Click here to switch to the map view.

The map label for this gene is aspS [H]

Identifier: 134302781

GI number: 134302781

Start: 1871595

End: 1873367

Strand: Reverse

Name: aspS [H]

Synonym: FTW_1997

Alternate gene names: 134302781

Gene position: 1873367-1871595 (Counterclockwise)

Preceding gene: 134302783

Following gene: 134302770

Centisome position: 98.68

GC content: 35.14

Gene sequence:

>1773_bases
ATGAGAACACATTATAGTTCAGATATTAATGAAAAATTACAAGGACAAAAAGTTACAGTATGCGGTTGGGTTCATCGTCG
TAGAGATCACGGTGGTGTTATTTTCTTAGATATTAGAGATAGAACTGGTTTGGTACAATTAGTTTTTAACCCTGATAATG
ACAATTTCAAAGTTGCTGATAGTTTAAGATCTGAATTTGTGATTAAAGCTGAAGGTGTTGTTAACTTAAGACCAGAAGGT
CAAGAAAACAAAAATATTTCTAGTGGTAAAGTTGAGATAATTGGTGATAGTATAGAGGTTATTAATAAATCTAAAACTAT
TCCATTTCAGTTAGATGATTTCCAATCAACAGGCGAAGATGTCAAACTTAAGTATCGTTATATTGATCTGCGTCGTCCAG
AAATGCAACATAAATTAATTACGCGTTCAAAGGCGATTAGATATGTACGTAACTTTCTAGATAATAATGGTTTTCTTGAT
ATCGAAACGCCATTTTTAACAAAAGCAACACCAGAGGGTGCTAGAGATTATCTTGTGCCAAGTCGTAATTTTAATGGTAA
GTTTTATGCATTGCCGCAATCGCCACAACTTTTCAAACAGCTATTGATGGTTTCAGGTTTTGATAGATATTATCAAATCG
TTAAATGTTTCCGTGATGAAGATTTAAGAGCTGATAGACAGCCAGAATTTACCCAGATAGATATTGAAGCTTCATTTATT
GATGAGGCTTTTATCATGTCGACTATGGAGAGAATGATAGCGGGACTTTTCAAAGAAACTATCGGTGTTGAGTTTGCAAC
TCCTTTCCAAGTAATGACTTTTGCTGATGCTATTGATAAGTATGGTTCAGATAAACCTGATCTAAGAATTCCACTTGAAT
TTGTAAATATCAAAGAAGATATGCAAAACGAAGAGTTTAAGGTATTTTCAGGTCCAGCAAATGATCCACAATCGCGAGTT
ATTGCGCTGAGAATTCCTGGCGGTAATGATAAGCTTACGCGTAAGATGATCGATGAGTATACCAAGTTTGTTGGTATCTA
CGGTGCTAAAGGTCTTGCATATATCAAGATTAATTCATTATCACAAGGCAAAGAGGGCTTACAATCACCAATTGTAAAAA
ATATCTCCGAAGAAACCTTGTTCAAAGTGATTGAGAAAACTAGCGCTAAAGAGGGTGATTTATTATTCTTTGGTGCTGGT
AAGGCTAAGATTGTAAATGATTCAATGGGTGCATTAAGAGCTAAGATTGGTGAAGATCTTGATCTATTTAATAAAGATTG
GGCACCATTATGGGTTGTTGATTTCCCAATGTTTGAGAAAGATGATAATCGTTTATATGCAATGCATCATCCATTTACAG
CTCCTAAAGTTAGTTCAGTTGAAGACTTAGTTAATACTAATCCAGAAGAGCTAAGCTCAAGAGCATACGATATGGTTATT
AATGGTTATGAAGTAGGTGGTGGATCTATCCGTATTCATAAACAAGATATCCAAGCAAAAGTATTTAACTTATTGGGCAT
TTCTGATGATGAAGCTCGTGAGAAGTTTGGCTTTATGCTTGACGCTTTATCATATGGTACACCTATTCATGGTGGTATAG
CTTTTGGTGTTGATAGACTTATTATGCTGCTTACAGGAACCACAAATATCCGTGATGTAATAGCATTCCCTAAAACTCAA
ACGGCGAGCTGTTTAATGACAGAAGCACCATCAACAGTTTCTTTAGAGCAGCTTAATGAGCTTGGTATAGCTGTTAAGAA
AGAAGAAAGGTAA

Upstream 100 bases:

>100_bases
AATATTTGTGCTTAGTCTTCTTTGTCATTTCCTGCTATAATAATGTGATTAATTTTATCTATTTAAATTATTATAAAAAT
TTTAAAGGGTTAGTTTGGAT

Downstream 100 bases:

>100_bases
GCGCAAATTAATATTTTTGTTACTGCTTTAACTTAAAAATTATAATAATATAAATCACTCTAATAATTCTTTTATAAATA
CTAAAATGTATAATAAATCT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVADSLRSEFVIKAEGVVNLRPEG
QENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGEDVKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLD
IETPFLTKATPEGARDYLVPSRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFI
DEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKEDMQNEEFKVFSGPANDPQSRV
IALRIPGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSLSQGKEGLQSPIVKNISEETLFKVIEKTSAKEGDLLFFGAG
KAKIVNDSMGALRAKIGEDLDLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVI
NGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGVDRLIMLLTGTTNIRDVIAFPKTQ
TASCLMTEAPSTVSLEQLNELGIAVKKEER

