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The map label for this gene is lgrD [H]

Identifier: 13471859

GI number: 13471859

Start: 1616325

End: 1620302

Strand: Direct

Name: lgrD [H]

Synonym: mlr1968

Alternate gene names: 13471859

Gene position: 1616325-1620302 (Clockwise)

Preceding gene: 13471850

Following gene: 13471860

Centisome position: 22.97

GC content: 64.03

Gene sequence:

>3978_bases
TTGGGCGCCGATTTCGCGCGGGCAGGCCAGCCCTACGAGCGGCTCGACGCGGTCTTCGAAGAGCTCGCTCAAACATTCGC
CACCTTGCCGGCGGTGATCTCCGACGGACGTGCCTGGACGTATCAGGAGCTGGACCGCCGCGCCAACCAGTTCGCCCGTG
TGCTGATCAAGCGCGGCGTGCGGCCTGGCCACCGGGTCGGGCTCATTCTCGACCGCTCGGCGGAGACCTATATCGCCTTG
CTCGCCGTGGTGAAGGCGGGCGCCGCCTTCGTGCCGCTGGCCACCGCCTTTCCGCAAGAGCGCATGGCGCTGATCATCGA
AGACGCCGGCGTCAGCCTGATCGTCACCATCGCCACCTATGCGTCGCGGGCCGACCAGCTGCCGGTTCCCCATGTGCTGA
TCGACAGCGCCGCCGCCGAGATCTCCAAACAGTCCGGCGCGCCGCTGAAGCCGCAAGAGGCGCCGGCGGAAGACATTTGC
TACATCCTGTACACGTCGGGCACGACCGGCAGGCCGAAGGGCGTGGCCATCCGGCACCAGAGCTTCGTCAACTTCATCCG
TGTCGCCGCCGCGTCCTACGGCTACAGGCCGGGCGATCGCGTCTACCAGGGCATGACGATTGCCTTCGACTTTTCCTCCG
AGGAGATTTGGGTGCCGTTCGTCGCCGGCGCGACCGTGGTGCCCGCGCCCGGCCAGATGCCGCTCGTTGGCGAGGAGCTG
GCGGATTTCCTGCGCCACCATGAAATCACCTGCATGGCCTGCAGCCCGACGCTTCTGTCGTCCATGACATCGGATGTGCC
CAGCCTGCGCACACTCCTGGTCGGCGGCGAGGCCTGCCCGCACAATCTGGTGGTGCGCTGGTCGAAGCCGGGGCGGCAGA
TCCTCAACACCTATGGCCCGACCGAGGCGACCGTCACGGCAACGATGGGCGCGCTGACGCCGGACAAGCCGGTCACCATC
GGCGTGCCGCTGCCCACCTATTCCATCGTCATTCTCGATCCGTCGCTGCCGGAACTGGCCGAGCCCAGTGAACTGGGCGA
GATCGGCATTGCCGGCATCGGGCTCGCCGTCGGTTACCTGAACAGGCAAGACCTGACGGAACAGAAGTTCATCGCCGATT
TCATCGGCCTGCCGAACAACCCGTCGCAGCGCATCTACCGCACCGGCGACCTTGGCCGGATCAACGGCGATGGCGAGATC
GAATATGCCGGGCGCATCGACACCCAGGTGAAGATCCGCGGCTATCGTATCGAGCTCGGTGAGATCGAGGCGGTGCTGCT
GGACCAGCCGGAGATCGCACAGGCTGCCGTCACCACCTGGGAGATCGAGCCCGGCCGCGTCGAACTCGTCGCCTATTACG
CGCCCAAGGCCGGACAGCCGGCGCTCTCGCGCGCCGATCTCGCCCAGACGATGAAGCGGCGCCTGCCGGATTACATGGTG
CCCTCCTATCTGGAGGAACTGCCCGCGATCCCGATGACGGTCTCCAACAAGGTGGACCTTCGCCAGCTGCCGAAGCCGAC
AAGCGTGCGGCTTTCCGCCGACCGGGCGATGGTAGCGCCCGGCAATGACGACGAGCGCTTCCTGGCCGAGGCGCTGGGCG
CGGTGCTGAAATTCGACGAGGTGTCGGTCGAGGACAATTTCTTCGACGATCTCGGCGCCAACTCGCTGCTGATGGCGCAT
TTCTGCGCGCGTGTGCGCACCCGCAAGGAATGGGCGACGACGTCCATGCGCGACATCTATCTCCATCCGACGGTGGCGCG
