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The map label for this gene is nuoL [H]

Identifier: 13471395

GI number: 13471395

Start: 1134719

End: 1136692

Strand: Reverse

Name: nuoL [H]

Synonym: mll1355

Alternate gene names: 13471395

Gene position: 1136692-1134719 (Counterclockwise)

Preceding gene: 13471396

Following gene: 13471394

Centisome position: 16.16

GC content: 62.87

Gene sequence:

>1974_bases
ATGTATCAGGCCATCGTCTTCCTTCCCCTGCTCGGCTTCCTGATCGTCGGCCTGTTCGGCACGTCGCTCGGCGCCAAGGC
GTCCGAATACATCACCTCCGGTTTCCTGGTGATTTCGGCTGTGCTGTCGTGGGTCGCCTTTTTCAGCGTCGGCTTCGGCC
ATGGCGAGGTGTTCACCGTGCCGGTGCTGCACTGGATCCAGTCCGGCGGGCTGGACGCCTCCTGGGCGCTGCGCATCGAC
ACGCTGACGGTGGTGATGCTGGTGGTGGTCAACACCGTGTCGGCGCTGGTCCATATCTATTCGATCGGCTACATGCACCA
CGATCCGAACCGGCCGCGCTTCTTCGCCTACCTGTCGCTGTTCACCTTCGCGATGCTGATGCTGGTGACGGCCGATAACC
TCGTGCAGATGTTCTTCGGCTGGGAAGGCGTGGGTCTCGCCTCCTACCTGCTGATCGGTTTCTGGTACAAGAAGCCGTCG
GCCAATGCCGCGGCCATCAAGGCCTTCGTCGTCAACCGCGTCGGCGATTTCGGCTTCGCGCTCGGCATTTTCGGCGTGTT
CGTGCTGTTCGGGTCGGTCAATCTCGGCACCATCTTCGCCAATGCGGCGACGTTCGCTCCGGCCGAAGGCGCGCCGCAAG
GTGCTGCCGTGCTGACCTTCCTTGGCCATGCGCTGGACAAGCAGGCGGCCATGACCGTCGTCTGCCTGCTCCTGTTCATG
GGCGCCATGGGCAAGTCGGCGCAGGTGCCGCTGCACACCTGGCTGCCGGACGCCATGGAAGGCCCGACGCCGGTCTCCGC
ACTCATCCACGCCGCTACCATGGTGACGGCGGGCGTGTTCATGCTGGCGCGGCTGTCACCGCTGTTCGAACTGTCGCATT
CGGCGCTGACCGTGGTGACCTTCATCGGCGCCTTCACCGCCTTCTTCGCGGCGACCGTCGGTCTGGTCCAGAACGACATC
AAGCGCGTCATCGCCTATTCGACGTGCTCGCAGCTCGGCTACATGTTCGTGGCGCTCGGCGTCGGCGCCTATGGCGCGGC
GATCTTCCATCTGTTCACGCATGCCTTCTTCAAGGCGCTGCTGTTCCTCGGTTCCGGCTCGGTCATCCATGCCGTCTCCG
ACGAGCAGGACATGCGCAAGATGGGCGGTCTGAGGTCGCTGATCCCGACCACCTACTGGATGATGGTGATCGGCACGCTG
GCCTTGACCGGCGTCGGCATTCCTGTGACCGTCATCGGCACCGCCGGCTTCTTCTCCAAGGACGCCATCATCGAAAGCGC
CTTTGCCGGCCACAATTCGGTTGCCGGCCTCGCCTTTGTGCTGCTGGTCATCGCCGCCTGCTTCACCTCCTTCTACTCCT
GGCGGCTGATCTTCATGACCTTCCACGGCGAGCCCAGGGCGAGCCATGAGGTGATGCATCATGTGCATGAATCGCCGCCG
GTGATGCTGGTGCCGCTGTTCGTGCTGGCCGCCGGCGCGCTGTTTGCCGGCATCATTTTCCACAATTCCTTCATCGGCGA
AGGCTATGCCGAGTTCTGGAAGGCGTCGCTGTTCACGCTGCCGGACAATCACATCCTGCACGAAATCCACGAACTGCCGC
TGTGGGTCGAACTGGCGCCCTTCATCGCCATGCTGATCGGCTTCGCGGTGGCCTGGAAGTTCTACATCCGCTCACCGGAA
TTGCCCCGGAGCGTCGCCGCCAACCATCGCTTGCTCTACGCCTTCCTGCTCAACAAGTGGTATTTCGACGAACTCTACGA
CTTCCTGTTCGTGCGGCCCGCCAAGCGCCTTGGCCATTTCCTGTGGAAGACCGGTGACGGCACCGTCATCGACGGGCTTG
GGCCGGATGGCATTTCGGCGCGCGTCGTCGATGTCACCAACCGCGTCGTCAAGCTGCAAACCGGCTACCTCTACCACTAT
GCCTTCGCCATGCTGATCGGCGTTGCCGCACTCGTCACCTGGATGATGCTCTGA

