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The map label for this gene is putA [H]

Identifier: 13471243

GI number: 13471243

Start: 970578

End: 974231

Strand: Reverse

Name: putA [H]

Synonym: mll1160

Alternate gene names: 13471243

Gene position: 974231-970578 (Counterclockwise)

Preceding gene: 13471245

Following gene: 13471237

Centisome position: 13.85

GC content: 67.49

Gene sequence:

>3654_bases
GTGACCGCCGGCCCGCTCCCTGACGCTCGCTCCACGGGACCCGCCATGCCGCTCGACACCATCCGCCAGCAGATCCGCGC
CAACTATCTGCCCGACGAAGATGAGGCCGTGAAACGATTGGCCGAGGCGACAGGGCTTTCGGCTGCGGATCGCGACGCGA
TCTCGGCGCGAGCCGCCGATCTGGTGCGGGCGGTGCGCGGCTCGTCCGATCCCCGGCTGATGGAGGTTTTCCTCTCGGCC
TACGGCCTTTCCACCAAGGAGGGCGTGGCGCTGATGTGCCTGGCCGAGGCGCTGCTGCGCGTGCCCGACACCGAGACGAT
GGACGATCTCATCGCCGACAAGATCGCGCCGCATGACTGGTCGGCGCATTCGGGTGGTTCGAGCTCGATCTTCGTCAACG
CCTCGACCTGGGCGCTGATGCTGACCGGCCGCGTGCTGGACGAGGGCGAGGGCGGTATCGAAGGCACGTTGCGCTCCATG
GTGCGCAGGCTGGGCGAGCCGGTCATCCGCAAGGCGGTGGCCGCCGCCATGCGCGAGATGGGCGAACAGTTCGTGCTCGG
CCGCACCATTGCAGAAGCCGTCAAGCGCGGCCGGCCGATGACACAGAAGGGCTACCTCTATTCCTTCGACATGCTGGGCG
AGGCGGCCCGCACCGAGGCCGATGCACTGCGCTACCACAAGGCCTATGCCGACGCGATTTCGTCGCTCGATGCCGGCTCC
AATGGTCCCGACATCAGGCAAAACCACGGCATCTCGGTCAAGCTTTCGGCGCTGCATCCGCGCTACGAAGTGGCGCAGAA
GGAAGAGATGCTGCCTGTCATGGCCGAGCGGCTGCTGTCGCTGGCGCTTGCGGCCAGACATTCGCGCATGGGTCTCAACA
TCGACGCCGAGGAGGCCGATCGCTTGGATCTGTCGCTCGACGTCATCGAGCGCGTGCTGGCCGAGCCGGAACTCGCCGGC
TGGAACGGCTTTGGCGTGGTCGTGCAAGCGTATGGGCCGCGCGCGGCCTTCGTCATCGACTGGCTCTATGCTCTGGCCAG
GAAATACGACCGCACCATCATGGTGCGGCTGGTCAAGGGCGCCTATTGGGACACCGAGATCAAGCGGGCGCAGACGCTCG
GACTTGCCGGCTATCCCGTCTTCACCCGCAAGGCCAACACCGACGTTTCCTACATGGCTTGCGCGAAGAAACTGCTTGGC
ATGACCGACCGCATCTATCCGCAATTCGCCACCCACAACGCCCACACCGTCGCGGCCATCCTGTCGATGGCCACGAACCG
CGATTCCTTCGAATTCCAGCGCCTGCATGGCATGGGCGAGGCGTTGCACGAGACGGTGCGCCAGGCCGAAGGCACGCGCT
GCCGCATCTATGCGCCAGTCGGCGCGCATTCGGACCTGCTGGCCTATCTGGTCCGCCGGCTGCTCGAGAACGGCGCCAAC
TCCTCCTTCGTGCACCAACTGACCGACGAGGATGTCGAGCCGGAAGACATCGCGCGCGATCCGCTCGAAACGGTCGAAAG
CCAAGGCCCTGCCGCCAATCCGGCGATTGCCAGGCCGTCGCAGATTTTTGGCGCAGGCCGCCGCAATTCCAGAGGTTTCG
