BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is bdhA [H]

Identifier: 13472632

GI number: 13472632

Start: 2400011

End: 2400766

Strand: Reverse

Name: bdhA [H]

Synonym: mll2989

Alternate gene names: 13472632

Gene position: 2400766-2400011 (Counterclockwise)

Preceding gene: 13472633

Following gene: 13472629

Centisome position: 34.12

GC content: 66.14

Gene sequence:

>756_bases
ATGACCGAAGAAAGAACCGCCATCGTCACCGGTGCCGGCACAGGCATCGGCAAGAGCGTCGCCACGGCGCTGCTCAAGGC
CGGCTGGAACACGGTGTTCTGCGGCCGCCGCAAAGCGGTGCTCGATGCCGCGATCGTCGAGGCCGGCCGGACCGAGGCCA
AGGCATTGGCGGTTGCCTGCGACATCAGCAAGGCCGGCGAGGTCGACGATCTGTTCGAGACGGTGGCGGAAGCCTTCGGC
CGCGTCGACCTGCTCTTCAACAATGCCGGCATGGGCTACAAGTCGACGCCGATCGACGAGATCCCGGTCGAAGTGTGGAA
CGATATTGTCGGCGTCAATCTCACCGGTTCGTTCCTGTGCGCCCGCGCCGCCTTTGGCGCCATGCGCAAGCAACGACCGA
TGGGCGGGCGCATCATCAACAACGGCTCGGTGTCGGCCTATGCGCCGCGCCCGGGCTCGGTGCCCTATACGGCGACCAAG
CATGCCATCACCGGCCTGACCAAGACGCTGGCGCTCGACGGCCGGCCCTACGACATCGCCTGCGGCCAGATCGACATCGG
CAATGCGCTGACCGACATGGCGCAGCCGATGACCGTCGGCGTGCCGCAGGCCAATGGCTCGATCGCCGCCGAAGCAGTGA
TGGATGTCCAGCACGTTGCCGATGCCGTCGTCCACATGGCCAGCCTGCCGCTCGAGGCGAACGTGCTGTTCATGACCGTG
ATGGCGACCAAGATGCCGTTCGTCGGGCGTGGGTGA

Upstream 100 bases:

>100_bases
AGGTCCGCTTGCCATCGCTGCCGTCATTTGCGATTCCTTCTGCCGAGCCAAATCCTGAAGATCAGTCGGGCACGCTCGGC
GCTGCCGGAGGACATCAGCC

Downstream 100 bases:

>100_bases
GCAGCGGACGCTTGCAGGGCCTCCGCCGCCGGCTCATTTGCCCGCCAGCGGCGCACCGGGCTTGAACAGCAGAATGGGCC
TGATCTCGTAGACGGCGGTC

Product: oxidoreductase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTEERTAIVTGAGTGIGKSVATALLKAGWNTVFCGRRKAVLDAAIVEAGRTEAKALAVACDISKAGEVDDLFETVAEAFG
RVDLLFNNAGMGYKSTPIDEIPVEVWNDIVGVNLTGSFLCARAAFGAMRKQRPMGGRIINNGSVSAYAPRPGSVPYTATK
HAITGLTKTLALDGRPYDIACGQIDIGNALTDMAQPMTVGVPQANGSIAAEAVMDVQHVADAVVHMASLPLEANVLFMTV
MATKMPFVGRG

Sequences:

>Translated_251_residues
MTEERTAIVTGAGTGIGKSVATALLKAGWNTVFCGRRKAVLDAAIVEAGRTEAKALAVACDISKAGEVDDLFETVAEAFG
RVDLLFNNAGMGYKSTPIDEIPVEVWNDIVGVNLTGSFLCARAAFGAMRKQRPMGGRIINNGSVSAYAPRPGSVPYTATK
HAITGLTKTLALDGRPYDIACGQIDIGNALTDMAQPMTVGVPQANGSIAAEAVMDVQHVADAVVHMASLPLEANVLFMTV
MATKMPFVGRG
>Mature_250_residues
TEERTAIVTGAGTGIGKSVATALLKAGWNTVFCGRRKAVLDAAIVEAGRTEAKALAVACDISKAGEVDDLFETVAEAFGR
VDLLFNNAGMGYKSTPIDEIPVEVWNDIVGVNLTGSFLCARAAFGAMRKQRPMGGRIINNGSVSAYAPRPGSVPYTATKH
AITGLTKTLALDGRPYDIACGQIDIGNALTDMAQPMTVGVPQANGSIAAEAVMDVQHVADAVVHMASLPLEANVLFMTVM
ATKMPFVGRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=203, Percent_Identity=34.4827586206897, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI19923817, Length=191, Percent_Identity=31.9371727748691, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=29.9145299145299, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI32483357, Length=175, Percent_Identity=29.7142857142857, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI31542939, Length=176, Percent_Identity=32.3863636363636, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI209862901, Length=196, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI19923983, Length=196, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=154, Percent_Identity=29.8701298701299, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=32, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40254992, Length=194, Percent_Identity=28.8659793814433, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=26.4864864864865, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.0155440414508, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=29.5, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4503817, Length=177, Percent_Identity=28.8135593220339, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7706318, Length=164, Percent_Identity=31.0975609756098, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI15277342, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=173, Percent_Identity=35.8381502890173, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790717, Length=193, Percent_Identity=27.4611398963731, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787335, Length=235, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI87082160, Length=229, Percent_Identity=32.3144104803493, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=171, Percent_Identity=33.9181286549708, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789057, Length=202, Percent_Identity=32.1782178217822, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789208, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786812, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=24.1935483870968, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=28.8659793814433, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=219, Percent_Identity=30.5936073059361, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=192, Percent_Identity=27.6041666666667, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=206, Percent_Identity=27.6699029126214, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=211, Percent_Identity=30.8056872037915, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71997099, Length=280, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=174, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=226, Percent_Identity=29.2035398230088, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=174, Percent_Identity=29.3103448275862, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=194, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=23.6641221374046, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=177, Percent_Identity=28.8135593220339, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=31.9371727748691, Blast_Score=85, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=172, Percent_Identity=27.3255813953488, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007236, Length=248, Percent_Identity=29.4354838709677, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571387, Length=253, Percent_Identity=28.4584980237154, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=33.8624338624339, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI23397609, Length=233, Percent_Identity=28.755364806867, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=32.5842696629214, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355319, Length=175, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281364494, Length=245, Percent_Identity=25.3061224489796, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=174, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161076933, Length=181, Percent_Identity=30.939226519337, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=30.939226519337, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574402, Length=189, Percent_Identity=30.6878306878307, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=30.6878306878307, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=171, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007234, Length=259, Percent_Identity=28.1853281853282, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648944, Length=195, Percent_Identity=28.7179487179487, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24580925, Length=178, Percent_Identity=26.9662921348315, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI116007232, Length=189, Percent_Identity=32.2751322751323, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648693, Length=177, Percent_Identity=31.638418079096, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355889, Length=177, Percent_Identity=31.638418079096, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26172; Mature: 26041

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEERTAIVTGAGTGIGKSVATALLKAGWNTVFCGRRKAVLDAAIVEAGRTEAKALAVAC
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCHHEEEEEE
DISKAGEVDDLFETVAEAFGRVDLLFNNAGMGYKSTPIDEIPVEVWNDIVGVNLTGSFLC
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHCEECCCCCHHHHH
ARAAFGAMRKQRPMGGRIINNGSVSAYAPRPGSVPYTATKHAITGLTKTLALDGRPYDIA
HHHHHHHHHHCCCCCCEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHEEECCCCCEEE
CGQIDIGNALTDMAQPMTVGVPQANGSIAAEAVMDVQHVADAVVHMASLPLEANVLFMTV
ECEEECCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEH
MATKMPFVGRG
HHHHCCCCCCC
>Mature Secondary Structure 
TEERTAIVTGAGTGIGKSVATALLKAGWNTVFCGRRKAVLDAAIVEAGRTEAKALAVAC
CCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCHHEEEEEE
DISKAGEVDDLFETVAEAFGRVDLLFNNAGMGYKSTPIDEIPVEVWNDIVGVNLTGSFLC
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHCEECCCCCHHHHH
ARAAFGAMRKQRPMGGRIINNGSVSAYAPRPGSVPYTATKHAITGLTKTLALDGRPYDIA
HHHHHHHHHHCCCCCCEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHEEECCCCCEEE
CGQIDIGNALTDMAQPMTVGVPQANGSIAAEAVMDVQHVADAVVHMASLPLEANVLFMTV
ECEEECCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEH
MATKMPFVGRG
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]