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The map label for this gene is uppP2

Identifier: 13470416

GI number: 13470416

Start: 82193

End: 82987

Strand: Direct

Name: uppP2

Synonym: mlr0116

Alternate gene names: 13470416

Gene position: 82193-82987 (Clockwise)

Preceding gene: 13470414

Following gene: 13470417

Centisome position: 1.17

GC content: 65.66

Gene sequence:

>795_bases
GTGCAAGGCATCACCGAATTGCTGCCGATTTCCTCGACTGCCCATATGCGCATCGTGCCGGCGCTACTCGGCTGGCAGGA
CCCGGGCTCCGCCTTCTCCGCCGCCATGCAGCTTGCCGCCCTTGCCGCCGTGATCAGCTATTTCTGGGGCGATGTCAGGG
ATCTCCTGTTCGGCTCGCTCGATGCGCTCACGAGGCGCGATTTTTCCGACCGGCATTTCCGGCTAGCGTCCTGGATCGTG
CTGGCGACGATCCCGATCGTCATTGCAGGCGTCGCGCTATCGGGCGTTCTCAATGCCTGCAATTCGCCGCTGCGCAGCCT
GACCGTGATCGGCTGGTCCTGTATCGCCATGGCGATCCTGCTGGCGCTGGCCGAGATTTTCGCCCGCCACAAGCGCACCA
TCGCAGAAGCGTCGCTCGCCGACGCGCTGCTTGTCGGCGTAGCACAGATCGGCGCGCTGATCCCCGGCGTCTCGCGCTCG
GGCTCGACCCTGACGGCGGCGCTTGGGCTCGGCTTCAAGCGGGCCGAGGCGGCGCGCTTCTCGTTCCTGCTCGGGCTGCC
GGCGATCGCGCTTGCCGGTCTCAAGGAACTGTGGGAGCTGCACAAGGTTCATCTCGACGCCCATGGCTGGTCGGTTCTTG
CCACCGGGCTGGTCGTCGCCTCGATCTCCGCCTTCTTTGCCATCTGGGGCCTGATGCGAGTGCTGGAACGCTTCTCCGCC
TGGCCTTTCGTCATCTATCGCGGCCTGCTCGGCGTGGTCTTGTTGCTCGGCCTGGCGATGGGATGGCTGGCTTGA

Upstream 100 bases:

>100_bases
TTATTCGACAGAAAGGCTCGATATGGCTGACATCTGCACTCAAGGCGTAGACACCGGCTTCGTCGGCCTGGGATTTGCCA
AGGTCGCCTTTCTCGGCCTG

Downstream 100 bases:

>100_bases
CAGCAGTGTTGCGTGCCGGCACCAGTTGAGTGCATGAGTCGATCCCCTCGCAGATGTGATCGCTAGGGTTGATTGACTTC
GGAATATAACCGCCCTTAAC

Product: integral membrane lipid kinase-like protein

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQGITELLPISSTAHMRIVPALLGWQDPGSAFSAAMQLAALAAVISYFWGDVRDLLFGSLDALTRRDFSDRHFRLASWIV
LATIPIVIAGVALSGVLNACNSPLRSLTVIGWSCIAMAILLALAEIFARHKRTIAEASLADALLVGVAQIGALIPGVSRS
GSTLTAALGLGFKRAEAARFSFLLGLPAIALAGLKELWELHKVHLDAHGWSVLATGLVVASISAFFAIWGLMRVLERFSA
WPFVIYRGLLGVVLLLGLAMGWLA

Sequences:

>Translated_264_residues
MQGITELLPISSTAHMRIVPALLGWQDPGSAFSAAMQLAALAAVISYFWGDVRDLLFGSLDALTRRDFSDRHFRLASWIV
LATIPIVIAGVALSGVLNACNSPLRSLTVIGWSCIAMAILLALAEIFARHKRTIAEASLADALLVGVAQIGALIPGVSRS
GSTLTAALGLGFKRAEAARFSFLLGLPAIALAGLKELWELHKVHLDAHGWSVLATGLVVASISAFFAIWGLMRVLERFSA
WPFVIYRGLLGVVLLLGLAMGWLA
>Mature_264_residues
MQGITELLPISSTAHMRIVPALLGWQDPGSAFSAAMQLAALAAVISYFWGDVRDLLFGSLDALTRRDFSDRHFRLASWIV
LATIPIVIAGVALSGVLNACNSPLRSLTVIGWSCIAMAILLALAEIFARHKRTIAEASLADALLVGVAQIGALIPGVSRS
GSTLTAALGLGFKRAEAARFSFLLGLPAIALAGLKELWELHKVHLDAHGWSVLATGLVVASISAFFAIWGLMRVLERFSA
WPFVIYRGLLGVVLLLGLAMGWLA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_RHILO (Q98NJ1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_101984.1
- GeneID:   1224647
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr0116
- NMPDR:   fig|266835.1.peg.89
- HOGENOM:   HBG391969
- OMA:   RYISTRT
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28110; Mature: 28110

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xc0130b8)-; HASH(0xbe83480)-; HASH(0xb712220)-; HASH(0xc04d54c)-; HASH(0xc846520)-; HASH(0xbf18004)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGITELLPISSTAHMRIVPALLGWQDPGSAFSAAMQLAALAAVISYFWGDVRDLLFGSL
CCCHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALTRRDFSDRHFRLASWIVLATIPIVIAGVALSGVLNACNSPLRSLTVIGWSCIAMAIL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LALAEIFARHKRTIAEASLADALLVGVAQIGALIPGVSRSGSTLTAALGLGFKRAEAARF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHH
SFLLGLPAIALAGLKELWELHKVHLDAHGWSVLATGLVVASISAFFAIWGLMRVLERFSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WPFVIYRGLLGVVLLLGLAMGWLA
CHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQGITELLPISSTAHMRIVPALLGWQDPGSAFSAAMQLAALAAVISYFWGDVRDLLFGSL
CCCHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALTRRDFSDRHFRLASWIVLATIPIVIAGVALSGVLNACNSPLRSLTVIGWSCIAMAIL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LALAEIFARHKRTIAEASLADALLVGVAQIGALIPGVSRSGSTLTAALGLGFKRAEAARF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHH
SFLLGLPAIALAGLKELWELHKVHLDAHGWSVLATGLVVASISAFFAIWGLMRVLERFSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WPFVIYRGLLGVVLLLGLAMGWLA
CHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968