CCTGGCCAAGCACCTCAGCGTCTCGGAAGATATGACGGCCGCCACCAACGAGCCTGTTCTCACCCGCCGGGCGTCGAATT
TTGCCTACTGGACCTGCGGAATGGCGCAGTTGCTGTTCTACGGGGTCTACAGCTATGTCGGCCTGTGGGCGATCAACATC
GGCCTCAACTGGATGTATGAAGCGCTCGACGATCCGCTGCAGCTCTATATCAGATGCGTGGCGCTCTCGTCCGGCGTGTT
CTTCGGCATGACGGGCTTTGCCGTCCTGGCGAAATGGGTGCTCGTCGGCCGCTGGAAGGCCGAAACCTTCCCCATATGGG
GCCTGCGCTACTATCGCTTCTGGGTGGTCAAGACCTTGATCCGCACCGCCCCCGTCGTGCTGTTCCGCGGCAGCCCGCTC
TACAGCCTCTATCTGCAGCTTCTCGGCACCAAACTCGGACACAACGCCGTCATCGAATCCAAATCCGTACCGGTCTGCAC
GGATCTGATCTCGATTGGCGCCAACACCATCCTGCGCAAGGAATCGATGATCCTCGGCTATCGGGCGCAGTCAGGCTATA
TCCACACCGGACCGCTGACCATCGGCCGCGATGCCTTCATCGGCGTGGGCTCCACGCTCGACATCGACACCTCTATTGGC
GACGGCGGCCAGCTCGGCCATTCGTCCTCGCTGCAGCGCGGGCAAAGCATCCCGGACGGCGAACACTGGCATGGGTCACC
GGCCGTGCCGACCACGGCGGACTATTGCAAGGTGCGCAATGTAAATCCTTACCAGGTCCGCCGCTTCCTCTATGAGGCCG
TTCAGCTGGTGGTGCTGTTTGCCATCGTCACCCCACTGCCATTCCTGTTCCAGAGCTATTGGGAAAGCGTCGGCGACGAC
TACCAGGAGACGATCGGCCTTGTCGCGGTCGGCACCACGGTCACGCTCTTTGGCTATATCGCCGTGGCCTTTCTCGTGGC
GACGCTGGTGCCCCGCTTGACAAACCTGGTTCTGAAGCCAGGCCGCACCTACACGCTTTACGGTTTCCGCTACTGGCTGC
AGACCGTCGCCGAATTCACCAGCAACTCGCGCGTGCTGGGGCTGCTGTTCGGCGACAGCTCGGCGATCGTGCATTACATG
CGCGCCATCGGCTGGAACCTCAACAAGGTGGTGCAGACCGGCTCCAATTTCGGCTCCAACCAGCAGCACGAAAACCCGCT
TCTGTGCGAGATCGGCACCGAGACCATGGTGTCGGACGGCCTGTTCATGATCAACATGCACAAATCCGCCTCGGCGTTCC
GGCTCGAGCGGACGCGCATCGGCGAGCGCAACTATCTCGGCAACAACATCTATTATCCGCCGGATGGACGCACGGGCGAC
AACGTCCTGCTCGGCACCAAGGTGATGATCCCCATCGATGGGCCGGTGCGCGAGAATGTCGGGCTCCTGGGTTCGCCTGC
CTTTGAAATCCCCCGCATGGTCAACCGCGACAAGGAACTCATCGCCGGGGTCGACGAGGCGGACCGACGCCAGCGCATCC
CGAACAAGAACCGCCACAATCTGGTGACGATCCTTCTGTTCCTGGCCACGCAATGGGCGATGCTGTTCGCAACGCTGGCG
ATCTGGGATCGCGCGCTGAACTACTACACCGAATGGGCTGAGGTGGCGCTGTTCGTCGCCGTGCTCCTGACCTCGGCGAT
CACCATTCCGTTCTACATCCTGGTCGAACGGGCCAGCCTTGGCTTCGGCCGGCTGAAGCCGCAGATGACGACGATCTACG
ACGTCGCGTTCTGGCGCCACGAACGCCATTGGAAGCTTGCCGATTCGCCGATCGTGCGCCTGTTTGCCGGCACGCCGTTC
CGGCCGATGATCCTGCGCATGCTAGGCGTCAAGGTCGGCAGCCGCGTCTATGATGGCGGAGCTAACCTGACCGAGCGCTC
GCTGGTCGAGATCGGCGACGATGTCACGCTCAACGAAGGCTGCGTCATCCAGGCTCACTCGCTGGAGGAAGGCGCGTTCA
AGTCCGACTATATCCGCATCGGCAAGGGCTGCACGCTCGGACCGTCCGCCTTTGTCCACTACGGCGTCGTGATGGGCGAA
GGATCGGTGGCAGACACAGATTCCTTCGTCATGAAGGGCGAGGAGCTGGAACCCCACTCCATCTGGCGCGGCAACCCGGC
CAAGCTGCATCGCTTCGTGATCCCGGTCACGGACGACGGTGCCAAGGCGTCGGCTTGA

Upstream 100 bases:

>100_bases
TTCACCCGAGACTGGGCTGGCCCAAAACGGGCTGGCAAGCGTCGATGCGCTAGCTAGGCTCGCTCACGATTCGGCATCGG
CTGCTCGCAGCCAGATCCTG

Downstream 100 bases:

>100_bases
AGGCCGGAGAAATCCGCCTCGCCCCTGTGACCAAGGCCAATCGGGCCTTGGTCGCGTCGCTGGAACTGGCGCCGGAGCAA
ATGGATTTTGTCGCTGGCAA

Product: peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1325; Mature: 1324

Protein sequence:

>1325_residues
MGADFARAGQPYERLDAVFEELAQTFATLPAVISDGRAWTYQELDRRANQFARVLIKRGVRPGHRVGLILDRSAETYIAL
LAVVKAGAAFVPLATAFPQERMALIIEDAGVSLIVTIATYASRADQLPVPHVLIDSAAAEISKQSGAPLKPQEAPAEDIC
YILYTSGTTGRPKGVAIRHQSFVNFIRVAAASYGYRPGDRVYQGMTIAFDFSSEEIWVPFVAGATVVPAPGQMPLVGEEL
ADFLRHHEITCMACSPTLLSSMTSDVPSLRTLLVGGEACPHNLVVRWSKPGRQILNTYGPTEATVTATMGALTPDKPVTI
GVPLPTYSIVILDPSLPELAEPSELGEIGIAGIGLAVGYLNRQDLTEQKFIADFIGLPNNPSQRIYRTGDLGRINGDGEI
EYAGRIDTQVKIRGYRIELGEIEAVLLDQPEIAQAAVTTWEIEPGRVELVAYYAPKAGQPALSRADLAQTMKRRLPDYMV
PSYLEELPAIPMTVSNKVDLRQLPKPTSVRLSADRAMVAPGNDDERFLAEALGAVLKFDEVSVEDNFFDDLGANSLLMAH
FCARVRTRKEWATTSMRDIYLHPTVARLAKHLSVSEDMTAATNEPVLTRRASNFAYWTCGMAQLLFYGVYSYVGLWAINI
GLNWMYEALDDPLQLYIRCVALSSGVFFGMTGFAVLAKWVLVGRWKAETFPIWGLRYYRFWVVKTLIRTAPVVLFRGSPL
YSLYLQLLGTKLGHNAVIESKSVPVCTDLISIGANTILRKESMILGYRAQSGYIHTGPLTIGRDAFIGVGSTLDIDTSIG
DGGQLGHSSSLQRGQSIPDGEHWHGSPAVPTTADYCKVRNVNPYQVRRFLYEAVQLVVLFAIVTPLPFLFQSYWESVGDD
YQETIGLVAVGTTVTLFGYIAVAFLVATLVPRLTNLVLKPGRTYTLYGFRYWLQTVAEFTSNSRVLGLLFGDSSAIVHYM
RAIGWNLNKVVQTGSNFGSNQQHENPLLCEIGTETMVSDGLFMINMHKSASAFRLERTRIGERNYLGNNIYYPPDGRTGD
NVLLGTKVMIPIDGPVRENVGLLGSPAFEIPRMVNRDKELIAGVDEADRRQRIPNKNRHNLVTILLFLATQWAMLFATLA
IWDRALNYYTEWAEVALFVAVLLTSAITIPFYILVERASLGFGRLKPQMTTIYDVAFWRHERHWKLADSPIVRLFAGTPF
RPMILRMLGVKVGSRVYDGGANLTERSLVEIGDDVTLNEGCVIQAHSLEEGAFKSDYIRIGKGCTLGPSAFVHYGVVMGE
GSVADTDSFVMKGEELEPHSIWRGNPAKLHRFVIPVTDDGAKASA

Sequences:

>Translated_1325_residues
MGADFARAGQPYERLDAVFEELAQTFATLPAVISDGRAWTYQELDRRANQFARVLIKRGVRPGHRVGLILDRSAETYIAL
LAVVKAGAAFVPLATAFPQERMALIIEDAGVSLIVTIATYASRADQLPVPHVLIDSAAAEISKQSGAPLKPQEAPAEDIC
YILYTSGTTGRPKGVAIRHQSFVNFIRVAAASYGYRPGDRVYQGMTIAFDFSSEEIWVPFVAGATVVPAPGQMPLVGEEL
ADFLRHHEITCMACSPTLLSSMTSDVPSLRTLLVGGEACPHNLVVRWSKPGRQILNTYGPTEATVTATMGALTPDKPVTI
GVPLPTYSIVILDPSLPELAEPSELGEIGIAGIGLAVGYLNRQDLTEQKFIADFIGLPNNPSQRIYRTGDLGRINGDGEI
EYAGRIDTQVKIRGYRIELGEIEAVLLDQPEIAQAAVTTWEIEPGRVELVAYYAPKAGQPALSRADLAQTMKRRLPDYMV
PSYLEELPAIPMTVSNKVDLRQLPKPTSVRLSADRAMVAPGNDDERFLAEALGAVLKFDEVSVEDNFFDDLGANSLLMAH
FCARVRTRKEWATTSMRDIYLHPTVARLAKHLSVSEDMTAATNEPVLTRRASNFAYWTCGMAQLLFYGVYSYVGLWAINI
GLNWMYEALDDPLQLYIRCVALSSGVFFGMTGFAVLAKWVLVGRWKAETFPIWGLRYYRFWVVKTLIRTAPVVLFRGSPL
YSLYLQLLGTKLGHNAVIESKSVPVCTDLISIGANTILRKESMILGYRAQSGYIHTGPLTIGRDAFIGVGSTLDIDTSIG
DGGQLGHSSSLQRGQSIPDGEHWHGSPAVPTTADYCKVRNVNPYQVRRFLYEAVQLVVLFAIVTPLPFLFQSYWESVGDD
YQETIGLVAVGTTVTLFGYIAVAFLVATLVPRLTNLVLKPGRTYTLYGFRYWLQTVAEFTSNSRVLGLLFGDSSAIVHYM
RAIGWNLNKVVQTGSNFGSNQQHENPLLCEIGTETMVSDGLFMINMHKSASAFRLERTRIGERNYLGNNIYYPPDGRTGD
NVLLGTKVMIPIDGPVRENVGLLGSPAFEIPRMVNRDKELIAGVDEADRRQRIPNKNRHNLVTILLFLATQWAMLFATLA
IWDRALNYYTEWAEVALFVAVLLTSAITIPFYILVERASLGFGRLKPQMTTIYDVAFWRHERHWKLADSPIVRLFAGTPF
RPMILRMLGVKVGSRVYDGGANLTERSLVEIGDDVTLNEGCVIQAHSLEEGAFKSDYIRIGKGCTLGPSAFVHYGVVMGE
GSVADTDSFVMKGEELEPHSIWRGNPAKLHRFVIPVTDDGAKASA
