Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 134302799

GI number: 134302799

Start: 1892638

End: 1893663

Strand: Reverse

Name: trpD [H]

Synonym: FTW_2023

Alternate gene names: 134302799

Gene position: 1893663-1892638 (Counterclockwise)

Preceding gene: 134302800

Following gene: 134302798

Centisome position: 99.75

GC content: 30.51

Gene sequence:

>1026_bases
ATGGGTACAACAATGATTAGTCTAAAAAGTATTGTTGATAAACTTTATAATTTAGAAGACCTTAGTTACCAAGAAAGTTA
TCAGCTTTTTGATTATTTTATTAAAGGTCAAATAGAGTTACCTTTACAAACTAGTATATTGACAGCACTTAAGTTAAAAA
AAGAAACTTCGATAGAAATAGCAGCTGCAGTAGAAGCTTTATTTGATAATACTAAAGAGTTTCCAAAAATAAAGGGAGAT
TTAGCTGGCATAGTTGGTACTGGTGGAGATGGATTTAATACTATTAATATTTCTACAACAGCTGCTATTGTTGCTGCTAC
TGCTGGTTATAAAGTAGCTAAACATGGTGGTCGTAGTGTATCAAGTAAATCTGGATCTTTTGATCTTTTAGAATCTTTTG
GTGTAAATATAGAATTAGCACCTGATCAAACAAAACAATGTTTAGAACTATATAATCTGGGATTTTTATTTGTACCTTTT
TATAGTGACGGCTTTAGACACATAAAAGAGGCTAGAACTATCTTAAAAACTAGAACTATTTTTAATATTTTAGGACCTTT
AATAAATCCAGCTAGACCGAATAAGGTTGTGATAGGAGTTTACTCAAAAGACTTAATTTTGCCAATGGCAAAAACTTTGG
TCAATCTTGGGATAGACAGAGCCGTAGTGGTATATGGAAGTGGTTTAGATGAGGTAGCAATACATGATGATACTTATGTT
GCTGAAATACAAAATAATCAGATAATCGAATATAAAGTTTCTCCTGTAGATTTTGGTATAGATACATATGCAATCAAAGA
TCTTGAAGGTGGCTTACCAGAGCAGAATAGAGAGATTATAAAACAAATACTTCTAGGTAAAGGTAAAGAAGCTCATAATG
CTGCTGTGGCTGTAAATGTTGCTATGCTTATGAAGCTTTATGATAAGGATGATTTAAAACAAAATACTCAAGAAGTATTA
GAAATAATTAAGTCTGGAAAGTGTTTTAATATATTACAACAAGTTATAAATTATAGTAATAAATAG

Upstream 100 bases:

>100_bases
TGGCTGTAGTAGATGATAAAAATAAGGTATGTGGTTTACAATTTCATCCTGAATCAATAATGACTATACATGGTTCTAAA
CTTTTAGATAATATAGTTAA

Downstream 100 bases:

>100_bases
ATTATTCTAATAATACCATTACTATTTATCTTTTGATTTTTAATTCTTTTCATAATAAATTTTGTTATATTTTAAATATA
AATATAAATATAAATATAAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGTTMISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILTALKLKKETSIEIAAAVEALFDNTKEFPKIKGD
LAGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSVSSKSGSFDLLESFGVNIELAPDQTKQCLELYNLGFLFVPF
YSDGFRHIKEARTILKTRTIFNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYV
AEIQNNQIIEYKVSPVDFGIDTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNVAMLMKLYDKDDLKQNTQEVL
EIIKSGKCFNILQQVINYSNK

Sequences:

>Translated_341_residues
MGTTMISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILTALKLKKETSIEIAAAVEALFDNTKEFPKIKGD
LAGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSVSSKSGSFDLLESFGVNIELAPDQTKQCLELYNLGFLFVPF
YSDGFRHIKEARTILKTRTIFNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYV
AEIQNNQIIEYKVSPVDFGIDTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNVAMLMKLYDKDDLKQNTQEVL
EIIKSGKCFNILQQVINYSNK
>Mature_340_residues
GTTMISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILTALKLKKETSIEIAAAVEALFDNTKEFPKIKGDL
AGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSVSSKSGSFDLLESFGVNIELAPDQTKQCLELYNLGFLFVPFY
SDGFRHIKEARTILKTRTIFNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYVA
EIQNNQIIEYKVSPVDFGIDTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNVAMLMKLYDKDDLKQNTQEVLE
IIKSGKCFNILQQVINYSNK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=324, Percent_Identity=50, Blast_Score=300, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6320561, Length=330, Percent_Identity=32.4242424242424, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37538; Mature: 37407

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTMISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILTALKLKKETSIEI
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCHHHHHHHHHHHCCCCCHHH
AAAVEALFDNTKEFPKIKGDLAGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSV
HHHHHHHHHCHHHCCCCCCCCCEEEECCCCCCEEEEEEHHHHHHHHHCCCHHHHCCCCCC
SSKSGSFDLLESFGVNIELAPDQTKQCLELYNLGFLFVPFYSDGFRHIKEARTILKTRTI
CCCCCCHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
FNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYV
HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCEE
AEIQNNQIIEYKVSPVDFGIDTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNV
EEECCCEEEEEEECCEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
AMLMKLYDKDDLKQNTQEVLEIIKSGKCFNILQQVINYSNK
HHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GTTMISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILTALKLKKETSIEI
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCHHHHHHHHHHHCCCCCHHH
AAAVEALFDNTKEFPKIKGDLAGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSV
HHHHHHHHHCHHHCCCCCCCCCEEEECCCCCCEEEEEEHHHHHHHHHCCCHHHHCCCCCC
SSKSGSFDLLESFGVNIELAPDQTKQCLELYNLGFLFVPFYSDGFRHIKEARTILKTRTI
CCCCCCHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
FNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYV
HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCEE
AEIQNNQIIEYKVSPVDFGIDTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNV
EEECCCEEEEEEECCEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
AMLMKLYDKDDLKQNTQEVLEIIKSGKCFNILQQVINYSNK
HHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA