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The map label for this gene is yafC [H]

Identifier: 13470511

GI number: 13470511

Start: 168617

End: 169513

Strand: Reverse

Name: yafC [H]

Synonym: mll0238

Alternate gene names: 13470511

Gene position: 169513-168617 (Counterclockwise)

Preceding gene: 13470516

Following gene: 13470509

Centisome position: 2.41

GC content: 60.87

Gene sequence:

>897_bases
ATGGATCTCGAAGCCTTGGCTGACTTCAATCTCGTTGCCGCCCACGGCGGCTTCGGCCGGGCCGGTCGCATCTCCGGCCG
ATCCAAGGCGACATTGTCGCGCCATGTGAACGAACTTGAGCATAGCCTTGGCGTGAGGCTGATCGAGCGTGGATCCCAAA
GTCTGCGACTGACGGACGAAGGGCGAGCGCTTTACGAGCGCACGGACGGATTGATGGCGGAAATCGCGGAGGCGGGAGAG
GCGATTGTTCTAGGCGCGTCCACACCCCGGGGCAGGCTGCGGGTGAGCGCTCCCGTGGTTTTCGCGCATGTTGCGCTTCC
CATGATCGGCACCCGTTTCGCTCTCGCCTATCCGGAGGTGAAGCTTGAGATTGTTGCCGAGGATCGCAAGGTCGATCCGG
TCGAGGATGGCTACGACCTAGTTATCCGGATCGATCCTTCACCGGATGAACGGCTCATCGGTCGCCGTTTTCTCAATGAC
GAGCGGCTGATTGTTGCCTTGCCGGATATGCCGCGCCCTCAGCCGGCGCCGGGCGGCGGACCGAGCCCGGTAAAGGCCGT
TTTGCTGAGCGCAACGTCGCTGAACGTGGTTTGGCGCCTCAAATTCGATTTTGAGGACGAAATCCTTTTGAAGCCCGAGC
CAATCCTGCGCTTCTCGTCTCTGCTGATGGTGCGCGATGCCGTTCTGGCTGGTGCGGGCGCGGCATTGCTTCCGAAGCTT
CTTGTCGCAGGCGACATCGAGGCGGGCCGCCTTGTTTGTTGGGGAACTGATGCCGGTCCGCCTGTCGAGATCTGGGCGCT
CCAAAGTTCGCGACGGCTTATCGGTGCGAAGGTTCGCGCTTTCCTGGATGTGATGGAGAGAGCATTTCCCACCAAAGTTT
TCGTTTCTGCACCCTGA

Upstream 100 bases:

>100_bases
TCCTTGTGGTGTTTGTGCGTGTCCAGGGAAAGATAGACGTTCCAATCTTGAGCGGGAGATGGCATGTTCAAAACAACTCG
TCTCAATATTGGAACACATC

Downstream 100 bases:

>100_bases
ACCAGAACCTGTCCTGCCGGCCAGGCGCCTCCCCGTTTTTAGGATGAAGTCGGTTTCCCGGCACGGCCATACTGGCGTGG
TGTACAGCCCATGACCCTCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDLEALADFNLVAAHGGFGRAGRISGRSKATLSRHVNELEHSLGVRLIERGSQSLRLTDEGRALYERTDGLMAEIAEAGE
AIVLGASTPRGRLRVSAPVVFAHVALPMIGTRFALAYPEVKLEIVAEDRKVDPVEDGYDLVIRIDPSPDERLIGRRFLND
ERLIVALPDMPRPQPAPGGGPSPVKAVLLSATSLNVVWRLKFDFEDEILLKPEPILRFSSLLMVRDAVLAGAGAALLPKL
LVAGDIEAGRLVCWGTDAGPPVEIWALQSSRRLIGAKVRAFLDVMERAFPTKVFVSAP

Sequences:

>Translated_298_residues
MDLEALADFNLVAAHGGFGRAGRISGRSKATLSRHVNELEHSLGVRLIERGSQSLRLTDEGRALYERTDGLMAEIAEAGE
AIVLGASTPRGRLRVSAPVVFAHVALPMIGTRFALAYPEVKLEIVAEDRKVDPVEDGYDLVIRIDPSPDERLIGRRFLND
ERLIVALPDMPRPQPAPGGGPSPVKAVLLSATSLNVVWRLKFDFEDEILLKPEPILRFSSLLMVRDAVLAGAGAALLPKL
LVAGDIEAGRLVCWGTDAGPPVEIWALQSSRRLIGAKVRAFLDVMERAFPTKVFVSAP
>Mature_298_residues
MDLEALADFNLVAAHGGFGRAGRISGRSKATLSRHVNELEHSLGVRLIERGSQSLRLTDEGRALYERTDGLMAEIAEAGE
AIVLGASTPRGRLRVSAPVVFAHVALPMIGTRFALAYPEVKLEIVAEDRKVDPVEDGYDLVIRIDPSPDERLIGRRFLND
ERLIVALPDMPRPQPAPGGGPSPVKAVLLSATSLNVVWRLKFDFEDEILLKPEPILRFSSLLMVRDAVLAGAGAALLPKL
LVAGDIEAGRLVCWGTDAGPPVEIWALQSSRRLIGAKVRAFLDVMERAFPTKVFVSAP

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=32.2033898305085, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=28.7162162162162, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=27.3648648648649, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI145693193, Length=153, Percent_Identity=31.3725490196078, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789173, Length=263, Percent_Identity=30.7984790874525, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=26.8456375838926, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789440, Length=271, Percent_Identity=23.9852398523985, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788706, Length=175, Percent_Identity=26.2857142857143, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786448, Length=265, Percent_Identity=28.3018867924528, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32305; Mature: 32305

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEALADFNLVAAHGGFGRAGRISGRSKATLSRHVNELEHSLGVRLIERGSQSLRLTDE
CCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GRALYERTDGLMAEIAEAGEAIVLGASTPRGRLRVSAPVVFAHVALPMIGTRFALAYPEV
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHEEHHHHHHHCCEEEEECCCE
KLEIVAEDRKVDPVEDGYDLVIRIDPSPDERLIGRRFLNDERLIVALPDMPRPQPAPGGG
EEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
PSPVKAVLLSATSLNVVWRLKFDFEDEILLKPEPILRFSSLLMVRDAVLAGAGAALLPKL
CCHHHHHEEEEEEEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVAGDIEAGRLVCWGTDAGPPVEIWALQSSRRLIGAKVRAFLDVMERAFPTKVFVSAP
HHHCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MDLEALADFNLVAAHGGFGRAGRISGRSKATLSRHVNELEHSLGVRLIERGSQSLRLTDE
CCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GRALYERTDGLMAEIAEAGEAIVLGASTPRGRLRVSAPVVFAHVALPMIGTRFALAYPEV
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHEEHHHHHHHCCEEEEECCCE
KLEIVAEDRKVDPVEDGYDLVIRIDPSPDERLIGRRFLNDERLIVALPDMPRPQPAPGGG
EEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
PSPVKAVLLSATSLNVVWRLKFDFEDEILLKPEPILRFSSLLMVRDAVLAGAGAALLPKL
CCHHHHHEEEEEEEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVAGDIEAGRLVCWGTDAGPPVEIWALQSSRRLIGAKVRAFLDVMERAFPTKVFVSAP
HHHCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]