>Mature_1324_residues
GADFARAGQPYERLDAVFEELAQTFATLPAVISDGRAWTYQELDRRANQFARVLIKRGVRPGHRVGLILDRSAETYIALL
AVVKAGAAFVPLATAFPQERMALIIEDAGVSLIVTIATYASRADQLPVPHVLIDSAAAEISKQSGAPLKPQEAPAEDICY
ILYTSGTTGRPKGVAIRHQSFVNFIRVAAASYGYRPGDRVYQGMTIAFDFSSEEIWVPFVAGATVVPAPGQMPLVGEELA
DFLRHHEITCMACSPTLLSSMTSDVPSLRTLLVGGEACPHNLVVRWSKPGRQILNTYGPTEATVTATMGALTPDKPVTIG
VPLPTYSIVILDPSLPELAEPSELGEIGIAGIGLAVGYLNRQDLTEQKFIADFIGLPNNPSQRIYRTGDLGRINGDGEIE
YAGRIDTQVKIRGYRIELGEIEAVLLDQPEIAQAAVTTWEIEPGRVELVAYYAPKAGQPALSRADLAQTMKRRLPDYMVP
SYLEELPAIPMTVSNKVDLRQLPKPTSVRLSADRAMVAPGNDDERFLAEALGAVLKFDEVSVEDNFFDDLGANSLLMAHF
CARVRTRKEWATTSMRDIYLHPTVARLAKHLSVSEDMTAATNEPVLTRRASNFAYWTCGMAQLLFYGVYSYVGLWAINIG
LNWMYEALDDPLQLYIRCVALSSGVFFGMTGFAVLAKWVLVGRWKAETFPIWGLRYYRFWVVKTLIRTAPVVLFRGSPLY
SLYLQLLGTKLGHNAVIESKSVPVCTDLISIGANTILRKESMILGYRAQSGYIHTGPLTIGRDAFIGVGSTLDIDTSIGD
GGQLGHSSSLQRGQSIPDGEHWHGSPAVPTTADYCKVRNVNPYQVRRFLYEAVQLVVLFAIVTPLPFLFQSYWESVGDDY
QETIGLVAVGTTVTLFGYIAVAFLVATLVPRLTNLVLKPGRTYTLYGFRYWLQTVAEFTSNSRVLGLLFGDSSAIVHYMR
AIGWNLNKVVQTGSNFGSNQQHENPLLCEIGTETMVSDGLFMINMHKSASAFRLERTRIGERNYLGNNIYYPPDGRTGDN
VLLGTKVMIPIDGPVRENVGLLGSPAFEIPRMVNRDKELIAGVDEADRRQRIPNKNRHNLVTILLFLATQWAMLFATLAI
WDRALNYYTEWAEVALFVAVLLTSAITIPFYILVERASLGFGRLKPQMTTIYDVAFWRHERHWKLADSPIVRLFAGTPFR
PMILRMLGVKVGSRVYDGGANLTERSLVEIGDDVTLNEGCVIQAHSLEEGAFKSDYIRIGKGCTLGPSAFVHYGVVMGEG
SVADTDSFVMKGEELEPHSIWRGNPAKLHRFVIPVTDDGAKASA