ACATCACCGACACGGTGACGCTGGCGGCCATCGACAAGGCCAGGGCGGCGTTCGCCGGGCCGGACCGCTGGCATGCCAAG
CCGATCACGCGGGCCGCCGGCTATGGCAAGCCGCACCCGGTCGTCAATCCGGCCAAGCCCGATGAAGTGGTCGGGACGGT
TCACGAGGCCGCCGCCAAGCAGGTCGCGATCGCCGTGCGCATCGCGGTGGAGGCGCAGCCGGCCTGGGCGAAGCGTCCCG
TTGGCGAACGCGCCGCCATCCTCAACCGCGCCGCCGATCTCTATGAAGCCAATGCGGTCGAGTTCTTCGCGCTCGCCACC
CGCGAGGCCGGCAAATCGCTGGCCGATGGTGTGGCGGAAGTGCGCGAGGCCGTCGACTTCCTGCGCTACTACGCCGCCGA
GGCGGCAAACGCCGAGACGGGCACGCAGGCGCGCGGCGCGATCGTCTGTATTTCGCCGTGGAATTTCCCGTTGGCGATCT
TCACCGGCCAGATCGCGGCAGCACTCGTTACCGGCAATTCGGTCATCGCCAAGCCGGCCGAACAGACACCGCTGATTGCC
TTCCGCGCCGTCGAGTTGCTGCGCGAGGCCGGCGTGCCGGAAGACATCATCCAACTGCTGCCCGGCGACGGCCCATCGGT
CGGCGGACCGCTGACCGCCGACCCACGCATTGCCGGCGTCTGCTTCACCGGCTCGACCGAAGTCGCCAAGCTGATCGAGA
AACAGCTGGCCGAGACCGCGGCACCCGACGCCATGCTGATCGCCGAGACCGGTGGTTTGAACGCCATGATCGTCGATTCC
ACCGCGCTGCCCGAGCAGGCGGTGCGCGATATACTGGCCTCTGCCTTCCAGAGTGCCGGCCAGCGCTGCTCGGCGCTGCG
CGTGCTCTACGTGCAGAAGGACGTCGAGAAGAAGATGCTGGACATGCTGAAGGGCGCCATGGAGGCGCTCAACATCGGGG
ATCCCTGGCGGATTTCGACTGATGTCGGTCCGGTCATCGATGATGAGGCGCAGGCCTCTATCCGTGACTATTGCACCAGG
AAAGGTCTCGAGGGGCGGCTGATCGCCAAGCTCGAGGCGCCGAAGGACGGGCGCTTCGTCGCGCCGCATGTCTTCCGGGT
CAAGGGCATCGAGGAGATGGAGCGCGAAGTGTTCGGGCCGGTGCTGCACGTCGCCAGCTTCGACGCCGATGAGATCGATG
CTGTCATCGCTGCCATCAACCGCAAGGGCTATGGCCTGACCTTCGGCCTGCACACCCGCATCGAAGGTCGCGTCCAGCAT
TTCGTCGACGGCATCCATGCTGGCAACATCTACGTCAACCGCAACCAGATCGGCGCCGTGGTCGGTTCCCAGCCCTTTGG
CGGCGAGGGGCTTTCCGGCACCGGGCCGAAGGCTGGCGGCCCGCATTATCTGCGCCGCTTCCGCAAGGGGCCGGAAGCCG
GCACAGAGGTTGGCGAGGGCCACAAGGTGACGGCGACCGAACTGGCCGACAATCTGCCCGATCCGGCCCTCGGCGGCTGG
TCGACGCGCCCGGACCGGATCGCCATCCTGAGGAAGCATCTGCGCGGCAAGGGCGCTGCCGCCATCGGCGCTGCCGCTGC
AATCGATTTCGGCCAGGTCGACCTGCCCGGCCCGACCGGCGAGGCCAATACGCTGTCGCTGTCGCCGCGCGGGCGGGTGT
TGTGCCTGGGGCCGGATGCCGAGACGCTGCTCGCCCAGACCATCCAGGCGCTCGCCGCCGGCAATGCAGTGCTGGCCGTG
GCCCCTGGGGCGCCGGCCGCCTTGTCGGCGCTGACCGGCAAGGGCTTGCCGCTCGCGGCGATAGATGGCCGCCCCGATCC
GGTCGAGGCGCGCGCGCTGCGCGTCGATGTCGTCGCTTTCTCGGGTACGCCGGAGGCCGCGCGCATCGTGCGCCAGGTGA
TCGCCGACAGGACCGGCCCGATCGTGCCGCTGGTCAGCGAGGTGCTCAATCCGGCCGCCTATGCGCATGAGCGCGCGGTC
TGTGTCGACACCACGGCCGCGGGCGGCAATGCCAGCCTGCTTGCCGCGGCCTAG

Upstream 100 bases:

>100_bases
TCAGAGGGGTTGACATAACGATAGATCGATCGATCTGTCTTGTCGATTTCTTTGGACCGACTGAAATCCGCGCCTGTGCT
AGCTTGCGCCATTCGGTCCG

Downstream 100 bases:

>100_bases
TTCAGCCTATTCTCAGGCGCCCTCGACGACCGAAAAGCCCTCGAATTGTGGGTGGCCGAGATAGTGGACCTTCGTCGTGC
CGACATTCCTGTGCGCGGCG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1217; Mature: 1216

Protein sequence:

>1217_residues
MTAGPLPDARSTGPAMPLDTIRQQIRANYLPDEDEAVKRLAEATGLSAADRDAISARAADLVRAVRGSSDPRLMEVFLSA
YGLSTKEGVALMCLAEALLRVPDTETMDDLIADKIAPHDWSAHSGGSSSIFVNASTWALMLTGRVLDEGEGGIEGTLRSM
VRRLGEPVIRKAVAAAMREMGEQFVLGRTIAEAVKRGRPMTQKGYLYSFDMLGEAARTEADALRYHKAYADAISSLDAGS
NGPDIRQNHGISVKLSALHPRYEVAQKEEMLPVMAERLLSLALAARHSRMGLNIDAEEADRLDLSLDVIERVLAEPELAG
WNGFGVVVQAYGPRAAFVIDWLYALARKYDRTIMVRLVKGAYWDTEIKRAQTLGLAGYPVFTRKANTDVSYMACAKKLLG
MTDRIYPQFATHNAHTVAAILSMATNRDSFEFQRLHGMGEALHETVRQAEGTRCRIYAPVGAHSDLLAYLVRRLLENGAN
SSFVHQLTDEDVEPEDIARDPLETVESQGPAANPAIARPSQIFGAGRRNSRGFDITDTVTLAAIDKARAAFAGPDRWHAK
PITRAAGYGKPHPVVNPAKPDEVVGTVHEAAAKQVAIAVRIAVEAQPAWAKRPVGERAAILNRAADLYEANAVEFFALAT
REAGKSLADGVAEVREAVDFLRYYAAEAANAETGTQARGAIVCISPWNFPLAIFTGQIAAALVTGNSVIAKPAEQTPLIA
FRAVELLREAGVPEDIIQLLPGDGPSVGGPLTADPRIAGVCFTGSTEVAKLIEKQLAETAAPDAMLIAETGGLNAMIVDS
TALPEQAVRDILASAFQSAGQRCSALRVLYVQKDVEKKMLDMLKGAMEALNIGDPWRISTDVGPVIDDEAQASIRDYCTR
KGLEGRLIAKLEAPKDGRFVAPHVFRVKGIEEMEREVFGPVLHVASFDADEIDAVIAAINRKGYGLTFGLHTRIEGRVQH
FVDGIHAGNIYVNRNQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRKGPEAGTEVGEGHKVTATELADNLPDPALGGW
STRPDRIAILRKHLRGKGAAAIGAAAAIDFGQVDLPGPTGEANTLSLSPRGRVLCLGPDAETLLAQTIQALAAGNAVLAV
APGAPAALSALTGKGLPLAAIDGRPDPVEARALRVDVVAFSGTPEAARIVRQVIADRTGPIVPLVSEVLNPAAYAHERAV
CVDTTAAGGNASLLAAA

Sequences:

>Translated_1217_residues
MTAGPLPDARSTGPAMPLDTIRQQIRANYLPDEDEAVKRLAEATGLSAADRDAISARAADLVRAVRGSSDPRLMEVFLSA
YGLSTKEGVALMCLAEALLRVPDTETMDDLIADKIAPHDWSAHSGGSSSIFVNASTWALMLTGRVLDEGEGGIEGTLRSM
VRRLGEPVIRKAVAAAMREMGEQFVLGRTIAEAVKRGRPMTQKGYLYSFDMLGEAARTEADALRYHKAYADAISSLDAGS
NGPDIRQNHGISVKLSALHPRYEVAQKEEMLPVMAERLLSLALAARHSRMGLNIDAEEADRLDLSLDVIERVLAEPELAG
WNGFGVVVQAYGPRAAFVIDWLYALARKYDRTIMVRLVKGAYWDTEIKRAQTLGLAGYPVFTRKANTDVSYMACAKKLLG
MTDRIYPQFATHNAHTVAAILSMATNRDSFEFQRLHGMGEALHETVRQAEGTRCRIYAPVGAHSDLLAYLVRRLLENGAN
SSFVHQLTDEDVEPEDIARDPLETVESQGPAANPAIARPSQIFGAGRRNSRGFDITDTVTLAAIDKARAAFAGPDRWHAK
PITRAAGYGKPHPVVNPAKPDEVVGTVHEAAAKQVAIAVRIAVEAQPAWAKRPVGERAAILNRAADLYEANAVEFFALAT
REAGKSLADGVAEVREAVDFLRYYAAEAANAETGTQARGAIVCISPWNFPLAIFTGQIAAALVTGNSVIAKPAEQTPLIA
FRAVELLREAGVPEDIIQLLPGDGPSVGGPLTADPRIAGVCFTGSTEVAKLIEKQLAETAAPDAMLIAETGGLNAMIVDS
TALPEQAVRDILASAFQSAGQRCSALRVLYVQKDVEKKMLDMLKGAMEALNIGDPWRISTDVGPVIDDEAQASIRDYCTR
KGLEGRLIAKLEAPKDGRFVAPHVFRVKGIEEMEREVFGPVLHVASFDADEIDAVIAAINRKGYGLTFGLHTRIEGRVQH
FVDGIHAGNIYVNRNQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRKGPEAGTEVGEGHKVTATELADNLPDPALGGW
STRPDRIAILRKHLRGKGAAAIGAAAAIDFGQVDLPGPTGEANTLSLSPRGRVLCLGPDAETLLAQTIQALAAGNAVLAV
APGAPAALSALTGKGLPLAAIDGRPDPVEARALRVDVVAFSGTPEAARIVRQVIADRTGPIVPLVSEVLNPAAYAHERAV
CVDTTAAGGNASLLAAA
>Mature_1216_residues
TAGPLPDARSTGPAMPLDTIRQQIRANYLPDEDEAVKRLAEATGLSAADRDAISARAADLVRAVRGSSDPRLMEVFLSAY
GLSTKEGVALMCLAEALLRVPDTETMDDLIADKIAPHDWSAHSGGSSSIFVNASTWALMLTGRVLDEGEGGIEGTLRSMV
RRLGEPVIRKAVAAAMREMGEQFVLGRTIAEAVKRGRPMTQKGYLYSFDMLGEAARTEADALRYHKAYADAISSLDAGSN
GPDIRQNHGISVKLSALHPRYEVAQKEEMLPVMAERLLSLALAARHSRMGLNIDAEEADRLDLSLDVIERVLAEPELAGW
NGFGVVVQAYGPRAAFVIDWLYALARKYDRTIMVRLVKGAYWDTEIKRAQTLGLAGYPVFTRKANTDVSYMACAKKLLGM
TDRIYPQFATHNAHTVAAILSMATNRDSFEFQRLHGMGEALHETVRQAEGTRCRIYAPVGAHSDLLAYLVRRLLENGANS
SFVHQLTDEDVEPEDIARDPLETVESQGPAANPAIARPSQIFGAGRRNSRGFDITDTVTLAAIDKARAAFAGPDRWHAKP
ITRAAGYGKPHPVVNPAKPDEVVGTVHEAAAKQVAIAVRIAVEAQPAWAKRPVGERAAILNRAADLYEANAVEFFALATR
EAGKSLADGVAEVREAVDFLRYYAAEAANAETGTQARGAIVCISPWNFPLAIFTGQIAAALVTGNSVIAKPAEQTPLIAF
RAVELLREAGVPEDIIQLLPGDGPSVGGPLTADPRIAGVCFTGSTEVAKLIEKQLAETAAPDAMLIAETGGLNAMIVDST
ALPEQAVRDILASAFQSAGQRCSALRVLYVQKDVEKKMLDMLKGAMEALNIGDPWRISTDVGPVIDDEAQASIRDYCTRK
GLEGRLIAKLEAPKDGRFVAPHVFRVKGIEEMEREVFGPVLHVASFDADEIDAVIAAINRKGYGLTFGLHTRIEGRVQHF
VDGIHAGNIYVNRNQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRKGPEAGTEVGEGHKVTATELADNLPDPALGGWS
TRPDRIAILRKHLRGKGAAAIGAAAAIDFGQVDLPGPTGEANTLSLSPRGRVLCLGPDAETLLAQTIQALAAGNAVLAVA
PGAPAALSALTGKGLPLAAIDGRPDPVEARALRVDVVAFSGTPEAARIVRQVIADRTGPIVPLVSEVLNPAAYAHERAVC
VDTTAAGGNASLLAAA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777730, Length=453, Percent_Identity=32.6710816777042, Blast_Score=188, Evalue=3e-47,
Organism=Homo sapiens, GI25777736, Length=453, Percent_Identity=31.5673289183223, Blast_Score=187, Evalue=5e-47,
Organism=Homo sapiens, GI25777734, Length=453, Percent_Identity=31.5673289183223, Blast_Score=187, Evalue=5e-47,
Organism=Homo sapiens, GI238859541, Length=453, Percent_Identity=31.5673289183223, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI153266822, Length=469, Percent_Identity=29.4243070362473, Blast_Score=185, Evalue=3e-46,
Organism=Homo sapiens, GI25777732, Length=467, Percent_Identity=30.6209850107066, Blast_Score=183, Evalue=8e-46,
Organism=Homo sapiens, GI21361176, Length=456, Percent_Identity=32.0175438596491, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI12007648, Length=451, Percent_Identity=29.490022172949, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI25777724, Length=455, Percent_Identity=30.3296703296703, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI21614513, Length=415, Percent_Identity=29.6385542168675, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI238814322, Length=415, Percent_Identity=28.9156626506024, Blast_Score=167, Evalue=7e-41,
Organism=Homo sapiens, GI25777728, Length=405, Percent_Identity=30.3703703703704, Blast_Score=160, Evalue=7e-39,
Organism=Homo sapiens, GI115387104, Length=440, Percent_Identity=28.8636363636364, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI25952152, Length=445, Percent_Identity=27.4157303370787, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI4507229, Length=421, Percent_Identity=27.5534441805226, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI188035924, Length=453, Percent_Identity=27.5938189845475, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI310128103, Length=453, Percent_Identity=27.5938189845475, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI310128093, Length=443, Percent_Identity=27.5395033860045, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI11095441, Length=422, Percent_Identity=27.4881516587678, Blast_Score=127, Evalue=6e-29,
Organism=Homo sapiens, GI25777721, Length=434, Percent_Identity=26.4976958525346, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI25777726, Length=455, Percent_Identity=26.5934065934066, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI310128091, Length=392, Percent_Identity=28.0612244897959, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI301500698, Length=437, Percent_Identity=24.9427917620137, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI71773324, Length=391, Percent_Identity=25.0639386189258, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI4502043, Length=325, Percent_Identity=26.4615384615385, Blast_Score=101, Evalue=6e-21,
Organism=Homo sapiens, GI238814371, Length=325, Percent_Identity=26.4615384615385, Blast_Score=101, Evalue=6e-21,
Organism=Homo sapiens, GI310128089, Length=330, Percent_Identity=27.5757575757576, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI73695881, Length=325, Percent_Identity=25.2307692307692, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI73695879, Length=325, Percent_Identity=25.2307692307692, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI310128095, Length=308, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI206597441, Length=326, Percent_Identity=25.1533742331288, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI206597439, Length=326, Percent_Identity=25.1533742331288, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI22907049, Length=326, Percent_Identity=25.1533742331288, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128087, Length=271, Percent_Identity=28.4132841328413, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI310128097, Length=255, Percent_Identity=28.2352941176471, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI4557303, Length=327, Percent_Identity=23.8532110091743, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI73466520, Length=327, Percent_Identity=23.8532110091743, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI310128101, Length=216, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=7e-12,
Organism=Homo sapiens, GI310128099, Length=216, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=7e-12,
Organism=Escherichia coli, GI1787250, Length=1251, Percent_Identity=47.5619504396483, Blast_Score=1009, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=461, Percent_Identity=32.5379609544469, Blast_Score=180, Evalue=5e-46,
Organism=Escherichia coli, GI1787684, Length=452, Percent_Identity=30.9734513274336, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1787715, Length=451, Percent_Identity=31.7073170731707, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI87081896, Length=474, Percent_Identity=30.5907172995781, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1786504, Length=457, Percent_Identity=28.6652078774617, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1788042, Length=439, Percent_Identity=30.0683371298405, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI1787558, Length=423, Percent_Identity=31.9148936170213, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI87082295, Length=450, Percent_Identity=27.7777777777778, Blast_Score=136, Evalue=9e-33,
Organism=Escherichia coli, GI87081926, Length=438, Percent_Identity=23.7442922374429, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1787653, Length=369, Percent_Identity=24.9322493224932, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=31.4533622559653, Blast_Score=192, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25144435, Length=472, Percent_Identity=31.1440677966102, Blast_Score=177, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17562198, Length=452, Percent_Identity=31.6371681415929, Blast_Score=174, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI133930964, Length=553, Percent_Identity=27.4864376130199, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI25143876, Length=438, Percent_Identity=29.9086757990868, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25143874, Length=438, Percent_Identity=29.9086757990868, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI115532534, Length=378, Percent_Identity=32.2751322751323, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI32564736, Length=422, Percent_Identity=31.2796208530806, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115534176, Length=459, Percent_Identity=30.718954248366, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564151, Length=426, Percent_Identity=29.5774647887324, Blast_Score=147, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17551164, Length=453, Percent_Identity=28.0353200883002, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534119, Length=460, Percent_Identity=28.0434782608696, Blast_Score=132, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=442, Percent_Identity=25.5656108597285, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=299, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=422, Percent_Identity=25.5924170616114, Blast_Score=120, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=399, Percent_Identity=25.31328320802, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17564084, Length=364, Percent_Identity=25, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25146391, Length=322, Percent_Identity=24.8447204968944, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=322, Percent_Identity=24.8447204968944, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=322, Percent_Identity=24.8447204968944, Blast_Score=84, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=449, Percent_Identity=34.2984409799555, Blast_Score=194, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6321826, Length=477, Percent_Identity=30.8176100628931, Blast_Score=171, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6325196, Length=456, Percent_Identity=30.9210526315789, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=448, Percent_Identity=31.4732142857143, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=458, Percent_Identity=29.2576419213974, Blast_Score=161, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6323821, Length=459, Percent_Identity=29.8474945533769, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6319478, Length=445, Percent_Identity=28.0898876404494, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321828, Length=494, Percent_Identity=25.7085020242915, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=327, Percent_Identity=25.9938837920489, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668425, Length=466, Percent_Identity=30.4721030042918, Blast_Score=190, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24668417, Length=466, Percent_Identity=30.4721030042918, Blast_Score=190, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24668413, Length=466, Percent_Identity=30.4721030042918, Blast_Score=190, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24650465, Length=455, Percent_Identity=30.1098901098901, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI20129399, Length=468, Percent_Identity=30.7692307692308, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24585660, Length=451, Percent_Identity=29.7117516629712, Blast_Score=173, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28571798, Length=474, Percent_Identity=29.1139240506329, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571796, Length=474, Percent_Identity=29.1139240506329, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571794, Length=474, Percent_Identity=29.1139240506329, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571802, Length=474, Percent_Identity=29.1139240506329, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571800, Length=474, Percent_Identity=29.1139240506329, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571806, Length=474, Percent_Identity=29.1139240506329, Blast_Score=157, Evalue=6e-38,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=30.0884955752212, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=30.0884955752212, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=30.0884955752212, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=30.0884955752212, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=30.0884955752212, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24666674, Length=457, Percent_Identity=28.0087527352298, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574525, Length=458, Percent_Identity=24.6724890829694, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24638878, Length=415, Percent_Identity=26.9879518072289, Blast_Score=118, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638876, Length=415, Percent_Identity=26.9879518072289, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281360301, Length=329, Percent_Identity=27.355623100304, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360299, Length=329, Percent_Identity=27.355623100304, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360297, Length=329, Percent_Identity=27.355623100304, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360295, Length=329, Percent_Identity=27.355623100304, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586250, Length=329, Percent_Identity=27.355623100304, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45552499, Length=329, Percent_Identity=26.7477203647416, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281360303, Length=329, Percent_Identity=26.7477203647416, Blast_Score=90, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 129532; Mature: 129401

