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The map label for this gene is tsf

Identifier: 13470845

GI number: 13470845

Start: 512441

End: 513361

Strand: Reverse

Name: tsf

Synonym: mll0650

Alternate gene names: 13470845

Gene position: 513361-512441 (Counterclockwise)

Preceding gene: 13470846

Following gene: 13470843

Centisome position: 7.3

GC content: 62.98

Gene sequence:

>921_bases
ATGAGCATTTCGGCTGCACAGGTCAAAGAACTCCGCGACTTGACCGGCGCGGGCATGATGGACTGCAAGGCGGCGTTGAA
CGAGACGAACGGCAACATGGAAGAGGCCGTCGACTGGCTGCGCAAGAAGGGCATCTCCAAGGCTGACAAGAAGGCCGGCC
GTACCGCGGCCGAAGGCCTGATCGGCGTCGATGCCGGCGTGCGCGAAGCTGCCGTCGTCGAGGTCAATTCCGAGACCGAC
TTCGTTGCCCGCAACGCCGCGTTCCAGGAGATCGTCGCCAACGTTGCCAAGGTTGCTCTCGCCTATGGCACGACGGAAGC
CGTGGCTGCCGCGAAGTATCCGGGTTCGGACAAGTCGGTGACCGACACCATCAAGGATGCTGTTGGCACCATCGGCGAGA
ATCTGGGCTTCCGCCGCTCCGCCAAGCTGACGGTTCCGCATGGCGCGGTTGCGACCTATGTCCACAACGCGGTTGCCGAC
GGCCTTGGCAAGCTCGGCGTGCTGGTTGCGATCGAAACCACAGGCAATGAACATGCCGCCAACGCCTTTGGCCGTCAGGT
CGCCATGCATGTCGCCGCCACCAACCCGATGGCGCTGACGGCGGAGCAGATCGATCCGGCAGCGGTCGAGCGCGAGAAGG
CGATCTTCTCCGATCAGGCGCGCCAGTCCGGCAAGCCGGAAGCGATCATCGAAAAGATGGTCGAGGGCCGGATGCGCAAG
TTCTACGAGGAAGTCGTGCTCCTGAAGCAGGCCTTCGTGCTCAATCCCGACATCACCGTCGAGAAGGCGCTGAAGGATGC
CGAGAAGGAAATCGGCGCGCCGGCCAAGATCACCGCCTATCTGCGCTTCGCGCTCGGCGAAGGCATCGAGAAGGAAGAGA
CCGATTTCGCGGCGGAAGTCGCTGCGGCGGTCAAGAAGTAA

Upstream 100 bases:

>100_bases
GCCGGTTCCGGCCTTCATCTTTCTAATATTTTGGCACGCTAAACGGACGCATCATCGAGTACCGGTGGTGCGTCGGTGCA
TTTAAAACAAAGAGGCGACA

Downstream 100 bases:

>100_bases
ACTTCCTACCGCTTTATTCCGAAAGCGTTTTTCGGCCGGATGTCCGCAGGGATGTCCGGCCGATTTCTTGTGCGGTGTCG
ATAAAGGCCCGCAGTTTCGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSISAAQVKELRDLTGAGMMDCKAALNETNGNMEEAVDWLRKKGISKADKKAGRTAAEGLIGVDAGVREAAVVEVNSETD
FVARNAAFQEIVANVAKVALAYGTTEAVAAAKYPGSDKSVTDTIKDAVGTIGENLGFRRSAKLTVPHGAVATYVHNAVAD
GLGKLGVLVAIETTGNEHAANAFGRQVAMHVAATNPMALTAEQIDPAAVEREKAIFSDQARQSGKPEAIIEKMVEGRMRK
FYEEVVLLKQAFVLNPDITVEKALKDAEKEIGAPAKITAYLRFALGEGIEKEETDFAAEVAAAVKK

Sequences:

>Translated_306_residues
MSISAAQVKELRDLTGAGMMDCKAALNETNGNMEEAVDWLRKKGISKADKKAGRTAAEGLIGVDAGVREAAVVEVNSETD
FVARNAAFQEIVANVAKVALAYGTTEAVAAAKYPGSDKSVTDTIKDAVGTIGENLGFRRSAKLTVPHGAVATYVHNAVAD
GLGKLGVLVAIETTGNEHAANAFGRQVAMHVAATNPMALTAEQIDPAAVEREKAIFSDQARQSGKPEAIIEKMVEGRMRK
FYEEVVLLKQAFVLNPDITVEKALKDAEKEIGAPAKITAYLRFALGEGIEKEETDFAAEVAAAVKK
>Mature_305_residues
SISAAQVKELRDLTGAGMMDCKAALNETNGNMEEAVDWLRKKGISKADKKAGRTAAEGLIGVDAGVREAAVVEVNSETDF
VARNAAFQEIVANVAKVALAYGTTEAVAAAKYPGSDKSVTDTIKDAVGTIGENLGFRRSAKLTVPHGAVATYVHNAVADG
LGKLGVLVAIETTGNEHAANAFGRQVAMHVAATNPMALTAEQIDPAAVEREKAIFSDQARQSGKPEAIIEKMVEGRMRKF
YEEVVLLKQAFVLNPDITVEKALKDAEKEIGAPAKITAYLRFALGEGIEKEETDFAAEVAAAVKK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=226, Percent_Identity=33.1858407079646, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI291084500, Length=259, Percent_Identity=30.1158301158301, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI291084498, Length=91, Percent_Identity=45.0549450549451, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI291084502, Length=93, Percent_Identity=44.0860215053763, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1786366, Length=304, Percent_Identity=43.75, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17561440, Length=300, Percent_Identity=27, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19921466, Length=307, Percent_Identity=27.3615635179153, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_RHILO (Q98MB3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102414.1
- ProteinModelPortal:   Q98MB3
- SMR:   Q98MB3
- GeneID:   1225077
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0650
- NMPDR:   fig|266835.1.peg.519
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 32359; Mature: 32228

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISAAQVKELRDLTGAGMMDCKAALNETNGNMEEAVDWLRKKGISKADKKAGRTAAEGL
CCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCHHHCCC
IGVDAGVREAAVVEVNSETDFVARNAAFQEIVANVAKVALAYGTTEAVAAAKYPGSDKSV
EECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHH
TDTIKDAVGTIGENLGFRRSAKLTVPHGAVATYVHNAVADGLGKLGVLVAIETTGNEHAA
HHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHH
NAFGRQVAMHVAATNPMALTAEQIDPAAVEREKAIFSDQARQSGKPEAIIEKMVEGRMRK
HHHHHHHHHHHCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FYEEVVLLKQAFVLNPDITVEKALKDAEKEIGAPAKITAYLRFALGEGIEKEETDFAAEV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AAAVKK
HHHHCC
>Mature Secondary Structure 
SISAAQVKELRDLTGAGMMDCKAALNETNGNMEEAVDWLRKKGISKADKKAGRTAAEGL
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCHHHCCC
IGVDAGVREAAVVEVNSETDFVARNAAFQEIVANVAKVALAYGTTEAVAAAKYPGSDKSV
EECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHH
TDTIKDAVGTIGENLGFRRSAKLTVPHGAVATYVHNAVADGLGKLGVLVAIETTGNEHAA
HHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHH
NAFGRQVAMHVAATNPMALTAEQIDPAAVEREKAIFSDQARQSGKPEAIIEKMVEGRMRK
HHHHHHHHHHHCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FYEEVVLLKQAFVLNPDITVEKALKDAEKEIGAPAKITAYLRFALGEGIEKEETDFAAEV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AAAVKK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968