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The map label for this gene is yajO [H]

Identifier: 13470842

GI number: 13470842

Start: 509691

End: 510800

Strand: Reverse

Name: yajO [H]

Synonym: mll0645

Alternate gene names: 13470842

Gene position: 510800-509691 (Counterclockwise)

Preceding gene: 13470843

Following gene: 13470841

Centisome position: 7.26

GC content: 64.86

Gene sequence:

>1110_bases
ATGACCATGACCTATTACACGCTCGGCAACAGTGGCCTCAGGGTCAGCCGGCTGGCGCTGGGCACGATGACCTTCGGTAA
GGAATGGGGCTGGGGAGCCGACAGGGACACCGCCCGCGCGATGTTCGACGCCTACGTCGAGGCAGGCGGCAATTTCTTCG
ACACGGCGGACCTCTACACCGGCGGCACGGCCGAAGCCTGGCTTGGCGAGTTCATCGCCGAGCGCGGTTTGCGCGACACC
GCGGTGATCGCCAGCAAGTTCACCATGAACATGCAGCCGGGCAATCCGAATGCTGGCGGCAACGGCCGCAAGAACATCTT
GCGCGCGGTCGATGCTTCGCTGAAACGGCTGGGCACCGACTATATCGATCTCTATCTCATGCATGTGTGGGACAGGCTGA
CGCCGGCCGAAGAGGTCATGCGCACGCTTGATGACCTGGTGCGGATGGGCAAGGTGCGCCATGTCGGCCTGTCCGATGTG
CCGGCCTGGTATGCGGGACGGGCACAGGCGATCGCCGAGCTGCGCGGGTATGAGCCGGTTTCGGCCCTGCAGCTCGAATA
TTCCCTGGCCGAGCGCGCGATCGAGAACGAGTTCGTGCCTTTCGGCACGCGCCATGGCGCCGGCATCATGGTCTGGAGCC
CGCTGGCCAGCGGGCTGCTCAGCGGCAAGTATCGCCCGGCTCAGGCCGGAAACGCCGGCCGGCTCGACGGTTTCCGCAAT
TCGACGCATCCGGGATTCCAGAAATTCACGGAGCGCAACTGGGCCATTGTGGCCGAACTCGAAAAGGTCGCATCCGAGCT
CGGCCGCGGCATGCCACAGGTCGCGATCAACTGGGTGGCGACGCAGCCGGGGATTGCCACCGTCATCCTTGGTGCGACCA
CGCTTGCCCAGATACAGGACAATCTTGGCGCGCTGGACTTCGAGATTCCGGCAACGCTTCGCGATCGGCTGGATTCGGTC
AGCAGAACGCCGGCGCCGTTCCCCTATTCCTATTTCGGGCCGCAGATACAGGCGCGCGTCACAGGCGGTGCAGCAACCGG
TGACAAGCCCTCCGGCTATGCGTCGCCGGTGCTTGTCGAGGGCGAGCCGGCCAGCGTGTCGACCGACTGA

Upstream 100 bases:

>100_bases
ACGCATGAGCGCGGCAACCCCTGGGTCAAGGCAACGCCCGGCAATGACACGGCGGGCCAGTGACGCCACGGCATTCACCA
GCAAGCATTGGAAGACGATC

Downstream 100 bases:

>100_bases
TCGATCCGGCAGGCTGCCACCAATTTGCCGGTCGGGCGCCGCGTGACATCGCGGCGCCCTTCGTGTATCGGAACTCGGCA
TCGCGCCAATGTTCGGGGTG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTMTYYTLGNSGLRVSRLALGTMTFGKEWGWGADRDTARAMFDAYVEAGGNFFDTADLYTGGTAEAWLGEFIAERGLRDT
AVIASKFTMNMQPGNPNAGGNGRKNILRAVDASLKRLGTDYIDLYLMHVWDRLTPAEEVMRTLDDLVRMGKVRHVGLSDV
PAWYAGRAQAIAELRGYEPVSALQLEYSLAERAIENEFVPFGTRHGAGIMVWSPLASGLLSGKYRPAQAGNAGRLDGFRN
STHPGFQKFTERNWAIVAELEKVASELGRGMPQVAINWVATQPGIATVILGATTLAQIQDNLGALDFEIPATLRDRLDSV
SRTPAPFPYSYFGPQIQARVTGGAATGDKPSGYASPVLVEGEPASVSTD

Sequences:

>Translated_369_residues
MTMTYYTLGNSGLRVSRLALGTMTFGKEWGWGADRDTARAMFDAYVEAGGNFFDTADLYTGGTAEAWLGEFIAERGLRDT
AVIASKFTMNMQPGNPNAGGNGRKNILRAVDASLKRLGTDYIDLYLMHVWDRLTPAEEVMRTLDDLVRMGKVRHVGLSDV
PAWYAGRAQAIAELRGYEPVSALQLEYSLAERAIENEFVPFGTRHGAGIMVWSPLASGLLSGKYRPAQAGNAGRLDGFRN
STHPGFQKFTERNWAIVAELEKVASELGRGMPQVAINWVATQPGIATVILGATTLAQIQDNLGALDFEIPATLRDRLDSV
SRTPAPFPYSYFGPQIQARVTGGAATGDKPSGYASPVLVEGEPASVSTD
>Mature_368_residues
TMTYYTLGNSGLRVSRLALGTMTFGKEWGWGADRDTARAMFDAYVEAGGNFFDTADLYTGGTAEAWLGEFIAERGLRDTA
VIASKFTMNMQPGNPNAGGNGRKNILRAVDASLKRLGTDYIDLYLMHVWDRLTPAEEVMRTLDDLVRMGKVRHVGLSDVP
AWYAGRAQAIAELRGYEPVSALQLEYSLAERAIENEFVPFGTRHGAGIMVWSPLASGLLSGKYRPAQAGNAGRLDGFRNS
THPGFQKFTERNWAIVAELEKVASELGRGMPQVAINWVATQPGIATVILGATTLAQIQDNLGALDFEIPATLRDRLDSVS
RTPAPFPYSYFGPQIQARVTGGAATGDKPSGYASPVLVEGEPASVSTD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=344, Percent_Identity=34.3023255813954, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI27436964, Length=344, Percent_Identity=34.3023255813954, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI27436966, Length=344, Percent_Identity=34.0116279069767, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI27436969, Length=324, Percent_Identity=32.7160493827161, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI4504825, Length=322, Percent_Identity=32.6086956521739, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI27436971, Length=316, Percent_Identity=31.3291139240506, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI223718702, Length=307, Percent_Identity=28.9902280130293, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI41327764, Length=303, Percent_Identity=29.042904290429, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI41152114, Length=313, Percent_Identity=28.1150159744409, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI223718708, Length=201, Percent_Identity=30.8457711442786, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081735, Length=312, Percent_Identity=35.2564102564103, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789199, Length=355, Percent_Identity=32.3943661971831, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789375, Length=320, Percent_Identity=31.875, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=28.5276073619632, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788081, Length=307, Percent_Identity=32.2475570032573, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI48994888, Length=299, Percent_Identity=26.7558528428094, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=31.5315315315315, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=30.9446254071661, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6325169, Length=320, Percent_Identity=33.4375, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319951, Length=332, Percent_Identity=27.4096385542169, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=29.368029739777, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321052, Length=151, Percent_Identity=39.0728476821192, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45549126, Length=334, Percent_Identity=25.1497005988024, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24640980, Length=334, Percent_Identity=25.1497005988024, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646155, Length=348, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646159, Length=311, Percent_Identity=26.3665594855305, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39938; Mature: 39806

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTYYTLGNSGLRVSRLALGTMTFGKEWGWGADRDTARAMFDAYVEAGGNFFDTADLYT
CEEEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCC
GGTAEAWLGEFIAERGLRDTAVIASKFTMNMQPGNPNAGGNGRKNILRAVDASLKRLGTD
CCCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCH
YIDLYLMHVWDRLTPAEEVMRTLDDLVRMGKVRHVGLSDVPAWYAGRAQAIAELRGYEPV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCCH
SALQLEYSLAERAIENEFVPFGTRHGAGIMVWSPLASGLLSGKYRPAQAGNAGRLDGFRN
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCC
STHPGFQKFTERNWAIVAELEKVASELGRGMPQVAINWVATQPGIATVILGATTLAQIQD
CCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCEEEHHHHHHHHHHHH
NLGALDFEIPATLRDRLDSVSRTPAPFPYSYFGPQIQARVTGGAATGDKPSGYASPVLVE
CCCCEEEECCHHHHHHHHHHHCCCCCCCCHHCCCEEEEEEECCCCCCCCCCCCCCCEEEC
GEPASVSTD
CCCCCCCCC
>Mature Secondary Structure 
TMTYYTLGNSGLRVSRLALGTMTFGKEWGWGADRDTARAMFDAYVEAGGNFFDTADLYT
EEEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCC
GGTAEAWLGEFIAERGLRDTAVIASKFTMNMQPGNPNAGGNGRKNILRAVDASLKRLGTD
CCCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCH
YIDLYLMHVWDRLTPAEEVMRTLDDLVRMGKVRHVGLSDVPAWYAGRAQAIAELRGYEPV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCCH
SALQLEYSLAERAIENEFVPFGTRHGAGIMVWSPLASGLLSGKYRPAQAGNAGRLDGFRN
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCC
STHPGFQKFTERNWAIVAELEKVASELGRGMPQVAINWVATQPGIATVILGATTLAQIQD
CCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCEEEHHHHHHHHHHHH
NLGALDFEIPATLRDRLDSVSRTPAPFPYSYFGPQIQARVTGGAATGDKPSGYASPVLVE
CCCCEEEECCHHHHHHHHHHHCCCCCCCCHHCCCEEEEEEECCCCCCCCCCCCCCCEEEC
GEPASVSTD
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]