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=367, Percent_Identity=28.6103542234332, Blast_Score=121, Evalue=5e-27,
Organism=Homo sapiens, GI42544132, Length=502, Percent_Identity=23.7051792828685, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI58082049, Length=500, Percent_Identity=24.4, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI157311624, Length=500, Percent_Identity=24.4, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI157311622, Length=500, Percent_Identity=24.4, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI38505220, Length=498, Percent_Identity=22.8915662650602, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI115511026, Length=513, Percent_Identity=23.1968810916179, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI13375727, Length=528, Percent_Identity=22.7272727272727, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI122937307, Length=505, Percent_Identity=22.7722772277228, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI42544134, Length=329, Percent_Identity=22.7963525835866, Blast_Score=75, Evalue=6e-13,
Organism=Escherichia coli, GI1786801, Length=640, Percent_Identity=32.96875, Blast_Score=256, Evalue=5e-69,
Organism=Escherichia coli, GI1788107, Length=548, Percent_Identity=22.992700729927, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI145693145, Length=540, Percent_Identity=23.3333333333333, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786810, Length=515, Percent_Identity=25.4368932038835, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI1790505, Length=533, Percent_Identity=24.577861163227, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI221142682, Length=530, Percent_Identity=23.9622641509434, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1786529, Length=534, Percent_Identity=25.0936329588015, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1789201, Length=366, Percent_Identity=24.8633879781421, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=583, Percent_Identity=27.2727272727273, Blast_Score=153, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17550940, Length=553, Percent_Identity=23.5081374321881, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17557194, Length=510, Percent_Identity=22.9411764705882, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=509, Percent_Identity=22.9862475442043, Blast_Score=101, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560140, Length=494, Percent_Identity=22.6720647773279, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=387, Percent_Identity=22.4806201550388, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560308, Length=526, Percent_Identity=21.6730038022814, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985884, Length=370, Percent_Identity=23.2432432432432, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=708, Percent_Identity=23.4463276836158, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319264, Length=544, Percent_Identity=25.5514705882353, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319699, Length=369, Percent_Identity=25.4742547425474, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648676, Length=571, Percent_Identity=26.9702276707531, Blast_Score=166, Evalue=8e-41,
Organism=Drosophila melanogaster, GI62472339, Length=551, Percent_Identity=23.5934664246824, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667955, Length=551, Percent_Identity=23.5934664246824, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24667959, Length=393, Percent_Identity=24.4274809160305, Blast_Score=88, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24582852, Length=306, Percent_Identity=28.4313725490196, Blast_Score=80, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355225, Length=481, Percent_Identity=25.987525987526, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 146063; Mature: 145931