Sequences:

>Translated_590_residues
MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVADSLRSEFVIKAEGVVNLRPEG
QENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGEDVKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLD
IETPFLTKATPEGARDYLVPSRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFI
DEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKEDMQNEEFKVFSGPANDPQSRV
IALRIPGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSLSQGKEGLQSPIVKNISEETLFKVIEKTSAKEGDLLFFGAG
KAKIVNDSMGALRAKIGEDLDLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVI
NGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGVDRLIMLLTGTTNIRDVIAFPKTQ
TASCLMTEAPSTVSLEQLNELGIAVKKEER
>Mature_590_residues
MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVADSLRSEFVIKAEGVVNLRPEG
QENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGEDVKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLD
IETPFLTKATPEGARDYLVPSRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFI
DEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKEDMQNEEFKVFSGPANDPQSRV
IALRIPGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSLSQGKEGLQSPIVKNISEETLFKVIEKTSAKEGDLLFFGAG
KAKIVNDSMGALRAKIGEDLDLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVI
NGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGVDRLIMLLTGTTNIRDVIAFPKTQ
TASCLMTEAPSTVSLEQLNELGIAVKKEER

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=603, Percent_Identity=39.8009950248756, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI5031815, Length=289, Percent_Identity=27.681660899654, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI194272210, Length=289, Percent_Identity=27.3356401384083, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI45439306, Length=240, Percent_Identity=30.4166666666667, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4758762, Length=284, Percent_Identity=26.4084507042254, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI226491502, Length=258, Percent_Identity=24.8062015503876, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1788173, Length=591, Percent_Identity=58.5448392554992, Blast_Score=712, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=320, Percent_Identity=25.3125, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789256, Length=304, Percent_Identity=24.3421052631579, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32566633, Length=607, Percent_Identity=35.0906095551895, Blast_Score=339, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI71994340, Length=313, Percent_Identity=24.2811501597444, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17535925, Length=313, Percent_Identity=24.2811501597444, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17535927, Length=313, Percent_Identity=24.2811501597444, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71984122, Length=291, Percent_Identity=27.4914089347079, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17551876, Length=334, Percent_Identity=25.748502994012, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=627, Percent_Identity=34.9282296650718, Blast_Score=300, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6320242, Length=260, Percent_Identity=27.3076923076923, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321807, Length=285, Percent_Identity=27.3684210526316, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=266, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584738, Length=611, Percent_Identity=36.0065466448445, Blast_Score=349, Evalue=4e-96,
Organism=Drosophila melanogaster, GI24640849, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640851, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136276, Length=303, Percent_Identity=26.4026402640264, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921528, Length=280, Percent_Identity=27.1428571428571, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 66728; Mature: 66728

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVAD
CCCCCCCCHHHHHCCCEEEEEEHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCEEEHH
SLRSEFVIKAEGVVNLRPEGQENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGED
HHCCCEEEEECCEEEECCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCEEECCCCCCCCC
VKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLDIETPFLTKATPEGARDYLVP
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCCCCCCC
SRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFI
CCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHH
DEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKED
HHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCCCEEEEHEEECCHHH
MQNEEFKVFSGPANDPQSRVIALRIPGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSL
CCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCEEEEEECCC
SQGKEGLQSPIVKNISEETLFKVIEKTSAKEGDLLFFGAGKAKIVNDSMGALRAKIGEDL
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEECCHHHHHHHHHCCCH
DLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVI
HHCCCCCCCEEEEECCCEECCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHEEEEE
NGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGVDRL
EEEEECCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IMLLTGTTNIRDVIAFPKTQTASCLMTEAPSTVSLEQLNELGIAVKKEER
HHEEECCCCCHHHEECCCCCCCEEEEECCCCCCCHHHHHHCCCEEECCCC
>Mature Secondary Structure
MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVAD
CCCCCCCCHHHHHCCCEEEEEEHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCEEEHH
SLRSEFVIKAEGVVNLRPEGQENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGED
HHCCCEEEEECCEEEECCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCEEECCCCCCCCC
VKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLDIETPFLTKATPEGARDYLVP
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCCCCCCC
SRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFI
CCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHH
DEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKED
HHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCCCEEEEHEEECCHHH
MQNEEFKVFSGPANDPQSRVIALRIPGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSL
CCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCEEEEEECCC
SQGKEGLQSPIVKNISEETLFKVIEKTSAKEGDLLFFGAGKAKIVNDSMGALRAKIGEDL
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEECCHHHHHHHHHCCCH
DLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVI
HHCCCCCCCEEEEECCCEECCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHEEEEE
NGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGVDRL
EEEEECCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IMLLTGTTNIRDVIAFPKTQTASCLMTEAPSTVSLEQLNELGIAVKKEER
HHEEECCCCCHHHEECCCCCCCEEEEECCCCCCCHHHHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA