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The map label for this gene is ybhD [H]

Identifier: 13472031

GI number: 13472031

Start: 1776788

End: 1777981

Strand: Direct

Name: ybhD [H]

Synonym: mlr2195

Alternate gene names: 13472031

Gene position: 1776788-1777981 (Clockwise)

Preceding gene: 13472028

Following gene: 13472032

Centisome position: 25.25

GC content: 68.68

Gene sequence:

>1194_bases
ATGCGCTTCGATCTCACCGATCTCCGGCTGTTCCTGCTGGTGGCCGAGCGCGGCAGCATCACCCACGGCGCCGAGCTTGC
CGGGCTGGCGCTGGCCTCGGCGAGCGCCCGCATCAAAGGCATGGAGGAGCGGCTCGGCGCGCCGCTGCTGGAACGCCGCC
GCCGCGGCGTGGTGCCGACGGCGGCCGGCCAGGCGCTGCTGCATCATGCGCGCGCCGTGCAGAACCAGATCGAGGCGATG
GCCGGCGACCTCCGCGCCTATGCCGGCGGCCTGCGCGCCCGTGTCCGGCTGATGGCCAACACCGCCGCCACGGCCGAGCT
TTTGCGTGACATCCTGCCGGCCTTCCTCGTCGCGCATCCCGGCATCGACATTGATTTGGACGAGCGCCCCAGCCACGAGA
TCGCCGAGGCGGTGGCGAGCGGTGCGGCCGATCTCGGCATCGCCGCGACCTGGGCCGGCCTCTCGCATCTCGAACAGAAA
CCGTTCTTCATCGACCGGCTGGTGGTGATCCTCGCGCGGAACTGGCCGGGGCTTGCCGGCCGGCATAGCGCCAGCCTCGC
CGACATGCTGGGCGAATCCTTTGTTGGCCTCAGCCTCGGCCACGCCCTGCAGGAGCACATCAACCGCCAGGCCGCACGCC
TGGGCCGCCATCTGCACATCCGCATCCGCGTGCCCGGCCTCGACAATGTCTGCCGGCTGGTCGCGCAAGGCGCCGGCATC
GCCATCGTGCCGGAGAGTGCGGCGCCGCTCGCCCCGCACATTGCGCAGCTTGCGGCTCAGCGACGACTGGGCCACGCGGC
AGCTCAATTTGTGCGCCCGCAGCTTCGACGAGTTGACACCGCAGGCAAAGCTGCTGGCCGCGGCCCTGGCCGGAGCCGAA
ACGGGTGGCCTGCCGGGCCGTTACCAGGGCAACGGACCCTCATCATAGAAATAGCCGCCGGTCGGACCGTTTTTGTCCAG
GGTCGCCAGGCGAACAATGATCTCGGCCGCCTGCCCCACGGTGCGGTAGCCGCTGTGTCCGTTGAAGTCCGTCGCGGTAT
AGCCGGGATCGGCCGAATTGACCTTAATACCCGCTGCGGCAAACTCCTTCGAGAAGGCAACGGTGGCGGCGTTGAGCGCC
GTCTTGGAGCTGTTGTAGCCAAGGATATTGATCGCATAGAACTCACTGGCCGGATCGGTCAACCCGCCGAGTGA

Upstream 100 bases:

>100_bases
GACGGACATCGGGCCCGCGCACAATGTGGAAGTTGCGCTGTCAGCCTTCGTCCAGGCCGAAGGCTGAAGCCAACGCCATG
CACCTCGCAGGGAGCAAGAA

Downstream 100 bases:

>100_bases
CCCCAGCCCGCTGGAAACCATCACCACATTGGCGCACGGGGCGGCCTTGAGCAGCGGCAGGAAGGCCTGCGTGGTGCGGA
TCGGGCCGAACACGTTGACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRFDLTDLRLFLLVAERGSITHGAELAGLALASASARIKGMEERLGAPLLERRRRGVVPTAAGQALLHHARAVQNQIEAM
AGDLRAYAGGLRARVRLMANTAATAELLRDILPAFLVAHPGIDIDLDERPSHEIAEAVASGAADLGIAATWAGLSHLEQK
PFFIDRLVVILARNWPGLAGRHSASLADMLGESFVGLSLGHALQEHINRQAARLGRHLHIRIRVPGLDNVCRLVAQGAGI
AIVPESAAPLAPHIAQLAAQRRLGHAAAQFVRPQLRRVDTAGKAAGRGPGRSRNGWPAGPLPGQRTLIIEIAAGRTVFVQ
GRQANNDLGRLPHGAVAAVSVEVRRGIAGIGRIDLNTRCGKLLREGNGGGVERRLGAVVAKDIDRIELTGRIGQPAE

