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The map label for this gene is aroQ

Identifier: 13470485

GI number: 13470485

Start: 139487

End: 139921

Strand: Reverse

Name: aroQ

Synonym: mll0207

Alternate gene names: 13470485

Gene position: 139921-139487 (Counterclockwise)

Preceding gene: 13470486

Following gene: 13470484

Centisome position: 1.99

GC content: 64.6

Gene sequence:

>435_bases
TTGAAAACGGTTTTCGTCCTGAACGGTCCCAATCTCAACGCGCTCGGCAAGCGCGAGCCGGGCATCTATGGCGGCAAGAC
GCTTGCCGCGATCGCTGACGACTGCAAGCAGGCCGGCGCGTCGCTCGGGCTCGGGATCGATTTCCGCCAGTCGAACCACG
AGGGTGACCTCGTCGACTGGATCCAGGAAGCCGGCGACAAGGCTGCCGGCATCGTCATCAATCCAGGCGCCTACAGCCAC
ACCTCGATCGCGATCCACGACGCCATCCGTTCGATCGCGCCGCTGCCGGTCGCCGAAGTTCACCTTTCCAACATCCATGC
GCGGGAATCATTCCGCCACGTCTCCATGGTCGCGCCGGTCGCCGTCGGCATGATCTGTGGCTTTGGGCCGCTCGGCTACA
CGCTGGCGCTACAGGCGCTGGCCGCACGCCTATGA

Upstream 100 bases:

>100_bases
CAGTGAAAGAACGCACTTGCGCTCTTTTCGCGGACGACTATGCCCGGTATAGAGGCCCAGCGCGCCGGTTTGATACCGGC
GCCGGAAAAGGTCGGGTTTT

Downstream 100 bases:

>100_bases
CTGGCCAACAAACAGAAGGCTCGAAAATGTCGATAAAGAAGACCGGTGTTGACCAGCAACTGATCCGCGATCTGGCGGGC
ATACTGAACGACACCAACCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKTVFVLNGPNLNALGKREPGIYGGKTLAAIADDCKQAGASLGLGIDFRQSNHEGDLVDWIQEAGDKAAGIVINPGAYSH
TSIAIHDAIRSIAPLPVAEVHLSNIHARESFRHVSMVAPVAVGMICGFGPLGYTLALQALAARL

Sequences:

>Translated_144_residues
MKTVFVLNGPNLNALGKREPGIYGGKTLAAIADDCKQAGASLGLGIDFRQSNHEGDLVDWIQEAGDKAAGIVINPGAYSH
TSIAIHDAIRSIAPLPVAEVHLSNIHARESFRHVSMVAPVAVGMICGFGPLGYTLALQALAARL
>Mature_144_residues
MKTVFVLNGPNLNALGKREPGIYGGKTLAAIADDCKQAGASLGLGIDFRQSNHEGDLVDWIQEAGDKAAGIVINPGAYSH
TSIAIHDAIRSIAPLPVAEVHLSNIHARESFRHVSMVAPVAVGMICGFGPLGYTLALQALAARL

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_RHILO (Q98NC1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102054.1
- ProteinModelPortal:   Q98NC1
- SMR:   Q98NC1
- GeneID:   1224717
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0207
- NMPDR:   fig|266835.1.peg.159
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15052; Mature: 15052

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 101-101 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVFVLNGPNLNALGKREPGIYGGKTLAAIADDCKQAGASLGLGIDFRQSNHEGDLVDW
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHH
IQEAGDKAAGIVINPGAYSHTSIAIHDAIRSIAPLPVAEVHLSNIHARESFRHVSMVAPV
HHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVGMICGFGPLGYTLALQALAARL
HHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTVFVLNGPNLNALGKREPGIYGGKTLAAIADDCKQAGASLGLGIDFRQSNHEGDLVDW
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHH
IQEAGDKAAGIVINPGAYSHTSIAIHDAIRSIAPLPVAEVHLSNIHARESFRHVSMVAPV
HHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVGMICGFGPLGYTLALQALAARL
HHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968