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The map label for this gene is dgoD [H]

Identifier: 13472125

GI number: 13472125

Start: 1871561

End: 1872919

Strand: Reverse

Name: dgoD [H]

Synonym: mll2322

Alternate gene names: 13472125

Gene position: 1872919-1871561 (Counterclockwise)

Preceding gene: 13472126

Following gene: 13472124

Centisome position: 26.62

GC content: 62.99

Gene sequence:

>1359_bases
ATGCCAAAGACGGATGGAGCCGGCGAGGCTCTCAATCGGGTCAACACGAATTCCAAACCATCCGACCTTCGCATCACCGA
CATGCGGGTTGCCGAAATCGTCGGCGCACCATTCACCTCGGCGCTGCTCAAGATCTATACCAATCAGGGGATCGTCGGGC
TCGGCGAGGTGCGTGACGGCGCCAGCGCCACCTACGCGCTGATGCTCAAAAGCCGGCTGCTTGGCGAGAACCCTTGCGAC
ATCGATCGCCTGTTTCGCCGCATCAAGCAGTTCGGCGGGCACGGCCGGCAGGGCGGCGGCGTGTCGGCGGTCGAGATCGC
CCTGTGGGATCTCGCCGGCAAGGCCTATGGCGTCCCCGTCTACCAGATGCTCGGCGGCAAGTTTCGCGATCAGGTGCGCG
TCTATTGCGATACCGATGCCGAGAAGCCGAGCGGCACCGAAACCGGAAAGCGCCTCAAGCAGCGCATGGACCGCGGGTTC
ACCTTCCTCAAGATGGACCTGGGCTTGATGCAGATCGCCCATGTCGCGGGCGCCGTATCCGCGCCCGCCGGCGCGCTCGA
CGGGTTTCATGCCAATCCACGCGGCCGTGGCGGCACGCTCGGGGAGCGCAAGGCCCGCAATCTAGCCTATGATGCGCAGA
ACGTGCAGCACCCATTCACCGGCCTGCATTTCACCGAAAAGGGGATCGATCTGCTCGAGCAGTATATCCACGAGGTTCGC
GAGGTGATCGGATACGAGATCCCGCTCGCCATCGACCATGTCGGCCACATCTCGCTGCAGGACGGCATACGCCTGTCGCG
CCGTATCGAGAAATACGTTCCGGCCTGGCTGGAGGACGTCATCCCCTGGCAATATACCGAGCAGTACCGGCAATTGCAGC
AAGCCACCACGGTGCCGATCTGCACCGGCGAGGACATCTACCTCAAGGAAGGCTTCGAGCCTCTGCTCAAGAGCGGCGGC
CTCTCGGTCATCCACCCGGATCTGCTCACCAGCGGGGGCATCCTCGAAACCAAGAAGATCGGCGACATGGCGCAGGATCA
CGGCGTCGCCATGGCCATTCATATGGCCGAAAGCCCGATCGCCGCGATGGCCGCGGCACATGTCGCCACCGCGACCGAGA
ACTTCATGGCGCTCGAATACCACTCCGCCGATGTCGACTGGTGGGACGATATCGTCACCGGCCTCCCCAAGCCGCTCGTC
AAGGACGGCTTCATTACCGTGCCCGACAGGCCGGGGCTGGGCATAGACGATGTGGTCGACGAGGTGATCAGCCAGCATCT
GCAGCCCGGTGTCACGGGGATATGGCAATCCACCGAGCATTGGGACAATGAATATAGCTGGGACCGGACCTGGAGTTAG

Upstream 100 bases:

>100_bases
CGCGACTACCTGCAAGCCCATGAGATCGAGCTGGGCTAGCAACGCTCAATGCCGGGCGGCGCCTTGGGCGACAAGCCCCC
GGCCAAAACGAGGACAAATC

Downstream 100 bases:

>100_bases
CCCAGCCCCCCTGCCATCATTCTCCCAGGCTCACAGGGCCAACGACCGACCATTCGTGTCGACCTCTCCCACGGGAGAGG
CGAAGAAAGAAACGGACGAA

Product: hypothetical protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MPKTDGAGEALNRVNTNSKPSDLRITDMRVAEIVGAPFTSALLKIYTNQGIVGLGEVRDGASATYALMLKSRLLGENPCD
IDRLFRRIKQFGGHGRQGGGVSAVEIALWDLAGKAYGVPVYQMLGGKFRDQVRVYCDTDAEKPSGTETGKRLKQRMDRGF
TFLKMDLGLMQIAHVAGAVSAPAGALDGFHANPRGRGGTLGERKARNLAYDAQNVQHPFTGLHFTEKGIDLLEQYIHEVR
EVIGYEIPLAIDHVGHISLQDGIRLSRRIEKYVPAWLEDVIPWQYTEQYRQLQQATTVPICTGEDIYLKEGFEPLLKSGG
LSVIHPDLLTSGGILETKKIGDMAQDHGVAMAIHMAESPIAAMAAAHVATATENFMALEYHSADVDWWDDIVTGLPKPLV
KDGFITVPDRPGLGIDDVVDEVISQHLQPGVTGIWQSTEHWDNEYSWDRTWS

