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The map label for this gene is cutC

Identifier: 13471212

GI number: 13471212

Start: 939715

End: 940491

Strand: Direct

Name: cutC

Synonym: mlr1122

Alternate gene names: 13471212

Gene position: 939715-940491 (Clockwise)

Preceding gene: 13471210

Following gene: 13471213

Centisome position: 13.36

GC content: 67.44

Gene sequence:

>777_bases
ATGGACTGGATCGACCCCTTGACCACGGAAACCCGCCTGCCCCTGATCGAAATCTGTGTAGAAGGCATCGATGGCCTGCT
CGCCGCGCAGGCTGCCGGCGCCGACCGGGTCGAACTGTGCGCCAGCCTCGTCGAGGGCGGCATCACACCGAGCCTCGGCA
CGGTGCGCGCCGCTCTCGACCAGGCGACCGTGCCGTTTCACGTCATGGTGCGGCCGCGCGGCGGCGATTTTCTCTACAGC
GAGACCGAATACCGCTCGATGCTCGCCGATGTCGCGGCACTGCGCGATCTCGGCGTGCCCGGCGTGGTGTTTGGCTGCCT
GAACGCCGACGGCACCATCGACGAGAAGCGCATGGGCGAACTGACGGAGGCCGCCGGCCCCCTGAACGTCACTTGCCATC
GCGCCTTCGACATGACACGCGACCCGGCCGAGGCGCTGGAGGCGCTGATCCGCTGCAAGGTCGGCCGCGTGCTGACCAGC
GGCCAACGCGACAGCGCGATCGAAGGCCTGCCCTTGCTGGCCGATCTGGTGCGGCAGGCCGGCGACCGCATCATCATCCT
CGGTTGCGGCGGGCTTGATCTCGCAAACATCGCCGAGGTGCGCCGAAAGACCGGGCTGGCCGAAATGCATTTTGCCGCGC
TGAAGGACGTGCCAAGCACCATGCGCTACCGCAATCCCAAGGTCGGCATGGGCGGCTCCGATCTCGACCGCGAGTACCGC
AACACATTAACCGACACACCGCTGGTGGCGGCGACGATCGCGGCGGCCAAGGCATGA

Upstream 100 bases:

>100_bases
ATAAGACTGTCAAGCTGGGAAATGTCGCCTGGTCCAAACGGCGGTGCGCCGTTCACGCTTTCGCGCTAGCCGCCCGGGTG
CTAGGGCTTTGCGCAACATC

Downstream 100 bases:

>100_bases
CCTCGCCGATAGACCGTATAGCGCCAGGCGACGAAGCGGACATATTGGCGCTCAACAACGAGCATGCCGCCGAACTGTCC
TGGCTCGAAGCCGAACGGCT

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MDWIDPLTTETRLPLIEICVEGIDGLLAAQAAGADRVELCASLVEGGITPSLGTVRAALDQATVPFHVMVRPRGGDFLYS
ETEYRSMLADVAALRDLGVPGVVFGCLNADGTIDEKRMGELTEAAGPLNVTCHRAFDMTRDPAEALEALIRCKVGRVLTS
GQRDSAIEGLPLLADLVRQAGDRIIILGCGGLDLANIAEVRRKTGLAEMHFAALKDVPSTMRYRNPKVGMGGSDLDREYR
NTLTDTPLVAATIAAAKA

Sequences:

>Translated_258_residues
MDWIDPLTTETRLPLIEICVEGIDGLLAAQAAGADRVELCASLVEGGITPSLGTVRAALDQATVPFHVMVRPRGGDFLYS
ETEYRSMLADVAALRDLGVPGVVFGCLNADGTIDEKRMGELTEAAGPLNVTCHRAFDMTRDPAEALEALIRCKVGRVLTS
GQRDSAIEGLPLLADLVRQAGDRIIILGCGGLDLANIAEVRRKTGLAEMHFAALKDVPSTMRYRNPKVGMGGSDLDREYR
NTLTDTPLVAATIAAAKA
>Mature_258_residues
MDWIDPLTTETRLPLIEICVEGIDGLLAAQAAGADRVELCASLVEGGITPSLGTVRAALDQATVPFHVMVRPRGGDFLYS
ETEYRSMLADVAALRDLGVPGVVFGCLNADGTIDEKRMGELTEAAGPLNVTCHRAFDMTRDPAEALEALIRCKVGRVLTS
GQRDSAIEGLPLLADLVRQAGDRIIILGCGGLDLANIAEVRRKTGLAEMHFAALKDVPSTMRYRNPKVGMGGSDLDREYR
NTLTDTPLVAATIAAAKA

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=243, Percent_Identity=43.2098765432099, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI87081995, Length=238, Percent_Identity=42.436974789916, Blast_Score=186, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17556905, Length=250, Percent_Identity=33.2, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21355415, Length=252, Percent_Identity=36.1111111111111, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_RHILO (Q98L96)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102781.1
- ProteinModelPortal:   Q98L96
- SMR:   Q98L96
- GeneID:   1225444
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr1122
- NMPDR:   fig|266835.1.peg.886
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 27489; Mature: 27489

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWIDPLTTETRLPLIEICVEGIDGLLAAQAAGADRVELCASLVEGGITPSLGTVRAALD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
QATVPFHVMVRPRGGDFLYSETEYRSMLADVAALRDLGVPGVVFGCLNADGTIDEKRMGE
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHH
LTEAAGPLNVTCHRAFDMTRDPAEALEALIRCKVGRVLTSGQRDSAIEGLPLLADLVRQA
HHHCCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHC
GDRIIILGCGGLDLANIAEVRRKTGLAEMHFAALKDVPSTMRYRNPKVGMGGSDLDREYR
CCEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHH
NTLTDTPLVAATIAAAKA
HHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDWIDPLTTETRLPLIEICVEGIDGLLAAQAAGADRVELCASLVEGGITPSLGTVRAALD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
QATVPFHVMVRPRGGDFLYSETEYRSMLADVAALRDLGVPGVVFGCLNADGTIDEKRMGE
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHH
LTEAAGPLNVTCHRAFDMTRDPAEALEALIRCKVGRVLTSGQRDSAIEGLPLLADLVRQA
HHHCCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHC
GDRIIILGCGGLDLANIAEVRRKTGLAEMHFAALKDVPSTMRYRNPKVGMGGSDLDREYR
CCEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHH
NTLTDTPLVAATIAAAKA
HHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968