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGPLPDARSTGPAMPLDTIRQQIRANYLPDEDEAVKRLAEATGLSAADRDAISARAAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LVRAVRGSSDPRLMEVFLSAYGLSTKEGVALMCLAEALLRVPDTETMDDLIADKIAPHDW
HHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
SAHSGGSSSIFVNASTWALMLTGRVLDEGEGGIEGTLRSMVRRLGEPVIRKAVAAAMREM
CCCCCCCCEEEEECCCEEEEEECHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GEQFVLGRTIAEAVKRGRPMTQKGYLYSFDMLGEAARTEADALRYHKAYADAISSLDAGS
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NGPDIRQNHGISVKLSALHPRYEVAQKEEMLPVMAERLLSLALAARHSRMGLNIDAEEAD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHC
RLDLSLDVIERVLAEPELAGWNGFGVVVQAYGPRAAFVIDWLYALARKYDRTIMVRLVKG
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHC
AYWDTEIKRAQTLGLAGYPVFTRKANTDVSYMACAKKLLGMTDRIYPQFATHNAHTVAAI
CCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHH
LSMATNRDSFEFQRLHGMGEALHETVRQAEGTRCRIYAPVGAHSDLLAYLVRRLLENGAN
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
SSFVHQLTDEDVEPEDIARDPLETVESQGPAANPAIARPSQIFGAGRRNSRGFDITDTVT
CHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHEE
LAAIDKARAAFAGPDRWHAKPITRAAGYGKPHPVVNPAKPDEVVGTVHEAAAKQVAIAVR
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEE
IAVEAQPAWAKRPVGERAAILNRAADLYEANAVEFFALATREAGKSLADGVAEVREAVDF
EEEECCCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRYYAAEAANAETGTQARGAIVCISPWNFPLAIFTGQIAAALVTGNSVIAKPAEQTPLIA
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHEEEEECCCEEECCCCCCCHHH
FRAVELLREAGVPEDIIQLLPGDGPSVGGPLTADPRIAGVCFTGSTEVAKLIEKQLAETA
HHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
APDAMLIAETGGLNAMIVDSTALPEQAVRDILASAFQSAGQRCSALRVLYVQKDVEKKML
CCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLKGAMEALNIGDPWRISTDVGPVIDDEAQASIRDYCTRKGLEGRLIAKLEAPKDGRFV
HHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEE
APHVFRVKGIEEMEREVFGPVLHVASFDADEIDAVIAAINRKGYGLTFGLHTRIEGRVQH
CCHHHEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
FVDGIHAGNIYVNRNQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRKGPEAGTEVGEG
HHCCEEECCEEEECCHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
HKVTATELADNLPDPALGGWSTRPDRIAILRKHLRGKGAAAIGAAAAIDFGQVDLPGPTG
CEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCCCC
EANTLSLSPRGRVLCLGPDAETLLAQTIQALAAGNAVLAVAPGAPAALSALTGKGLPLAA
CCCEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCEEEE
IDGRPDPVEARALRVDVVAFSGTPEAARIVRQVIADRTGPIVPLVSEVLNPAAYAHERAV
ECCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHCCEE
CVDTTAAGGNASLLAAA
EEEECCCCCCCEEEEEC
