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The map label for this gene is acoC [H]

Identifier: 13472482

GI number: 13472482

Start: 2244306

End: 2245109

Strand: Direct

Name: acoC [H]

Synonym: mlr2794

Alternate gene names: 13472482

Gene position: 2244306-2245109 (Clockwise)

Preceding gene: 13472481

Following gene: 13472483

Centisome position: 31.9

GC content: 65.17

Gene sequence:

>804_bases
ATGATCTCATCGCTCCATGCTTCCGAACAGGGTGCCGGTTCGAAGACCATCGTCTTGCTGCACGGCTTTGGCGGTTGCTC
CGACGTGTGGCGCGACGTGATCGCCCCGCTCTCCCCTTCCGCGCGCACCCTTGCCTACGACCTGCCGGGGCATGGCCTGT
CGCTGGACTTTCCCGATGCCGGGCCTGCTAAGGTCGCGGCAAGAGCCGTTCTTGCCGACCTTGCGGCCCGCAGGGTCAAA
CGCATCCATCTCGTTGGCCATTCGATGGGCGGAGCGGTGGCGACCTTGATGGCGCTGGCCGAGCCGGAGAAGGTTGCCTC
GCTGACGCTTCTGGCGCCCGGCGGCTTCGGCCCGGAGATCAACGGGCCGCTGTTGCGTCGCTATGCCGGCGCACAGAGCC
CGTCCGAGATCCTCGCCTGCCTTGCCGCCATGTCAGGTCCACGGGCGCGACCTTTTGATCACATCGCCGATACGCTCTGC
GAAATGCGCAAGCGGCCCGGACAATCAGAAAAGCTCGTTGAGATCGCCGCCGCCATGACCAGGGACGACCGGCAAGGCGT
CATCCCGCGCGAGCAGTTGGATAGGCTGGCCATGCCGGTGATGGTGGTGTGGGGCAGTGATGACGCGGTGCTGCCCTTCA
CCCAGGCTGATGACCTGCCGGTGCGCTTTCATGTGCATCATGTGTTGGAGGCCGGCCATATGCTGATCGAGGAAGCGCCC
GATCTGATCGCCAGCATCATCAGGCGCAATATGAACCGTCGCGCCAGGCCCCTTCGCCCCAAACTCGCCGCCGCGGCCAG
TTGA

Upstream 100 bases:

>100_bases
GCCCGCGCCCTCGCCTAATCGCGAAAATTTTACTGGTCATCCAGCTGGACAAAGCGCATCCAGCTAGATCAAGGCTTCCC
GTAATTCAGCACCCGCTTTC

Downstream 100 bases:

>100_bases
GTTGCTTAAGGCATGTCGCCCAAAAGTGACCTCGGTTTTGGGAGAATGACATGCAAAAAACAAAAGACCTGAAGCGCCTC
GCGTAACGCGACGCGCGTCA

Product: dihydrolipoamide S-acetyltransferase

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MISSLHASEQGAGSKTIVLLHGFGGCSDVWRDVIAPLSPSARTLAYDLPGHGLSLDFPDAGPAKVAARAVLADLAARRVK
RIHLVGHSMGGAVATLMALAEPEKVASLTLLAPGGFGPEINGPLLRRYAGAQSPSEILACLAAMSGPRARPFDHIADTLC
EMRKRPGQSEKLVEIAAAMTRDDRQGVIPREQLDRLAMPVMVVWGSDDAVLPFTQADDLPVRFHVHHVLEAGHMLIEEAP
DLIASIIRRNMNRRARPLRPKLAAAAS

Sequences:

>Translated_267_residues
MISSLHASEQGAGSKTIVLLHGFGGCSDVWRDVIAPLSPSARTLAYDLPGHGLSLDFPDAGPAKVAARAVLADLAARRVK
RIHLVGHSMGGAVATLMALAEPEKVASLTLLAPGGFGPEINGPLLRRYAGAQSPSEILACLAAMSGPRARPFDHIADTLC
EMRKRPGQSEKLVEIAAAMTRDDRQGVIPREQLDRLAMPVMVVWGSDDAVLPFTQADDLPVRFHVHHVLEAGHMLIEEAP
DLIASIIRRNMNRRARPLRPKLAAAAS
>Mature_267_residues
MISSLHASEQGAGSKTIVLLHGFGGCSDVWRDVIAPLSPSARTLAYDLPGHGLSLDFPDAGPAKVAARAVLADLAARRVK
RIHLVGHSMGGAVATLMALAEPEKVASLTLLAPGGFGPEINGPLLRRYAGAQSPSEILACLAAMSGPRARPFDHIADTLC
EMRKRPGQSEKLVEIAAAMTRDDRQGVIPREQLDRLAMPVMVVWGSDDAVLPFTQADDLPVRFHVHHVLEAGHMLIEEAP
DLIASIIRRNMNRRARPLRPKLAAAAS

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=280, Percent_Identity=25.3571428571429, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 28519; Mature: 28519

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSLHASEQGAGSKTIVLLHGFGGCSDVWRDVIAPLSPSARTLAYDLPGHGLSLDFPDA
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCEECCCCC
GPAKVAARAVLADLAARRVKRIHLVGHSMGGAVATLMALAEPEKVASLTLLAPGGFGPEI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHEEEEECCCCCCCCC
NGPLLRRYAGAQSPSEILACLAAMSGPRARPFDHIADTLCEMRKRPGQSEKLVEIAAAMT
CCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RDDRQGVIPREQLDRLAMPVMVVWGSDDAVLPFTQADDLPVRFHVHHVLEAGHMLIEEAP
CCCCCCCCCHHHHHHHCCCEEEEECCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHH
DLIASIIRRNMNRRARPLRPKLAAAAS
HHHHHHHHHHHHCCCCCCCCHHHHCCC
>Mature Secondary Structure
MISSLHASEQGAGSKTIVLLHGFGGCSDVWRDVIAPLSPSARTLAYDLPGHGLSLDFPDA
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCEECCCCC
GPAKVAARAVLADLAARRVKRIHLVGHSMGGAVATLMALAEPEKVASLTLLAPGGFGPEI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHEEEEECCCCCCCCC
NGPLLRRYAGAQSPSEILACLAAMSGPRARPFDHIADTLCEMRKRPGQSEKLVEIAAAMT
CCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RDDRQGVIPREQLDRLAMPVMVVWGSDDAVLPFTQADDLPVRFHVHHVLEAGHMLIEEAP
CCCCCCCCCHHHHHHHCCCEEEEECCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHH
DLIASIIRRNMNRRARPLRPKLAAAAS
HHHHHHHHHHHHCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]