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The map label for this gene is blaSE [H]

Identifier: 13472876

GI number: 13472876

Start: 2662643

End: 2663737

Strand: Reverse

Name: blaSE [H]

Synonym: mll3306

Alternate gene names: 13472876

Gene position: 2663737-2662643 (Counterclockwise)

Preceding gene: 13472878

Following gene: 13472875

Centisome position: 37.86

GC content: 61.19

Gene sequence:

>1095_bases
ATGACAAAACTGACAAATGCTATCTTTGCGTCCGCATTGCTTTCCACCGCAATGTGGACGGCCCCGGTTTTCGCCGCCGA
CCCTGGTTCCGCCAGTGCCGGCAATGGCGAAAGCATGCGGGACGTTACTTCAGGCGACTTCAAGGCCGGTCGGGCAAAAC
CGATCACGACTCCAGAGCTTACTGATGAAGACAGCCGCGCCGCGCCGCTCACCGACGAGAAGGCGGCTGTCAAATCCTAT
GGCATCGTCGGGCGTTCCGCCGATGGCAAGGAGATCAAGATCGAACCAAGCGAAGCGCTGCGCGAGCTCATCATCAAGGA
ACTGAACGCGCCGGCCAATGGCGCCGACGGGGCTGAGCGCAAGACCGAGGACCCCGGGCTCGGCGAAGGCGAGGCCGGGC
GCCAGGTTTTCGGCCCCGACGATCGCGAGCAGGTCAGGAACACCAAGACCTATCCGTTCTCGGCCATCGGCTATCTGGAA
GCCAAATCGGCGAAGACGGGCAGCTATGGCAGCTGTTCTGCAACGCTGATCGGCCCGCGCACGGTGCTCACCGCGGCGCA
TTGCCTCTACAGCCATGAGGACAAGGACTGGCTCTCCGAGTATCTGTTCGTGCCAGGCCTCAACGGCAGCACTGCCGACG
ACGCACCATTCGGTGCCTTCACCTATGAAAGCGCCTATGTGCTGCAAGGCTTCATCGACAACTACCAGGGCTATTACGGC
TCGGTGATCCCGTGGGATCTTGGCATCATCACGCTGAAGCAGGATGTCGGCACCAACCTCGGCTGGCTGGGCTACGCCAA
TTATGACGACCTCGGCGACTTCACCGCCAACCTCGTCGGCTATCCCGGGGACAAGCCGATGGGCACGATGTGGAAGGCCA
GCTGCGAAGTGCATGCCGAGAACATCGCCCCGGAATATTTCCAGTATGATTGCGATACGTTCCCGGGGTCGAGCGGCAGC
TCGGTCTATGCCTATGACACCAAGTCCAAGCAGCGCATCATCACCGGCGTCAACGTCGCGGAAAGCCCCGACGCGAACAC
CGCCGTGCGCCTGAACGCGGCCAACGTCCAGTGGATCAACAGCCTGTACAAATAG

Upstream 100 bases:

>100_bases
GGAATGCCAGCGAGCAGACTCATTTTTCGGCGTCACCACGATCTCGACAATATTTCTCTATTTTGATCCAGTCCTTGCTG
ACTTTTGGGAGAGTCTCACC

Downstream 100 bases:

>100_bases
GCGCTGCGCGTTCGCGGTGAAGGCAAAGGCGGTGGGTCAATCCCGCCGCCTTTTTCGTGCCGATCCTTCCCTCATGGCTT
CCCTTGCGCGAGGCCGGCGC

Product: glutamyl endopeptidase

Products: NA

Alternate protein names: Glutamate-specific endopeptidase; GSE [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTKLTNAIFASALLSTAMWTAPVFAADPGSASAGNGESMRDVTSGDFKAGRAKPITTPELTDEDSRAAPLTDEKAAVKSY
GIVGRSADGKEIKIEPSEALRELIIKELNAPANGADGAERKTEDPGLGEGEAGRQVFGPDDREQVRNTKTYPFSAIGYLE
AKSAKTGSYGSCSATLIGPRTVLTAAHCLYSHEDKDWLSEYLFVPGLNGSTADDAPFGAFTYESAYVLQGFIDNYQGYYG
SVIPWDLGIITLKQDVGTNLGWLGYANYDDLGDFTANLVGYPGDKPMGTMWKASCEVHAENIAPEYFQYDCDTFPGSSGS
SVYAYDTKSKQRIITGVNVAESPDANTAVRLNAANVQWINSLYK

Sequences:

>Translated_364_residues
MTKLTNAIFASALLSTAMWTAPVFAADPGSASAGNGESMRDVTSGDFKAGRAKPITTPELTDEDSRAAPLTDEKAAVKSY
GIVGRSADGKEIKIEPSEALRELIIKELNAPANGADGAERKTEDPGLGEGEAGRQVFGPDDREQVRNTKTYPFSAIGYLE
AKSAKTGSYGSCSATLIGPRTVLTAAHCLYSHEDKDWLSEYLFVPGLNGSTADDAPFGAFTYESAYVLQGFIDNYQGYYG
SVIPWDLGIITLKQDVGTNLGWLGYANYDDLGDFTANLVGYPGDKPMGTMWKASCEVHAENIAPEYFQYDCDTFPGSSGS
SVYAYDTKSKQRIITGVNVAESPDANTAVRLNAANVQWINSLYK
>Mature_363_residues
TKLTNAIFASALLSTAMWTAPVFAADPGSASAGNGESMRDVTSGDFKAGRAKPITTPELTDEDSRAAPLTDEKAAVKSYG
IVGRSADGKEIKIEPSEALRELIIKELNAPANGADGAERKTEDPGLGEGEAGRQVFGPDDREQVRNTKTYPFSAIGYLEA
KSAKTGSYGSCSATLIGPRTVLTAAHCLYSHEDKDWLSEYLFVPGLNGSTADDAPFGAFTYESAYVLQGFIDNYQGYYGS
VIPWDLGIITLKQDVGTNLGWLGYANYDDLGDFTANLVGYPGDKPMGTMWKASCEVHAENIAPEYFQYDCDTFPGSSGSS
VYAYDTKSKQRIITGVNVAESPDANTAVRLNAANVQWINSLYK

Specific function: Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues, with a strong preference for Glu [H]

COG id: COG3591

COG function: function code E; V8-like Glu-specific endopeptidase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: =3.4.21.19 [H]

Molecular weight: Translated: 39034; Mature: 38903

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00134 TRYPSIN_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTNAIFASALLSTAMWTAPVFAADPGSASAGNGESMRDVTSGDFKAGRAKPITTPEL
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
TDEDSRAAPLTDEKAAVKSYGIVGRSADGKEIKIEPSEALRELIIKELNAPANGADGAER
CCCCCCCCCCCCHHHHHHHHCCEECCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCC
KTEDPGLGEGEAGRQVFGPDDREQVRNTKTYPFSAIGYLEAKSAKTGSYGSCSATLIGPR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCH
TVLTAAHCLYSHEDKDWLSEYLFVPGLNGSTADDAPFGAFTYESAYVLQGFIDNYQGYYG
HHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCC
SVIPWDLGIITLKQDVGTNLGWLGYANYDDLGDFTANLVGYPGDKPMGTMWKASCEVHAE
CCCEECCEEEEEEHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCEEECCEEEEHH
NIAPEYFQYDCDTFPGSSGSSVYAYDTKSKQRIITGVNVAESPDANTAVRLNAANVQWIN
HCCHHHHEECCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHH
SLYK
HHCC
>Mature Secondary Structure 
TKLTNAIFASALLSTAMWTAPVFAADPGSASAGNGESMRDVTSGDFKAGRAKPITTPEL
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
TDEDSRAAPLTDEKAAVKSYGIVGRSADGKEIKIEPSEALRELIIKELNAPANGADGAER
CCCCCCCCCCCCHHHHHHHHCCEECCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCC
KTEDPGLGEGEAGRQVFGPDDREQVRNTKTYPFSAIGYLEAKSAKTGSYGSCSATLIGPR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCH
TVLTAAHCLYSHEDKDWLSEYLFVPGLNGSTADDAPFGAFTYESAYVLQGFIDNYQGYYG
HHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCC
SVIPWDLGIITLKQDVGTNLGWLGYANYDDLGDFTANLVGYPGDKPMGTMWKASCEVHAE
CCCEECCEEEEEEHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCEEECCEEEEHH
NIAPEYFQYDCDTFPGSSGSSVYAYDTKSKQRIITGVNVAESPDANTAVRLNAANVQWIN
HCCHHHHEECCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHH
SLYK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1429718; 1346764 [H]