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The map label for this gene is gpt

Identifier: 13470434

GI number: 13470434

Start: 99424

End: 99924

Strand: Reverse

Name: gpt

Synonym: mll0141

Alternate gene names: 13470434

Gene position: 99924-99424 (Counterclockwise)

Preceding gene: 13470435

Following gene: 13470433

Centisome position: 1.42

GC content: 64.47

Gene sequence:

>501_bases
ATGTCCCTTCCCGAAAAAGCCTTTCCGGTCTCCTGGGACCAGTTCCATCGTGACGCCCGCGCGCTTTCCTGGCGGCTTTC
AGGCGCCAACAAGGGGCAATGGAAGGCGATCGTCTGCATCACGCGCGGCGGGCTGGTTCCGGCGGCGATCATCGCGCGCG
AACTCGGCATCCGCGTCATCGAGACGGTCTGTGTCGCCTCCTACCACGACTACACCAGCCAGGGGCAGTTGCAGGTGCTG
AAGGAGATAACGCCCGCACTGCTCGCCGACGACGGCGCCGGCGTGCTGATCATCGACGACCTGACCGACACCGGCAAGAC
CGCCGGCATCGTGCGCGCAATGATGCCCAAGGCGCATTTCGCCACCGTCTACGCCAAGCCGAAGGGCCGGCCGCTGGTCG
ATACTTTCGTCACCGAGGTCAGCCAGGATACCTGGATCTATTTCCCCTGGGACATGGGCTTCACCTACCAGAAGCCGATC
GCCGACGACCACGCCGGCTGA

Upstream 100 bases:

>100_bases
GCCAGCCGCCCTTGCCAAAGCCGAGGCTTTCCAGTTAATTCCGCGCGCATTCCCCTGTTTTTGTGCACGCGGTCTTCGCG
TGCTGCGGAGTGCGCGAAAA

Downstream 100 bases:

>100_bases
TTCGCGACACGCCGCTTTTTCCAACTAAGCAGCCACCGACGACAATATTTGCTTCCGTGGACGGCTCCCTGGGGCAGGAT
ATCCTGTGAAATCGACCTCT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSLPEKAFPVSWDQFHRDARALSWRLSGANKGQWKAIVCITRGGLVPAAIIARELGIRVIETVCVASYHDYTSQGQLQVL
KEITPALLADDGAGVLIIDDLTDTGKTAGIVRAMMPKAHFATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDMGFTYQKPI
ADDHAG

Sequences:

>Translated_166_residues
MSLPEKAFPVSWDQFHRDARALSWRLSGANKGQWKAIVCITRGGLVPAAIIARELGIRVIETVCVASYHDYTSQGQLQVL
KEITPALLADDGAGVLIIDDLTDTGKTAGIVRAMMPKAHFATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDMGFTYQKPI
ADDHAG
>Mature_165_residues
SLPEKAFPVSWDQFHRDARALSWRLSGANKGQWKAIVCITRGGLVPAAIIARELGIRVIETVCVASYHDYTSQGQLQVLK
EITPALLADDGAGVLIIDDLTDTGKTAGIVRAMMPKAHFATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDMGFTYQKPIA
DDHAG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=156, Percent_Identity=50.6410256410256, Blast_Score=160, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_RHILO (Q98NH3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102002.1
- ProteinModelPortal:   Q98NH3
- GeneID:   1224665
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0141
- NMPDR:   fig|266835.1.peg.107
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- ProtClustDB:   PRK09177
- BRENDA:   2.4.2.22
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 18277; Mature: 18146

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 103-103 BINDING 146-146

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPEKAFPVSWDQFHRDARALSWRLSGANKGQWKAIVCITRGGLVPAAIIARELGIRVI
CCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
ETVCVASYHDYTSQGQLQVLKEITPALLADDGAGVLIIDDLTDTGKTAGIVRAMMPKAHF
HHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCEEEEECCCCCCCHHHHHHHHCCCCEE
ATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDMGFTYQKPIADDHAG
EEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCC
>Mature Secondary Structure 
SLPEKAFPVSWDQFHRDARALSWRLSGANKGQWKAIVCITRGGLVPAAIIARELGIRVI
CCCCCCCCCCHHHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
ETVCVASYHDYTSQGQLQVLKEITPALLADDGAGVLIIDDLTDTGKTAGIVRAMMPKAHF
HHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCEEEEECCCCCCCHHHHHHHHCCCCEE
ATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDMGFTYQKPIADDHAG
EEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968