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The map label for this gene is lrp [H]

Identifier: 13471599

GI number: 13471599

Start: 1347339

End: 1347797

Strand: Direct

Name: lrp [H]

Synonym: mlr1619

Alternate gene names: 13471599

Gene position: 1347339-1347797 (Clockwise)

Preceding gene: 13471596

Following gene: 13471604

Centisome position: 19.15

GC content: 61.44

Gene sequence:

>459_bases
GTGCAGCAGAAGATAGCCGACGATTTCGACCTGAGGATTCTGCGCGAATTGCGTGATGACGCCCGCATCACCAACAACGA
GCTCGCCGAGCGCATCGGCCTGTCGCCGTCGCCTTGTCTCAGGCGCGTGCGGCGGCTGGAGGAGACGGGCGTCATCAGGG
GTTACACCACGCTGGTCGATCCCGCCGCCTTCGGCTGGAGCATGGTCGCCATCGCCACCATCCGGCTCAGCCGGCAGAAC
GAGGACGAGATCGTCATGTTCGAGGAGGCGATCCGCGGCTGGGACGAGGTGCTGGAATGCCATCTCGTCACCGGTTCGCG
CGATTATGTGCTGAAGGTGGTGACTGGCAACCTCGAACAATACGAGCGCTTCATCAAGGAAAAGATCGCGCGGCTGAAAT
GCGTCGCCTCGATCGAGACCAGCTTCGTCATGAACACCATAAAGGAACGGCGCCTCTGA

Upstream 100 bases:

>100_bases
ATGTCGTGCCGCAATTTATGCGATCTAGATCGGCCAGTCCTTGCTATTTTCGGCCGCGCATGGCTGCTTGCCGGCAAGAA
ATTGCCTGGAGTGATAGAAA

Downstream 100 bases:

>100_bases
CATTTGGCCAGGGGCGCCGCTCCATCTTGTCGGTTGAGCATGATCTTTTGCGGATCACGCTCGCGCAGGTTTACTTAATC
GCCTTGTCGGTGATCGCGGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MQQKIADDFDLRILRELRDDARITNNELAERIGLSPSPCLRRVRRLEETGVIRGYTTLVDPAAFGWSMVAIATIRLSRQN
EDEIVMFEEAIRGWDEVLECHLVTGSRDYVLKVVTGNLEQYERFIKEKIARLKCVASIETSFVMNTIKERRL

Sequences:

>Translated_152_residues
MQQKIADDFDLRILRELRDDARITNNELAERIGLSPSPCLRRVRRLEETGVIRGYTTLVDPAAFGWSMVAIATIRLSRQN
EDEIVMFEEAIRGWDEVLECHLVTGSRDYVLKVVTGNLEQYERFIKEKIARLKCVASIETSFVMNTIKERRL
>Mature_152_residues
MQQKIADDFDLRILRELRDDARITNNELAERIGLSPSPCLRRVRRLEETGVIRGYTTLVDPAAFGWSMVAIATIRLSRQN
EDEIVMFEEAIRGWDEVLECHLVTGSRDYVLKVVTGNLEQYERFIKEKIARLKCVASIETSFVMNTIKERRL

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=41.7808219178082, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI87081742, Length=142, Percent_Identity=27.4647887323944, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17632; Mature: 17632

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKIADDFDLRILRELRDDARITNNELAERIGLSPSPCLRRVRRLEETGVIRGYTTLVD
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHC
PAAFGWSMVAIATIRLSRQNEDEIVMFEEAIRGWDEVLECHLVTGSRDYVLKVVTGNLEQ
HHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHEECCCCEEEEEEECCHHH
YERFIKEKIARLKCVASIETSFVMNTIKERRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQKIADDFDLRILRELRDDARITNNELAERIGLSPSPCLRRVRRLEETGVIRGYTTLVD
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHC
PAAFGWSMVAIATIRLSRQNEDEIVMFEEAIRGWDEVLECHLVTGSRDYVLKVVTGNLEQ
HHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHEECCCCEEEEEEECCHHH
YERFIKEKIARLKCVASIETSFVMNTIKERRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]