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The map label for this gene is yezC [H]

Identifier: 13471754

GI number: 13471754

Start: 1509544

End: 1510026

Strand: Direct

Name: yezC [H]

Synonym: mlr1825

Alternate gene names: 13471754

Gene position: 1509544-1510026 (Clockwise)

Preceding gene: 13471752

Following gene: 13471755

Centisome position: 21.45

GC content: 67.08

Gene sequence:

>483_bases
ATGAAGACCAGCGATGAGCGCGCGCCGCTCGACCCGACCGACATCGCCATCATAGAGGCCATGCAGGAAAACGGCCGCAT
CGGCATATCGGAGCTTGGCCGCCGGGTCGGACTGTCGCAGCCGGCCACCTCCGAGCGGGTCAAGCGGCTGGAGGAGCGCG
GCATCATTGCCGGCTACACCGCGGTGATCGACCCGGCCGCCCTTGGCCTCGGCATGATGGCGATCATCCGGGTGCGCACC
ACGCATGAGCACATCCGCCCCTGCCTGAAGCAGTTCGCCGAAATGCCCGAGATTACCGAAGTGCACCGGCTGACCGGCGA
GGACTGCTTCATCCTGAAAGTGCTCGTCCCCTCGCCCGCCCACCTTGAAACGATCGTCGACGCCGTGGCGCGCCGTGGCG
CGGTCACCACCGCACTGGTGCTGCGCAGCGAGACGCCAAAGCCCATCGGCCGCGAGCTGATCCGCGCGAACACGGTTTCG
TGA

Upstream 100 bases:

>100_bases
GCTCCTATCGATCACAGGTGCATGGTGGCGTCTTGAATTGCCGTCGGGAATGGGAAATCATCGGAGAAATCACGTCCTTA
CCGATGGATTCAAGGTGACC

Downstream 100 bases:

>100_bases
GGGCCGAACCGGTCATCAATCCGTTGCAGTGCGGACCTAACTGCTGAGCGAACTGGACCTGGAATTCATGACGACAGGAC
GAGGCAAACGCCTGATGATC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKTSDERAPLDPTDIAIIEAMQENGRIGISELGRRVGLSQPATSERVKRLEERGIIAGYTAVIDPAALGLGMMAIIRVRT
THEHIRPCLKQFAEMPEITEVHRLTGEDCFILKVLVPSPAHLETIVDAVARRGAVTTALVLRSETPKPIGRELIRANTVS

Sequences:

>Translated_160_residues
MKTSDERAPLDPTDIAIIEAMQENGRIGISELGRRVGLSQPATSERVKRLEERGIIAGYTAVIDPAALGLGMMAIIRVRT
THEHIRPCLKQFAEMPEITEVHRLTGEDCFILKVLVPSPAHLETIVDAVARRGAVTTALVLRSETPKPIGRELIRANTVS
>Mature_160_residues
MKTSDERAPLDPTDIAIIEAMQENGRIGISELGRRVGLSQPATSERVKRLEERGIIAGYTAVIDPAALGLGMMAIIRVRT
THEHIRPCLKQFAEMPEITEVHRLTGEDCFILKVLVPSPAHLETIVDAVARRGAVTTALVLRSETPKPIGRELIRANTVS

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=113, Percent_Identity=36.283185840708, Blast_Score=73, Evalue=7e-15,
Organism=Escherichia coli, GI87081742, Length=111, Percent_Identity=31.5315315315315, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR000835
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17511; Mature: 17511

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSDERAPLDPTDIAIIEAMQENGRIGISELGRRVGLSQPATSERVKRLEERGIIAGYT
CCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEECHH
AVIDPAALGLGMMAIIRVRTTHEHIRPCLKQFAEMPEITEVHRLTGEDCFILKVLVPSPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCH
HLETIVDAVARRGAVTTALVLRSETPKPIGRELIRANTVS
HHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKTSDERAPLDPTDIAIIEAMQENGRIGISELGRRVGLSQPATSERVKRLEERGIIAGYT
CCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEECHH
AVIDPAALGLGMMAIIRVRTTHEHIRPCLKQFAEMPEITEVHRLTGEDCFILKVLVPSPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCH
HLETIVDAVARRGAVTTALVLRSETPKPIGRELIRANTVS
HHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]