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The map label for this gene is fbcH [H]

Identifier: 13472417

GI number: 13472417

Start: 2175063

End: 2175920

Strand: Reverse

Name: fbcH [H]

Synonym: mll2705

Alternate gene names: 13472417

Gene position: 2175920-2175063 (Counterclockwise)

Preceding gene: 13472418

Following gene: 13472416

Centisome position: 30.93

GC content: 64.45

Gene sequence:

>858_bases
ATGAAAAAGATTCTCACCTCGCTGGCGCTGGTTGGCCTTGTGGCCGCCGGCACCGCAGCGTTCGCGGCCGAAGAGGCGCA
CAACGCGGCGGCACCCACGCATTTCCCGATCAACGAGCCGAAGGAAATGAGCTGGAGCTTCACCGGCCCGTTCGGCACCT
ATGACAAGGCGCAGCTGCAGCGCGGCCTGAAGGTCTACAAGGAAGTCTGCTCGGCCTGCCATTCGATGAACCTGGTGGCG
TTCCGCACGCTGTCGGACCTCGGCTACAACGACGCCCAGATCAAGACGCTTGCCGCCGAATACACCGTCCATGACGGCCC
CAACGACGCCGGCGACATGTTCGACCGCCCCGGCAAGCCATCCGACCATTTCCCGGCGCCGTTCGCCAATGAGCAAGCCG
CCGCTGCCTCGAACGGCGGCGCGGCCCCGCCGGACATGTCGCTGCTGGCCAAGGCACGCGGCGTCGAGCGCGGCTTTCCG
CAGTTCGTCTTCGATATCTTCACCCAGTATGACGCGGGCGGCCCCGACTACATCCATTCGCTGCTGACCGGCTACGATCA
GACGCCGCCGGCCGGGATGGTCATTCCCGAGGGCACGCACTACAACCCATACTTCATGTCCGGCGTGTCGCTGAAGATGC
CCAAGCCGCTCTCCGACGGCCAGGTGACTTATGATGACGGTTCGCCGCAGACCGTCGACCAGTATGCCCGCGACGTATCA
GCCTTCCTGACCTGGGCGGCCGAGCCGCACATGGAAGCTCGCAAGAAGATGGGCTTCCGCGTGCTGGTGTTCCTGCTGCT
CTTCGGTGCGCTGGTCTATCTGACCAAGCGCAAGGTGTGGGAAGGCGTCGCGCACTAA

Upstream 100 bases:

>100_bases
GGTGCTCGAAAAGAACAAGGGCGGCAGCGGGCATCCGGCGGGCGCCACGGCCGCGCCAGAGACCAAGGGCTGAGCGGTAG
AGAATCTAAGGGGATTTGGC

Downstream 100 bases:

>100_bases
AGTATGCCGATATTCAGGTGATGCCGGCCTGCAAATGCCGGCATCCTGCGCTTCCGGTGCTCACGTACTTCAAGTACGCT
CCGCTCCGGTCCTCGGAAGC

Product: cytochrome c1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKKILTSLALVGLVAAGTAAFAAEEAHNAAAPTHFPINEPKEMSWSFTGPFGTYDKAQLQRGLKVYKEVCSACHSMNLVA
FRTLSDLGYNDAQIKTLAAEYTVHDGPNDAGDMFDRPGKPSDHFPAPFANEQAAAASNGGAAPPDMSLLAKARGVERGFP
QFVFDIFTQYDAGGPDYIHSLLTGYDQTPPAGMVIPEGTHYNPYFMSGVSLKMPKPLSDGQVTYDDGSPQTVDQYARDVS
AFLTWAAEPHMEARKKMGFRVLVFLLLFGALVYLTKRKVWEGVAH

Sequences:

>Translated_285_residues
MKKILTSLALVGLVAAGTAAFAAEEAHNAAAPTHFPINEPKEMSWSFTGPFGTYDKAQLQRGLKVYKEVCSACHSMNLVA
FRTLSDLGYNDAQIKTLAAEYTVHDGPNDAGDMFDRPGKPSDHFPAPFANEQAAAASNGGAAPPDMSLLAKARGVERGFP
QFVFDIFTQYDAGGPDYIHSLLTGYDQTPPAGMVIPEGTHYNPYFMSGVSLKMPKPLSDGQVTYDDGSPQTVDQYARDVS
AFLTWAAEPHMEARKKMGFRVLVFLLLFGALVYLTKRKVWEGVAH
>Mature_285_residues
MKKILTSLALVGLVAAGTAAFAAEEAHNAAAPTHFPINEPKEMSWSFTGPFGTYDKAQLQRGLKVYKEVCSACHSMNLVA
FRTLSDLGYNDAQIKTLAAEYTVHDGPNDAGDMFDRPGKPSDHFPAPFANEQAAAASNGGAAPPDMSLLAKARGVERGFP
QFVFDIFTQYDAGGPDYIHSLLTGYDQTPPAGMVIPEGTHYNPYFMSGVSLKMPKPLSDGQVTYDDGSPQTVDQYARDVS
AFLTWAAEPHMEARKKMGFRVLVFLLLFGALVYLTKRKVWEGVAH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=254, Percent_Identity=41.7322834645669, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17506225, Length=280, Percent_Identity=37.8571428571429, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324639, Length=289, Percent_Identity=40.4844290657439, Blast_Score=219, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24658292, Length=283, Percent_Identity=38.86925795053, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI21358225, Length=281, Percent_Identity=37.3665480427046, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 30961; Mature: 30961

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILTSLALVGLVAAGTAAFAAEEAHNAAAPTHFPINEPKEMSWSFTGPFGTYDKAQLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCEEECCCCCCCCHHHHH
RGLKVYKEVCSACHSMNLVAFRTLSDLGYNDAQIKTLAAEYTVHDGPNDAGDMFDRPGKP
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCHHHHHCCCCCC
SDHFPAPFANEQAAAASNGGAAPPDMSLLAKARGVERGFPQFVFDIFTQYDAGGPDYIHS
CCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHH
LLTGYDQTPPAGMVIPEGTHYNPYFMSGVSLKMPKPLSDGQVTYDDGSPQTVDQYARDVS
HHHCCCCCCCCCEEECCCCCCCCCEECCCCEECCCCCCCCEEEECCCCCHHHHHHHHHHH
AFLTWAAEPHMEARKKMGFRVLVFLLLFGALVYLTKRKVWEGVAH
HHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKILTSLALVGLVAAGTAAFAAEEAHNAAAPTHFPINEPKEMSWSFTGPFGTYDKAQLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCEEECCCCCCCCHHHHH
RGLKVYKEVCSACHSMNLVAFRTLSDLGYNDAQIKTLAAEYTVHDGPNDAGDMFDRPGKP
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCHHHHHCCCCCC
SDHFPAPFANEQAAAASNGGAAPPDMSLLAKARGVERGFPQFVFDIFTQYDAGGPDYIHS
CCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHH
LLTGYDQTPPAGMVIPEGTHYNPYFMSGVSLKMPKPLSDGQVTYDDGSPQTVDQYARDVS
HHHCCCCCCCCCEEECCCCCCCCCEECCCCEECCCCCCCCEEEECCCCCHHHHHHHHHHH
AFLTWAAEPHMEARKKMGFRVLVFLLLFGALVYLTKRKVWEGVAH
HHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]