Upstream 100 bases:

>100_bases
GAAGCCGCAATCGGACTTGCCATTCTCGTCGTCTTCTTCCGCAACCGCGGCTCGATCGCGGTCGAAGACGTGAACATGAT
GAAGGGTTGACGGAACCACC

Downstream 100 bases:

>100_bases
TGACCGCCTGGCCAATCCTCTCGCTGGTCACCTTCCTGCCGCTGGTTGGTGTGCTGCTTATCCTGTTCATCCGGGATGAT
AGCGAAAACGCGCGCCGCAA

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MYQAIVFLPLLGFLIVGLFGTSLGAKASEYITSGFLVISAVLSWVAFFSVGFGHGEVFTVPVLHWIQSGGLDASWALRID
TLTVVMLVVVNTVSALVHIYSIGYMHHDPNRPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPS
ANAAAIKAFVVNRVGDFGFALGIFGVFVLFGSVNLGTIFANAATFAPAEGAPQGAAVLTFLGHALDKQAAMTVVCLLLFM
GAMGKSAQVPLHTWLPDAMEGPTPVSALIHAATMVTAGVFMLARLSPLFELSHSALTVVTFIGAFTAFFAATVGLVQNDI
KRVIAYSTCSQLGYMFVALGVGAYGAAIFHLFTHAFFKALLFLGSGSVIHAVSDEQDMRKMGGLRSLIPTTYWMMVIGTL
ALTGVGIPVTVIGTAGFFSKDAIIESAFAGHNSVAGLAFVLLVIAACFTSFYSWRLIFMTFHGEPRASHEVMHHVHESPP
VMLVPLFVLAAGALFAGIIFHNSFIGEGYAEFWKASLFTLPDNHILHEIHELPLWVELAPFIAMLIGFAVAWKFYIRSPE
LPRSVAANHRLLYAFLLNKWYFDELYDFLFVRPAKRLGHFLWKTGDGTVIDGLGPDGISARVVDVTNRVVKLQTGYLYHY
AFAMLIGVAALVTWMML

Sequences:

>Translated_657_residues
MYQAIVFLPLLGFLIVGLFGTSLGAKASEYITSGFLVISAVLSWVAFFSVGFGHGEVFTVPVLHWIQSGGLDASWALRID
TLTVVMLVVVNTVSALVHIYSIGYMHHDPNRPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPS
ANAAAIKAFVVNRVGDFGFALGIFGVFVLFGSVNLGTIFANAATFAPAEGAPQGAAVLTFLGHALDKQAAMTVVCLLLFM
GAMGKSAQVPLHTWLPDAMEGPTPVSALIHAATMVTAGVFMLARLSPLFELSHSALTVVTFIGAFTAFFAATVGLVQNDI
KRVIAYSTCSQLGYMFVALGVGAYGAAIFHLFTHAFFKALLFLGSGSVIHAVSDEQDMRKMGGLRSLIPTTYWMMVIGTL
ALTGVGIPVTVIGTAGFFSKDAIIESAFAGHNSVAGLAFVLLVIAACFTSFYSWRLIFMTFHGEPRASHEVMHHVHESPP
VMLVPLFVLAAGALFAGIIFHNSFIGEGYAEFWKASLFTLPDNHILHEIHELPLWVELAPFIAMLIGFAVAWKFYIRSPE
LPRSVAANHRLLYAFLLNKWYFDELYDFLFVRPAKRLGHFLWKTGDGTVIDGLGPDGISARVVDVTNRVVKLQTGYLYHY
AFAMLIGVAALVTWMML
>Mature_657_residues
MYQAIVFLPLLGFLIVGLFGTSLGAKASEYITSGFLVISAVLSWVAFFSVGFGHGEVFTVPVLHWIQSGGLDASWALRID
TLTVVMLVVVNTVSALVHIYSIGYMHHDPNRPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPS
ANAAAIKAFVVNRVGDFGFALGIFGVFVLFGSVNLGTIFANAATFAPAEGAPQGAAVLTFLGHALDKQAAMTVVCLLLFM
GAMGKSAQVPLHTWLPDAMEGPTPVSALIHAATMVTAGVFMLARLSPLFELSHSALTVVTFIGAFTAFFAATVGLVQNDI
KRVIAYSTCSQLGYMFVALGVGAYGAAIFHLFTHAFFKALLFLGSGSVIHAVSDEQDMRKMGGLRSLIPTTYWMMVIGTL
ALTGVGIPVTVIGTAGFFSKDAIIESAFAGHNSVAGLAFVLLVIAACFTSFYSWRLIFMTFHGEPRASHEVMHHVHESPP
VMLVPLFVLAAGALFAGIIFHNSFIGEGYAEFWKASLFTLPDNHILHEIHELPLWVELAPFIAMLIGFAVAWKFYIRSPE
LPRSVAANHRLLYAFLLNKWYFDELYDFLFVRPAKRLGHFLWKTGDGTVIDGLGPDGISARVVDVTNRVVKLQTGYLYHY
AFAMLIGVAALVTWMML