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADFARAGQPYERLDAVFEELAQTFATLPAVISDGRAWTYQELDRRANQFARVLIKRGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
RPGHRVGLILDRSAETYIALLAVVKAGAAFVPLATAFPQERMALIIEDAGVSLIVTIATY
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEHHHHCCCCCCEEEEEECCCCEEEEEEHHH
ASRADQLPVPHVLIDSAAAEISKQSGAPLKPQEAPAEDICYILYTSGTTGRPKGVAIRHQ
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEHH
SFVNFIRVAAASYGYRPGDRVYQGMTIAFDFSSEEIWVPFVAGATVVPAPGQMPLVGEEL
HHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCEEEEEECCCEEECCCCCCCCCHHHH
ADFLRHHEITCMACSPTLLSSMTSDVPSLRTLLVGGEACPHNLVVRWSKPGRQILNTYGP
HHHHHHCCEEEEECCHHHHHHHHCCCHHHHHHEECCCCCCCCEEEEECCCCHHHHHHCCC
TEATVTATMGALTPDKPVTIGVPLPTYSIVILDPSLPELAEPSELGEIGIAGIGLAVGYL
CCEEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHC
NRQDLTEQKFIADFIGLPNNPSQRIYRTGDLGRINGDGEIEYAGRIDTQVKIRGYRIELG
CHHCCHHHHHHHHHHCCCCCCHHCEEECCCCEEECCCCCEEECCCCCCEEEEEEEEEEEC
EIEAVLLDQPEIAQAAVTTWEIEPGRVELVAYYAPKAGQPALSRADLAQTMKRRLPDYMV
CEEEEEECCCCHHHHHEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
PSYLEELPAIPMTVSNKVDLRQLPKPTSVRLSADRAMVAPGNDDERFLAEALGAVLKFDE
HHHHHHCCCCCEEECCCCCHHHCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHCC
VSVEDNFFDDLGANSLLMAHFCARVRTRKEWATTSMRDIYLHPTVARLAKHLSVSEDMTA
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCC
ATNEPVLTRRASNFAYWTCGMAQLLFYGVYSYVGLWAINIGLNWMYEALDDPLQLYIRCV
CCCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCHHHHHHHHH
ALSSGVFFGMTGFAVLAKWVLVGRWKAETFPIWGLRYYRFWVVKTLIRTAPVVLFRGSPL
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHCCEEEECCCHH
YSLYLQLLGTKLGHNAVIESKSVPVCTDLISIGANTILRKESMILGYRAQSGYIHTGPLT
HHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHCCHHHEECCCEEEEEECCCCEEEECCEE
IGRDAFIGVGSTLDIDTSIGDGGQLGHSSSLQRGQSIPDGEHWHGSPAVPTTADYCKVRN
ECCCCEEECCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHEECC
VNPYQVRRFLYEAVQLVVLFAIVTPLPFLFQSYWESVGDDYQETIGLVAVGTTVTLFGYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCEEEEHHHHHHHHHH
AVAFLVATLVPRLTNLVLKPGRTYTLYGFRYWLQTVAEFTSNSRVLGLLFGDSSAIVHYM
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
RAIGWNLNKVVQTGSNFGSNQQHENPLLCEIGTETMVSDGLFMINMHKSASAFRLERTRI
HHHCCCHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHCCEEEEEECCCCCHHHHHHHHC
GERNYLGNNIYYPPDGRTGDNVLLGTKVMIPIDGPVRENVGLLGSPAFEIPRMVNRDKEL
CCCCCCCCCCEECCCCCCCCCEEEEEEEEEECCCCHHHCCCCCCCCHHHHHHHHCCCHHH
IAGVDEADRRQRIPNKNRHNLVTILLFLATQWAMLFATLAIWDRALNYYTEWAEVALFVA
HCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLTSAITIPFYILVERASLGFGRLKPQMTTIYDVAFWRHERHWKLADSPIVRLFAGTPF
HHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCH
RPMILRMLGVKVGSRVYDGGANLTERSLVEIGDDVTLNEGCVIQAHSLEEGAFKSDYIRI
HHHHHHHHHHHHCCEEECCCCCCCHHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCEEE
GKGCTLGPSAFVHYGVVMGEGSVADTDSFVMKGEELEPHSIWRGNPAKLHRFVIPVTDDG
CCCCCCCCHHHHEEEEEECCCCCCCCCHHEECCCCCCCCCCCCCCHHHEEEEEEEEECCC
AKASA
CCCCC
