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The map label for this gene is yaeL [C]

Identifier: 13470837

GI number: 13470837

Start: 505327

End: 506367

Strand: Reverse

Name: yaeL [C]

Synonym: mll0638

Alternate gene names: 13470837

Gene position: 506367-505327 (Counterclockwise)

Preceding gene: 13470838

Following gene: 13470836

Centisome position: 7.2

GC content: 62.25

Gene sequence:

>1041_bases
ATGGGCCACTACCTCGTCGGCCGGTGGTGCGGCATCGGGGTCAGGGCCTTCTCGATCGGCTTCGGTCCCGAACTCATCGG
CTTCAATGACCGGCATGGCACGCGCTGGAAGCTTTGCGCCATACCGCTTGGCGGCTATGTCAAATTTGTCGGCGACATGA
ACGCCACCTCCAGCCAGCCCACGTCGGAAGAGCTGGAGACGCTGACCGACGAGGAGCGCAAGGTCGCCTTCCACACACAG
GCCATCTGGAAGCGTGCGGCGACGGTGGTGGCCGGGCCTCTGTTCAATTTCCTGCTGACGATCGTCGTCTTTTCCGTGCT
GTTTGCCTCCTATGGGCGCTATGTCGCAGAGCCCATGGTGGCTGAAGTCACGGCAGACAGTCCGGCGGCAAAGGCCGGCA
TCCAGCCTGGCGATCGATTCGTCAGTGTCGACGGCAGCAAGGTCGAAACCTTTGGCGATGTGCAGCGGCTGGTGTCGGGC
CGCGCCGGCGATACCATCACCTTTGTCATGCTGCGCGACGGCAAGGAAGTCACGGTGACCGCGACGCCGCAGTTGATGGA
GCAGCAAGACGCGCTCGGCAACAAGGTCAAGGTCGCCGTGATCGGCGTCGTCAACAACAAGGAACTCGGTCAGCCTCGTC
TCATCACCTACACGCCGGTCGGGGCGGTTGCGGCGGCAGTTGAGGAAACAGGCCACGTCATCCAGCGCACCGGCCAGTTC
TTGCAGCGTTTCGCCGTCGGGCGCGAGGACAAGTGTCAGTTGGGCGGTCCCGTCAAGATCGCGGACATGGCCGGCAAGGC
GGCGAAACTCGGTTTCGAATGGCTGGTGCAGCTCGTCGCGCTGCTCTCCGTCGGCATAGGTTTTCTAAACCTTTTGCCGA
TTCCCCCCCTCGACGGCGGCCATCTGTTGTTCTACGGGGTGGAGGCCGTCATTCGCCGGCCGGTGTCGGAACGGATGATG
GAAATGGCCTATCGGGCCGGTCTGCTTCTGGTCTTGTGCTTCATGGGTTTCGTGTTCTGGAACGATCTGTTTGGATGCTG
A

Upstream 100 bases:

>100_bases
GAACGGGATTCTTCACGCGATTTTCAGCACGGAAGGCTTGTTTCTCGGCACGCTCGTGCCGTTTCTGTTCGTGCTGACCG
TGGTGGTGTTCGTCCACGAG

Downstream 100 bases:

>100_bases
AATCATGAAGAAATTTGGCTTTGGCATGGTCGATGTTGAGACGCCGTTTACCATGCACGGGGATATGAGTGACGCGAAAG
CCACGCACCAGGGTTAAGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MGHYLVGRWCGIGVRAFSIGFGPELIGFNDRHGTRWKLCAIPLGGYVKFVGDMNATSSQPTSEELETLTDEERKVAFHTQ
AIWKRAATVVAGPLFNFLLTIVVFSVLFASYGRYVAEPMVAEVTADSPAAKAGIQPGDRFVSVDGSKVETFGDVQRLVSG
RAGDTITFVMLRDGKEVTVTATPQLMEQQDALGNKVKVAVIGVVNNKELGQPRLITYTPVGAVAAAVEETGHVIQRTGQF
LQRFAVGREDKCQLGGPVKIADMAGKAAKLGFEWLVQLVALLSVGIGFLNLLPIPPLDGGHLLFYGVEAVIRRPVSERMM
EMAYRAGLLLVLCFMGFVFWNDLFGC

Sequences:

>Translated_346_residues
MGHYLVGRWCGIGVRAFSIGFGPELIGFNDRHGTRWKLCAIPLGGYVKFVGDMNATSSQPTSEELETLTDEERKVAFHTQ
AIWKRAATVVAGPLFNFLLTIVVFSVLFASYGRYVAEPMVAEVTADSPAAKAGIQPGDRFVSVDGSKVETFGDVQRLVSG
RAGDTITFVMLRDGKEVTVTATPQLMEQQDALGNKVKVAVIGVVNNKELGQPRLITYTPVGAVAAAVEETGHVIQRTGQF
LQRFAVGREDKCQLGGPVKIADMAGKAAKLGFEWLVQLVALLSVGIGFLNLLPIPPLDGGHLLFYGVEAVIRRPVSERMM
EMAYRAGLLLVLCFMGFVFWNDLFGC
>Mature_345_residues
GHYLVGRWCGIGVRAFSIGFGPELIGFNDRHGTRWKLCAIPLGGYVKFVGDMNATSSQPTSEELETLTDEERKVAFHTQA
IWKRAATVVAGPLFNFLLTIVVFSVLFASYGRYVAEPMVAEVTADSPAAKAGIQPGDRFVSVDGSKVETFGDVQRLVSGR
AGDTITFVMLRDGKEVTVTATPQLMEQQDALGNKVKVAVIGVVNNKELGQPRLITYTPVGAVAAAVEETGHVIQRTGQFL
QRFAVGREDKCQLGGPVKIADMAGKAAKLGFEWLVQLVALLSVGIGFLNLLPIPPLDGGHLLFYGVEAVIRRPVSERMME
MAYRAGLLLVLCFMGFVFWNDLFGC

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=237, Percent_Identity=32.4894514767932, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y638_RHILO (Q98MC1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102406.1
- ProteinModelPortal:   Q98MC1
- MEROPS:   M50.004
- GeneID:   1225069
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0638
- NMPDR:   fig|266835.1.peg.511
- HOGENOM:   HBG664087
- ProtClustDB:   CLSK863040
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 37533; Mature: 37402

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 21-21

Signals:

None

Transmembrane regions:

HASH(0xcb8363c)-; HASH(0xd7a3cc4)-; HASH(0xd4e73ec)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHYLVGRWCGIGVRAFSIGFGPELIGFNDRHGTRWKLCAIPLGGYVKFVGDMNATSSQP
CCCCEEEHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCC
TSEELETLTDEERKVAFHTQAIWKRAATVVAGPLFNFLLTIVVFSVLFASYGRYVAEPMV
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AEVTADSPAAKAGIQPGDRFVSVDGSKVETFGDVQRLVSGRAGDTITFVMLRDGKEVTVT
HEECCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEE
ATPQLMEQQDALGNKVKVAVIGVVNNKELGQPRLITYTPVGAVAAAVEETGHVIQRTGQF
ECHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
LQRFAVGREDKCQLGGPVKIADMAGKAAKLGFEWLVQLVALLSVGIGFLNLLPIPPLDGG
HHHHHCCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HLLFYGVEAVIRRPVSERMMEMAYRAGLLLVLCFMGFVFWNDLFGC
EEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
GHYLVGRWCGIGVRAFSIGFGPELIGFNDRHGTRWKLCAIPLGGYVKFVGDMNATSSQP
CCCEEEHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCC
TSEELETLTDEERKVAFHTQAIWKRAATVVAGPLFNFLLTIVVFSVLFASYGRYVAEPMV
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AEVTADSPAAKAGIQPGDRFVSVDGSKVETFGDVQRLVSGRAGDTITFVMLRDGKEVTVT
HEECCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEE
ATPQLMEQQDALGNKVKVAVIGVVNNKELGQPRLITYTPVGAVAAAVEETGHVIQRTGQF
ECHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
LQRFAVGREDKCQLGGPVKIADMAGKAAKLGFEWLVQLVALLSVGIGFLNLLPIPPLDGG
HHHHHCCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HLLFYGVEAVIRRPVSERMMEMAYRAGLLLVLCFMGFVFWNDLFGC
EEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968