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The map label for this gene is tdcF [C]

Identifier: 13472279

GI number: 13472279

Start: 2046837

End: 2047229

Strand: Reverse

Name: tdcF [C]

Synonym: mll2520

Alternate gene names: 13472279

Gene position: 2047229-2046837 (Counterclockwise)

Preceding gene: 13472280

Following gene: 13472278

Centisome position: 29.1

GC content: 61.07

Gene sequence:

>393_bases
ATGAAGAAACAAGTCATCGAAGTGCCTGTCATGTCGGACAAGGTCCGCTCACTCGGCCTGCCCTGTTCGACGGCGGTGAA
GGCCAATGGCTTCGTCTTCATCTCGGCGACGCCGCCGGTGGACATGGTGACCGGCGAGATGGTGCGCGGCGACATCGAAA
CGCAGACCGAGGCATCGCTGAAGGCGCTCAAACACTGCCTGGAGGCGGCCGGCACCTCGCTGGACAATGTGGTGATGGTG
CGCATCTACGCCGTCAATTCCGGCTTCTACAACGCCATCAACCGGGTCTACGCGCGGTTTTTTTCGACCAACCCGCCGGC
GCGGAGTTTCGTGCCGGTGGCGTCATGGCCGATGGAATTTGATATCGAGATCGAGTGTGTCGCGGTGGCGTGA

Upstream 100 bases:

>100_bases
TCGCGAACCGGCTGCTCACCCCACAAGGGGAGAAGGAAGAACAGCGCTGGCGTTCGCCGGCCGGCCGGATAAGCTCCCTG
CCAGCCAAGGGAGCATCACC

Downstream 100 bases:

>100_bases
GTCTACCTCCGCGAACCGGCATCCATGCTGGTTGTTTCCTGAAATTTTGGTCTGCAAAAAACGCCGCTTCATGCTGACGC
GTGGTTTCCATTGAGCGGCG

Product: translation initiation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MKKQVIEVPVMSDKVRSLGLPCSTAVKANGFVFISATPPVDMVTGEMVRGDIETQTEASLKALKHCLEAAGTSLDNVVMV
RIYAVNSGFYNAINRVYARFFSTNPPARSFVPVASWPMEFDIEIECVAVA

Sequences:

>Translated_130_residues
MKKQVIEVPVMSDKVRSLGLPCSTAVKANGFVFISATPPVDMVTGEMVRGDIETQTEASLKALKHCLEAAGTSLDNVVMV
RIYAVNSGFYNAINRVYARFFSTNPPARSFVPVASWPMEFDIEIECVAVA
>Mature_130_residues
MKKQVIEVPVMSDKVRSLGLPCSTAVKANGFVFISATPPVDMVTGEMVRGDIETQTEASLKALKHCLEAAGTSLDNVVMV
RIYAVNSGFYNAINRVYARFFSTNPPARSFVPVASWPMEFDIEIECVAVA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0251

COG function: function code J; Putative translation initiation inhibitor, yjgF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RutC family [H]

Homologues:

Organism=Homo sapiens, GI5032215, Length=109, Percent_Identity=33.0275229357798, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082213, Length=112, Percent_Identity=33.0357142857143, Blast_Score=59, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25148896, Length=110, Percent_Identity=38.1818181818182, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982068, Length=110, Percent_Identity=38.1818181818182, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982075, Length=110, Percent_Identity=38.1818181818182, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320899, Length=120, Percent_Identity=35.8333333333333, Blast_Score=77, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322138, Length=107, Percent_Identity=38.3177570093458, Blast_Score=76, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921376, Length=109, Percent_Identity=33.9449541284404, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013813
- InterPro:   IPR006175
- InterPro:   IPR006056
- InterPro:   IPR019897 [H]

Pfam domain/function: PF01042 Ribonuc_L-PSP [H]

EC number: NA

Molecular weight: Translated: 14162; Mature: 14162

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQVIEVPVMSDKVRSLGLPCSTAVKANGFVFISATPPVDMVTGEMVRGDIETQTEASL
CCCCEEECCCCCHHHHHCCCCCCCEEECCCEEEEECCCCCCHHCCHHHCCCCCCCHHHHH
KALKHCLEAAGTSLDNVVMVRIYAVNSGFYNAINRVYARFFSTNPPARSFVPVASWPMEF
HHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEE
DIEIECVAVA
CEEEEEEEEC
>Mature Secondary Structure
MKKQVIEVPVMSDKVRSLGLPCSTAVKANGFVFISATPPVDMVTGEMVRGDIETQTEASL
CCCCEEECCCCCHHHHHCCCCCCCEEECCCEEEEECCCCCCHHCCHHHCCCCCCCHHHHH
KALKHCLEAAGTSLDNVVMVRIYAVNSGFYNAINRVYARFFSTNPPARSFVPVASWPMEF
HHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEE
DIEIECVAVA
CEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]