Click here to switch to the map view.

The map label for this gene is lrhA [H]

Identifier: 13471311

GI number: 13471311

Start: 1048220

End: 1049119

Strand: Reverse

Name: lrhA [H]

Synonym: mll1248

Alternate gene names: 13471311

Gene position: 1049119-1048220 (Counterclockwise)

Preceding gene: 13471314

Following gene: 13471307

Centisome position: 14.91

GC content: 66.22

Gene sequence:

>900_bases
ATGAACGCCCCGCTCAATCATCCGCTGCCGCTGCTCGATCTCGACGTTTTGCGCACTTTCGTGGCGATTGCCGAGACCGG
CAGCTTCACCACTGCCGCCAATGCCGTCTTCCGCACGCCGTCCGCGGTCTCCATGCAGATCAAGAAGCTGGAGGACATTC
TCGGCCGCTCAGTGTTCGCGCGCGACGCCCGGTCGGTGTCGCTGACCACGGATGGCGAGATGCTGCTCGGCTATGCCCGC
CGGCTGCTGTCGATCAACCGTGAAGTGGTGTCGAAGTTCATCATTCCCGAGATTGTCGGGGTGGTGCGGCTCGGCTCGCC
GGATGATTATGGCGAGCGCGTGCTGCCGCATGTGCTGAAGCGTTTCGCGCAGTCGCATCCGTCGATCGCCGTCGACGTCA
CCATCGACCAGAGCAGCAATCTGCGCCGGCGCATGGACGACCGGGCGCTCGACATCACGCTTTTGACCAACTCCTACAAG
ACCAGCGCGCTCGGCGCCGAGGTGCTGCTCACCGAGCCGATCGTGTGGGCCGGCGCCAAGGGCGGCTGCGCGCATCTGCG
CGAACCGCTGCCGGTGTCATTGTGGGAAGAGGGGTGCGCCTGGCGTGCCGGCGCGCTCGAAGCCCTGGGGCGCGAGGGCC
GCAACTACCGCGTCGCCTATATGAGCGCGCACACGGCCGGCCAGCGTGCCGCGATCATGGCCGACCTGGCCGTCGCGCCG
CTGCCCCGATCATTCCTCGGCAACGACATGGTCGAGCTCTGCCCGAAGGACGGCATGCCCGATATCGGCACCTACAATCT
GGCCATGGTGGTGGCGCCGGACGCCAGCGCTCCGGTCAAAGCCGTCGCCGACCATATCCGCGCGACCTTCGAAGTGTTCC
GGGAAACCGGCAAGTTCTGA

Upstream 100 bases:

>100_bases
AGCAACCTCAACCGATGGAGTTGACTATCCTCCCAATCCGGTGTTCAATCAAACGAAATGGAATGATGCTTTGTATCAGA
AAATTTGAAGGTCGCTTCCG

Downstream 100 bases:

>100_bases
TCCGTCGCCGGATTGAAAGCGCTACTCCGCCGCCTCGGCGGAGGGCGCTTGAAACCTTGTTTTCCCGTCTTGCCTGACCG
GCGAGCGATTCTCGCCGAGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNAPLNHPLPLLDLDVLRTFVAIAETGSFTTAANAVFRTPSAVSMQIKKLEDILGRSVFARDARSVSLTTDGEMLLGYAR
RLLSINREVVSKFIIPEIVGVVRLGSPDDYGERVLPHVLKRFAQSHPSIAVDVTIDQSSNLRRRMDDRALDITLLTNSYK
TSALGAEVLLTEPIVWAGAKGGCAHLREPLPVSLWEEGCAWRAGALEALGREGRNYRVAYMSAHTAGQRAAIMADLAVAP
LPRSFLGNDMVELCPKDGMPDIGTYNLAMVVAPDASAPVKAVADHIRATFEVFRETGKF

Sequences:

>Translated_299_residues
MNAPLNHPLPLLDLDVLRTFVAIAETGSFTTAANAVFRTPSAVSMQIKKLEDILGRSVFARDARSVSLTTDGEMLLGYAR
RLLSINREVVSKFIIPEIVGVVRLGSPDDYGERVLPHVLKRFAQSHPSIAVDVTIDQSSNLRRRMDDRALDITLLTNSYK
TSALGAEVLLTEPIVWAGAKGGCAHLREPLPVSLWEEGCAWRAGALEALGREGRNYRVAYMSAHTAGQRAAIMADLAVAP
LPRSFLGNDMVELCPKDGMPDIGTYNLAMVVAPDASAPVKAVADHIRATFEVFRETGKF
>Mature_299_residues
MNAPLNHPLPLLDLDVLRTFVAIAETGSFTTAANAVFRTPSAVSMQIKKLEDILGRSVFARDARSVSLTTDGEMLLGYAR
RLLSINREVVSKFIIPEIVGVVRLGSPDDYGERVLPHVLKRFAQSHPSIAVDVTIDQSSNLRRRMDDRALDITLLTNSYK
TSALGAEVLLTEPIVWAGAKGGCAHLREPLPVSLWEEGCAWRAGALEALGREGRNYRVAYMSAHTAGQRAAIMADLAVAP
LPRSFLGNDMVELCPKDGMPDIGTYNLAMVVAPDASAPVKAVADHIRATFEVFRETGKF

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=277, Percent_Identity=32.8519855595668, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI48994962, Length=161, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786713, Length=74, Percent_Identity=48.6486486486487, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787806, Length=252, Percent_Identity=23.8095238095238, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790208, Length=132, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786448, Length=140, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32510; Mature: 32510

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLNHPLPLLDLDVLRTFVAIAETGSFTTAANAVFRTPSAVSMQIKKLEDILGRSVFA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RDARSVSLTTDGEMLLGYARRLLSINREVVSKFIIPEIVGVVRLGSPDDYGERVLPHVLK
CCCCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RFAQSHPSIAVDVTIDQSSNLRRRMDDRALDITLLTNSYKTSALGAEVLLTEPIVWAGAK
HHHHCCCCEEEEEEECCCCCHHHHHCCCEEEEEEEECCCCCHHCCCEEEEECCEEEECCC
GGCAHLREPLPVSLWEEGCAWRAGALEALGREGRNYRVAYMSAHTAGQRAAIMADLAVAP
CCHHHCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHCC
LPRSFLGNDMVELCPKDGMPDIGTYNLAMVVAPDASAPVKAVADHIRATFEVFRETGKF
CCHHHHCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAPLNHPLPLLDLDVLRTFVAIAETGSFTTAANAVFRTPSAVSMQIKKLEDILGRSVFA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RDARSVSLTTDGEMLLGYARRLLSINREVVSKFIIPEIVGVVRLGSPDDYGERVLPHVLK
CCCCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RFAQSHPSIAVDVTIDQSSNLRRRMDDRALDITLLTNSYKTSALGAEVLLTEPIVWAGAK
HHHHCCCCEEEEEEECCCCCHHHHHCCCEEEEEEEECCCCCHHCCCEEEEECCEEEECCC
GGCAHLREPLPVSLWEEGCAWRAGALEALGREGRNYRVAYMSAHTAGQRAAIMADLAVAP
CCHHHCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHCC
LPRSFLGNDMVELCPKDGMPDIGTYNLAMVVAPDASAPVKAVADHIRATFEVFRETGKF
CCHHHHCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]