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The map label for this gene is blh [H]

Identifier: 13472001

GI number: 13472001

Start: 1752438

End: 1753733

Strand: Direct

Name: blh [H]

Synonym: mlr2158

Alternate gene names: 13472001

Gene position: 1752438-1753733 (Clockwise)

Preceding gene: 13471999

Following gene: 13472002

Centisome position: 24.91

GC content: 62.19

Gene sequence:

>1296_bases
ATGACCATGATCCGTGTAAATGACGTGCTGAGCGTCGGTCCTCAGCCCTCGATCTCCGAAATCCGGTCGCTTGCCGGCCA
TGGGTTTGCGGGAATGATCAACGCTCGACCTGACGGCGAAGAGGCTTCCCAGCCCGGAAACGCCGCCGAGCGGGAGGCGG
CTGGTCATGCCGATGTTCCCTACACCTTCATACCCGTGACGATGCCAACCATCACCGAGGCGGACGTGCGGGCCTTCCAG
AGGGCCATGGCCGATGCCGGCGGCCCGGTCTTTGCTCATTGCAAGACCGGCACGCGTGCCCTGACCCTGTATGCACTGGG
CGAGGCGCTCGACGGCCGTATGTCATCCCAGGATATGGCGGCCCTCGGACAGAAGCTCGGCATCGACCTGTCGGCGGCGT
CGCGATGGTTCGAAGCGCACAGGCAACTGCGACCGGACGTGAAGGGGTTCTTCGATCCCCGGACAGGAAGCGTGCAATAT
GTGGTTTCGGACCCGGACACCCGAAAATGCGCCATTGTCGATCCGGTTCTTGATTTCGACGAGAAGTCAGGAGCGACCAC
GACGCGCAACGCCGACGCGATGCTTTCCTACATTGCCGAGAACGGGTTGAGCGTCGAATGGATTCTCGACACCCATCCTC
ATGCCGACCATTTTTCGGCCGCGCAGTATCTGAAGGAGAAGACGGGCGCCCCCACCGCGATCGGGGCACCGGTGGTCGAT
GTCCAGCGCCTGTGGCGCGGCATCTACAACTGGCCCGAACTTCGCGTCGACGGCTCGCAGTGGGACAGGCTGTTCTCGGA
TGGCGACACTTTCAAGGTCGGTTCCATGGCGGCGCGCGTGATGTTTTCGCCCGGTCACACCCTGGCGTCGATCACCTACG
TGATCGGCAATGCGGCCTTTGTTCACGACACCATCTTCATGCCTGACAGCGGCACGGCCCGTGCCGATTTTCCCGGTGGT
GACGCTCGCGTCCTGTGGAAATCGATCCAGAAGATCCTGGACCTTCCGGACGAAACCCGCCTGTTTACAGGCCATGATTA
CCAGCCGGGTGGACGCGCGCCGAAATGGGAAAGCACGGTCGGCGAACAGAAGCGCGCCAATGCACATCTGGCCGGCGTGA
ACGAAGAGGCCTTTGCCGGATTGCGAGTGGCGCGTGACCGAACGCTGCCAATGCCGAAACTCATCTTGCATGCCTTGCAG
GTCAACATCCAGGCGGGGCGTCTGCCCGAGCCGGAGCCGAACGGCACGCGCTATCTGAAATTTCCCCTCGACGCATTGCA
AGGAGCAGTGTGGTGA

Upstream 100 bases:

>100_bases
GGCCGGCAACCCGGCCGCGAAATTTCCAGACAGGCACCTTGTACGAATTTCATTATACATTATATGCAATTGTATATTGA
TAGGAAACCAGGTGCTCGAT

Downstream 100 bases:

>100_bases
GCGAGTTCCAGCCTGATGCGGTGAACATGTCGCCCGCCGCCATGGAATCGCGCGCGGGCGAAGTGGCGGCCTTGTTGAAG
ACACTGGCGCATCCAATGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTMIRVNDVLSVGPQPSISEIRSLAGHGFAGMINARPDGEEASQPGNAAEREAAGHADVPYTFIPVTMPTITEADVRAFQ
RAMADAGGPVFAHCKTGTRALTLYALGEALDGRMSSQDMAALGQKLGIDLSAASRWFEAHRQLRPDVKGFFDPRTGSVQY
VVSDPDTRKCAIVDPVLDFDEKSGATTTRNADAMLSYIAENGLSVEWILDTHPHADHFSAAQYLKEKTGAPTAIGAPVVD
VQRLWRGIYNWPELRVDGSQWDRLFSDGDTFKVGSMAARVMFSPGHTLASITYVIGNAAFVHDTIFMPDSGTARADFPGG
DARVLWKSIQKILDLPDETRLFTGHDYQPGGRAPKWESTVGEQKRANAHLAGVNEEAFAGLRVARDRTLPMPKLILHALQ
VNIQAGRLPEPEPNGTRYLKFPLDALQGAVW

Sequences:

>Translated_431_residues
MTMIRVNDVLSVGPQPSISEIRSLAGHGFAGMINARPDGEEASQPGNAAEREAAGHADVPYTFIPVTMPTITEADVRAFQ
RAMADAGGPVFAHCKTGTRALTLYALGEALDGRMSSQDMAALGQKLGIDLSAASRWFEAHRQLRPDVKGFFDPRTGSVQY
VVSDPDTRKCAIVDPVLDFDEKSGATTTRNADAMLSYIAENGLSVEWILDTHPHADHFSAAQYLKEKTGAPTAIGAPVVD
VQRLWRGIYNWPELRVDGSQWDRLFSDGDTFKVGSMAARVMFSPGHTLASITYVIGNAAFVHDTIFMPDSGTARADFPGG
DARVLWKSIQKILDLPDETRLFTGHDYQPGGRAPKWESTVGEQKRANAHLAGVNEEAFAGLRVARDRTLPMPKLILHALQ
VNIQAGRLPEPEPNGTRYLKFPLDALQGAVW
>Mature_430_residues
TMIRVNDVLSVGPQPSISEIRSLAGHGFAGMINARPDGEEASQPGNAAEREAAGHADVPYTFIPVTMPTITEADVRAFQR
AMADAGGPVFAHCKTGTRALTLYALGEALDGRMSSQDMAALGQKLGIDLSAASRWFEAHRQLRPDVKGFFDPRTGSVQYV
VSDPDTRKCAIVDPVLDFDEKSGATTTRNADAMLSYIAENGLSVEWILDTHPHADHFSAAQYLKEKTGAPTAIGAPVVDV
QRLWRGIYNWPELRVDGSQWDRLFSDGDTFKVGSMAARVMFSPGHTLASITYVIGNAAFVHDTIFMPDSGTARADFPGGD
ARVLWKSIQKILDLPDETRLFTGHDYQPGGRAPKWESTVGEQKRANAHLAGVNEEAFAGLRVARDRTLPMPKLILHALQV
NIQAGRLPEPEPNGTRYLKFPLDALQGAVW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=264, Percent_Identity=28.030303030303, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1787158, Length=188, Percent_Identity=30.3191489361702, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=266, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI221330176, Length=262, Percent_Identity=28.2442748091603, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 46892; Mature: 46761

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMIRVNDVLSVGPQPSISEIRSLAGHGFAGMINARPDGEEASQPGNAAEREAAGHADVP
CEEEEECHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCCCC
YTFIPVTMPTITEADVRAFQRAMADAGGPVFAHCKTGTRALTLYALGEALDGRMSSQDMA
EEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEHHHHHCCCCCHHHHH
ALGQKLGIDLSAASRWFEAHRQLRPDVKGFFDPRTGSVQYVVSDPDTRKCAIVDPVLDFD
HHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCCCEEEEECHHHCCC
EKSGATTTRNADAMLSYIAENGLSVEWILDTHPHADHFSAAQYLKEKTGAPTAIGAPVVD
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHH
VQRLWRGIYNWPELRVDGSQWDRLFSDGDTFKVGSMAARVMFSPGHTLASITYVIGNAAF
HHHHHHHHCCCCCEEECHHHHHHHHCCCCCEEHHHHEEEEEECCCCHHHHHHHHHCCEEE
VHDTIFMPDSGTARADFPGGDARVLWKSIQKILDLPDETRLFTGHDYQPGGRAPKWESTV
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHH
GEQKRANAHLAGVNEEAFAGLRVARDRTLPMPKLILHALQVNIQAGRLPEPEPNGTRYLK
CHHHHCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCEEEE
FPLDALQGAVW
ECHHHHCCCCC
>Mature Secondary Structure 
TMIRVNDVLSVGPQPSISEIRSLAGHGFAGMINARPDGEEASQPGNAAEREAAGHADVP
EEEEECHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCCCC
YTFIPVTMPTITEADVRAFQRAMADAGGPVFAHCKTGTRALTLYALGEALDGRMSSQDMA
EEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEHHHHHCCCCCHHHHH
ALGQKLGIDLSAASRWFEAHRQLRPDVKGFFDPRTGSVQYVVSDPDTRKCAIVDPVLDFD
HHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCCCEEEEECHHHCCC
EKSGATTTRNADAMLSYIAENGLSVEWILDTHPHADHFSAAQYLKEKTGAPTAIGAPVVD
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHH
VQRLWRGIYNWPELRVDGSQWDRLFSDGDTFKVGSMAARVMFSPGHTLASITYVIGNAAF
HHHHHHHHCCCCCEEECHHHHHHHHCCCCCEEHHHHEEEEEECCCCHHHHHHHHHCCEEE
VHDTIFMPDSGTARADFPGGDARVLWKSIQKILDLPDETRLFTGHDYQPGGRAPKWESTV
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHH
GEQKRANAHLAGVNEEAFAGLRVARDRTLPMPKLILHALQVNIQAGRLPEPEPNGTRYLK
CHHHHCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCEEEE
FPLDALQGAVW
ECHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]