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=440, Percent_Identity=42.7272727272727, Blast_Score=324, Evalue=2e-88,
Organism=Escherichia coli, GI1788614, Length=605, Percent_Identity=41.6528925619835, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1788829, Length=447, Percent_Identity=31.5436241610738, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788831, Length=345, Percent_Identity=32.463768115942, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788827, Length=453, Percent_Identity=28.2560706401766, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788613, Length=423, Percent_Identity=25.7683215130024, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693160, Length=276, Percent_Identity=24.2753623188406, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI2367154, Length=223, Percent_Identity=27.8026905829596, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 71541; Mature: 71541

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQAIVFLPLLGFLIVGLFGTSLGAKASEYITSGFLVISAVLSWVAFFSVGFGHGEVFTV
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
PVLHWIQSGGLDASWALRIDTLTVVMLVVVNTVSALVHIYSIGYMHHDPNRPRFFAYLSL
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHH
FTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPSANAAAIKAFVVNRVGDFGFA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LGIFGVFVLFGSVNLGTIFANAATFAPAEGAPQGAAVLTFLGHALDKQAAMTVVCLLLFM
HHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAMGKSAQVPLHTWLPDAMEGPTPVSALIHAATMVTAGVFMLARLSPLFELSHSALTVVT
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGAFTAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYGAAIFHLFTHAFFKAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLGSGSVIHAVSDEQDMRKMGGLRSLIPTTYWMMVIGTLALTGVGIPVTVIGTAGFFSK
HHHCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHH
DAIIESAFAGHNSVAGLAFVLLVIAACFTSFYSWRLIFMTFHGEPRASHEVMHHVHESPP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHCCCC
VMLVPLFVLAAGALFAGIIFHNSFIGEGYAEFWKASLFTLPDNHILHEIHELPLWVELAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEECCCHHHHHHHHHCCHHHHHHH
FIAMLIGFAVAWKFYIRSPELPRSVAANHRLLYAFLLNKWYFDELYDFLFVRPAKRLGHF
HHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LWKTGDGTVIDGLGPDGISARVVDVTNRVVKLQTGYLYHYAFAMLIGVAALVTWMML
HEECCCCCEECCCCCCCCCEEEEEHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MYQAIVFLPLLGFLIVGLFGTSLGAKASEYITSGFLVISAVLSWVAFFSVGFGHGEVFTV
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
PVLHWIQSGGLDASWALRIDTLTVVMLVVVNTVSALVHIYSIGYMHHDPNRPRFFAYLSL
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHH
FTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPSANAAAIKAFVVNRVGDFGFA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LGIFGVFVLFGSVNLGTIFANAATFAPAEGAPQGAAVLTFLGHALDKQAAMTVVCLLLFM
HHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAMGKSAQVPLHTWLPDAMEGPTPVSALIHAATMVTAGVFMLARLSPLFELSHSALTVVT
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGAFTAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYGAAIFHLFTHAFFKAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLGSGSVIHAVSDEQDMRKMGGLRSLIPTTYWMMVIGTLALTGVGIPVTVIGTAGFFSK
HHHCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHH
DAIIESAFAGHNSVAGLAFVLLVIAACFTSFYSWRLIFMTFHGEPRASHEVMHHVHESPP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHCCCC
VMLVPLFVLAAGALFAGIIFHNSFIGEGYAEFWKASLFTLPDNHILHEIHELPLWVELAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEECCCHHHHHHHHHCCHHHHHHH
FIAMLIGFAVAWKFYIRSPELPRSVAANHRLLYAFLLNKWYFDELYDFLFVRPAKRLGHF
HHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LWKTGDGTVIDGLGPDGISARVVDVTNRVVKLQTGYLYHYAFAMLIGVAALVTWMML
HEECCCCCEECCCCCCCCCEEEEEHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]