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The map label for this gene is catB2 [H]

Identifier: 13471529

GI number: 13471529

Start: 1268665

End: 1269306

Strand: Reverse

Name: catB2 [H]

Synonym: mll1530

Alternate gene names: 13471529

Gene position: 1269306-1268665 (Counterclockwise)

Preceding gene: 13471530

Following gene: 13471528

Centisome position: 18.04

GC content: 64.02

Gene sequence:

>642_bases
ATGGACCGCACCGAAAACCTCGTCCTGAAAGACCCAGAGCCGCGCATCCATCCGACCGCGGAGCTGAAGGCGTGCAAGCT
CGGCCGCTACGCCTTGATCGGTGAACGGGTGGTGCTGCGCGAGGTGAGCGTCGGCGACTTCTCCTATTTCGAGCGCCATT
CGGAAGCCATCTACACAACCATCGGCAAATTCTGCTCGATTGCCGCCAACAGCCGCATCAATGCGCTGGAGCATCCGATC
GAGCGGCTGACCCAGCACAAGGTCAGCTATCGGCCGAACGAGTATTTTCGATGGCTGGGCGTCGATGCGGCGTTCCGCGA
GCGGCGGCAGGCGAAGGCCGTGACCATCGGCCATGACGTCTGGATCGGCCACGGCGCGGTGATCATGCCCGGCATCACGA
TCGGCAATGGCGCGGTCATCGGCGCCAATGCGGTGGTGACGCAGGACGTGCCGTCTTACACGATCGTCGCCGGCGTGCCG
GCAAAACCGCTCCGGCCGCGCTTTGCTCCCGACATAGCGGCGCGGATCGAAGCACTCGCCTGGTGGGACTGGCCGGTCGA
GAAACTCGCCAGGGCGGTTCCCGACATCCAGTCCATGCCGATCGAGGCCTTCCTCGATCGTTGGGAAAACGACGCCGTTT
AG

Upstream 100 bases:

>100_bases
GCAAGCCGAAATAGGTCGGTGGGCGTCTTTTTGTGCTGATCGGCCCCACGGGCAATTGCTCCTGCCTTGCGGGAGCAATT
GCCCTGAAGTAAAGCGCCGC

Downstream 100 bases:

>100_bases
GCTTTCGCTGACAACGGTTTGGCCCTGGCCGTCACCGCCGCGCAGGCCATCATCCGCGCTCTCTGAACTGAAACCCCTTC
CGCCATGCGGGGGTGGCGCG

Product: acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDRTENLVLKDPEPRIHPTAELKACKLGRYALIGERVVLREVSVGDFSYFERHSEAIYTTIGKFCSIAANSRINALEHPI
ERLTQHKVSYRPNEYFRWLGVDAAFRERRQAKAVTIGHDVWIGHGAVIMPGITIGNGAVIGANAVVTQDVPSYTIVAGVP
AKPLRPRFAPDIAARIEALAWWDWPVEKLARAVPDIQSMPIEAFLDRWENDAV

Sequences:

>Translated_213_residues
MDRTENLVLKDPEPRIHPTAELKACKLGRYALIGERVVLREVSVGDFSYFERHSEAIYTTIGKFCSIAANSRINALEHPI
ERLTQHKVSYRPNEYFRWLGVDAAFRERRQAKAVTIGHDVWIGHGAVIMPGITIGNGAVIGANAVVTQDVPSYTIVAGVP
AKPLRPRFAPDIAARIEALAWWDWPVEKLARAVPDIQSMPIEAFLDRWENDAV
>Mature_213_residues
MDRTENLVLKDPEPRIHPTAELKACKLGRYALIGERVVLREVSVGDFSYFERHSEAIYTTIGKFCSIAANSRINALEHPI
ERLTQHKVSYRPNEYFRWLGVDAAFRERRQAKAVTIGHDVWIGHGAVIMPGITIGNGAVIGANAVVTQDVPSYTIVAGVP
AKPLRPRFAPDIAARIEALAWWDWPVEKLARAVPDIQSMPIEAFLDRWENDAV

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=129, Percent_Identity=32.5581395348837, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788345, Length=56, Percent_Identity=48.2142857142857, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786664, Length=105, Percent_Identity=35.2380952380952, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23866; Mature: 23866

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTENLVLKDPEPRIHPTAELKACKLGRYALIGERVVLREVSVGDFSYFERHSEAIYTT
CCCCCCCEEECCCCCCCCCHHHHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHH
IGKFCSIAANSRINALEHPIERLTQHKVSYRPNEYFRWLGVDAAFRERRQAKAVTIGHDV
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCHHHHHHHHHCEEEECCEE
WIGHGAVIMPGITIGNGAVIGANAVVTQDVPSYTIVAGVPAKPLRPRFAPDIAARIEALA
EECCCEEEECCEEECCCEEECCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
WWDWPVEKLARAVPDIQSMPIEAFLDRWENDAV
CCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MDRTENLVLKDPEPRIHPTAELKACKLGRYALIGERVVLREVSVGDFSYFERHSEAIYTT
CCCCCCCEEECCCCCCCCCHHHHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHH
IGKFCSIAANSRINALEHPIERLTQHKVSYRPNEYFRWLGVDAAFRERRQAKAVTIGHDV
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCHHHHHHHHHCEEEECCEE
WIGHGAVIMPGITIGNGAVIGANAVVTQDVPSYTIVAGVPAKPLRPRFAPDIAARIEALA
EECCCEEEECCEEECCCEEECCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
WWDWPVEKLARAVPDIQSMPIEAFLDRWENDAV
CCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]