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The map label for this gene is adc2

Identifier: 13472187

GI number: 13472187

Start: 1952062

End: 1952847

Strand: Direct

Name: adc2

Synonym: mlr2399

Alternate gene names: 13472187

Gene position: 1952062-1952847 (Clockwise)

Preceding gene: 13472186

Following gene: 13472188

Centisome position: 27.74

GC content: 60.56

Gene sequence:

>786_bases
ATGCATCAAGACACCGTCCGGGCAACGGCCTTCGCCATGCCCCTGACCAGCCCGGCCTATCCGGTCGGTCCGTACCGTTT
CCGCAATCGCGAATACCTGATCATCACGTATCGGACAGATCCAAAGAAACTGCGCAGTCTCGTGCCGGAGCCGCTCGAAC
TATCCGAACCCCTCGTGAAGTTCGAGTTCATTCGCATGCCGGACTCGACGGGCTTCGGCAACTACACGGAGAGCGGACAG
GTCATCCCTGTCACGTTCCGCGGCCGCAAAGGCAGCTACACCCACTGCATGTTTCTTAACGACCATCCACCGATTGCCGG
AGGGCGCGAGCTTTGGGGTTTTCCCAAGAAGCTTGCCACTCCGACACTGCGCACCGAGACTGACACCTTGGTGGGTACTC
TTGATTACGGCCCGGTCCGTGTTGCCACGGCCACCATGGGCTACAAGCACGAAGCAGCCGACCTCTCGGCAGTGAGGAGT
TCCCTCGCGGAGCCGAACTTCCTCCTCAAGATCATTCCCCATGTGGACGGCACGCCGCGCATCTGCGAGCTCGTGGAATA
TCACCTGGAGGACGTCGATCTGAGAGGCGCCTGGGCCGGCCCGGCATCCCTGAACCTCTGGTCGCATGCGCTGGCCCCGG
TCGCCGAGCTGCCGGTACTAGAGGTGGTTTCGGCGATGCACATCGTCGCCGATCTCACACTCGCACTCGGTAAGGTCGTT
CATGACTATCTACCGAAATCCGAGCCTCGCGATCTGAAAGGAAGATCCCATGCGTTCGCAGAATGA

Upstream 100 bases:

>100_bases
GCGTGCAATGGTGCCTGACATGCTCCGTTCAATCGCAAGCCTATGCGGCTCCTCCTCAACGCGAGCCATCCACGTCAACA
ATTGAAGGAATTCTTCAGCC

Downstream 100 bases:

>100_bases
AGCTCTTACTCACAATTGGACAGAGGACGGCGGCGGTCGGCTCATGGATAAGGTCGTGGTAGTCACCGGAGCCGCGAGTG
GTATTGGCAAAGAGATAGCC

Product: acetoacetate decarboxylase

Products: NA

Alternate protein names: AAD 2; ADC 2

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MHQDTVRATAFAMPLTSPAYPVGPYRFRNREYLIITYRTDPKKLRSLVPEPLELSEPLVKFEFIRMPDSTGFGNYTESGQ
VIPVTFRGRKGSYTHCMFLNDHPPIAGGRELWGFPKKLATPTLRTETDTLVGTLDYGPVRVATATMGYKHEAADLSAVRS
SLAEPNFLLKIIPHVDGTPRICELVEYHLEDVDLRGAWAGPASLNLWSHALAPVAELPVLEVVSAMHIVADLTLALGKVV
HDYLPKSEPRDLKGRSHAFAE

Sequences:

>Translated_261_residues
MHQDTVRATAFAMPLTSPAYPVGPYRFRNREYLIITYRTDPKKLRSLVPEPLELSEPLVKFEFIRMPDSTGFGNYTESGQ
VIPVTFRGRKGSYTHCMFLNDHPPIAGGRELWGFPKKLATPTLRTETDTLVGTLDYGPVRVATATMGYKHEAADLSAVRS
SLAEPNFLLKIIPHVDGTPRICELVEYHLEDVDLRGAWAGPASLNLWSHALAPVAELPVLEVVSAMHIVADLTLALGKVV
HDYLPKSEPRDLKGRSHAFAE
>Mature_261_residues
MHQDTVRATAFAMPLTSPAYPVGPYRFRNREYLIITYRTDPKKLRSLVPEPLELSEPLVKFEFIRMPDSTGFGNYTESGQ
VIPVTFRGRKGSYTHCMFLNDHPPIAGGRELWGFPKKLATPTLRTETDTLVGTLDYGPVRVATATMGYKHEAADLSAVRS
SLAEPNFLLKIIPHVDGTPRICELVEYHLEDVDLRGAWAGPASLNLWSHALAPVAELPVLEVVSAMHIVADLTLALGKVV
HDYLPKSEPRDLKGRSHAFAE

Specific function: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide

COG id: COG4689

COG function: function code Q; Acetoacetate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADC2_RHILO (Q98IH6)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103754.1
- ProteinModelPortal:   Q98IH6
- SMR:   Q98IH6
- GeneID:   1226415
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr2399
- NMPDR:   fig|266835.1.peg.1858
- HOGENOM:   HBG294597
- OMA:   MGYKHRP
- ProtClustDB:   PRK02265
- BRENDA:   4.1.1.4
- HAMAP:   MF_00597
- InterPro:   IPR010451

Pfam domain/function: PF06314 ADC

EC number: =4.1.1.4

Molecular weight: Translated: 29003; Mature: 29003

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQDTVRATAFAMPLTSPAYPVGPYRFRNREYLIITYRTDPKKLRSLVPEPLELSEPLVK
CCCCHHHHHEEECCCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHHCCCCHHHCCCCEE
FEFIRMPDSTGFGNYTESGQVIPVTFRGRKGSYTHCMFLNDHPPIAGGRELWGFPKKLAT
EEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHHHCCCCHHHCC
PTLRTETDTLVGTLDYGPVRVATATMGYKHEAADLSAVRSSLAEPNFLLKIIPHVDGTPR
CCCCCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHH
ICELVEYHLEDVDLRGAWAGPASLNLWSHALAPVAELPVLEVVSAMHIVADLTLALGKVV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HDYLPKSEPRDLKGRSHAFAE
HHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHQDTVRATAFAMPLTSPAYPVGPYRFRNREYLIITYRTDPKKLRSLVPEPLELSEPLVK
CCCCHHHHHEEECCCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHHCCCCHHHCCCCEE
FEFIRMPDSTGFGNYTESGQVIPVTFRGRKGSYTHCMFLNDHPPIAGGRELWGFPKKLAT
EEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHHHCCCCHHHCC
PTLRTETDTLVGTLDYGPVRVATATMGYKHEAADLSAVRSSLAEPNFLLKIIPHVDGTPR
CCCCCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHH
ICELVEYHLEDVDLRGAWAGPASLNLWSHALAPVAELPVLEVVSAMHIVADLTLALGKVV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HDYLPKSEPRDLKGRSHAFAE
HHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968