTTGTTGCCCACAACTGGAAACTCGCCATCGCTGT
CGCTGTCGTCGTGTCGGCCATATCAATGGCGGGCTTGCCGGCGGCTGTCTCCTTCTGGGTGGTGGGCGCCGCGGCGGCGT
TGGTCGCGGCCGCATTTACCGTCAACGCGTATCGCCGCCACTACTTCGGCGCCCTGCTGGTCGCTCCGGCAATCGCCGTT
CTGTTTGTGATGAATATCTTCCCCCTGCTGTGGTCGCTGGGCCTTTCGTTCTTCGCCTACCAGGCAAACCAGCAGACGAT
CCGCTTCGTCGGACTCGGGAACTACGTCCGGATCCTTACCAACGATCTCGCTGCTCACGCGACTTGGGGCGCGCTGATCA
ATACCGCCATGTTCGTCGTGTTCACCGTCTCCGCGCAGATGATCGTCGGCTTTCTGCTGGCCATCCTGTTCGCCAAGCAA
TTTCCGCTGCGCAAGTATTTGTTGATCCTGGTGCTGACACCGATGATGCTTTCGGTTGTCGCCTCTGGCGTGTTCTTCAC
CTACTACTATGACCCGACATTCGGGATTCTCAGCTACGTCATCAATTCGATCTCCGGCAACCAGTTCATCCTGATGAGCA
ACAAAGTCGGTGCCGTGGCGGGAATCGTTTTCGCCGACGCATGGATGTGGTCGCCCTTCGTCATGCTCCTTGTGCTGGCG
GGCCTCGTCTCGGTGCCGAAATACCTTTACGAGGCCGCTGCCATCGACCGTATTTCCAGCTGGCGGCAATTCTGGATGAT
CACCTTCCCCTACATCCGCGGCCTTCTGATGTTGGCCCTTCTCTTCCGCACCATCGAGGCATTCAAGCTGGCGGATCTCG
TCATCCTCCTCACCAAGGGCGGCAACGACACACTGACGATCTCCTATCACTTGATCCGCATCGCCAACGAGCAGAACAAG
ACGAGTGAGGGCGCGGCGATCTCCTATCTGATGCTGTTCATGGTGATCGTTCTCACCAACCTCTACCTGTACCTCGCAAA
CCGCCGTACGAAGGGAGCCTGA

Upstream 100 bases:

>100_bases
AACGCTGGCCTTATCCAGTAACCTTCCGACATAGCTGCGGGGAGCGGGCAAAGCCGCTCCCCATCATTGCCACGCCAGGC
GCTCCATATTTCGGACTCCC

Downstream 100 bases:

>100_bases
CCCGTGGCCGAATCGATATTGGGAAAGCTCGGCTTCGGCAGGGCCAGCGGAGTAGACAAGGCCGGCTGGGGGCGGACGCT
CGCCGTGGCCATCGTCGCCT

Product: ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTAVSSTLLTPRLTAVVAHNWKLAIAVAVVVSAISMAGLPAAVSFWVVGAAAALVAAAFTVNAYRRHYFGALLVAPAIAV
LFVMNIFPLLWSLGLSFFAYQANQQTIRFVGLGNYVRILTNDLAAHATWGALINTAMFVVFTVSAQMIVGFLLAILFAKQ
FPLRKYLLILVLTPMMLSVVASGVFFTYYYDPTFGILSYVINSISGNQFILMSNKVGAVAGIVFADAWMWSPFVMLLVLA
GLVSVPKYLYEAAAIDRISSWRQFWMITFPYIRGLLMLALLFRTIEAFKLADLVILLTKGGNDTLTISYHLIRIANEQNK
TSEGAAISYLMLFMVIVLTNLYLYLANRRTKGA

Sequences:

>Translated_353_residues
MTAVSSTLLTPRLTAVVAHNWKLAIAVAVVVSAISMAGLPAAVSFWVVGAAAALVAAAFTVNAYRRHYFGALLVAPAIAV
LFVMNIFPLLWSLGLSFFAYQANQQTIRFVGLGNYVRILTNDLAAHATWGALINTAMFVVFTVSAQMIVGFLLAILFAKQ
FPLRKYLLILVLTPMMLSVVASGVFFTYYYDPTFGILSYVINSISGNQFILMSNKVGAVAGIVFADAWMWSPFVMLLVLA
GLVSVPKYLYEAAAIDRISSWRQFWMITFPYIRGLLMLALLFRTIEAFKLADLVILLTKGGNDTLTISYHLIRIANEQNK
TSEGAAISYLMLFMVIVLTNLYLYLANRRTKGA
>Mature_352_residues
TAVSSTLLTPRLTAVVAHNWKLAIAVAVVVSAISMAGLPAAVSFWVVGAAAALVAAAFTVNAYRRHYFGALLVAPAIAVL
FVMNIFPLLWSLGLSFFAYQANQQTIRFVGLGNYVRILTNDLAAHATWGALINTAMFVVFTVSAQMIVGFLLAILFAKQF
PLRKYLLILVLTPMMLSVVASGVFFTYYYDPTFGILSYVINSISGNQFILMSNKVGAVAGIVFADAWMWSPFVMLLVLAG
LVSVPKYLYEAAAIDRISSWRQFWMITFPYIRGLLMLALLFRTIEAFKLADLVILLTKGGNDTLTISYHLIRIANEQNKT
SEGAAISYLMLFMVIVLTNLYLYLANRRTKGA

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=261, Percent_Identity=28.3524904214559, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789861, Length=282, Percent_Identity=26.241134751773, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38823; Mature: 38692

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVSSTLLTPRLTAVVAHNWKLAIAVAVVVSAISMAGLPAAVSFWVVGAAAALVAAAFT
CCCCHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VNAYRRHYFGALLVAPAIAVLFVMNIFPLLWSLGLSFFAYQANQQTIRFVGLGNYVRILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHH
NDLAAHATWGALINTAMFVVFTVSAQMIVGFLLAILFAKQFPLRKYLLILVLTPMMLSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASGVFFTYYYDPTFGILSYVINSISGNQFILMSNKVGAVAGIVFADAWMWSPFVMLLVLA
HCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GLVSVPKYLYEAAAIDRISSWRQFWMITFPYIRGLLMLALLFRTIEAFKLADLVILLTKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
GNDTLTISYHLIRIANEQNKTSEGAAISYLMLFMVIVLTNLYLYLANRRTKGA
CCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAVSSTLLTPRLTAVVAHNWKLAIAVAVVVSAISMAGLPAAVSFWVVGAAAALVAAAFT
CCCHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VNAYRRHYFGALLVAPAIAVLFVMNIFPLLWSLGLSFFAYQANQQTIRFVGLGNYVRILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHH
NDLAAHATWGALINTAMFVVFTVSAQMIVGFLLAILFAKQFPLRKYLLILVLTPMMLSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASGVFFTYYYDPTFGILSYVINSISGNQFILMSNKVGAVAGIVFADAWMWSPFVMLLVLA
HCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GLVSVPKYLYEAAAIDRISSWRQFWMITFPYIRGLLMLALLFRTIEAFKLADLVILLTKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
GNDTLTISYHLIRIANEQNKTSEGAAISYLMLFMVIVLTNLYLYLANRRTKGA
CCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]