>Mature Secondary Structure 
TAGPLPDARSTGPAMPLDTIRQQIRANYLPDEDEAVKRLAEATGLSAADRDAISARAAD
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LVRAVRGSSDPRLMEVFLSAYGLSTKEGVALMCLAEALLRVPDTETMDDLIADKIAPHDW
HHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
SAHSGGSSSIFVNASTWALMLTGRVLDEGEGGIEGTLRSMVRRLGEPVIRKAVAAAMREM
CCCCCCCCEEEEECCCEEEEEECHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GEQFVLGRTIAEAVKRGRPMTQKGYLYSFDMLGEAARTEADALRYHKAYADAISSLDAGS
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NGPDIRQNHGISVKLSALHPRYEVAQKEEMLPVMAERLLSLALAARHSRMGLNIDAEEAD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHC
RLDLSLDVIERVLAEPELAGWNGFGVVVQAYGPRAAFVIDWLYALARKYDRTIMVRLVKG
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHC
AYWDTEIKRAQTLGLAGYPVFTRKANTDVSYMACAKKLLGMTDRIYPQFATHNAHTVAAI
CCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHH
LSMATNRDSFEFQRLHGMGEALHETVRQAEGTRCRIYAPVGAHSDLLAYLVRRLLENGAN
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
SSFVHQLTDEDVEPEDIARDPLETVESQGPAANPAIARPSQIFGAGRRNSRGFDITDTVT
CHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHEE
LAAIDKARAAFAGPDRWHAKPITRAAGYGKPHPVVNPAKPDEVVGTVHEAAAKQVAIAVR
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEE
IAVEAQPAWAKRPVGERAAILNRAADLYEANAVEFFALATREAGKSLADGVAEVREAVDF
EEEECCCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRYYAAEAANAETGTQARGAIVCISPWNFPLAIFTGQIAAALVTGNSVIAKPAEQTPLIA
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHEEEEECCCEEECCCCCCCHHH
FRAVELLREAGVPEDIIQLLPGDGPSVGGPLTADPRIAGVCFTGSTEVAKLIEKQLAETA
HHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
APDAMLIAETGGLNAMIVDSTALPEQAVRDILASAFQSAGQRCSALRVLYVQKDVEKKML
CCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLKGAMEALNIGDPWRISTDVGPVIDDEAQASIRDYCTRKGLEGRLIAKLEAPKDGRFV
HHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEE
APHVFRVKGIEEMEREVFGPVLHVASFDADEIDAVIAAINRKGYGLTFGLHTRIEGRVQH
CCHHHEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
FVDGIHAGNIYVNRNQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRKGPEAGTEVGEG
HHCCEEECCEEEECCHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
HKVTATELADNLPDPALGGWSTRPDRIAILRKHLRGKGAAAIGAAAAIDFGQVDLPGPTG
CEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCCCC
EANTLSLSPRGRVLCLGPDAETLLAQTIQALAAGNAVLAVAPGAPAALSALTGKGLPLAA
CCCEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCEEEE
IDGRPDPVEARALRVDVVAFSGTPEAARIVRQVIADRTGPIVPLVSEVLNPAAYAHERAV
ECCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHCCEE
CVDTTAAGGNASLLAAA
EEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]