Sequences:

>Translated_397_residues
MRFDLTDLRLFLLVAERGSITHGAELAGLALASASARIKGMEERLGAPLLERRRRGVVPTAAGQALLHHARAVQNQIEAM
AGDLRAYAGGLRARVRLMANTAATAELLRDILPAFLVAHPGIDIDLDERPSHEIAEAVASGAADLGIAATWAGLSHLEQK
PFFIDRLVVILARNWPGLAGRHSASLADMLGESFVGLSLGHALQEHINRQAARLGRHLHIRIRVPGLDNVCRLVAQGAGI
AIVPESAAPLAPHIAQLAAQRRLGHAAAQFVRPQLRRVDTAGKAAGRGPGRSRNGWPAGPLPGQRTLIIEIAAGRTVFVQ
GRQANNDLGRLPHGAVAAVSVEVRRGIAGIGRIDLNTRCGKLLREGNGGGVERRLGAVVAKDIDRIELTGRIGQPAE
>Mature_397_residues
MRFDLTDLRLFLLVAERGSITHGAELAGLALASASARIKGMEERLGAPLLERRRRGVVPTAAGQALLHHARAVQNQIEAM
AGDLRAYAGGLRARVRLMANTAATAELLRDILPAFLVAHPGIDIDLDERPSHEIAEAVASGAADLGIAATWAGLSHLEQK
PFFIDRLVVILARNWPGLAGRHSASLADMLGESFVGLSLGHALQEHINRQAARLGRHLHIRIRVPGLDNVCRLVAQGAGI
AIVPESAAPLAPHIAQLAAQRRLGHAAAQFVRPQLRRVDTAGKAAGRGPGRSRNGWPAGPLPGQRTLIIEIAAGRTVFVQ
GRQANNDLGRLPHGAVAAVSVEVRRGIAGIGRIDLNTRCGKLLREGNGGGVERRLGAVVAKDIDRIELTGRIGQPAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=253, Percent_Identity=26.4822134387352, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=24.6575342465753, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=241, Percent_Identity=25.3112033195021, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788748, Length=291, Percent_Identity=26.1168384879725, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786713, Length=111, Percent_Identity=38.7387387387387, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=196, Percent_Identity=30.6122448979592, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 42101; Mature: 42101

Theoretical pI: Translated: 11.72; Mature: 11.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDLTDLRLFLLVAERGSITHGAELAGLALASASARIKGMEERLGAPLLERRRRGVVPT
CCCCHHHHEEEHEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCCC
AAGQALLHHARAVQNQIEAMAGDLRAYAGGLRARVRLMANTAATAELLRDILPAFLVAHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIDIDLDERPSHEIAEAVASGAADLGIAATWAGLSHLEQKPFFIDRLVVILARNWPGLAG
CCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
RHSASLADMLGESFVGLSLGHALQEHINRQAARLGRHLHIRIRVPGLDNVCRLVAQGAGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCE
AIVPESAAPLAPHIAQLAAQRRLGHAAAQFVRPQLRRVDTAGKAAGRGPGRSRNGWPAGP
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LPGQRTLIIEIAAGRTVFVQGRQANNDLGRLPHGAVAAVSVEVRRGIAGIGRIDLNTRCG
CCCCEEEEEEEECCCEEEEECCCCCCCHHCCCCCCHHEEHHHHHHCCCCCCEECCCHHHH
KLLREGNGGGVERRLGAVVAKDIDRIELTGRIGQPAE
HHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure
MRFDLTDLRLFLLVAERGSITHGAELAGLALASASARIKGMEERLGAPLLERRRRGVVPT
CCCCHHHHEEEHEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCCC
AAGQALLHHARAVQNQIEAMAGDLRAYAGGLRARVRLMANTAATAELLRDILPAFLVAHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIDIDLDERPSHEIAEAVASGAADLGIAATWAGLSHLEQKPFFIDRLVVILARNWPGLAG
CCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
RHSASLADMLGESFVGLSLGHALQEHINRQAARLGRHLHIRIRVPGLDNVCRLVAQGAGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCE
AIVPESAAPLAPHIAQLAAQRRLGHAAAQFVRPQLRRVDTAGKAAGRGPGRSRNGWPAGP
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LPGQRTLIIEIAAGRTVFVQGRQANNDLGRLPHGAVAAVSVEVRRGIAGIGRIDLNTRCG
CCCCEEEEEEEECCCEEEEECCCCCCCHHCCCCCCHHEEHHHHHHCCCCCCEECCCHHHH
KLLREGNGGGVERRLGAVVAKDIDRIELTGRIGQPAE
HHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]