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The map label for this gene is cdd [H]

Identifier: 13472756

GI number: 13472756

Start: 2529685

End: 2530077

Strand: Direct

Name: cdd [H]

Synonym: mlr3158

Alternate gene names: 13472756

Gene position: 2529685-2530077 (Clockwise)

Preceding gene: 13472755

Following gene: 13472757

Centisome position: 35.95

GC content: 63.1

Gene sequence:

>393_bases
ATGTCGCATGATCTGTTCGAAGCGGCCAGGACCGCCATGGCCAAGGCCTATGCGCCCTACTCGAAATTTCCGGTGGGCGC
CGCCTTGCGCACCGAGGACGGACGCGTCTTCACCGGTGCCAACATCGAAGTCGCCTCCTATCCTGAAGGCTGGTGCGCCG
AGACCACCGCGCTCGGCCACTACATCATGGGCGGCGGCGGCAAGATCGTCGAAATCGCTGTCCTTGCCGAACGCATGGCC
AAATGCTCGCCTTGCGGCGGCTGCCGCCAGCGGCTGGCCGAATTCTGCCAACCGGACACGAAACTCTACCTCTGCGACAA
TACGGGCGTGGCCGAGACCGTAACCATGGGCGACATGCTGCCCTATGGTTTCCGCGGCGACATCCTGAAATGA

Upstream 100 bases:

>100_bases
TCGCCTGAATCCGTTTCGACGCGACGCGCTTTAAGGGCCGACGGCCCGGCGCGTGCCTCGCGCCGGGTTTTGGACACGAT
CATCGGAGAGAACAACAGAA

Downstream 100 bases:

>100_bases
GGAATTGGCTCAAATGAAGAGTGGGCTGCAATGACCGAAAAGGCGGTGGACCATCTGATCGAAAGGCTGGACGGCCTGGC
GCCGTCGACGGCGCTGGTGC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MSHDLFEAARTAMAKAYAPYSKFPVGAALRTEDGRVFTGANIEVASYPEGWCAETTALGHYIMGGGGKIVEIAVLAERMA
KCSPCGGCRQRLAEFCQPDTKLYLCDNTGVAETVTMGDMLPYGFRGDILK

Sequences:

>Translated_130_residues
MSHDLFEAARTAMAKAYAPYSKFPVGAALRTEDGRVFTGANIEVASYPEGWCAETTALGHYIMGGGGKIVEIAVLAERMA
KCSPCGGCRQRLAEFCQPDTKLYLCDNTGVAETVTMGDMLPYGFRGDILK
>Mature_129_residues
SHDLFEAARTAMAKAYAPYSKFPVGAALRTEDGRVFTGANIEVASYPEGWCAETTALGHYIMGGGGKIVEIAVLAERMAK
CSPCGGCRQRLAEFCQPDTKLYLCDNTGVAETVTMGDMLPYGFRGDILK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=129, Percent_Identity=38.7596899224806, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=126, Percent_Identity=42.0634920634921, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17551074, Length=122, Percent_Identity=45.0819672131148, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=124, Percent_Identity=39.5161290322581, Blast_Score=82, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582741, Length=127, Percent_Identity=40.9448818897638, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920920, Length=104, Percent_Identity=42.3076923076923, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24582744, Length=103, Percent_Identity=45.6310679611651, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13982; Mature: 13851

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDLFEAARTAMAKAYAPYSKFPVGAALRTEDGRVFTGANIEVASYPEGWCAETTALGH
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEECCCEEECCCCCCCCCHHHHHCC
YIMGGGGKIVEIAVLAERMAKCSPCGGCRQRLAEFCQPDTKLYLCDNTGVAETVTMGDML
EEECCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCC
PYGFRGDILK
CCCCCCCCCC
>Mature Secondary Structure 
SHDLFEAARTAMAKAYAPYSKFPVGAALRTEDGRVFTGANIEVASYPEGWCAETTALGH
CCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEECCCEEECCCCCCCCCHHHHHCC
YIMGGGGKIVEIAVLAERMAKCSPCGGCRQRLAEFCQPDTKLYLCDNTGVAETVTMGDML
EEECCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCC
PYGFRGDILK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]