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The map label for this gene is lldD [H]

Identifier: 13472415

GI number: 13472415

Start: 2172776

End: 2173921

Strand: Reverse

Name: lldD [H]

Synonym: mll2703

Alternate gene names: 13472415

Gene position: 2173921-2172776 (Counterclockwise)

Preceding gene: 13472416

Following gene: 13472414

Centisome position: 30.9

GC content: 63.0

Gene sequence:

>1146_bases
ATGCGACTCAACGACTGTCATAACTTCTCAGATTTCCGCCGCATGGCGCAGCGAAGGCTGCCGGGGCCGATCTTCGACTA
CATCGATGGCGCGGCCGACGACGAGGTCACCTATCGCCGCAACACCGAAAGTTTCGAGACCTGCGACCTCGTCCCCAACG
TGCTGCGCGGGGTGAATGAGATCGACATGTCGGTGACGGTGATGGGGCAGAAGCTGGCGATGCCGTTCTACTGCTCGCCG
ACCGCCCTGCAGCGGCTTTTCCATCACCAGGGCGAGCGCGCAGTGGCCAAGGCCGCCGCCAAATACGGCACCATGTTCGG
TGTCTCCTCGCTTGGCACCGTCAGCCTCGAGGAGGCTCGAAGCATCAGCAGCAGTCCGCAGGTCTACCAGTTCTATTTCC
ACCGGGATCGCGGCCTCAACCGGGCGATGATGCAGCGGGCGAAGCAAGTTGGCGTCGAGGTGATGATGCTGACCGTCGAC
AGCATAACGGGCGGCAATCGCGAGCGCGACAAGCGCACCGGCTTTGCCATTCCCTTCAAGCTCAACCTCGCGGGGATGGC
GCAGTTCGCGCTCAAGCCGGCCTGGGCGATCAATTATTTCACGCATGAAGGGTTCAAGCTGCCGCAGCTCGACGAGCATG
TCGACATGGGCGGCGGCACGATGTCGATCAGCCGCTATTTCACCGAAATGCTCGATCCGTCGATGACCTGGGACGATGTC
GCCGAGATGGTCAGGCAGTGGTCGGGGCCGTTCTGCCTCAAGGGCATCATGTCGGTCGAGGACGCCAAACGCGCCGCCGA
GATCGGCTGCAGCGGCATTGTGCTTTCCAATCATGGCGGCCGGCAGCTGGACGGGTCGCGGGCGGCATTCGACCAGCTGG
CCGAGATCGTCGAGGCCGTCGGCGACCGGATCGATGTCATCATGGATGGCGGCGTGCAGCGCGGCACACATGTGCTGAAG
GCCCTCTCGCTCGGCGCCAAGGCGGTCGGCATCGGCCGTTACTATCTGTTTCCGCTGGCGGCGGCCGGCCAGCCGGGTGT
CGAAAGGGCGCTTGAACAGATGCGGGTCGAGATCGAGCGCGGCATGAAGCTGATGGGCTGCAGTTCGATCGGACAATTGT
CGCGCCAGAATCTCCGATTTAGGTAA

Upstream 100 bases:

>100_bases
GCAGTTCCGCAATTAGTCCGTTGGCATGGCGCCATCGGATTGATATTCGACGCATCGAGGGGCGGCAAAGGCTGACCCGC
CACGGCCTTGGAAATCGATG

Downstream 100 bases:

>100_bases
TCTTCGCGGAGGGTGCCATGCCGGACAGCCAAAGCAGCAGTGATCGGGACGCCATCAGGGCGATCATCGTCCGCCAGTTC
GCAAGCCTGAGCTGGAGCGA

Product: glycolate oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRLNDCHNFSDFRRMAQRRLPGPIFDYIDGAADDEVTYRRNTESFETCDLVPNVLRGVNEIDMSVTVMGQKLAMPFYCSP
TALQRLFHHQGERAVAKAAAKYGTMFGVSSLGTVSLEEARSISSSPQVYQFYFHRDRGLNRAMMQRAKQVGVEVMMLTVD
SITGGNRERDKRTGFAIPFKLNLAGMAQFALKPAWAINYFTHEGFKLPQLDEHVDMGGGTMSISRYFTEMLDPSMTWDDV
AEMVRQWSGPFCLKGIMSVEDAKRAAEIGCSGIVLSNHGGRQLDGSRAAFDQLAEIVEAVGDRIDVIMDGGVQRGTHVLK
ALSLGAKAVGIGRYYLFPLAAAGQPGVERALEQMRVEIERGMKLMGCSSIGQLSRQNLRFR

Sequences:

>Translated_381_residues
MRLNDCHNFSDFRRMAQRRLPGPIFDYIDGAADDEVTYRRNTESFETCDLVPNVLRGVNEIDMSVTVMGQKLAMPFYCSP
TALQRLFHHQGERAVAKAAAKYGTMFGVSSLGTVSLEEARSISSSPQVYQFYFHRDRGLNRAMMQRAKQVGVEVMMLTVD
SITGGNRERDKRTGFAIPFKLNLAGMAQFALKPAWAINYFTHEGFKLPQLDEHVDMGGGTMSISRYFTEMLDPSMTWDDV
AEMVRQWSGPFCLKGIMSVEDAKRAAEIGCSGIVLSNHGGRQLDGSRAAFDQLAEIVEAVGDRIDVIMDGGVQRGTHVLK
ALSLGAKAVGIGRYYLFPLAAAGQPGVERALEQMRVEIERGMKLMGCSSIGQLSRQNLRFR
>Mature_381_residues
MRLNDCHNFSDFRRMAQRRLPGPIFDYIDGAADDEVTYRRNTESFETCDLVPNVLRGVNEIDMSVTVMGQKLAMPFYCSP
TALQRLFHHQGERAVAKAAAKYGTMFGVSSLGTVSLEEARSISSSPQVYQFYFHRDRGLNRAMMQRAKQVGVEVMMLTVD
SITGGNRERDKRTGFAIPFKLNLAGMAQFALKPAWAINYFTHEGFKLPQLDEHVDMGGGTMSISRYFTEMLDPSMTWDDV
AEMVRQWSGPFCLKGIMSVEDAKRAAEIGCSGIVLSNHGGRQLDGSRAAFDQLAEIVEAVGDRIDVIMDGGVQRGTHVLK
ALSLGAKAVGIGRYYLFPLAAAGQPGVERALEQMRVEIERGMKLMGCSSIGQLSRQNLRFR

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=372, Percent_Identity=36.0215053763441, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI54234014, Length=375, Percent_Identity=32.8, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI7705393, Length=375, Percent_Identity=32.8, Blast_Score=207, Evalue=1e-53,
Organism=Escherichia coli, GI1790033, Length=373, Percent_Identity=34.5844504021448, Blast_Score=228, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI193208036, Length=371, Percent_Identity=32.6145552560647, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI32566217, Length=287, Percent_Identity=29.9651567944251, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323587, Length=384, Percent_Identity=35.9375, Blast_Score=229, Evalue=5e-61,
Organism=Drosophila melanogaster, GI78707188, Length=365, Percent_Identity=34.5205479452055, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI281363140, Length=365, Percent_Identity=34.5205479452055, Blast_Score=225, Evalue=3e-59,
Organism=Drosophila melanogaster, GI78707190, Length=365, Percent_Identity=34.5205479452055, Blast_Score=225, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42337; Mature: 42337

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNDCHNFSDFRRMAQRRLPGPIFDYIDGAADDEVTYRRNTESFETCDLVPNVLRGVNE
CCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCCHH
IDMSVTVMGQKLAMPFYCSPTALQRLFHHQGERAVAKAAAKYGTMFGVSSLGTVSLEEAR
HCCEEEEECHHHCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
SISSSPQVYQFYFHRDRGLNRAMMQRAKQVGVEVMMLTVDSITGGNRERDKRTGFAIPFK
CCCCCCCEEEEEEHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHCCEEEEEE
LNLAGMAQFALKPAWAINYFTHEGFKLPQLDEHVDMGGGTMSISRYFTEMLDPSMTWDDV
ECHHHHHHHHHCCHHEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHH
AEMVRQWSGPFCLKGIMSVEDAKRAAEIGCSGIVLSNHGGRQLDGSRAAFDQLAEIVEAV
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
GDRIDVIMDGGVQRGTHVLKALSLGAKAVGIGRYYLFPLAAAGQPGVERALEQMRVEIER
CCCEEEEECCCHHHHHHHHHHHHCCCHHEECCHHEEEEECCCCCHHHHHHHHHHHHHHHH
GMKLMGCSSIGQLSRQNLRFR
CCEEECCHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLNDCHNFSDFRRMAQRRLPGPIFDYIDGAADDEVTYRRNTESFETCDLVPNVLRGVNE
CCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCCHH
IDMSVTVMGQKLAMPFYCSPTALQRLFHHQGERAVAKAAAKYGTMFGVSSLGTVSLEEAR
HCCEEEEECHHHCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
SISSSPQVYQFYFHRDRGLNRAMMQRAKQVGVEVMMLTVDSITGGNRERDKRTGFAIPFK
CCCCCCCEEEEEEHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHCCEEEEEE
LNLAGMAQFALKPAWAINYFTHEGFKLPQLDEHVDMGGGTMSISRYFTEMLDPSMTWDDV
ECHHHHHHHHHCCHHEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHH
AEMVRQWSGPFCLKGIMSVEDAKRAAEIGCSGIVLSNHGGRQLDGSRAAFDQLAEIVEAV
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
GDRIDVIMDGGVQRGTHVLKALSLGAKAVGIGRYYLFPLAAAGQPGVERALEQMRVEIER
CCCEEEEECCCHHHHHHHHHHHHCCCHHEECCHHEEEEECCCCCHHHHHHHHHHHHHHHH
GMKLMGCSSIGQLSRQNLRFR
CCEEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA