Click here to switch to the map view.

The map label for this gene is yodT [H]

Identifier: 13470408

GI number: 13470408

Start: 75072

End: 76457

Strand: Reverse

Name: yodT [H]

Synonym: mll0107

Alternate gene names: 13470408

Gene position: 76457-75072 (Counterclockwise)

Preceding gene: 13470409

Following gene: 13470407

Centisome position: 1.09

GC content: 65.08

Gene sequence:

>1386_bases
ATGTCGAAGACCCAGACCGCCGACCAAATCACCGAGGCGCGCCGAGAATCGCATCTGTTCTACCTGTCCAGCCTGCGCCG
GCCGCTGATCGATCGCGCCGAGGGTATCTACATGTGGACGCAAGACGGGCGCCGCTTCATCGACGGATCAAGCGGCCCGA
TGGTCGCCAATATCGGCCATTCCAACCGCAATGTGCTCGATGCCATGAAGCGGCAGATGGACCGCGCCACCTTCGCCTAT
CGCCTGCACTTCGAAAACGAGCCGGCGGAGGAACTCGCGCGGGAACTCGCGAAGAAACTGCCGGAGGGCATGGACCGCAT
CTTCTTCGTCTCCGGTGGCTCGGAAGCGACGGAATCCTGCATCAAGCTGGCACGGCAATGGGCTGTTGCCACCGGCCAGG
CCAGCCGCTGGAAGGTGATCACGCGCTTCCCCTCCTATCATGGCGGCACGCTGGGTTCACTCTCGATCACCGGCGACGAC
GCCCTGGCCGAAACCTTCGAGCCGATGATGCGGGTGATGCCGACCGTGCCGGCGCCCACCGCCTGGCGCGACCGCGACAA
TCTTTCGATGGAGCAGCGCGGTGTCCGCTATGCCGACATGCTGGAGGAAAAAATCCTCGCGGAAGGACCGGAAAGTGTCG
TCGCCTTCATCATGGAGCCGATCGGCGGTGCGGCGACTGCGGCGCTGGTGGCGCCGGACAGCTACTATGCGCGCACTCGC
GAGATCTGCGACCACTACGGCATCCTGCTCATCCATGACGAAGTGATGTGCGGCGCCGGCCGCACCGGGAAATTCCTCGG
CGGCGACCACTGGAACTGCAAGCCCGACATCGTCGCGCTGTCGAAGGGGCTGGGTTCTGGCTATGCCCCGCTCGGCGCAC
TGGCGGCCCCGATGCGGCTGGTGCAGCCGCTGCTTGCTTCCGGCGGCTTCCAGCATGGCCATACCTATGCCGGCAATCCG
CTGGCCTGCGCCGCTGGGCTTGCCGTGCTCGGCGAAATGGACCGGCTCGACTTGATCGCCAATGCCGCCGCCATGGGCGA
CGTGCTGATGGACGGGCTGAAGGGGCTGGCGAAGCGCTTCCCGTTCATTGCAGACGTACGCGGCAAGGGCCTGCTGACCG
GTGCCGAGATGGTCGCCGATCCGGAGACGCTGAGGCCGATCGAGCAAGGCAAGAAAGCCACGCAGCGCCTGCTCGACCTC
GCTTATGAGCGCGGGCTGATCATCTATGGCCGCCGGGTCAAGGGCGGCGTCGACGGCGACAATTTCATGGTCGCGCCACC
GATGATCGTCACCAGCGAACAGGTCGGCGAGATCATTTCCATCATCGGCGACTCGCTGGAGGTTCTGGCTTCAGAGCTCG
ACCTGCCGGTCGAAGGCCGGGGGTAA

Upstream 100 bases:

>100_bases
GCGGGAAGCTGCGAATGGGTAGCCGGCCTGCTAAGGCAGGACCCGATGGTGGAACGCGTCACCCGCAATGTCCTTGATCG
CTACCTTGGAAAGTCCTGAC

Downstream 100 bases:

>100_bases
GGAATGGCGCCGCGCAAAGTCATCATCACCTGCGCCGTCACCGGCTCGGTGCACACCCCATCGATGTCGCCCTACCTGCC
GGTGACCCCGGACCAGATCG

Product: aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSKTQTADQITEARRESHLFYLSSLRRPLIDRAEGIYMWTQDGRRFIDGSSGPMVANIGHSNRNVLDAMKRQMDRATFAY
RLHFENEPAEELARELAKKLPEGMDRIFFVSGGSEATESCIKLARQWAVATGQASRWKVITRFPSYHGGTLGSLSITGDD
ALAETFEPMMRVMPTVPAPTAWRDRDNLSMEQRGVRYADMLEEKILAEGPESVVAFIMEPIGGAATAALVAPDSYYARTR
EICDHYGILLIHDEVMCGAGRTGKFLGGDHWNCKPDIVALSKGLGSGYAPLGALAAPMRLVQPLLASGGFQHGHTYAGNP
LACAAGLAVLGEMDRLDLIANAAAMGDVLMDGLKGLAKRFPFIADVRGKGLLTGAEMVADPETLRPIEQGKKATQRLLDL
AYERGLIIYGRRVKGGVDGDNFMVAPPMIVTSEQVGEIISIIGDSLEVLASELDLPVEGRG

Sequences:

>Translated_461_residues
MSKTQTADQITEARRESHLFYLSSLRRPLIDRAEGIYMWTQDGRRFIDGSSGPMVANIGHSNRNVLDAMKRQMDRATFAY
RLHFENEPAEELARELAKKLPEGMDRIFFVSGGSEATESCIKLARQWAVATGQASRWKVITRFPSYHGGTLGSLSITGDD
ALAETFEPMMRVMPTVPAPTAWRDRDNLSMEQRGVRYADMLEEKILAEGPESVVAFIMEPIGGAATAALVAPDSYYARTR
EICDHYGILLIHDEVMCGAGRTGKFLGGDHWNCKPDIVALSKGLGSGYAPLGALAAPMRLVQPLLASGGFQHGHTYAGNP
LACAAGLAVLGEMDRLDLIANAAAMGDVLMDGLKGLAKRFPFIADVRGKGLLTGAEMVADPETLRPIEQGKKATQRLLDL
AYERGLIIYGRRVKGGVDGDNFMVAPPMIVTSEQVGEIISIIGDSLEVLASELDLPVEGRG
>Mature_460_residues
SKTQTADQITEARRESHLFYLSSLRRPLIDRAEGIYMWTQDGRRFIDGSSGPMVANIGHSNRNVLDAMKRQMDRATFAYR
LHFENEPAEELARELAKKLPEGMDRIFFVSGGSEATESCIKLARQWAVATGQASRWKVITRFPSYHGGTLGSLSITGDDA
LAETFEPMMRVMPTVPAPTAWRDRDNLSMEQRGVRYADMLEEKILAEGPESVVAFIMEPIGGAATAALVAPDSYYARTRE
ICDHYGILLIHDEVMCGAGRTGKFLGGDHWNCKPDIVALSKGLGSGYAPLGALAAPMRLVQPLLASGGFQHGHTYAGNPL
ACAAGLAVLGEMDRLDLIANAAAMGDVLMDGLKGLAKRFPFIADVRGKGLLTGAEMVADPETLRPIEQGKKATQRLLDLA
YERGLIIYGRRVKGGVDGDNFMVAPPMIVTSEQVGEIISIIGDSLEVLASELDLPVEGRG

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=420, Percent_Identity=29.2857142857143, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=27.0022883295195, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI37574042, Length=442, Percent_Identity=28.0542986425339, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI226442705, Length=442, Percent_Identity=27.6018099547511, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226442709, Length=414, Percent_Identity=27.7777777777778, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI24119277, Length=362, Percent_Identity=27.3480662983425, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI284507298, Length=343, Percent_Identity=29.4460641399417, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI188536080, Length=459, Percent_Identity=23.0936819172113, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI38679950, Length=459, Percent_Identity=23.0936819172113, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI38679946, Length=459, Percent_Identity=23.0936819172113, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI145693181, Length=406, Percent_Identity=30.2955665024631, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI1789016, Length=424, Percent_Identity=29.0094339622642, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789759, Length=437, Percent_Identity=27.2311212814645, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1788044, Length=351, Percent_Identity=30.7692307692308, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=28.4116331096197, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=29.7619047619048, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786349, Length=308, Percent_Identity=31.4935064935065, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=457, Percent_Identity=28.6652078774617, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=27.9545454545455, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=443, Percent_Identity=26.1851015801354, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=309, Percent_Identity=30.7443365695793, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323470, Length=429, Percent_Identity=28.2051282051282, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324432, Length=378, Percent_Identity=26.1904761904762, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324386, Length=311, Percent_Identity=27.0096463022508, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357415, Length=419, Percent_Identity=31.0262529832936, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28574759, Length=453, Percent_Identity=29.8013245033113, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI161085790, Length=474, Percent_Identity=28.6919831223629, Blast_Score=155, Evalue=8e-38,
Organism=Drosophila melanogaster, GI21356575, Length=464, Percent_Identity=29.7413793103448, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281366494, Length=371, Percent_Identity=23.1805929919137, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24667139, Length=371, Percent_Identity=23.1805929919137, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24667143, Length=371, Percent_Identity=23.1805929919137, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50057; Mature: 49926

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTQTADQITEARRESHLFYLSSLRRPLIDRAEGIYMWTQDGRRFIDGSSGPMVANIGH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCEEEECCC
SNRNVLDAMKRQMDRATFAYRLHFENEPAEELARELAKKLPEGMDRIFFVSGGSEATESC
CCHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
IKLARQWAVATGQASRWKVITRFPSYHGGTLGSLSITGDDALAETFEPMMRVMPTVPAPT
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
AWRDRDNLSMEQRGVRYADMLEEKILAEGPESVVAFIMEPIGGAATAALVAPDSYYARTR
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHEEEEECCCHHHHHHH
EICDHYGILLIHDEVMCGAGRTGKFLGGDHWNCKPDIVALSKGLGSGYAPLGALAAPMRL
HHHHHCCEEEEECCEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHH
VQPLLASGGFQHGHTYAGNPLACAAGLAVLGEMDRLDLIANAAAMGDVLMDGLKGLAKRF
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFIADVRGKGLLTGAEMVADPETLRPIEQGKKATQRLLDLAYERGLIIYGRRVKGGVDGD
CEEEECCCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECEECCCCCCC
NFMVAPPMIVTSEQVGEIISIIGDSLEVLASELDLPVEGRG
CEEECCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKTQTADQITEARRESHLFYLSSLRRPLIDRAEGIYMWTQDGRRFIDGSSGPMVANIGH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCEEEECCC
SNRNVLDAMKRQMDRATFAYRLHFENEPAEELARELAKKLPEGMDRIFFVSGGSEATESC
CCHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
IKLARQWAVATGQASRWKVITRFPSYHGGTLGSLSITGDDALAETFEPMMRVMPTVPAPT
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
AWRDRDNLSMEQRGVRYADMLEEKILAEGPESVVAFIMEPIGGAATAALVAPDSYYARTR
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHEEEEECCCHHHHHHH
EICDHYGILLIHDEVMCGAGRTGKFLGGDHWNCKPDIVALSKGLGSGYAPLGALAAPMRL
HHHHHCCEEEEECCEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHH
VQPLLASGGFQHGHTYAGNPLACAAGLAVLGEMDRLDLIANAAAMGDVLMDGLKGLAKRF
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFIADVRGKGLLTGAEMVADPETLRPIEQGKKATQRLLDLAYERGLIIYGRRVKGGVDGD
CEEEECCCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECEECCCCCCC
NFMVAPPMIVTSEQVGEIISIIGDSLEVLASELDLPVEGRG
CEEECCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]