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The map label for this gene is cobK [H]

Identifier: 13471416

GI number: 13471416

Start: 1157853

End: 1158614

Strand: Reverse

Name: cobK [H]

Synonym: mll1382

Alternate gene names: 13471416

Gene position: 1158614-1157853 (Counterclockwise)

Preceding gene: 13471424

Following gene: 13471407

Centisome position: 16.47

GC content: 67.45

Gene sequence:

>762_bases
ATGACCCACCGCATTCTGATCCTCGGCGGCACCACGGAAGCCCGGCAACTGGCTGGCAAGCTGGCGGTACGAACCTCGGT
CACGCTGTCGCTGGCCGGCCGCACCGAAAGCCCCGTCGCGCAACGCGTGCCCGTGCGAAGCGGAGGCTTTGGCGGCGCAG
AGGGTCTGGCCGCCTATCTCCGGGAGGCCGGCACCGATCTGATGATCGACGCCACGCATCCTTATGCGGCGCGAATCTCC
GCCAATGCCGCGCAAGCGGCGCGGCTGACCGGTGTGCCGATCGTTGCTTTGCGCCGTCCCGGCTGGGAGCCAGTCGAAGG
CGACCGCTGGACTGAGGTCGATACAACAGGCGAGGCCGCGCAAGCGCTTGGTCCGGCGCCGCGGCGTGTCTTCCTGGCGC
TTGGCCGGCAAGAGGTTGCCGCTTTCGAAGCAGCGCCCCAGCATCACTACCTCATTCGCAGCGTCGATCCCGTCGAGCCG
AAGCTGGCCGTGCCGGATGCGAGCTATCTGCTGGCGCGCGGGCCGTTTGGCGAGGCGGACGAACGCGCGCTGCTCGAAAA
GCATCGCATCGAATTGGTCGTCTCCAAGAACAGCGGCGGCGCTGCCACGTACGGCAAGATTGCCGCCGCGCGAGCGCTTG
GCATCGACGTGGTCATGGTCCGCAGGCCGACTTTGCCGGACGTGCCTTCGGCTGAAACCGTCGATGAACTCGCCGCGATG
GTCGATCATTTTGTCGAGCCCGCTGCGGAGCGCGGGGTGTAG

Upstream 100 bases:

>100_bases
CTGCTTGGCCTCGTCGCCGAGACCCGCTAAACCGTCCTCGCCGATGCCGATCACCGTCAGCCATTTCGGTCCGGCGCCGC
GCGAACTTTCAGCAGGCATG

Downstream 100 bases:

>100_bases
ACCAGCGCCCGTTTATCGCCGCGCTTGATGATGCGTGTTTCCGGCGAGCCGATGATGATGCAGGTCGCCATGTCGGCCTT
TTGCGCGTCGACGTCAGCCA

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTHRILILGGTTEARQLAGKLAVRTSVTLSLAGRTESPVAQRVPVRSGGFGGAEGLAAYLREAGTDLMIDATHPYAARIS
ANAAQAARLTGVPIVALRRPGWEPVEGDRWTEVDTTGEAAQALGPAPRRVFLALGRQEVAAFEAAPQHHYLIRSVDPVEP
KLAVPDASYLLARGPFGEADERALLEKHRIELVVSKNSGGAATYGKIAAARALGIDVVMVRRPTLPDVPSAETVDELAAM
VDHFVEPAAERGV

Sequences:

>Translated_253_residues
MTHRILILGGTTEARQLAGKLAVRTSVTLSLAGRTESPVAQRVPVRSGGFGGAEGLAAYLREAGTDLMIDATHPYAARIS
ANAAQAARLTGVPIVALRRPGWEPVEGDRWTEVDTTGEAAQALGPAPRRVFLALGRQEVAAFEAAPQHHYLIRSVDPVEP
KLAVPDASYLLARGPFGEADERALLEKHRIELVVSKNSGGAATYGKIAAARALGIDVVMVRRPTLPDVPSAETVDELAAM
VDHFVEPAAERGV
>Mature_252_residues
THRILILGGTTEARQLAGKLAVRTSVTLSLAGRTESPVAQRVPVRSGGFGGAEGLAAYLREAGTDLMIDATHPYAARISA
NAAQAARLTGVPIVALRRPGWEPVEGDRWTEVDTTGEAAQALGPAPRRVFLALGRQEVAAFEAAPQHHYLIRSVDPVEPK
LAVPDASYLLARGPFGEADERALLEKHRIELVVSKNSGGAATYGKIAAARALGIDVVMVRRPTLPDVPSAETVDELAAMV
DHFVEPAAERGV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26760; Mature: 26629

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRILILGGTTEARQLAGKLAVRTSVTLSLAGRTESPVAQRVPVRSGGFGGAEGLAAYL
CCEEEEEEECCHHHHHHHHHHHEEEEEEEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHH
REAGTDLMIDATHPYAARISANAAQAARLTGVPIVALRRPGWEPVEGDRWTEVDTTGEAA
HHCCCCEEEECCCCCEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHH
QALGPAPRRVFLALGRQEVAAFEAAPQHHYLIRSVDPVEPKLAVPDASYLLARGPFGEAD
HHCCCCCHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCHHEEEECCCCCCH
ERALLEKHRIELVVSKNSGGAATYGKIAAARALGIDVVMVRRPTLPDVPSAETVDELAAM
HHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHH
VDHFVEPAAERGV
HHHHHCHHHHCCC
>Mature Secondary Structure 
THRILILGGTTEARQLAGKLAVRTSVTLSLAGRTESPVAQRVPVRSGGFGGAEGLAAYL
CEEEEEEECCHHHHHHHHHHHEEEEEEEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHH
REAGTDLMIDATHPYAARISANAAQAARLTGVPIVALRRPGWEPVEGDRWTEVDTTGEAA
HHCCCCEEEECCCCCEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHH
QALGPAPRRVFLALGRQEVAAFEAAPQHHYLIRSVDPVEPKLAVPDASYLLARGPFGEAD
HHCCCCCHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCHHEEEECCCCCCH
ERALLEKHRIELVVSKNSGGAATYGKIAAARALGIDVVMVRRPTLPDVPSAETVDELAAM
HHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHH
VDHFVEPAAERGV
HHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]