Sequences:

>Translated_452_residues
MPKTDGAGEALNRVNTNSKPSDLRITDMRVAEIVGAPFTSALLKIYTNQGIVGLGEVRDGASATYALMLKSRLLGENPCD
IDRLFRRIKQFGGHGRQGGGVSAVEIALWDLAGKAYGVPVYQMLGGKFRDQVRVYCDTDAEKPSGTETGKRLKQRMDRGF
TFLKMDLGLMQIAHVAGAVSAPAGALDGFHANPRGRGGTLGERKARNLAYDAQNVQHPFTGLHFTEKGIDLLEQYIHEVR
EVIGYEIPLAIDHVGHISLQDGIRLSRRIEKYVPAWLEDVIPWQYTEQYRQLQQATTVPICTGEDIYLKEGFEPLLKSGG
LSVIHPDLLTSGGILETKKIGDMAQDHGVAMAIHMAESPIAAMAAAHVATATENFMALEYHSADVDWWDDIVTGLPKPLV
KDGFITVPDRPGLGIDDVVDEVISQHLQPGVTGIWQSTEHWDNEYSWDRTWS
>Mature_451_residues
PKTDGAGEALNRVNTNSKPSDLRITDMRVAEIVGAPFTSALLKIYTNQGIVGLGEVRDGASATYALMLKSRLLGENPCDI
DRLFRRIKQFGGHGRQGGGVSAVEIALWDLAGKAYGVPVYQMLGGKFRDQVRVYCDTDAEKPSGTETGKRLKQRMDRGFT
FLKMDLGLMQIAHVAGAVSAPAGALDGFHANPRGRGGTLGERKARNLAYDAQNVQHPFTGLHFTEKGIDLLEQYIHEVRE
VIGYEIPLAIDHVGHISLQDGIRLSRRIEKYVPAWLEDVIPWQYTEQYRQLQQATTVPICTGEDIYLKEGFEPLLKSGGL
SVIHPDLLTSGGILETKKIGDMAQDHGVAMAIHMAESPIAAMAAAHVATATENFMALEYHSADVDWWDDIVTGLPKPLVK
DGFITVPDRPGLGIDDVVDEVISQHLQPGVTGIWQSTEHWDNEYSWDRTWS

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=402, Percent_Identity=26.1194029850746, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787864, Length=387, Percent_Identity=28.4237726098191, Blast_Score=124, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 49727; Mature: 49596

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTDGAGEALNRVNTNSKPSDLRITDMRVAEIVGAPFTSALLKIYTNQGIVGLGEVRDG
CCCCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCC
ASATYALMLKSRLLGENPCDIDRLFRRIKQFGGHGRQGGGVSAVEIALWDLAGKAYGVPV
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
YQMLGGKFRDQVRVYCDTDAEKPSGTETGKRLKQRMDRGFTFLKMDLGLMQIAHVAGAVS
HHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHC
APAGALDGFHANPRGRGGTLGERKARNLAYDAQNVQHPFTGLHFTEKGIDLLEQYIHEVR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EVIGYEIPLAIDHVGHISLQDGIRLSRRIEKYVPAWLEDVIPWQYTEQYRQLQQATTVPI
HHHCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCE
CTGEDIYLKEGFEPLLKSGGLSVIHPDLLTSGGILETKKIGDMAQDHGVAMAIHMAESPI
ECCCCEEHHCCCHHHHHCCCCEEECHHHHCCCCCEEHHHHHHHHHHCCEEEEEEECCCCH
AAMAAAHVATATENFMALEYHSADVDWWDDIVTGLPKPLVKDGFITVPDRPGLGIDDVVD
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCHHHCCEEECCCCCCCCHHHHHH
EVISQHLQPGVTGIWQSTEHWDNEYSWDRTWS
HHHHHHHCCCCHHHCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PKTDGAGEALNRVNTNSKPSDLRITDMRVAEIVGAPFTSALLKIYTNQGIVGLGEVRDG
CCCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCC
ASATYALMLKSRLLGENPCDIDRLFRRIKQFGGHGRQGGGVSAVEIALWDLAGKAYGVPV
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
YQMLGGKFRDQVRVYCDTDAEKPSGTETGKRLKQRMDRGFTFLKMDLGLMQIAHVAGAVS
HHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHC
APAGALDGFHANPRGRGGTLGERKARNLAYDAQNVQHPFTGLHFTEKGIDLLEQYIHEVR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EVIGYEIPLAIDHVGHISLQDGIRLSRRIEKYVPAWLEDVIPWQYTEQYRQLQQATTVPI
HHHCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCE
CTGEDIYLKEGFEPLLKSGGLSVIHPDLLTSGGILETKKIGDMAQDHGVAMAIHMAESPI
ECCCCEEHHCCCHHHHHCCCCEEECHHHHCCCCCEEHHHHHHHHHHCCEEEEEEECCCCH
AAMAAAHVATATENFMALEYHSADVDWWDDIVTGLPKPLVKDGFITVPDRPGLGIDDVVD
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCHHHCCEEECCCCCCCCHHHHHH
EVISQHLQPGVTGIWQSTEHWDNEYSWDRTWS
HHHHHHHCCCCHHHCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA