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The map label for this gene is 13472421

Identifier: 13472421

GI number: 13472421

Start: 2178557

End: 2179441

Strand: Direct

Name: 13472421

Synonym: mlr2710

Alternate gene names: NA

Gene position: 2178557-2179441 (Clockwise)

Preceding gene: 13472420

Following gene: 13472422

Centisome position: 30.96

GC content: 63.73

Gene sequence:

>885_bases
ATGCAAGTCTCGACCGTCGAAATCGAAGGGCTGAGCATTGCCATCCGCGAGGCGGGTCCGGCCGAAGCGCCGGCATTCCT
CCTGCTGCATGGATGGCCGCAAAGCTCCTACGCGTTCGAACGGGTGATCGGCCGGCTGGCAGCCGACTACCGCGTCGTCG
CCCCCGACCTGCCCTGCATCGGCGCCTCGCAAGGCATGCCTCGGGCCGGTGACAAGCGGACCCTGGCAAGGCTGATGAGA
GGCGTCGCCGAAGCTTGCGAGCTGCGGCACCTCGTGGTCGCCGGCCATGATGTCGGCGGCCAGATCGTATTTGCCCTGTT
GCGCGAACATCCGGAGATTCTGTCCGGCGCGGTGATCATGGATGTCGTCATTCCAGGTGTAGCGCCGTGGGAGAACATCA
TTCGCAATCCGCAGATCTGGCACTTTGCATTCCATGCCGTTCCGGCCTTGCCGGAAACGCTGGTGAGCGGCCATCAGAGC
GCCTATTTCGACTTCTTCTTCAATGTGCTTTCGAAGGACCAAGCCTCGATCCCTGACGATGCCAGGGAAATCTACGCAAA
GGCCTATTCCCGGCCCGAAAGCCTCCAGGCCGGTTTCGACTGGTATCGCGCCTTCCCCGAGGATGCCAAGGCCAATGCCA
AGTGGGCCGGCAAGCCGATCGCGGTTCCGGTGCTGTATCTGAGGGGTGCGGCCGAGCCCGGCGAGATCGGCGACTATGTC
GATGGCCTGCGGGCGGCCGGGCTTTCAAATGTCGTGGGCGACATCATAGCCGACAGCGGACACTTCGTCGCCGACGAGAA
TCCCGAAGCGCTCGCCATCCGCCTGGCGCGATTCCATAGGGAAATCAGTGCGGCAAGCGCCGAGCCTACCGGGCGCCGAG
CCTGA

Upstream 100 bases:

>100_bases
GCACGTTCATCACAAAGTGGCTCGAGTGACGGTTCAAGGCCCTGTCGATTTCCCGATTGCCGCCTAGATCTATGGCATAG
GCAGTCGGCAGGATCAGGAC

Downstream 100 bases:

>100_bases
CCAGCACAGCCCTGGGGATGTCGTATTCGCGGATGACGCCATCGTGCTTGCGCAAGCCGCACAGCTCGCGCTGGATGAAA
TAGCCGTGCACCGCCTCGGC

Product: hydrolase

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQVSTVEIEGLSIAIREAGPAEAPAFLLLHGWPQSSYAFERVIGRLAADYRVVAPDLPCIGASQGMPRAGDKRTLARLMR
GVAEACELRHLVVAGHDVGGQIVFALLREHPEILSGAVIMDVVIPGVAPWENIIRNPQIWHFAFHAVPALPETLVSGHQS
AYFDFFFNVLSKDQASIPDDAREIYAKAYSRPESLQAGFDWYRAFPEDAKANAKWAGKPIAVPVLYLRGAAEPGEIGDYV
DGLRAAGLSNVVGDIIADSGHFVADENPEALAIRLARFHREISAASAEPTGRRA

Sequences:

>Translated_294_residues
MQVSTVEIEGLSIAIREAGPAEAPAFLLLHGWPQSSYAFERVIGRLAADYRVVAPDLPCIGASQGMPRAGDKRTLARLMR
GVAEACELRHLVVAGHDVGGQIVFALLREHPEILSGAVIMDVVIPGVAPWENIIRNPQIWHFAFHAVPALPETLVSGHQS
AYFDFFFNVLSKDQASIPDDAREIYAKAYSRPESLQAGFDWYRAFPEDAKANAKWAGKPIAVPVLYLRGAAEPGEIGDYV
DGLRAAGLSNVVGDIIADSGHFVADENPEALAIRLARFHREISAASAEPTGRRA
>Mature_294_residues
MQVSTVEIEGLSIAIREAGPAEAPAFLLLHGWPQSSYAFERVIGRLAADYRVVAPDLPCIGASQGMPRAGDKRTLARLMR
GVAEACELRHLVVAGHDVGGQIVFALLREHPEILSGAVIMDVVIPGVAPWENIIRNPQIWHFAFHAVPALPETLVSGHQS
AYFDFFFNVLSKDQASIPDDAREIYAKAYSRPESLQAGFDWYRAFPEDAKANAKWAGKPIAVPVLYLRGAAEPGEIGDYV
DGLRAAGLSNVVGDIIADSGHFVADENPEALAIRLARFHREISAASAEPTGRRA

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 31841; Mature: 31841

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSTVEIEGLSIAIREAGPAEAPAFLLLHGWPQSSYAFERVIGRLAADYRVVAPDLPCI
CCCEEEEECCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCC
GASQGMPRAGDKRTLARLMRGVAEACELRHLVVAGHDVGGQIVFALLREHPEILSGAVIM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCHHHHHHHHHH
DVVIPGVAPWENIIRNPQIWHFAFHAVPALPETLVSGHQSAYFDFFFNVLSKDQASIPDD
HHHHCCCCCHHHHHCCCCEEEHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCHH
AREIYAKAYSRPESLQAGFDWYRAFPEDAKANAKWAGKPIAVPVLYLRGAAEPGEIGDYV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHEEECCCCCCCHHHHH
DGLRAAGLSNVVGDIIADSGHFVADENPEALAIRLARFHREISAASAEPTGRRA
HHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQVSTVEIEGLSIAIREAGPAEAPAFLLLHGWPQSSYAFERVIGRLAADYRVVAPDLPCI
CCCEEEEECCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCC
GASQGMPRAGDKRTLARLMRGVAEACELRHLVVAGHDVGGQIVFALLREHPEILSGAVIM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCHHHHHHHHHH
DVVIPGVAPWENIIRNPQIWHFAFHAVPALPETLVSGHQSAYFDFFFNVLSKDQASIPDD
HHHHCCCCCHHHHHCCCCEEEHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCHH
AREIYAKAYSRPESLQAGFDWYRAFPEDAKANAKWAGKPIAVPVLYLRGAAEPGEIGDYV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHEEECCCCCCCHHHHH
DGLRAAGLSNVVGDIIADSGHFVADENPEALAIRLARFHREISAASAEPTGRRA
HHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]