>Mature Secondary Structure 
GADFARAGQPYERLDAVFEELAQTFATLPAVISDGRAWTYQELDRRANQFARVLIKRGV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
RPGHRVGLILDRSAETYIALLAVVKAGAAFVPLATAFPQERMALIIEDAGVSLIVTIATY
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEHHHHCCCCCCEEEEEECCCCEEEEEEHHH
ASRADQLPVPHVLIDSAAAEISKQSGAPLKPQEAPAEDICYILYTSGTTGRPKGVAIRHQ
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEHH
SFVNFIRVAAASYGYRPGDRVYQGMTIAFDFSSEEIWVPFVAGATVVPAPGQMPLVGEEL
HHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCEEEEEECCCEEECCCCCCCCCHHHH
ADFLRHHEITCMACSPTLLSSMTSDVPSLRTLLVGGEACPHNLVVRWSKPGRQILNTYGP
HHHHHHCCEEEEECCHHHHHHHHCCCHHHHHHEECCCCCCCCEEEEECCCCHHHHHHCCC
TEATVTATMGALTPDKPVTIGVPLPTYSIVILDPSLPELAEPSELGEIGIAGIGLAVGYL
CCEEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHC
NRQDLTEQKFIADFIGLPNNPSQRIYRTGDLGRINGDGEIEYAGRIDTQVKIRGYRIELG
CHHCCHHHHHHHHHHCCCCCCHHCEEECCCCEEECCCCCEEECCCCCCEEEEEEEEEEEC
EIEAVLLDQPEIAQAAVTTWEIEPGRVELVAYYAPKAGQPALSRADLAQTMKRRLPDYMV
CEEEEEECCCCHHHHHEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
PSYLEELPAIPMTVSNKVDLRQLPKPTSVRLSADRAMVAPGNDDERFLAEALGAVLKFDE
HHHHHHCCCCCEEECCCCCHHHCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHCC
VSVEDNFFDDLGANSLLMAHFCARVRTRKEWATTSMRDIYLHPTVARLAKHLSVSEDMTA
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCC
ATNEPVLTRRASNFAYWTCGMAQLLFYGVYSYVGLWAINIGLNWMYEALDDPLQLYIRCV
CCCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCHHHHHHHHH
ALSSGVFFGMTGFAVLAKWVLVGRWKAETFPIWGLRYYRFWVVKTLIRTAPVVLFRGSPL
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHCCEEEECCCHH
YSLYLQLLGTKLGHNAVIESKSVPVCTDLISIGANTILRKESMILGYRAQSGYIHTGPLT
HHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHCCHHHEECCCEEEEEECCCCEEEECCEE
IGRDAFIGVGSTLDIDTSIGDGGQLGHSSSLQRGQSIPDGEHWHGSPAVPTTADYCKVRN
ECCCCEEECCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHEECC
VNPYQVRRFLYEAVQLVVLFAIVTPLPFLFQSYWESVGDDYQETIGLVAVGTTVTLFGYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCEEEEHHHHHHHHHH
AVAFLVATLVPRLTNLVLKPGRTYTLYGFRYWLQTVAEFTSNSRVLGLLFGDSSAIVHYM
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
RAIGWNLNKVVQTGSNFGSNQQHENPLLCEIGTETMVSDGLFMINMHKSASAFRLERTRI
HHHCCCHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHCCEEEEEECCCCCHHHHHHHHC
GERNYLGNNIYYPPDGRTGDNVLLGTKVMIPIDGPVRENVGLLGSPAFEIPRMVNRDKEL
CCCCCCCCCCEECCCCCCCCCEEEEEEEEEECCCCHHHCCCCCCCCHHHHHHHHCCCHHH
IAGVDEADRRQRIPNKNRHNLVTILLFLATQWAMLFATLAIWDRALNYYTEWAEVALFVA
HCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLTSAITIPFYILVERASLGFGRLKPQMTTIYDVAFWRHERHWKLADSPIVRLFAGTPF
HHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCH
RPMILRMLGVKVGSRVYDGGANLTERSLVEIGDDVTLNEGCVIQAHSLEEGAFKSDYIRI
HHHHHHHHHHHHCCEEECCCCCCCHHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCEEE
GKGCTLGPSAFVHYGVVMGEGSVADTDSFVMKGEELEPHSIWRGNPAKLHRFVIPVTDDG
CCCCCCCCHHHHEEEEEECCCCCCCCCHHEECCCCCCCCCCCCCCHHHEEEEEEEEECCC
AKASA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA